{"id":23495,"date":"2021-11-05T06:37:28","date_gmt":"2021-11-05T06:37:28","guid":{"rendered":"https:\/\/evaggelatos.com\/?p=23495"},"modified":"2021-11-05T06:46:10","modified_gmt":"2021-11-05T06:46:10","slug":"%ce%b7-fenofibrate-%cf%86%ce%b1%ce%af%ce%bd%ce%b5%cf%84%ce%b1%ce%b9-%ce%bd%ce%b1-%ce%bc%ce%b5%ce%b9%cf%8e%ce%bd%ce%b5%ce%b9-%cf%84%ce%b7%ce%bd-%ce%b1-%ce%ba%ce%b1%ce%b9-%ce%b2-%ce%bc%ce%b5%cf%84%ce%ac","status":"publish","type":"post","link":"https:\/\/evaggelatos.com\/?p=23495","title":{"rendered":"\u0397 fenofibrate \u03c6\u03b1\u03af\u03bd\u03b5\u03c4\u03b1\u03b9 \u03bd\u03b1 \u03bc\u03b5\u03b9\u03ce\u03bd\u03b5\u03b9 \u03c4\u03b7\u03bd \u0391 \u03ba\u03b1\u03b9 \u0392 \u03bc\u03b5\u03c4\u03ac\u03bb\u03bb\u03b1\u03be\u03b7 \u03c4\u03bf\u03c5 Covid-19"},"content":{"rendered":"<header class=\"c-post-single__header c-post-single__header--no-image\">\n<div class=\"grid-container\">\n<div class=\"grid-x grid-padding-x align-center\">\n<div class=\"cell xlarge-10 xxlarge-9\">\n<h1 class=\"c-post-single__title\">Study finds fenofibrate\u2019s ability to reduce Covid-19 infection<\/h1>\n<div class=\"c-post-single__header-meta-after\"><span class=\"c-post-single__header-publish-date\"> 09 Aug 2021<\/span><\/div>\n<p class=\"c-post-single__standfirst\">Fenofibrate[1] also demonstrated efficacy against the newly emergent alpha and beta variants of SARS-CoV-2 in the study.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/header>\n<div class=\"grid-container grid-container--post-single\">\n<div class=\"grid-x grid-padding-x align-center\">\n<div class=\"cell large-3 xlarge-2\">\n<aside class=\"c-post-single__sidebar-left\">\n<aside class=\"c-post-share\">\n<section class=\"c-post-share__social\">\n<h4 class=\"c-post-share__social-title\">Share Article<\/h4>\n<\/section>\n<\/aside>\n<\/aside>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"cell large-3 xlarge-2\">\n<aside class=\"c-post-single__sidebar-left\">\n<aside class=\"c-post-share\">\n<section class=\"c-post-share__social\">\n<div class=\"c-post-share__social-links\"><\/div>\n<\/section>\n<\/aside>\n<\/aside>\n<\/div>\n<div class=\"cell smedium-10 large-9 xlarge-7\">\n<div class=\"c-post-single__content-column\">\n<div class=\"c-post-single__content c-post-typography\">\n<p>A research team led by the University of Birmingham and Keele University in the UK has found that a licensed oral drug, fenofibrate, and its active form, fenofibric acid, can substantially reduce SARS-CoV-2 infection in human cells in the laboratory.<\/p>\n<p>Approved in various countries, fenofibrate is being used for the treatment of conditions such as increased cholesterol and fatty substance levels in the blood.<\/p>\n<p>Fenofibrate decreased Covid-19 infection by up to 70% at concentrations that are safe and attainable with its standard clinical dose, the University of Birmingham noted.<\/p>\n<p>Led by the San Raffaele Scientific Institute in Italy, the research was conducted in partnership with the University of Copenhagen in Denmark and the University of Liverpool, UK.<\/p>\n<p>In the study, researchers analysed a panel of presently licensed drugs, including fenofibrate, to detect candidates that can interrupt angiotensin-converting enzyme 2 (ACE2) and Spike interactions.<\/p>\n<p>Fenofibrate was selected and assessed for efficacy in reducing infection in cells in the laboratory with the use of the SARS-CoV-2 original strains isolated last year.<\/p>\n<p>Furthermore, additional unpublished findings showed that <strong>the drug worked against the newly emergent SARS-CoV-2 variants such as the Alpha and Beta variants.<\/strong><\/p>\n<p>The university added that further research is underway to analyse the drug\u2019s efficacy against the Delta variant.<\/p>\n<p>\u03a0\u03b7\u03b3\u03ae:https:\/\/www.clinicaltrialsarena.com\/news\/study-fenofibrate-covid-infection\/<\/p>\n<p>[1]\u0397 \u03c6\u03b1\u03b9\u03bd\u03bf\u03c6\u03b9\u03b2\u03c1\u03ac\u03c4\u03b7 (fenofibrate) \u03b5\u03af\u03bd\u03b1\u03b9 \u03ad\u03bd\u03b1 \u03c0\u03b1\u03c1\u03ac\u03b3\u03c9\u03b3\u03bf \u03c4\u03bf\u03c5 \u03b9\u03bd\u03b9\u03ba\u03bf\u03cd \u03bf\u03be\u03ad\u03bf\u03c2, \u03c4\u03bf\u03c5 \u03bf\u03c0\u03bf\u03af\u03bf\u03c5 \u03b7 \u03b4\u03c1\u03ac\u03c3\u03b7 \u03bd\u03b1 \u03bc\u03b5\u03c4\u03b1\u03b2\u03ac\u03bb\u03bb\u03b5\u03b9 \u03c4\u03b1 \u03b5\u03c0\u03af\u03c0\u03b5\u03b4\u03b1 \u03c4\u03c9\u03bd \u03bb\u03b9\u03c0\u03b9\u03b4\u03af\u03c9\u03bd \u03c3\u03c4\u03bf\u03bd \u03ac\u03bd\u03b8\u03c1\u03c9\u03c0\u03bf \u03bc\u03b5\u03c3\u03bf\u03bb\u03b1\u03b2\u03b5\u03af\u03c4\u03b1\u03b9 \u03bc\u03b5 \u03b5\u03bd\u03b5\u03c1\u03b3\u03bf\u03c0\u03bf\u03af\u03b7\u03c3\u03b7 \u03c4\u03bf\u03c5 \u03c5\u03c0\u03bf\u03b4\u03bf\u03c7\u03ad\u03b1 PPAR\u03b1. \u039c\u03ad\u03c3\u03c9 \u03c4\u03b7\u03c2 \u03b5\u03bd\u03b5\u03c1\u03b3\u03bf\u03c0\u03bf\u03af\u03b7\u03c3\u03b7\u03c2 \u03c4\u03bf\u03c5 PPAR\u03b1, \u03b7 \u03c6\u03b1\u03b9\u03bd\u03bf\u03c6\u03b9\u03b2\u03c1\u03ac\u03c4\u03b7 \u03b1\u03c5\u03be\u03ac\u03bd\u03b5\u03b9 \u03c4\u03b7 \u03bb\u03b9\u03c0\u03cc\u03bb\u03c5\u03c3\u03b7 \u03ba\u03b1\u03b9 \u03c4\u03b7\u03bd \u03b1\u03c0\u03bf\u03b2\u03bf\u03bb\u03ae \u03c4\u03c9\u03bd \u03b1\u03b8\u03b7\u03c1\u03bf\u03b3\u03cc\u03bd\u03c9\u03bd \u03c0\u03bb\u03bf\u03cd\u03c3\u03b9\u03c9\u03bd \u03c3\u03b5 \u03c4\u03c1\u03b9\u03b3\u03bb\u03c5\u03ba\u03b5\u03c1\u03af\u03b4\u03b9\u03b1 \u03c3\u03c9\u03bc\u03b1\u03c4\u03af\u03c9\u03bd \u03b1\u03c0\u03cc \u03c4\u03bf \u03c0\u03bb\u03ac\u03c3\u03bc\u03b1 \u03b5\u03bd\u03b5\u03c1\u03b3\u03bf\u03c0\u03bf\u03b9\u03ce\u03bd\u03c4\u03b1\u03c2 \u03c4\u03b7 \u03bb\u03b9\u03c0\u03bf\u03c0\u03c1\u03c9\u03c4\u03b5\u03ca\u03bd\u03b9\u03ba\u03ae \u03bb\u03b9\u03c0\u03ac\u03c3\u03b7 \u03ba\u03b1\u03b9 \u03bc\u03b5\u03b9\u03ce\u03bd\u03bf\u03bd\u03c4\u03b1\u03c2 \u03c4\u03b7\u03bd \u03c0\u03b1\u03c1\u03b1\u03b3\u03c9\u03b3\u03ae \u03c4\u03b7\u03c2 \u03b1\u03c0\u03bf\u03c0\u03c1\u03c9\u03c4\u03b5\u0390\u03bd\u03b7\u03c2 C-III.<\/p>\n<div id=\"selectionBlock0.8709496910661807\">\n<div><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Study finds fenofibrate\u2019s ability to reduce Covid-19 infection 09 Aug 2021 Fenofibrate[1] also demonstrated efficacy against the newly emergent alpha and beta variants of SARS-CoV-2 in the study. Share Article A research team led by the University of Birmingham and Keele University in the UK has found that a licensed oral drug, fenofibrate, and its &hellip; <\/p>\n<p><a class=\"more-link btn\" href=\"https:\/\/evaggelatos.com\/?p=23495\">\u03a3\u03c5\u03bd\u03ad\u03c7\u03b5\u03b9\u03b1 \u03b1\u03bd\u03ac\u03b3\u03bd\u03c9\u03c3\u03b7\u03c2<\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[85],"tags":[143],"class_list":["post-23495","post","type-post","status-publish","format-standard","hentry","category-85","tag-143","item-wrap"],"_links":{"self":[{"href":"https:\/\/evaggelatos.com\/index.php?rest_route=\/wp\/v2\/posts\/23495","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/evaggelatos.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/evaggelatos.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/evaggelatos.com\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/evaggelatos.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=23495"}],"version-history":[{"count":4,"href":"https:\/\/evaggelatos.com\/index.php?rest_route=\/wp\/v2\/posts\/23495\/revisions"}],"predecessor-version":[{"id":23499,"href":"https:\/\/evaggelatos.com\/index.php?rest_route=\/wp\/v2\/posts\/23495\/revisions\/23499"}],"wp:attachment":[{"href":"https:\/\/evaggelatos.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=23495"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/evaggelatos.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=23495"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/evaggelatos.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=23495"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}