{"id":14264,"date":"2020-03-22T06:25:08","date_gmt":"2020-03-22T06:25:08","guid":{"rendered":"http:\/\/evaggelatos.com\/?p=14264"},"modified":"2020-03-22T06:32:55","modified_gmt":"2020-03-22T06:32:55","slug":"%ce%bf%ce%b9-%cf%85%cf%80%ce%b5%cf%81%cf%84%ce%b1%cf%83%ce%b9%ce%ba%ce%bf%ce%af-%ce%b1%cf%83%ce%b8%ce%b5%ce%bd%ce%b5%ce%af%cf%82-%ce%b8%ce%b5%cf%89%cf%81%ce%bf%cf%8d%ce%bd%cf%84%ce%b1%ce%b9-%cf%89-2","status":"publish","type":"post","link":"https:\/\/evaggelatos.com\/?p=14264","title":{"rendered":"\u039f\u03b9 \u03c5\u03c0\u03b5\u03c1\u03c4\u03b1\u03c3\u03b9\u03ba\u03bf\u03af \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03b8\u03b5\u03c9\u03c1\u03bf\u03cd\u03bd\u03c4\u03b1\u03b9 \u03c9\u03c2 \u03bf\u03bc\u03ac\u03b4\u03b1 \u03c5\u03c8\u03b7\u03bb\u03bf\u03cd \u03ba\u03b9\u03bd\u03b4\u03cd\u03bd\u03bf\u03c5 \u03b3\u03b9\u03b1 \u03c3\u03bf\u03b2\u03b1\u03c1\u03ae \u03bb\u03bf\u03af\u03bc\u03c9\u03be\u03b7 \u03b1\u03c0\u03cc \u03c4\u03bf\u03bd \u03ba\u03bf\u03c1\u03c9\u03bd\u03bf\u03ca\u03cc; \u039c\u03ad\u03c1\u03bf\u03c2 2\u03bf"},"content":{"rendered":"

\u0397 \u03bb\u03bf\u03c3\u03b1\u03c1\u03c4\u03ac\u03bd\u03b7 \u03ae\u03c4\u03b1\u03bd \u03bf \u03c0\u03c1\u03ce\u03c4\u03bf\u03c2 \u03bc\u03b7 \u03c0\u03b5\u03c0\u03c4\u03b9\u03b4\u03b9\u03ba\u03cc\u03c2 \u03b1\u03bd\u03c4\u03b1\u03b3\u03c9\u03bd\u03b9\u03c3\u03c4\u03ae\u03c2 \u03c4\u03c9\u03bd \u03c5\u03c0\u03bf\u03b4\u03bf\u03c7\u03ad\u03c9\u03bd \u03c4\u03b7\u03c2 \u03b1\u03b3\u03b3\u03b5\u03b9\u03bf\u03c4\u03b5\u03bd\u03c3\u03af\u03bd\u03b7\u03c2 II \u03c0\u03bf\u03c5 \u03c7\u03c1\u03b7\u03c3\u03b9\u03bc\u03bf\u03c0\u03bf\u03b9\u03ae\u03b8\u03b7\u03ba\u03b5 \u03c9\u03c2 \u03b1\u03bd\u03c4\u03b9\u03c5\u03c0\u03b5\u03c1\u03c4\u03b1\u03c3\u03b9\u03ba\u03cc \u03c6\u03ac\u03c1\u03bc\u03b1\u03ba\u03bf. \u0388\u03ba\u03c4\u03bf\u03c4\u03b5 \u03ad\u03c7\u03bf\u03c5\u03bd \u03b5\u03b9\u03c3\u03b1\u03c7\u03b8\u03b5\u03af \u03ba\u03b1\u03b9 \u03ba\u03b1\u03c4\u03b1\u03c7\u03c9\u03c1\u03b7\u03b8\u03b5\u03af \u03c0\u03bf\u03bb\u03bb\u03ac \u03c6\u03ac\u03c1\u03bc\u03b1\u03ba\u03b1 \u03b2\u03b1\u03c3\u03b9\u03c3\u03bc\u03ad\u03bd\u03b1 \u03c3\u03b5 \u03b1\u03c5\u03c4\u03ae \u03c4\u03b7\u03bd \u03b1\u03c1\u03c7\u03ae. \u0397 \u03b4\u03b9\u03c6\u03b1\u03b9\u03bd\u03c5\u03bb\u03b9\u03ba\u03ae \u03b4\u03bf\u03bc\u03ae \u03b5\u03af\u03bd\u03b1\u03b9 \u03c7\u03b1\u03c1\u03b1\u03ba\u03c4\u03b7\u03c1\u03b9\u03c3\u03c4\u03b9\u03ba\u03ae \u03c4\u03c9\u03bd \u03c0\u03b5\u03c1\u03b9\u03c3\u03c3\u03bf\u03c4\u03ad\u03c1\u03c9\u03bd \u03b1\u03bb\u03bb\u03ac \u03cc\u03c7\u03b9 \u03cc\u03bb\u03c9\u03bd \u03c4\u03c9\u03bd \u03b1\u03bd\u03c4\u03b1\u03b3\u03c9\u03bd\u03b9\u03c3\u03c4\u03ce\u03bd \u03c4\u03c9\u03bd \u03c5\u03c0\u03bf\u03b4\u03bf\u03c7\u03ad\u03c9\u03bd \u03c4\u03b7\u03c2 \u03b1\u03b3\u03b3\u03b5\u03b9\u03bf\u03c4\u03b5\u03bd\u03c3\u03af\u03bd\u03b7\u03c2 \u0399\u0399 \u03ba\u03b1\u03b9 \u03c0\u03bf\u03bb\u03bb\u03bf\u03af \u03b5\u03be \u03b1\u03c5\u03c4\u03ce\u03bd \u03c0\u03b5\u03c1\u03b9\u03ad\u03c7\u03bf\u03c5\u03bd \u03ad\u03bd\u03b1 \u03b9\u03bc\u03b9\u03b4\u03b1\u03b6\u03bf\u03bb\u03b9\u03ba\u03cc \u03c3\u03c4\u03bf\u03b9\u03c7\u03b5\u03af\u03bf \u03c4\u03bf \u03bf\u03c0\u03bf\u03af\u03bf \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03ae \u03b4\u03b5 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03c3\u03c5\u03bc\u03c0\u03c5\u03ba\u03bd\u03c9\u03b8\u03b5\u03af \u03bc\u03b5 \u03ac\u03bb\u03bb\u03bf\u03c5\u03c2 \u03c0\u03c5\u03c1\u03ae\u03bd\u03b5\u03c2.<\/p>\n\n\n\n\n\n\n\n\n\n\n\n
\u03a6\u03b1\u03c1\u03bc\u03b1\u03ba\u03b5\u03c5\u03c4\u03b9\u03ba\u03ae \u03bf\u03c5\u03c3\u03af\u03b1<\/strong><\/td>\n\u03a7\u03c1\u03cc\u03bd\u03bf\u03c2 \u03b7\u03bc\u03af\u03c3\u03b5\u03b9\u03b1\u03c2 \u03b6\u03c9\u03ae\u03c2<\/strong><\/p>\n

(\u03ce\u03c1\u03b5\u03c2)<\/strong><\/td>\n

\u0391\u03c0\u03bf\u03b2\u03bf\u03bb\u03ae<\/strong><\/p>\n

\u039d\u03b5\u03c6\u03c1\u03b9\u03ba\u03ae\/\u0397\u03c0\u03b1\u03c4\u03b9\u03ba\u03ae (%)<\/strong><\/td>\n

\u0395\u03bc\u03c0\u03bf\u03c1\u03b9\u03ba\u03ae \u03bf\u03bd\u03bf\u03bc\u03b1\u03c3\u03af\u03b1\/(+HCT)<\/strong><\/td>\n\u0394\u03bf\u03c3\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03cc \u03b5\u03cd\u03c1\u03bf\u03c2<\/strong><\/p>\n

(mg)<\/strong><\/td>\n<\/tr>\n

\u039b\u03bf\u03c3\u03b1\u03c1\u03c4\u03ac\u03bd\u03b7<\/strong><\/td>\n2<\/strong><\/td>\n10\/90<\/strong><\/td>\nCozaar\u00ae<\/sup>\/ Hyzaar\u00ae<\/sup><\/strong><\/td>\n80-320<\/strong><\/td>\n<\/tr>\n
\u0392\u03b1\u03bb\u03c3\u03b1\u03c1\u03c4\u03ac\u03bd\u03b7<\/strong><\/td>\n6<\/strong><\/td>\n30\/70<\/strong><\/td>\nDiovan\u00ae<\/sup>\/ Co-Diovan\u00ae<\/sup><\/strong><\/td>\n80-320<\/strong><\/td>\n<\/tr>\n
\u03a4\u03b5\u03bb\u03bc\u03b9\u03c3\u03b1\u03c1\u03c4\u03ac\u03bd\u03b7<\/strong><\/td>\n24<\/strong><\/td>\n1\/99<\/strong><\/td>\nMicardis\u00ae<\/sup>\/ Micardis Plus\u00ae<\/sup><\/strong><\/td>\n20-80<\/strong><\/td>\n<\/tr>\n
\u039a\u03b1\u03bd\u03b4\u03b5\u03c3\u03b1\u03c1\u03c4\u03ac\u03bd\u03b7<\/strong><\/td>\n9<\/strong><\/td>\n60\/40<\/strong><\/td>\nAtacand\u00ae<\/sup>\/ Atacand Plus\u00ae<\/sup><\/strong><\/td>\n8-32<\/strong><\/td>\n<\/tr>\n
\u0399\u03c1\u03bc\u03c0\u03b5\u03c3\u03b1\u03c1\u03c4\u03ac\u03bd\u03b7<\/strong><\/td>\n11-15<\/strong><\/td>\n1\/99<\/strong><\/td>\nAprovel\u00ae<\/sup>\/ Co-Aprovel\u00ae<\/sup><\/strong><\/td>\n150-300<\/strong><\/td>\n<\/tr>\n
\u0395\u03c0\u03c1\u03bf\u03c3\u03b1\u03c1\u03c4\u03ac\u03bd\u03b7<\/strong><\/td>\n5<\/strong><\/td>\n30\/70<\/strong><\/td>\nTeveten\u00ae<\/sup>\/ Teveten Plus\u00ae<\/sup><\/strong><\/td>\n400-800<\/strong><\/td>\n<\/tr>\n
\u039f\u03bb\u03bc\u03b5\u03c3\u03b1\u03c1\u03c4\u03ac\u03bd\u03b7<\/strong><\/td>\n14-16<\/strong><\/td>\n40\/60<\/strong><\/td>\nOlmetec\u00ae<\/sup>\/ Olmetec Plus\u00ae<\/sup><\/strong><\/td>\n10-40<\/strong><\/td>\n<\/tr>\n
\u0391\u03b6\u03b9\u03bb\u03c3\u03b1\u03c1\u03c4\u03ac\u03bd\u03b7<\/strong><\/td>\n11<\/strong><\/td>\n55\/42<\/strong><\/td>\nEdarbi\u00ae<\/sup><\/strong><\/td>\n20-80<\/strong><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n\n\n\n
\u038c\u03bb\u03b5\u03c2 \u03b1\u03c5\u03c4\u03ad\u03c2 \u03bf\u03b9 \u03bf\u03c5\u03c3\u03af\u03b5\u03c2 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b5\u03ba\u03bb\u03b5\u03ba\u03c4\u03b9\u03ba\u03ad\u03c2 \u03b3\u03b9\u03b1 \u03c4\u03bf\u03bd \u03c5\u03c0\u03bf\u03b4\u03bf\u03c7\u03ad\u03b1 \u0391\u03a41<\/sub> \u03c4\u03b7\u03c2 \u03b1\u03b3\u03b3\u03b5\u03b9\u03bf\u03c4\u03b5\u03bd\u03c3\u03af\u03bd\u03b7\u03c2 \u0399\u0399. \u039f\u03b9 \u03b5\u03bb\u03b5\u03cd\u03b8\u03b5\u03c1\u03b1 \u03c0\u03c1\u03bf\u03c3\u03b2\u03ac\u03c3\u03b9\u03bc\u03bf\u03b9 \u03c5\u03c0\u03bf\u03b4\u03bf\u03c7\u03b5\u03af\u03c2 \u0391\u03a42<\/sub> \u03b8\u03b1 \u03b5\u03bd\u03b5\u03c1\u03b3\u03bf\u03c0\u03bf\u03b9\u03b7\u03b8\u03bf\u03cd\u03bd \u03b1\u03c0\u03cc \u03c5\u03c8\u03b7\u03bb\u03ac \u03b5\u03c0\u03af\u03c0\u03b5\u03b4\u03b1 \u03b5\u03bd\u03b4\u03bf\u03b3\u03b5\u03bd\u03bf\u03cd\u03c2 \u03b1\u03b3\u03b3\u03b5\u03b9\u03bf\u03c4\u03b5\u03bd\u03c3\u03af\u03bd\u03b7\u03c2 II \u03b7 \u03bf\u03c0\u03bf\u03af\u03b1 \u03c0\u03c1\u03bf\u03ba\u03cd\u03c0\u03c4\u03b5\u03b9 \u03b1\u03c0\u03cc \u03b1\u03bd\u03c4\u03b1\u03bd\u03b1\u03ba\u03bb\u03b1\u03c3\u03c4\u03b9\u03ba\u03cc \u03bc\u03b7\u03c7\u03b1\u03bd\u03b9\u03c3\u03bc\u03cc \u03c0\u03bf\u03c5 \u03c3\u03c7\u03b5\u03c4\u03af\u03b6\u03b5\u03c4\u03b1\u03b9 \u03bc\u03b5 \u03c4\u03b7\u03bd \u03b1\u03b3\u03b3\u03b5\u03b9\u03bf\u03b4\u03b9\u03b1\u03c3\u03c4\u03bf\u03bb\u03ae \u03ba\u03b1\u03b9 \u03bc\u03b5\u03af\u03c9\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03b1\u03c5\u03be\u03b7\u03bc\u03ad\u03bd\u03b7\u03c2 \u03b1\u03c1\u03c4\u03b7\u03c1\u03b9\u03b1\u03ba\u03ae\u03c2 \u03c0\u03af\u03b5\u03c3\u03b7\u03c2. \u0397 \u03b4\u03b9\u03ad\u03b3\u03b5\u03c1\u03c3\u03b7 \u03c4\u03bf\u03c5 \u03c5\u03c0\u03bf\u03b4\u03bf\u03c7\u03ad\u03b1 \u0391\u03a42<\/sub> \u03b8\u03b5\u03c9\u03c1\u03b5\u03af\u03c4\u03b1\u03b9 \u03cc\u03c4\u03b9 \u03b5\u03af\u03bd\u03b1\u03b9 \u03ad\u03bd\u03b1 \u03b5\u03c0\u03b9\u03b8\u03c5\u03bc\u03b7\u03c4\u03cc \u03c6\u03b1\u03b9\u03bd\u03cc\u03bc\u03b5\u03bd\u03bf \u03c0\u03bf\u03c5 \u03b5\u03c0\u03ac\u03b3\u03b5\u03b9 \u03b1\u03b3\u03b3\u03b5\u03b9\u03bf\u03b4\u03b9\u03b1\u03c3\u03c4\u03bf\u03bb\u03ae \u03ba\u03b1\u03b9 \u03ad\u03c7\u03b5\u03b9 \u03b1\u03bd\u03c4\u03b9\u03c0\u03bf\u03bb\u03bb\u03b1\u03c0\u03bb\u03b1\u03c3\u03b9\u03b1\u03c3\u03c4\u03b9\u03ba\u03ae \u03b4\u03c1\u03ac\u03c3\u03b7 \u03c3\u03c4\u03b1 \u03b1\u03b3\u03b3\u03b5\u03af\u03b1.<\/em><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

\u039f\u03b9 \u03ba\u03c5\u03ba\u03bb\u03bf\u03c6\u03bf\u03c1\u03bf\u03cd\u03bd\u03c4\u03b5\u03c2 \u03b1\u03bd\u03c4\u03b1\u03b3\u03c9\u03bd\u03b9\u03c3\u03c4\u03ad\u03c2 \u03c4\u03c9\u03bd \u03c5\u03c0\u03bf\u03b4\u03bf\u03c7\u03ad\u03c9\u03bd \u0391\u03a41<\/sub> \u03c4\u03b7\u03c2 \u03b1\u03b3\u03b3\u03b5\u03b9\u03bf\u03c4\u03b5\u03bd\u03c3\u03af\u03bd\u03b7\u03c2 \u0399\u0399 \u03b5\u03af\u03bd\u03b1\u03b9 \u03bc\u03b1\u03ba\u03c1\u03ac\u03c2 \u03b4\u03b9\u03ac\u03c1\u03ba\u03b5\u03b9\u03b1\u03c2 \u03b4\u03c1\u03ac\u03c3\u03b7\u03c2 \u03b5\u03c0\u03b9\u03c4\u03c1\u03ad\u03c0\u03bf\u03bd\u03c4\u03b1\u03c2 \u03ad\u03c4\u03c3\u03b9 \u03c4\u03b7\u03bd \u03c7\u03bf\u03c1\u03ae\u03b3\u03b7\u03c3\u03ae \u03c4\u03bf\u03c5\u03c2 \u03ac\u03c0\u03b1\u03be \u03b7\u03bc\u03b5\u03c1\u03b7\u03c3\u03af\u03c9\u03c2 \u03b3\u03b9\u03b1 \u03c4\u03b7\u03bd \u03c1\u03cd\u03b8\u03bc\u03b9\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03b1\u03c1\u03c4\u03b7\u03c1\u03b9\u03b1\u03ba\u03ae\u03c2 \u03c0\u03af\u03b5\u03c3\u03b7\u03c2 \u03ba\u03b1\u03b9 \u03bc\u03c0\u03bf\u03c1\u03bf\u03cd\u03bd \u03bd\u03b1 \u03c3\u03c5\u03bd\u03b4\u03c5\u03b1\u03c3\u03c4\u03bf\u03cd\u03bd \u03bc\u03b5 \u03ac\u03bb\u03bb\u03bf\u03c5\u03c2 \u03c4\u03cd\u03c0\u03bf\u03c5\u03c2 \u03b1\u03bd\u03c4\u03b9\u03c5\u03c0\u03b5\u03c1\u03c4\u03b1\u03c3\u03b9\u03ba\u03ce\u03bd. \u039f \u03c3\u03c5\u03bd\u03b4\u03c5\u03b1\u03c3\u03bc\u03cc\u03c2 \u03b5\u03bd\u03cc\u03c2 \u03b1\u03bd\u03c4\u03b1\u03b3\u03c9\u03bd\u03b9\u03c3\u03c4\u03ae \u03c4\u03c9\u03bd \u03c5\u03c0\u03bf\u03b4\u03bf\u03c7\u03ad\u03c9\u03bd \u0391\u03a41<\/sub> \u03c4\u03b7\u03c2 \u03b1\u03b3\u03b3\u03b5\u03b9\u03bf\u03c4\u03b5\u03bd\u03c3\u03af\u03bd\u03b7\u03c2 \u0399\u0399 \u03ba\u03b1\u03b9 \u03b8\u03b5\u03b9\u03b1\u03b6\u03b9\u03b4\u03b9\u03ba\u03bf\u03cd \u03b4\u03b9\u03bf\u03c5\u03c1\u03b7\u03c4\u03b9\u03ba\u03bf\u03cd \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03b5\u03af \u03c3\u03ae\u03bc\u03b5\u03c1\u03b1 \u03bc\u03b9\u03b1 \u03b9\u03c3\u03c7\u03c5\u03c1\u03ae \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03c5\u03c4\u03b9\u03ba\u03ae \u03b1\u03b3\u03c9\u03b3\u03ae \u03c4\u03b7\u03c2 \u03b1\u03c1\u03c4\u03b7\u03c1\u03b9\u03b1\u03ba\u03ae\u03c2 \u03c5\u03c0\u03ad\u03c1\u03c4\u03b1\u03c3\u03b7\u03c2.<\/p>\n

\u0397 \u03b1\u03bd\u03c4\u03b9\u03c5\u03c0\u03b5\u03c1\u03c4\u03b1\u03c3\u03b9\u03ba\u03ae \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03b5\u03c3\u03bc\u03b1\u03c4\u03b9\u03ba\u03cc\u03c4\u03b7\u03c4\u03b1 \u03ba\u03b1\u03b9 \u03b7 \u03c0\u03c1\u03bf\u03c3\u03c4\u03b1\u03c4\u03b5\u03c5\u03c4\u03b9\u03ba\u03ae \u03b4\u03c1\u03ac\u03c3\u03b7 \u03b5\u03bd\u03ac\u03bd\u03c4\u03b9\u03b1 \u03c3\u03c4\u03b1 \u03b5\u03b3\u03ba\u03b5\u03c6\u03b1\u03bb\u03b9\u03ba\u03ac \u03ba\u03b1\u03b9 \u03ba\u03b1\u03c1\u03b4\u03b9\u03b1\u03b3\u03b3\u03b5\u03b9\u03b1\u03ba\u03ac \u03c3\u03c5\u03bc\u03b2\u03ac\u03bc\u03b1\u03c4\u03b1 \u03c4\u03c9\u03bd \u03b4\u03b9\u03b1\u03c6\u03cc\u03c1\u03c9\u03bd \u03b1\u03bd\u03c4\u03b1\u03b3\u03c9\u03bd\u03b9\u03c3\u03c4\u03ce\u03bd \u03c4\u03c9\u03bd \u03c5\u03c0\u03bf\u03b4\u03bf\u03c7\u03ad\u03c9\u03bd \u0391\u03a41<\/sub> \u03c4\u03b7\u03c2 \u03b1\u03b3\u03b3\u03b5\u03b9\u03bf\u03c4\u03b5\u03bd\u03c3\u03af\u03bd\u03b7\u03c2 \u0399\u0399 \u03ad\u03c7\u03bf\u03c5\u03bd \u03ba\u03b1\u03c4\u03b1\u03b3\u03c1\u03b1\u03c6\u03b5\u03af \u03b1\u03c0\u03cc \u03b4\u03b9\u03ac\u03c6\u03bf\u03c1\u03b5\u03c2 \u03c4\u03c5\u03c7\u03b1\u03b9\u03bf\u03c0\u03bf\u03b9\u03b7\u03bc\u03ad\u03bd\u03b5\u03c2 \u03b5\u03c0\u03b9\u03b4\u03b7\u03bc\u03b9\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ad\u03c2 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b5\u03c2 \u03cc\u03c0\u03c9\u03c2 \u03b7 LIFE, \u03b7 SCOPE, \u03b7 VALUE \u03ba\u03b1\u03b9 \u03ac\u03bb\u03bb\u03b5\u03c2, \u03b5\u03bd\u03ce \u03b7 \u03c0\u03c1\u03bf\u03c3\u03c4\u03b1\u03c4\u03b5\u03c5\u03c4\u03b9\u03ba\u03ae \u03b4\u03c1\u03ac\u03c3\u03b7 \u03b5\u03bd\u03ac\u03bd\u03c4\u03b9\u03b1 \u03c3\u03c4\u03b7\u03bd \u03c0\u03c1\u03c9\u03c4\u03b5\u03ca\u03bd\u03bf\u03c5\u03c1\u03af\u03b1\/\u03bd\u03b5\u03c6\u03c1\u03bf\u03c0\u03ac\u03b8\u03b5\u03b9\u03b1 \u03ad\u03c7\u03b5\u03b9 \u03b5\u03c0\u03b9\u03b2\u03b5\u03b2\u03b1\u03b9\u03c9\u03b8\u03b5\u03af \u03bc\u03b5 \u03c0\u03bf\u03bb\u03bb\u03ad\u03c2 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b5\u03c2 \u03cc\u03c0\u03c9\u03c2 \u03b7 RENAL, \u03b7 IDTN \u03ba\u03b1\u03b9 \u03ac\u03bb\u03bb\u03b5\u03c2.<\/p>\n

\u039f\u03b9 \u03c9\u03c6\u03ad\u03bb\u03b9\u03bc\u03b5\u03c2 \u03b4\u03c1\u03ac\u03c3\u03b5\u03b9\u03c2 \u03c4\u03b7\u03c2 \u03ba\u03b1\u03bd\u03b4\u03b5\u03c3\u03b1\u03c1\u03c4\u03ac\u03bd\u03b7\u03c2 \u03ba\u03b1\u03b9 \u03c4\u03b7\u03c2 \u03b2\u03b1\u03bb\u03c3\u03b1\u03c1\u03c4\u03ac\u03bd\u03b7\u03c2 \u03c3\u03c4\u03b7\u03bd \u03c3\u03c5\u03bc\u03c6\u03bf\u03c1\u03b7\u03c4\u03b9\u03ba\u03ae \u03ba\u03b1\u03c1\u03b4\u03b9\u03b1\u03ba\u03ae \u03b1\u03bd\u03b5\u03c0\u03ac\u03c1\u03ba\u03b5\u03b9\u03b1 \u03ad\u03c7\u03bf\u03c5\u03bd \u03ba\u03b1\u03c4\u03b1\u03b3\u03c1\u03b1\u03c6\u03b5\u03af \u03c3\u03b5 \u03b5\u03c0\u03b9\u03b4\u03b7\u03bc\u03b9\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ad\u03c2 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b5\u03c2 \u03cc\u03c0\u03c9\u03c2 \u03b7 CHARM \u03ba\u03b1\u03b9 \u03b7 VAL-HEFT, \u03b1\u03bd\u03c4\u03af\u03c3\u03c4\u03bf\u03b9\u03c7\u03b1 \u03ba\u03b1\u03b9 \u03b5\u03bd\u03b4\u03b5\u03af\u03ba\u03bd\u03c5\u03bd\u03c4\u03b1\u03b9 \u03c3\u03c4\u03b7\u03bd \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1 \u03c4\u03b7\u03c2 \u03c3\u03c5\u03bc\u03c6\u03bf\u03c1\u03b7\u03c4\u03b9\u03ba\u03ae\u03c2 \u03ba\u03b1\u03c1\u03b4\u03b9\u03b1\u03ba\u03ae\u03c2 \u03b1\u03bd\u03b5\u03c0\u03ac\u03c1\u03ba\u03b5\u03b9\u03b1\u03c2.<\/p>\n

\u039f\u03b9 \u03b4\u03b9\u03b1\u03c6\u03bf\u03c1\u03ad\u03c2 \u03bc\u03b5\u03c4\u03b1\u03be\u03cd \u03c4\u03c9\u03bd \u03b4\u03b9\u03b1\u03c6\u03cc\u03c1\u03c9\u03bd \u03b4\u03b9\u03b1\u03b8\u03b5\u03c3\u03af\u03bc\u03c9\u03bd \u03b1\u03bd\u03c4\u03b1\u03b3\u03c9\u03bd\u03b9\u03c3\u03c4\u03ce\u03bd \u03c4\u03c9\u03bd \u03c5\u03c0\u03bf\u03b4\u03bf\u03c7\u03ad\u03c9\u03bd \u0391\u03a41<\/sub> \u03c4\u03b7\u03c2 \u03b1\u03b3\u03b3\u03b5\u03b9\u03bf\u03c4\u03b5\u03bd\u03c3\u03af\u03bd\u03b7\u03c2 \u0399\u0399 \u03b4\u03b5\u03bd \u03b5\u03af\u03bd\u03b1\u03b9 \u03b5\u03bd\u03c4\u03c5\u03c0\u03c9\u03c3\u03b9\u03b1\u03ba\u03ad\u03c2. \u0395\u03bd\u03b4\u03b5\u03b9\u03ba\u03c4\u03b9\u03ba\u03ac \u03b1\u03bd\u03b1\u03c6\u03ad\u03c1\u03b5\u03c4\u03b1\u03b9 \u03cc\u03c4\u03b9, \u03b7 \u03bb\u03bf\u03c3\u03b1\u03c1\u03c4\u03ac\u03bd\u03b7 \u03c0\u03b1\u03c1\u03ad\u03c7\u03b5\u03b9 \u03b5\u03c0\u03b9\u03c0\u03c1\u03cc\u03c3\u03b8\u03b5\u03c4\u03b7 \u03bf\u03c5\u03c1\u03b9\u03ba\u03bf\u03b4\u03b9\u03bf\u03c5\u03c1\u03b9\u03c4\u03b9\u03ba\u03ae \u03b4\u03c1\u03ac\u03c3\u03b7 \u03c0\u03bf\u03c5 \u03b4\u03b5\u03bd \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03b5\u03af \u03b4\u03c1\u03ac\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03ba\u03b1\u03c4\u03b7\u03b3\u03bf\u03c1\u03af\u03b1\u03c2 \u03c4\u03c9\u03bd \u03b1\u03bd\u03c4\u03b1\u03b3\u03c9\u03bd\u03b9\u03c3\u03c4\u03ce\u03bd \u03c4\u03c9\u03bd \u03c5\u03c0\u03bf\u03b4\u03bf\u03c7\u03ad\u03c9\u03bd \u0391\u03a41<\/sub> \u03c4\u03b7\u03c2 \u03b1\u03b3\u03b3\u03b5\u03b9\u03bf\u03c4\u03b5\u03bd\u03c3\u03af\u03bd\u03b7\u03c2 \u0399\u0399, \u03b7 \u03b5\u03c0\u03c1\u03bf\u03c3\u03b1\u03c1\u03c4\u03ac\u03bd\u03b7 \u03b1\u03bd\u03b1\u03c3\u03c4\u03ad\u03bb\u03bb\u03b5\u03b9 \u03c4\u03b7\u03bd \u03b1\u03c0\u03b5\u03bb\u03b5\u03c5\u03b8\u03ad\u03c1\u03c9\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03bd\u03bf\u03c1\u03b1\u03b4\u03c1\u03b5\u03bd\u03b1\u03bb\u03af\u03bd\u03b7\u03c2 \u03b1\u03c0\u03cc \u03c4\u03b9\u03c2 \u03c3\u03c5\u03bc\u03c0\u03b1\u03b8\u03b7\u03c4\u03b9\u03ba\u03ad\u03c2 \u03bd\u03b5\u03c5\u03c1\u03b9\u03ba\u03ad\u03c2 \u03b1\u03c0\u03bf\u03bb\u03ae\u03be\u03b5\u03b9\u03c2, \u03c0\u03bf\u03c5 \u03c0\u03c1\u03bf\u03ba\u03b1\u03bb\u03b5\u03af\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03bf\u03bd \u03b1\u03c0\u03bf\u03ba\u03bb\u03b5\u03b9\u03c3\u03bc\u03cc \u03c4\u03c9\u03bd \u03c0\u03c1\u03bf\u03c3\u03c5\u03bd\u03b1\u03c0\u03c4\u03b9\u03ba\u03ce\u03bd \u03c5\u03c0\u03bf\u03b4\u03bf\u03c7\u03ad\u03c9\u03bd \u0391\u03a41<\/sub>,<\/strong> \u03b7 \u03c4\u03b5\u03bb\u03bc\u03b9\u03c3\u03b1\u03c1\u03c4\u03ac\u03bd\u03b7 \u03bc\u03b5 \u03bc\u03b1\u03ba\u03c1\u03ac \u03b4\u03b9\u03ac\u03c1\u03ba\u03b5\u03b9\u03b1 \u03b4\u03c1\u03ac\u03c3\u03b7\u03c2, \u03ad\u03c7\u03b5\u03b9 \u03b4\u03c5\u03bd\u03b7\u03c4\u03b9\u03ba\u03ac \u03b5\u03c5\u03bd\u03bf\u03ca\u03ba\u03cc\u03c4\u03b5\u03c1\u03bf \u03bc\u03b5\u03c4\u03b1\u03b2\u03bf\u03bb\u03b9\u03ba\u03cc \u03c0\u03c1\u03bf\u03c6\u03af\u03bb, \u03bb\u03cc\u03b3\u03c9 \u03c4\u03b7\u03c2 \u03b4\u03b9\u03ad\u03b3\u03b5\u03c1\u03c3\u03b7\u03c2 \u03c4\u03bf\u03c5 \u03c5\u03c0\u03cc\u03c4\u03c5\u03c0\u03bf\u03c5 \u03b3 \u03c4\u03bf\u03c5 \u03c5\u03c0\u03bf\u03b4\u03bf\u03c7\u03ad\u03b1 \u03c0\u03bf\u03c5 \u03b5\u03bd\u03b5\u03c1\u03b3\u03bf\u03c0\u03bf\u03b9\u03b5\u03af\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c0\u03b1\u03c1\u03ac\u03b3\u03bf\u03bd\u03c4\u03b5\u03c2 \u03c0\u03bf\u03c5 \u03b5\u03c0\u03ac\u03b3\u03bf\u03c5\u03bd \u03c4\u03bf\u03bd \u03c0\u03bf\u03bb\u03bb\u03b1\u03c0\u03bb\u03b1\u03c3\u03b9\u03b1\u03c3\u03bc\u03cc \u03c4\u03c9\u03bd \u03c5\u03c0\u03b5\u03c1\u03bf\u03be\u03b5\u03b9\u03c3\u03c9\u03bc\u03ac\u03c4\u03c9\u03bd (PPAR-\u03b3) \u03ba\u03b1\u03b9 \u03b7 \u03b2\u03b1\u03bb\u03c3\u03b1\u03c1\u03c4\u03ac\u03bd\u03b7 \u03b5\u03bc\u03c6\u03b1\u03bd\u03af\u03b6\u03b5\u03b9 \u03c0\u03bf\u03bb\u03cd \u03c5\u03c8\u03b7\u03bb\u03ae \u03b5\u03ba\u03bb\u03b5\u03ba\u03c4\u03b9\u03ba\u03cc\u03c4\u03b7\u03c4\u03b1 \u03b3\u03b9\u03b1 \u03c4\u03bf\u03bd \u03c5\u03c0\u03bf\u03b4\u03bf\u03c7\u03ad\u03b1 \u0391\u03a41 \u03ba\u03b1\u03b9 \u03b9\u03c3\u03c7\u03c5\u03c1\u03cc\u03c4\u03b5\u03c1\u03b7 \u03b5\u03bd\u03b5\u03c1\u03b3\u03bf\u03c0\u03bf\u03af\u03b7\u03c3\u03b7 \u03c4\u03bf\u03c5 \u03c5\u03c0\u03bf\u03b4\u03bf\u03c7\u03ad\u03b1 \u0391\u03a42<\/sub>.<\/p>\n

\u03a3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03cc \u03c0\u03bb\u03b5\u03bf\u03bd\u03ad\u03ba\u03c4\u03b7\u03bc\u03b1 \u03c4\u03c9\u03bd \u03b1\u03bd\u03c4\u03b1\u03b3\u03c9\u03bd\u03b9\u03c3\u03c4\u03ce\u03bd \u03c4\u03c9\u03bd \u03c5\u03c0\u03bf\u03b4\u03bf\u03c7\u03ad\u03c9\u03bd \u0391\u03a41<\/sub>\u03c4\u03b7\u03c2 \u03b1\u03b3\u03b3\u03b5\u03b9\u03bf\u03c4\u03b5\u03bd\u03c3\u03af\u03bd\u03b7\u03c2 \u0399\u0399 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b7 \u03c4\u03ad\u03bb\u03b5\u03b9\u03b1 \u03b1\u03bd\u03bf\u03c7\u03ae \u03c4\u03bf\u03c5\u03c2 \u03b1\u03c0\u03cc \u03c4\u03bf\u03c5\u03c2 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2. \u039f\u03b9 \u03bc\u03ad\u03c7\u03c1\u03b9 \u03c4\u03ce\u03c1\u03b1 \u03b1\u03bd\u03b1\u03c6\u03b5\u03c1\u03cc\u03bc\u03b5\u03bd\u03b5\u03c2 \u03c0\u03b1\u03c1\u03b5\u03bd\u03ad\u03c1\u03b3\u03b5\u03b9\u03b5\u03c2 \u03b4\u03b5\u03bd \u03c6\u03b1\u03af\u03bd\u03b5\u03c4\u03b1\u03b9 \u03bd\u03b1 \u03b4\u03b9\u03b1\u03c6\u03ad\u03c1\u03bf\u03c5\u03bd \u03b1\u03c5\u03c4\u03ce\u03bd \u03c4\u03bf\u03c5 \u03b5\u03b9\u03ba\u03bf\u03bd\u03b9\u03ba\u03bf\u03cd \u03c6\u03b1\u03c1\u03bc\u03ac\u03ba\u03bf\u03c5. \u0393\u03b9\u03b1 \u03c0\u03b1\u03c1\u03ac\u03b4\u03b5\u03b9\u03b3\u03bc\u03b1, \u03bf\u03b9 \u03b1\u03bd\u03c4\u03b1\u03b3\u03c9\u03bd\u03b9\u03c3\u03c4\u03ad\u03c2 \u03c4\u03c9\u03bd \u03c5\u03c0\u03bf\u03b4\u03bf\u03c7\u03ad\u03c9\u03bd \u0391\u03a41<\/sub> \u03c4\u03b7\u03c2 \u03b1\u03b3\u03b3\u03b5\u03b9\u03bf\u03c4\u03b5\u03bd\u03c3\u03af\u03bd\u03b7\u03c2 \u0399\u0399 \u03b4\u03b5\u03bd \u03c0\u03c1\u03bf\u03ba\u03b1\u03bb\u03bf\u03cd\u03bd \u03b2\u03ae\u03c7\u03b1 \u03c3\u03b5 \u03b1\u03bd\u03c4\u03af\u03b8\u03b5\u03c3\u03b7 \u03bc\u03b5 \u03c4\u03bf\u03c5\u03c2 \u03b1\u03bd\u03b1\u03c3\u03c4\u03bf\u03bb\u03b5\u03af\u03c2 \u03c4\u03bf\u03c5 \u03bc\u03b5\u03c4\u03b1\u03c4\u03c1\u03b5\u03c0\u03c4\u03b9\u03ba\u03bf\u03cd \u03b5\u03bd\u03b6\u03cd\u03bc\u03bf\u03c5 \u03c4\u03b7\u03c2 \u03b1\u03b3\u03b3\u03b5\u03b9\u03bf\u03c4\u03b5\u03bd\u03c3\u03af\u03bd\u03b7\u03c2 (\u03b1\u039c\u0395\u0391) \u03ba\u03b1\u03b9 \u03c4\u03bf \u03b1\u03b3\u03b3\u03b5\u03b9\u03bf\u03bd\u03b5\u03c5\u03c1\u03c9\u03c4\u03b9\u03ba\u03cc \u03bf\u03af\u03b4\u03b7\u03bc\u03b1 \u03c3\u03b1\u03bd \u03c0\u03b1\u03c1\u03b5\u03bd\u03ad\u03c1\u03b3\u03b5\u03b9\u03b1 \u03ad\u03c7\u03b5\u03b9 \u03b1\u03bd\u03b1\u03c6\u03b5\u03c1\u03b8\u03b5\u03af \u03c0\u03bf\u03bb\u03cd \u03c3\u03c0\u03ac\u03bd\u03b9\u03b1.<\/p>\n

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\u039f\u03b9 \u03b1\u03bd\u03c4\u03b1\u03b3\u03c9\u03bd\u03b9\u03c3\u03c4\u03ad\u03c2 \u03c4\u03c9\u03bd \u03c5\u03c0\u03bf\u03b4\u03bf\u03c7\u03ad\u03c9\u03bd \u0391\u03a41<\/sub> \u03c4\u03b7\u03c2 \u03b1\u03b3\u03b3\u03b5\u03b9\u03bf\u03c4\u03b5\u03bd\u03c3\u03af\u03bd\u03b7\u03c2 \u0399\u0399 \u03b1\u03bd\u03b1\u03b3\u03bd\u03c9\u03c1\u03af\u03b6\u03bf\u03bd\u03c4\u03b1\u03b9 \u03c3\u03ae\u03bc\u03b5\u03c1\u03b1 \u03c9\u03c2 \u03c6\u03ac\u03c1\u03bc\u03b1\u03ba\u03b1 \u03c0\u03c1\u03ce\u03c4\u03b7\u03c2 \u03b5\u03ba\u03bb\u03bf\u03b3\u03ae\u03c2 \u03ba\u03b1\u03b9 \u03b1\u03bd\u03b1\u03c6\u03ad\u03c1\u03bf\u03bd\u03c4\u03b1\u03b9 \u03bc\u03b1\u03b6\u03af \u03bc\u03b5 \u03ac\u03bb\u03bb\u03b5\u03c2 \u03c4\u03ad\u03c3\u03c3\u03b5\u03c1\u03b9\u03c2 \u03ba\u03b1\u03c4\u03b7\u03b3\u03bf\u03c1\u03af\u03b5\u03c2 \u03b1\u03bd\u03c4\u03b9\u03c5\u03c0\u03b5\u03c1\u03c4\u03b1\u03c3\u03b9\u03ba\u03ce\u03bd \u03c0\u03b1\u03c1\u03b1\u03b3\u03cc\u03bd\u03c4\u03c9\u03bd \u03c3\u03b5 \u03ba\u03b1\u03c4\u03b5\u03c5\u03b8\u03c5\u03bd\u03c4\u03ae\u03c1\u03b9\u03b5\u03c2 \u03bf\u03b4\u03b7\u03b3\u03af\u03b5\u03c2 \u03cc\u03c0\u03c9\u03c2 \u03b1\u03c5\u03c4\u03ad\u03c2 \u03c4\u03bf\u03c5 ESG-ESC 2003.) \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03bf\u03cd\u03bd \u03c3\u03ae\u03bc\u03b5\u03c1\u03b1 \u03c4\u03bf\u03bd \u03c0\u03c5\u03c1\u03ae\u03bd\u03b1 \u03c4\u03bf\u03c5 \u03b1\u03bb\u03b3\u03bf\u03c1\u03af\u03b8\u03bc\u03bf\u03c5 \u03c4\u03b7\u03c2 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1\u03c2 \u03c4\u03b7\u03c2 \u03b1\u03c1\u03c4\u03b7\u03c1\u03b9\u03b1\u03ba\u03ae\u03c2 \u03c5\u03c0\u03ad\u03c1\u03c4\u03b1\u03c3\u03b7\u03c2, \u03cc\u03c0\u03c9\u03c2 \u03b1\u03c5\u03c4\u03cc \u03b1\u03c0\u03bf\u03c4\u03c5\u03c0\u03ce\u03bd\u03b5\u03c4\u03b1\u03b9 \u03c3\u03c4\u03b9\u03c2 \u03ba\u03b1\u03c4\u03b5\u03c5\u03b8\u03c5\u03bd\u03c4\u03ae\u03c1\u03b9\u03b5\u03c2 \u03bf\u03b4\u03b7\u03b3\u03af\u03b5\u03c2 \u03c4\u03b7\u03c2 \u0395\u03c5\u03c1\u03c9\u03c0\u03b1\u03ca\u03ba\u03ae\u03c2 \u039a\u03b1\u03c1\u03b4\u03b9\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ae\u03c2 \u0395\u03c4\u03b1\u03b9\u03c1\u03b5\u03af\u03b1\u03c2 (ESC) \u03ba\u03b1\u03b9 \u03c4\u03b7\u03c2 \u0395\u03c5\u03c1\u03c9\u03c0\u03b1\u03ca\u03ba\u03ae\u03c2 \u0395\u03c4\u03b1\u03b9\u03c1\u03b5\u03af\u03b1\u03c2 \u03a5\u03c0\u03ad\u03c1\u03c4\u03b1\u03c3\u03b7\u03c2 (ESH), \u03c0\u03bf\u03c5 \u03b5\u03ba\u03b4\u03cc\u03b8\u03b7\u03ba\u03b1\u03bd \u03c4\u03bf 2018 (8). \u0397 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1 \u03bc\u03b5 \u0391CEIs \u03ba\u03b1\u03b9 ARBs, \u03b5\u03c0\u03b9\u03b4\u03c1\u03ac \u03b4\u03b9\u03b1\u03c6\u03bf\u03c1\u03b5\u03c4\u03b9\u03ba\u03ac \u03c3\u03c4\u03b1 \u03b5\u03c0\u03b9\u03bc\u03ad\u03c1\u03bf\u03c5\u03c2 \u03c3\u03c5\u03c3\u03c4\u03ae\u03bc\u03b1\u03c4\u03b1 \u03b1\u03bd\u03b1\u03c4\u03c1\u03bf\u03c6\u03bf\u03b4\u03cc\u03c4\u03b7\u03c3\u03b7\u03c2 (feedback loops) \u03ba\u03b1\u03b9 \u03c3\u03c4\u03b7 \u03b4\u03c1\u03b1\u03c3\u03c4\u03b7\u03c1\u03b9\u03cc\u03c4\u03b7\u03c4\u03b1 \u03b5\u03c0\u03b9\u03bc\u03ad\u03c1\u03bf\u03c5\u03c2 \u03c3\u03c5\u03c3\u03c4\u03b1\u03c4\u03b9\u03ba\u03ce\u03bd \u03c4\u03bf\u03c5 \u03a3\u03a1\u0391.<\/p>\n

\u039c\u03b5\u03bb\u03ad\u03c4\u03b5\u03c2 \u03c3\u03b5 \u03b6\u03c9\u03b9\u03ba\u03ac \u03bc\u03bf\u03bd\u03c4\u03ad\u03bb\u03b1 \u03ad\u03b4\u03b5\u03b9\u03be\u03b1\u03bd \u03c0\u03c9\u03c2 \u03b7 \u03c7\u03c1\u03ae\u03c3\u03b7 \u03b1\u03bd\u03b1\u03c3\u03c4\u03bf\u03bb\u03ad\u03c9\u03bd \u03c4\u03bf\u03c5 \u03c3\u03c5\u03c3\u03c4\u03ae\u03bc\u03b1\u03c4\u03bf\u03c2 \u03a3\u03a1\u0391<\/strong> \u03bc\u03c0\u03bf\u03c1\u03bf\u03cd\u03bd \u03b4\u03c5\u03bd\u03b7\u03c4\u03b9\u03ba\u03ce\u03c2 \u03bd\u03b1 \u03b1\u03c5\u03be\u03ae\u03c3\u03bf\u03c5\u03bd \u03c4\u03b7\u03bd \u03ad\u03ba\u03c6\u03c1\u03b1\u03c3\u03b7 \u03c4\u03bf\u03c5 ACE-2 \u03ba\u03b1\u03b9 \u03ad\u03c4\u03c3\u03b9 \u03c5\u03c0\u03bf\u03c3\u03c4\u03b7\u03c1\u03af\u03b6\u03b5\u03c4\u03b1\u03b9 \u03b7 \u03c5\u03c0\u03cc\u03b8\u03b5\u03c3\u03b7 \u03c0\u03c9\u03c2 \u03b7 \u03c7\u03c1\u03ae\u03c3\u03b7 \u03c4\u03bf\u03c5\u03c2 \u03c3\u03b5 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b1\u03c5\u03be\u03ac\u03bd\u03b5\u03b9 \u03c4\u03b7 \u03bb\u03bf\u03b9\u03bc\u03bf\u03b3\u03bf\u03bd\u03b9\u03ba\u03cc\u03c4\u03b7\u03c4\u03b1 \u03c4\u03bf\u03c5 COVID-19, \u03bc\u03ad\u03c3\u03c9 \u03b1\u03cd\u03be\u03b7\u03c3\u03b7\u03c2 \u03c4\u03bf\u03c5 \u03c6\u03bf\u03c1\u03c4\u03af\u03bf\u03c5 \u03c4\u03bf\u03c5 \u03b9\u03bf\u03cd \u03c0\u03bf\u03c5 \u03b5\u03b9\u03c3\u03ad\u03c1\u03c7\u03b5\u03c4\u03b1\u03b9 \u03b5\u03bd\u03b4\u03bf\u03ba\u03c5\u03c4\u03c4\u03ac\u03c1\u03b9\u03b1.<\/u><\/strong><\/p>\n

\u0397 \u03c5\u03c0\u03b5\u03c1\u03ad\u03ba\u03c6\u03c1\u03b1\u03c3\u03b7 (upregulation) \u03c4\u03bf\u03c5 ACE-2 \u03bc\u03b5 \u03c4\u03b7\u03bd \u03c7\u03c1\u03ae\u03c3\u03b7 \u03b1\u03bd\u03b1\u03c3\u03c4\u03bf\u03bb\u03ad\u03c9\u03bd \u03a3\u03a1\u0391 \u03ad\u03c7\u03b5\u03b9 \u03b5\u03c5\u03c1\u03ad\u03c9\u03c2 \u03ba\u03b1\u03c4\u03b1\u03b4\u03b5\u03b9\u03c7\u03c4\u03b5\u03af \u03c3\u03c4\u03b7 \u03ba\u03b1\u03c1\u03b4\u03b9\u03ac, \u03c3\u03c4\u03b1 \u03b1\u03b3\u03b3\u03b5\u03af\u03b1, \u03c3\u03c4\u03bf\u03c5\u03c2 \u03bd\u03b5\u03c6\u03c1\u03bf\u03cd\u03c2, \u03b1\u03bd \u03ba\u03b1\u03b9 \u03b4\u03b5\u03bd \u03c5\u03c0\u03ac\u03c1\u03c7\u03bf\u03c5\u03bd \u03c3\u03b1\u03c6\u03ae \u03b4\u03b5\u03b4\u03bf\u03bc\u03ad\u03bd\u03b1 \u03cc\u03c4\u03b9 \u03ba\u03ac\u03c4\u03b9 \u03b1\u03bd\u03c4\u03af\u03c3\u03c4\u03bf\u03b9\u03c7\u03bf \u03c3\u03c5\u03bc\u03b2\u03b1\u03af\u03bd\u03b5\u03b9 \u03c3\u03c4\u03bf\u03bd \u03c0\u03bd\u03b5\u03cd\u03bc\u03bf\u03bd\u03b1 \u03ae \u03c3\u03c4\u03b7\u03bd \u03b1\u03bd\u03b1\u03c0\u03bd\u03b5\u03c5\u03c3\u03c4\u03b9\u03ba\u03ae \u03bf\u03b4\u03cc. \u03a0\u03b5\u03c1\u03b9\u03bf\u03c1\u03b9\u03c3\u03bc\u03ad\u03bd\u03b1 \u03b4\u03b5\u03b4\u03bf\u03bc\u03ad\u03bd\u03b1 \u03cc\u03bc\u03c9\u03c2 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b4\u03b9\u03b1\u03b8\u03ad\u03c3\u03b9\u03bc\u03b1 \u03c0\u03bf\u03c5 \u03bd\u03b1 \u03b5\u03c0\u03b9\u03b2\u03b5\u03b2\u03b1\u03b9\u03ce\u03bd\u03bf\u03c5\u03bd \u03c4\u03b7\u03bd \u03c5\u03c0\u03b5\u03c1\u03ad\u03ba\u03c6\u03c1\u03b1\u03c3\u03b7 \u03c4\u03c9\u03bd ACEI-2 \u03c3\u03c4\u03bf\u03c5\u03c2 \u03b1\u03bd\u03b8\u03c1\u03ce\u03c0\u03bf\u03c5\u03c2 \u03bc\u03b5\u03c4\u03ac \u03c7\u03bf\u03c1\u03ae\u03b3\u03b7\u03c3\u03b7 \u03b1\u03bd\u03b1\u03c3\u03c4\u03bf\u03bb\u03ad\u03c9\u03bd \u03a3\u03a1\u0391. \u03a5\u03c0\u03ac\u03c1\u03c7\u03bf\u03c5\u03bd \u03b4\u03b5\u03b4\u03bf\u03bc\u03ad\u03bd\u03b1 \u03c0\u03bf\u03c5 \u03c5\u03c0\u03bf\u03c3\u03c4\u03b7\u03c1\u03af\u03b6\u03bf\u03c5\u03bd \u03cc\u03c4\u03b9 \u03b7 \u03c5\u03c0\u03b5\u03c1\u03ad\u03ba\u03c6\u03c1\u03b1\u03c3\u03b7 \u03c4\u03bf\u03c5 ACE-2 \u03b5\u03bc\u03c6\u03b1\u03bd\u03af\u03b6\u03b5\u03c4\u03b1\u03b9 \u03b9\u03c3\u03c7\u03c5\u03c1\u03cc\u03c4\u03b5\u03c1\u03b7 \u03ba\u03b1\u03b9 \u03c0\u03b9\u03bf \u03c3\u03c4\u03b1\u03b8\u03b5\u03c1\u03ae \u03bc\u03b5 \u03c4\u03b7 \u03c7\u03c1\u03ae\u03c3\u03b7 \u03c4\u03c9\u03bd ARBs \u03c3\u03b5 \u03c3\u03cd\u03b3\u03ba\u03c1\u03b9\u03c3\u03b7 \u03bc\u03b5 \u03c4\u03bf\u03c5\u03c2 ACEIs (9,10,11).<\/p>\n

\u039c\u03ad\u03c7\u03c1\u03b9 \u03c4\u03ce\u03c1\u03b1, \u03b4\u03b5\u03bd \u03c5\u03c6\u03af\u03c3\u03c4\u03b1\u03bd\u03c4\u03b1\u03b9 \u03c0\u03b5\u03b9\u03c3\u03c4\u03b9\u03ba\u03ac \u03b4\u03b5\u03b4\u03bf\u03bc\u03ad\u03bd\u03b1, \u03cc\u03c4\u03b9 \u03c4\u03c5\u03c7\u03cc\u03bd \u03c5\u03c0\u03b5\u03c1\u03ad\u03ba\u03c6\u03c1\u03b1\u03c3\u03b7 \u03c4\u03bf\u03c5 ACE2 \u03b1\u03c0\u03cc \u03b1\u03bd\u03b1\u03c3\u03c4\u03bf\u03bb\u03b5\u03af\u03c2 \u03c4\u03bf\u03c5 \u03c3\u03c5\u03c3\u03c4\u03ae\u03bc\u03b1\u03c4\u03bf\u03c2 RAS, \u03b8\u03b1 \u03bc\u03c0\u03bf\u03c1\u03bf\u03cd\u03c3\u03b5 \u03bd\u03b1 \u03b1\u03c5\u03be\u03ae\u03c3\u03b5\u03b9 \u03b4\u03c5\u03bd\u03b7\u03c4\u03b9\u03ba\u03ac \u03c4\u03bf\u03bd \u03ba\u03af\u03bd\u03b4\u03c5\u03bd\u03bf \u03bd\u03cc\u03c3\u03b7\u03c3\u03b7\u03c2 \u03ba\u03b1\u03b9 \u03bd\u03b1 \u03b5\u03c0\u03b9\u03b4\u03b5\u03b9\u03bd\u03ce\u03c3\u03b5\u03b9 \u03c4\u03b7\u03bd \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03c0\u03bf\u03c1\u03b5\u03af\u03b1 \u03c4\u03b7\u03c2 \u03bb\u03bf\u03af\u03bc\u03c9\u03be\u03b7\u03c2 \u03b1\u03c0\u03cc \u03c4\u03bf\u03bd COVID-19. \u0391\u03c0\u03cc \u03c4\u03b7\u03bd \u03ac\u03bb\u03bb\u03b7 \u03c0\u03bb\u03b5\u03c5\u03c1\u03ac, \u03c5\u03c6\u03af\u03c3\u03c4\u03b1\u03bd\u03c4\u03b1\u03b9 \u03c0\u03b5\u03b9\u03c1\u03b1\u03bc\u03b1\u03c4\u03b9\u03ba\u03ac \u03b4\u03b5\u03b4\u03bf\u03bc\u03ad\u03bd\u03b1, \u03c3\u03cd\u03bc\u03c6\u03c9\u03bd\u03b1 \u03bc\u03b5 \u03c4\u03b1 \u03bf\u03c0\u03bf\u03af\u03b1 \u03b7 \u03b5\u03bd\u03b5\u03c1\u03b3\u03bf\u03c0\u03bf\u03af\u03b7\u03c3\u03b7 \u03c4\u03b7\u03c2 ANGII \u03c0\u03c1\u03bf\u03ac\u03b3\u03b5\u03b9, \u03b5\u03bd\u03ce \u03c4\u03bf ACE-2 \u03c0\u03c1\u03bf\u03b1\u03c3\u03c0\u03af\u03b6\u03b5\u03b9 \u03c4\u03b7\u03bd \u03b2\u03bb\u03ac\u03b2\u03b7 \u03c4\u03bf\u03c5 \u03c0\u03bd\u03b5\u03cd\u03bc\u03bf\u03bd\u03b1 (lung injury)<\/strong> (10-11) . \u03a6\u03b1\u03c1\u03bc\u03b1\u03ba\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ad\u03c2 \u03c0\u03b1\u03c1\u03b5\u03bc\u03b2\u03ac\u03c3\u03b5\u03b9\u03c2 \u03c3\u03b5 \u03b6\u03c9\u03b9\u03ba\u03ac \u03bc\u03bf\u03bd\u03c4\u03ad\u03bb\u03b1 \u03bc\u03b5 \u03c4\u03b7 \u03c7\u03c1\u03ae\u03c3\u03b7 \u03b1\u03bd\u03b1\u03c3\u03c4\u03bf\u03bb\u03ad\u03c9\u03bd \u03c4\u03bf\u03c5 \u03a3\u03a1\u0391 \u03ad\u03c7\u03bf\u03c5\u03bd \u03b4\u03b5\u03af\u03be\u03b5\u03b9 \u03c0\u03c1\u03bf\u03c3\u03c4\u03b1\u03c4\u03b5\u03c5\u03c4\u03b9\u03ba\u03ac \u03bf\u03c6\u03ad\u03bb\u03b7 \u03c3\u03b5 \u03b2\u03bb\u03ac\u03b2\u03b5\u03c2 \u03c4\u03bf\u03c5 \u03c0\u03bd\u03b5\u03cd\u03bc\u03bf\u03bd\u03b1 \u03ba\u03b1\u03b9 \u03c3\u03b5 \u03bc\u03bf\u03bd\u03c4\u03ad\u03bb\u03b1 \u03b9\u03bf\u03b3\u03b5\u03bd\u03ce\u03bd \u03bb\u03bf\u03b9\u03bc\u03ce\u03be\u03b5\u03c9\u03bd (9,10). \u039c\u03b5 \u03b2\u03ac\u03c3\u03b7 \u03b1\u03c5\u03c4\u03ad\u03c2 \u03c4\u03b9\u03c2 \u03c0\u03b1\u03c1\u03b1\u03c4\u03b7\u03c1\u03ae\u03c3\u03b5\u03b9\u03c2 \u03b7 \u03c7\u03c1\u03ae\u03c3\u03b7 \u03c4\u03c9\u03bd \u03b1\u03bd\u03b1\u03c3\u03c4\u03bf\u03bb\u03ad\u03c9\u03bd \u03c4\u03bf\u03c5 \u03a3\u03a1\u0391 \u03b8\u03b1 \u03bc\u03c0\u03bf\u03c1\u03bf\u03cd\u03c3\u03b5 \u03bd\u03b1 \u03c0\u03c1\u03bf\u03b1\u03c3\u03c0\u03af\u03b6\u03b5\u03b9 \u03ad\u03bd\u03b1\u03bd\u03c4\u03b9 \u03c4\u03b7\u03c2 \u03c0\u03b1\u03b8\u03bf\u03b3\u03bf\u03bd\u03b9\u03ba\u03cc\u03c4\u03b7\u03c4\u03b1\u03c2 \u03c4\u03bf\u03c5 \u03b9\u03bf\u03cd \u03c3\u03b5 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03c0\u03bf\u03c5 \u03c0\u03ac\u03c3\u03c7\u03bf\u03c5\u03bd \u03b1\u03c0\u03cc \u03c4\u03bf\u03bd COVID-19. \u0398\u03b1 \u03c0\u03c1\u03ad\u03c0\u03b5\u03b9 \u03bd\u03b1 \u03b4\u03b9\u03b5\u03c1\u03b5\u03c5\u03bd\u03b7\u03b8\u03b5\u03af \u03b5\u03ac\u03bd \u03c4\u03c5\u03c7\u03cc\u03bd \u03c0\u03bf\u03bb\u03c5\u03bc\u03bf\u03c1\u03c6\u03b9\u03c3\u03bc\u03bf\u03af \u03c4\u03bf\u03c5 ACE2, \u03c0\u03bf\u03c5 \u03c3\u03c5\u03bd\u03b4\u03ad\u03bf\u03bd\u03c4\u03b1\u03b9 \u03bc\u03b5 \u03c5\u03c0\u03ad\u03c1\u03c4\u03b1\u03c3\u03b7 \u03ba\u03b1\u03b9 \u03c4\u03bf\u03bd \u0394\u03b9\u03b1\u03b2\u03ae\u03c4\u03b7, \u03b9\u03b4\u03b9\u03b1\u03b9\u03c4\u03ad\u03c1\u03c9\u03c2 \u03bc\u03b5\u03c4\u03b1\u03be\u03cd \u0391\u03c3\u03b9\u03b1\u03c4\u03b9\u03ba\u03ce\u03bd \u03c0\u03bb\u03b7\u03b8\u03c5\u03c3\u03bc\u03ce\u03bd, \u03c0\u03b9\u03b8\u03b1\u03bd\u03ce\u03c2 \u03bd\u03b1\u00a0 \u03b4\u03b7\u03bb\u03ce\u03bd\u03bf\u03c5\u03bd \u03bc\u03b9\u03b1 \u03b3\u03b5\u03bd\u03b5\u03c4\u03b9\u03ba\u03ae \u03c0\u03c1\u03bf\u03b4\u03b9\u03ac\u03b8\u03b5\u03c3\u03b7 \u03bf\u03c1\u03b9\u03c3\u03bc\u03ad\u03bd\u03c9\u03bd \u03b3\u03b9\u03b1 \u03b1\u03c5\u03be\u03b7\u03bc\u03ad\u03bd\u03bf \u03ba\u03af\u03bd\u03b4\u03c5\u03bd\u03bf \u03bd\u03cc\u03c3\u03b7\u03c3\u03b7\u03c2 \u03b1\u03c0\u03cc \u03c4\u03bf\u03bd SARS-CoV-2.<\/p>\n

\u03a0\u03bf\u03b9\u03b1 \u03b7 \u03b8\u03ad\u03c3\u03b7 \u03c4\u03b7\u03c2 \u0395\u03c5\u03c1\u03c9\u03c0\u03b1\u03ca\u03ba\u03ae\u03c2 \u0395\u03c4\u03b1\u03b9\u03c1\u03b5\u03af\u03b1\u03c2 \u03a5\u03c0\u03ad\u03c1\u03c4\u03b1\u03c3\u03b7\u03c2 \u03b3\u03b9\u03b1 \u03c4\u03b7 \u03c3\u03c7\u03ad\u03c3\u03b7 \u03c5\u03c0\u03ad\u03c1\u03c4\u03b1\u03c3\u03b7\u03c2, \u03b1\u03bd\u03c4\u03b9\u03c5\u03c0\u03b5\u03c1\u03c4\u03b1\u03c3\u03b9\u03ba\u03ae\u03c2 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1\u03c2 \u03ba\u03b1\u03b9 \u03bb\u03bf\u03af\u03bc\u03c9\u03be\u03b7\u03c2 \u03bc\u03b5 \u03c4\u03bf\u03bd \u03ba\u03bf\u03c1\u03bf\u03bd\u03bf\u03ca\u03cc Covid-19;<\/strong><\/p>\n

\u03a0\u03c1\u03bf\u03c2 \u03c4\u03b7\u03bd \u03ba\u03b1\u03c4\u03b5\u03cd\u03b8\u03c5\u03bd\u03c3\u03b7 \u03b1\u03c5\u03c4\u03ae, \u03b7 \u0395\u03c5\u03c1\u03c9\u03c0\u03b1\u03ca\u03ba\u03ae \u0395\u03c4\u03b1\u03b9\u03c1\u03b5\u03af\u03b1 \u03a5\u03c0\u03ad\u03c1\u03c4\u03b1\u03c3\u03b7\u03c2 \u03b4\u03b7\u03bc\u03bf\u03c3\u03af\u03b5\u03c5\u03c3\u03b5 \u03c4\u03b7 \u03b5\u03c0\u03af\u03c3\u03b7\u03bc\u03b7 \u03b8\u03ad\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03c3\u03c4\u03bf \u03b8\u03ad\u03bc\u03b1 \u03b1\u03c5\u03c4\u03cc \u03bc\u03b5 \u03c4\u03b1 \u03ba\u03ac\u03c4\u03c9\u03b8\u03b9 5 \u03c3\u03b7\u03bc\u03b5\u03af\u03b1 ( \u03bc\u03b5 \u03c4\u03b7\u03bd \u03c0\u03c1\u03bf\u03c6\u03b1\u03bd\u03ae \u03b5\u03c0\u03b9\u03c6\u03cd\u03bb\u03b1\u03be\u03b7 \u03cc\u03c4\u03b9 \u03b7 \u03b4\u03ae\u03bb\u03c9\u03c3\u03b7 \u03b9\u03c3\u03c7\u03cd\u03b5\u03b9 \u03bc\u03b5 \u03b2\u03ac\u03c3\u03b7 \u03c4\u03b1 \u03c4\u03c9\u03c1\u03b9\u03bd\u03ac \u03b4\u03b5\u03b4\u03bf\u03bc\u03ad\u03bd\u03b1) (12).<\/p>\n

    \n
  1. \u0394\u03b5\u03bd \u03c5\u03c0\u03ac\u03c1\u03c7\u03b5\u03b9 \u03ba\u03b1\u03b8\u03b1\u03c1\u03ae \u03b1\u03c0\u03cc\u03b4\u03b5\u03b9\u03be\u03b7 \u03cc\u03c4\u03b9 \u03b7 \u03c5\u03c0\u03ad\u03c1\u03c4\u03b1\u03c3\u03b7 \u03b1\u03c5\u03c4\u03ae \u03ba\u03b1\u03b8\u2019 \u03b5\u03b1\u03c5\u03c4\u03ae \u03c3\u03c5\u03bd\u03b4\u03ad\u03b5\u03c4\u03b1\u03b9 \u03bc\u03b5 \u03b1\u03c5\u03be\u03b7\u03bc\u03ad\u03bd\u03bf \u03ba\u03af\u03bd\u03b4\u03c5\u03bd\u03bf \u03bc\u03cc\u03bb\u03c5\u03bd\u03c3\u03b7\u03c2 \u03bc\u03b5 COVID-19.<\/strong> \u03a3\u03c5\u03bd\u03b5\u03c0\u03ce\u03c2 \u03bf\u03b9 \u03c5\u03c0\u03b5\u03c1\u03c4\u03b1\u03c3\u03b9\u03ba\u03bf\u03af \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03b8\u03b1 \u03c0\u03c1\u03ad\u03c0\u03b5\u03b9 \u03bd\u03b1 \u03b1\u03ba\u03bf\u03bb\u03bf\u03c5\u03b8\u03bf\u03cd\u03bd \u03c4\u03b9\u03c2 \u03af\u03b4\u03b9\u03b5\u03c2 \u03c0\u03c1\u03bf\u03c6\u03c5\u03bb\u03ac\u03be\u03b5\u03b9\u03c2 \u03bc\u03b5 \u03c4\u03bf\u03c5\u03c2 \u03c3\u03c5\u03bd\u03bf\u03bc\u03b7\u03bb\u03af\u03ba\u03bf\u03c5\u03c2 \u03c4\u03bf\u03c5\u03c2 \u03ba\u03b1\u03b9 \u03c4\u03bf\u03c5\u03c2 \u03ad\u03c7\u03bf\u03bd\u03c4\u03b5\u03c2 \u03af\u03b4\u03b9\u03bf \u03c0\u03c1\u03bf\u03c6\u03af\u03bb \u03c3\u03c5\u03bd-\u03bd\u03bf\u03c3\u03b7\u03c1\u03bf\u03c4\u03ae\u03c4\u03c9\u03bd<\/li>\n
  2. \u03a3\u03b5 \u03c5\u03c0\u03b5\u03c1\u03c4\u03b1\u03c3\u03b9\u03ba\u03bf\u03cd\u03c2 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 \u03bc\u03cc\u03bb\u03c5\u03bd\u03c3\u03b7 COVID-19 \u03b7 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1 \u03bc\u03b5 ACEI \u03ae \u03b1\u03bd\u03b1\u03c3\u03c4\u03bf\u03bb\u03b5\u03af\u03c2 \u03c4\u03c9\u03bd \u03c5\u03c0\u03bf\u03b4\u03bf\u03c7\u03ad\u03c9\u03bd Ang II \u03c0\u03c1\u03ad\u03c0\u03b5\u03b9 \u03bd\u03b1 \u03c3\u03c5\u03bd\u03b5\u03c7\u03af\u03b6\u03b5\u03c4\u03b1\u03b9 \u03ba\u03b1\u03bd\u03bf\u03bd\u03b9\u03ba\u03ac \u03c5\u03c0\u03cc \u03c4\u03b9\u03c2 \u03bf\u03b4\u03b7\u03b3\u03af\u03b5\u03c2 \u03c4\u03c9\u03bd \u03b8\u03b5\u03c1\u03b1\u03c0\u03cc\u03bd\u03c4\u03c9\u03bd \u03b9\u03b1\u03c4\u03c1\u03ce\u03bd \u03b2\u03ac\u03c3\u03b5\u03b9 \u03c4\u03c9\u03bd 2018 ESC\/ESH \u03ba\u03b1\u03c4\u03b5\u03c5\u03b8\u03c5\u03bd\u03c4\u03ae\u03c1\u03b9\u03c9\u03bd \u03bf\u03b4\u03b7\u03b3\u03b9\u03ce\u03bd.<\/li>\n
  3. \u03a4\u03b1 \u03c5\u03c0\u03ac\u03c1\u03c7\u03bf\u03bd\u03c4\u03b1 \u03b4\u03b5\u03b4\u03bf\u03bc\u03ad\u03bd\u03b1 \u03b4\u03b5\u03bd \u03c5\u03c0\u03bf\u03c3\u03c4\u03b7\u03c1\u03af\u03b6\u03bf\u03c5\u03bd \u03c5\u03c0\u03b5\u03c1\u03bf\u03c7\u03ae \u03ae \u03c5\u03c3\u03c4\u03ad\u03c1\u03b7\u03c3\u03b7 \u03c4\u03c9\u03bd ACEI \u03ae \u03c4\u03c9\u03bd \u03b1\u03bd\u03b1\u03c3\u03c4\u03bf\u03bb\u03ad\u03c9\u03bd \u03c4\u03c9\u03bd \u03c5\u03c0\u03bf\u03b4\u03bf\u03c7\u03ad\u03c9\u03bd Ang II \u03c3\u03b5 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 \u03bc\u03cc\u03bb\u03c5\u03bd\u03c3\u03b7 \u03b1\u03c0\u03cc \u03c4\u03bf\u03bd COVID-19.<\/li>\n
  4. \u03a3\u03b5 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 \u03bc\u03cc\u03bb\u03c5\u03bd\u03c3\u03b7 \u03bc\u03b5 COVID-19 \u03ba\u03b1\u03b9 \u03c3\u03bf\u03b2\u03b1\u03c1\u03ae \u03c3\u03c5\u03bc\u03c0\u03c4\u03c9\u03bc\u03b1\u03c4\u03bf\u03bb\u03bf\u03b3\u03af\u03b1, \u03c4\u03b1 \u03c6\u03ac\u03c1\u03bc\u03b1\u03ba\u03b1 \u03c0\u03bf\u03c5 \u03bc\u03c0\u03bb\u03bf\u03ba\u03ac\u03c1\u03bf\u03c5\u03bd \u03c4\u03bf \u03a3\u03a1\u0391 \u03c0\u03c1\u03ad\u03c0\u03b5\u03b9 \u03bd\u03b1 \u03c7\u03c1\u03b7\u03c3\u03b9\u03bc\u03bf\u03c0\u03bf\u03b9\u03bf\u03cd\u03bd\u03c4\u03b1\u03b9 \u03ae \u03bd\u03b1 \u03b4\u03b9\u03b1\u03ba\u03cc\u03c0\u03c4\u03bf\u03bd\u03c4\u03b1\u03b9 \u03c3\u03b5 \u03b5\u03be\u03b1\u03c4\u03bf\u03bc\u03b9\u03ba\u03b5\u03c5\u03bc\u03ad\u03bd\u03b7 \u03b2\u03ac\u03c3\u03b7 \u03bb\u03b1\u03bc\u03b2\u03ac\u03bd\u03bf\u03bd\u03c4\u03b1\u03c2 \u03c5\u03c0\u03cc\u03c8\u03b9\u03bd \u03c4\u03b9\u03c2 \u03b1\u03bd\u03c4\u03af\u03c3\u03c4\u03bf\u03b9\u03c7\u03b5\u03c2 \u03ba\u03b1\u03c4\u03b5\u03c5\u03b8\u03c5\u03bd\u03c4\u03ae\u03c1\u03b9\u03b5\u03c2 \u03bf\u03b4\u03b7\u03b3\u03af\u03b5\u03c2.<\/li>\n
  5. \u03a0\u03b5\u03c1\u03b1\u03b9\u03c4\u03ad\u03c1\u03c9 \u03ad\u03c1\u03b5\u03c5\u03bd\u03b1 \u03b3\u03b9\u03b1 \u03c4\u03b7\u03bd \u03b5\u03c0\u03af\u03b4\u03c1\u03b1\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03c5\u03c0\u03ad\u03c1\u03c4\u03b1\u03c3\u03b7\u03c2 \u03b1\u03bb\u03bb\u03ac \u03ba\u03b1\u03b9 \u03c4\u03c9\u03bd \u03b1\u03bd\u03c4\u03b9\u03c5\u03c0\u03b5\u03c1\u03c4\u03b1\u03c3\u03b9\u03ba\u03ce\u03bd \u03c6\u03b1\u03c1\u03bc\u03ac\u03ba\u03c9\u03bd \u03c3\u03c4\u03b7 \u03ad\u03ba\u03b2\u03b1\u03c3\u03b7 \u03c4\u03c9\u03bd \u03b1\u03c3\u03b8\u03b5\u03bd\u03ce\u03bd \u03bc\u03b5 \u03bc\u03cc\u03bb\u03c5\u03bd\u03c3\u03b7 \u03b1\u03c0\u03cc \u03ba\u03bf\u03c1\u03bf\u03bd\u03bf\u03ca\u03cc COVID-19 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b1\u03bd\u03b1\u03b3\u03ba\u03b1\u03af\u03b1.<\/li>\n<\/ol>\n

     <\/p>\n

    \u0392\u0399\u0392\u039b\u0399\u039f\u0393\u03a1\u0391\u03a6\u0399\u0391<\/strong><\/p>\n

      \n
    1. Fisher D and Heymann D. Q&A: The novel coronavirus outbreak causing COVID19. BMC medicine. 2020;18:57.<\/li>\n
    2. Fei Zhou*, Ting Yu*, et al. Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study .Lancet,March 9, 2020 (https:doi.org\/10.1016\/S0140-6736 (20) 30566-3<\/li>\n
    3. Turner, A. J., Hiscox, J. A. & Hooper, N. M. ACE2: from vasopeptidase to SARS virus receptor. Trends Pharmacol. Sci. 25, 291\u2013294 (2004).<\/li>\n
    4. Li W, et al. Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirus. Nature. 2003;426:450-4.<\/li>\n
    5. Romero CA, Orias M and Weir MR. Novel RAAS agonists and antagonists: clinical applications and controversies. Nature reviews Endocrinology. 2015;11:242-52.<\/li>\n
    6. Zhang H, Penninger JM, Li Y, Zhong N and Slutsky AS. Angiotensin-converting enzyme 2 (ACE2) as a SARS-CoV-2 receptor: molecular mechanisms and potential therapeutic target. Intensive Care Medicine. 2020<\/li>\n
    7. Soler MJ, et al. Pharmacologic modulation of ACE2 expression. Current hypertension reports. 2008;10:410-4.<\/li>\n
    8. 2018 ESC\/ESH Guidelines for the management of arterial hypertension: The Task Force for the management of arterial hypertension of the European Society of Cardiology and the European Society of Hypertension: The Task Force for the management of arterial hypertension of the European Society of Cardiology and the European Society of Hypertension. Journal of hypertension. 2018;36:1953-2041.<\/li>\n
    9. Hamming I, et al. Differential regulation of renal angiotensin-converting enzyme (ACE) and ACE2 during ACE inhibition and dietary sodium restriction in healthy rats. Experimental physiology. 2008;93:631-<\/li>\n
    10. Gurwitz D. Angiotensin receptor blockers as tentative SARS-CoV-2 therapeutics. Drug development research. 2020.<\/li>\n
    11. Furuhashi M, Moniwa N, Mita T, Fuseya T, Ishimura S, Ohno K, Shibata S, Tanaka M, Watanabe Y, Akasaka H, Ohnishi H, Yoshida H, Takizawa H, Saitoh S, Ura N, Shimamoto K and Miura T. Urinary angiotensin-converting enzyme 2 in hypertensive patients may be increased by olmesartan, an angiotensin II receptor blocker. American journal of hypertension. 2015;28:15-21.<\/li>\n
    12. https:\/\/www.eshonline.org\/spotlights\/esh-statement-on-covid-19\/<\/li>\n<\/ol>\n
      \"\"

      \u039f \u03ba\u03b1\u03b8\u03b7\u03b3\u03b7\u03c4\u03ae\u03c2 \u039a\u03c9\u03bd. \u03a4\u03c3\u03b9\u03bf\u03cd\u03c6\u03b7\u03c2<\/p><\/div>\n

      \u039a\u03a9\u039d\u03a3\u03a4\u0391\u039d\u03a4\u0399\u039d\u039f\u03a3\u00a0\u03a4\u03a3\u0399\u039f\u03a5\u03a6\u0397\u03a3<\/strong><\/p>\n

      \u039a\u0391\u0398\u0397\u0393\u0397\u03a4\u0397\u03a3 \u039a\u0391\u03a1\u0394\u0399\u039f\u039b\u039f\u0393\u0399\u0391\u03a3 \u0395\u039a\u03a0\u0391<\/p>\n

      \u03a0\u03a1\u039f\u0395\u0394\u03a1\u039f\u03a3 \u0395\u039b\u039b\u0397\u039d\u0399\u039a\u0397\u03a3 \u039a\u0391\u03a1\u0394\u0399\u039f\u039b\u039f\u0393\u0399\u039a\u0397\u03a3 \u0395\u03a4\u0391\u0399\u03a1\u0395\u0399\u0391\u03a3 (2017-18)<\/p>\n

      PRESIDENT OF EUROPEAN SOCIETY OF CARDIOLOGY (2018-19)<\/p>\n

      www.ktsioufis.com<\/p>\n","protected":false},"excerpt":{"rendered":"

      \u0397 \u03bb\u03bf\u03c3\u03b1\u03c1\u03c4\u03ac\u03bd\u03b7 \u03ae\u03c4\u03b1\u03bd \u03bf \u03c0\u03c1\u03ce\u03c4\u03bf\u03c2 \u03bc\u03b7 \u03c0\u03b5\u03c0\u03c4\u03b9\u03b4\u03b9\u03ba\u03cc\u03c2 \u03b1\u03bd\u03c4\u03b1\u03b3\u03c9\u03bd\u03b9\u03c3\u03c4\u03ae\u03c2 \u03c4\u03c9\u03bd \u03c5\u03c0\u03bf\u03b4\u03bf\u03c7\u03ad\u03c9\u03bd \u03c4\u03b7\u03c2 \u03b1\u03b3\u03b3\u03b5\u03b9\u03bf\u03c4\u03b5\u03bd\u03c3\u03af\u03bd\u03b7\u03c2 II \u03c0\u03bf\u03c5 \u03c7\u03c1\u03b7\u03c3\u03b9\u03bc\u03bf\u03c0\u03bf\u03b9\u03ae\u03b8\u03b7\u03ba\u03b5 \u03c9\u03c2 \u03b1\u03bd\u03c4\u03b9\u03c5\u03c0\u03b5\u03c1\u03c4\u03b1\u03c3\u03b9\u03ba\u03cc \u03c6\u03ac\u03c1\u03bc\u03b1\u03ba\u03bf. \u0388\u03ba\u03c4\u03bf\u03c4\u03b5 \u03ad\u03c7\u03bf\u03c5\u03bd \u03b5\u03b9\u03c3\u03b1\u03c7\u03b8\u03b5\u03af \u03ba\u03b1\u03b9 \u03ba\u03b1\u03c4\u03b1\u03c7\u03c9\u03c1\u03b7\u03b8\u03b5\u03af \u03c0\u03bf\u03bb\u03bb\u03ac \u03c6\u03ac\u03c1\u03bc\u03b1\u03ba\u03b1 \u03b2\u03b1\u03c3\u03b9\u03c3\u03bc\u03ad\u03bd\u03b1 \u03c3\u03b5 \u03b1\u03c5\u03c4\u03ae \u03c4\u03b7\u03bd \u03b1\u03c1\u03c7\u03ae. \u0397 \u03b4\u03b9\u03c6\u03b1\u03b9\u03bd\u03c5\u03bb\u03b9\u03ba\u03ae \u03b4\u03bf\u03bc\u03ae \u03b5\u03af\u03bd\u03b1\u03b9 \u03c7\u03b1\u03c1\u03b1\u03ba\u03c4\u03b7\u03c1\u03b9\u03c3\u03c4\u03b9\u03ba\u03ae \u03c4\u03c9\u03bd \u03c0\u03b5\u03c1\u03b9\u03c3\u03c3\u03bf\u03c4\u03ad\u03c1\u03c9\u03bd \u03b1\u03bb\u03bb\u03ac \u03cc\u03c7\u03b9 \u03cc\u03bb\u03c9\u03bd \u03c4\u03c9\u03bd \u03b1\u03bd\u03c4\u03b1\u03b3\u03c9\u03bd\u03b9\u03c3\u03c4\u03ce\u03bd \u03c4\u03c9\u03bd \u03c5\u03c0\u03bf\u03b4\u03bf\u03c7\u03ad\u03c9\u03bd \u03c4\u03b7\u03c2 \u03b1\u03b3\u03b3\u03b5\u03b9\u03bf\u03c4\u03b5\u03bd\u03c3\u03af\u03bd\u03b7\u03c2 \u0399\u0399 \u03ba\u03b1\u03b9 \u03c0\u03bf\u03bb\u03bb\u03bf\u03af \u03b5\u03be \u03b1\u03c5\u03c4\u03ce\u03bd \u03c0\u03b5\u03c1\u03b9\u03ad\u03c7\u03bf\u03c5\u03bd \u03ad\u03bd\u03b1 \u03b9\u03bc\u03b9\u03b4\u03b1\u03b6\u03bf\u03bb\u03b9\u03ba\u03cc \u03c3\u03c4\u03bf\u03b9\u03c7\u03b5\u03af\u03bf … <\/p>\n

      \u03a3\u03c5\u03bd\u03ad\u03c7\u03b5\u03b9\u03b1 \u03b1\u03bd\u03ac\u03b3\u03bd\u03c9\u03c3\u03b7\u03c2<\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[85,41],"tags":[90],"class_list":["post-14264","post","type-post","status-publish","format-standard","hentry","category-85","category-41","tag-90","item-wrap"],"_links":{"self":[{"href":"https:\/\/evaggelatos.com\/index.php?rest_route=\/wp\/v2\/posts\/14264","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/evaggelatos.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/evaggelatos.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/evaggelatos.com\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/evaggelatos.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=14264"}],"version-history":[{"count":3,"href":"https:\/\/evaggelatos.com\/index.php?rest_route=\/wp\/v2\/posts\/14264\/revisions"}],"predecessor-version":[{"id":14268,"href":"https:\/\/evaggelatos.com\/index.php?rest_route=\/wp\/v2\/posts\/14264\/revisions\/14268"}],"wp:attachment":[{"href":"https:\/\/evaggelatos.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=14264"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/evaggelatos.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=14264"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/evaggelatos.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=14264"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}