{"id":26419,"date":"2022-07-06T13:43:26","date_gmt":"2022-07-06T13:43:26","guid":{"rendered":"https:\/\/evaggelatos.com\/?p=26419"},"modified":"2022-07-07T07:20:03","modified_gmt":"2022-07-07T07:20:03","slug":"26419","status":"publish","type":"post","link":"https:\/\/evaggelatos.com\/?p=26419","title":{"rendered":"\u0397 \u03b1\u03ba\u03af\u03b4\u03b1 \u03c4\u03bf\u03c5 SARS-CoV-2 \u03b5\u03c0\u03b9\u03bc\u03ad\u03bd\u03b5\u03b9 \u03b3\u03b9\u03b1 \u03bc\u03ae\u03bd\u03b5\u03c2 \u03ba\u03b1\u03b9 \u03c3\u03c7\u03b5\u03c4\u03af\u03b6\u03b5\u03c4\u03b1\u03b9 \u03bc\u03b5 \u03c4\u03b1 \u03bc\u03b5\u03c4\u03b1-\u03bf\u03be\u03ad\u03b1 \u03b5\u03c0\u03b1\u03ba\u03cc\u03bb\u03bf\u03c5\u03b8\u03b1 \u03c4\u03bf\u03c5 \u03b9\u03bf\u03cd"},"content":{"rendered":"<div id=\"region-content\" class=\"grid-28 suffix-1 prefix-1 region region-content\">\n<div class=\"region-inner region-content-inner\">\n<div id=\"block-system-main\" class=\"block block-system block-main block-system-main odd block-without-title\">\n<div class=\"block-inner clearfix\">\n<div class=\"content clearfix\">\n<div class=\"panel-display panels-960-layout jcore-2col-layout\">\n<div class=\"panel-row-wrapper clearfix\">\n<div class=\"main-content-wrapper grid-17 suffix-1 alpha\">\n<div class=\"panel-panel panel-region-content\">\n<div class=\"inside\">\n<div class=\"panel-pane pane-highwire-article-citation\">\n<div class=\"pane-content\">\n<div id=\"node527623--2870248528\" class=\"highwire-article-citation highwire-citation-type-highwire-article node527623\" data-node-nid=\"527623\" data-pisa=\"medrxiv;2022.06.14.22276401v1\" data-pisa-master=\"medrxiv;2022.06.14.22276401\" data-apath=\"\/medrxiv\/early\/2022\/06\/16\/2022.06.14.22276401.atom\" data-hw-author-tooltip-instance=\"\">\n<div class=\"highwire-cite highwire-cite-highwire-article highwire-citation-medrxiv-article-top clearfix has-author-tooltip\">\n<h1 id=\"page-title\" class=\"highwire-cite-title\">\u0397 \u03b5\u03c0\u03af\u03bc\u03bf\u03bd\u03b7 \u03ba\u03c5\u03ba\u03bb\u03bf\u03c6\u03bf\u03c1\u03bf\u03cd\u03c3\u03b1 \u03b1\u03ba\u03af\u03b4\u03b1 SARS-CoV-2 \u03c3\u03c7\u03b5\u03c4\u03af\u03b6\u03b5\u03c4\u03b1\u03b9 \u03bc\u03b5 \u03c4\u03b1 \u03bc\u03b5\u03c4\u03b1-\u03bf\u03be\u03ad\u03b1 \u03b5\u03c0\u03b1\u03ba\u03cc\u03bb\u03bf\u03c5\u03b8\u03b1 \u03c4\u03bf\u03c5 COVID-19<\/h1>\n<div class=\"highwire-cite-authors\"><span class=\"highwire-citation-authors\"><span class=\"highwire-citation-author first hw-author-orcid-logo-wrapper has-tooltip hasTooltip\" data-delta=\"0\" data-hasqtip=\"1\" aria-describedby=\"qtip-1\"><a class=\"hw-author-orcid-logo link-icon-only link-icon\" href=\"http:\/\/orcid.org\/0000-0001-8825-0335\" target=\"_blank\" rel=\"noopener\"> <span class=\"title element-invisible\">\u03a0\u03c1\u03bf\u03b2\u03bf\u03bb\u03ae \u03a0\u03c1\u03bf\u03c6\u03af\u03bb ORCID <\/span><\/a><span class=\"nlm-given-names\">Zoe <\/span> <span class=\"nlm-surname\">Swank <\/span><\/span>, <span class=\"highwire-citation-author hw-author-orcid-logo-wrapper has-tooltip hasTooltip\" data-delta=\"1\" data-hasqtip=\"0\"><a class=\"hw-author-orcid-logo link-icon-only link-icon\" href=\"http:\/\/orcid.org\/0000-0002-6881-5455\" target=\"_blank\" rel=\"noopener\"> <span class=\"title element-invisible\">\u03a0\u03c1\u03bf\u03b2\u03bf\u03bb\u03ae \u03a0\u03c1\u03bf\u03c6\u03af\u03bb ORCID <\/span><\/a><span class=\"nlm-given-names\">Yasmeen <\/span> <span class=\"nlm-surname\">Senussi <\/span><\/span>, <span class=\"highwire-citation-author has-tooltip hasTooltip\" data-delta=\"2\" data-hasqtip=\"2\"><span class=\"nlm-given-names\">Galit <\/span> <span class=\"nlm-surname\">Alter <\/span><\/span>, <span class=\"highwire-citation-author hw-author-orcid-logo-wrapper has-tooltip hasTooltip\" data-delta=\"3\" data-hasqtip=\"3\" aria-describedby=\"qtip-3\"><a class=\"hw-author-orcid-logo link-icon-only link-icon\" href=\"http:\/\/orcid.org\/0000-0002-5524-7348\" target=\"_blank\" rel=\"noopener\"> <span class=\"title element-invisible\">\u03a0\u03c1\u03bf\u03b2\u03bf\u03bb\u03ae \u03a0\u03c1\u03bf\u03c6\u03af\u03bb ORCID <\/span><\/a><span class=\"nlm-given-names\">David R. <\/span> <span class=\"nlm-surname\">Walt <\/span><\/span><\/span><\/div>\n<div class=\"highwire-cite-metadata\">\n<p><span class=\"highwire-cite-metadata-doi highwire-cite-metadata\"><span class=\"label\">doi: <\/span>https:\/\/doi.org\/10.1101\/2022.06.14.22276401 <\/span><\/p>\n<div class=\"pub_jnl\"><a href=\"https:\/\/www.medrxiv.org\/content\/what-unrefereed-preprint\" target=\"_blank\" rel=\"noopener\">\u0391\u03c5\u03c4\u03cc \u03c4\u03bf \u03ac\u03c1\u03b8\u03c1\u03bf \u03b5\u03af\u03bd\u03b1\u03b9 \u03c0\u03c1\u03bf\u03b5\u03ba\u03c4\u03cd\u03c0\u03c9\u03c3\u03b7 \u03ba\u03b1\u03b9 \u03b4\u03b5\u03bd \u03ad\u03c7\u03b5\u03b9 \u03b1\u03be\u03b9\u03bf\u03bb\u03bf\u03b3\u03b7\u03b8\u03b5\u03af \u03b1\u03c0\u03cc \u03bf\u03bc\u03bf\u03c4\u03af\u03bc\u03bf\u03c5\u03c2 [\u03c4\u03b9 \u03c3\u03b7\u03bc\u03b1\u03af\u03bd\u03b5\u03b9 \u03b1\u03c5\u03c4\u03cc;]. \u0391\u03bd\u03b1\u03c6\u03ad\u03c1\u03b5\u03b9 \u03bd\u03ad\u03b1 \u03b9\u03b1\u03c4\u03c1\u03b9\u03ba\u03ae \u03ad\u03c1\u03b5\u03c5\u03bd\u03b1 \u03c0\u03bf\u03c5 \u03b4\u03b5\u03bd \u03ad\u03c7\u03b5\u03b9 \u03b1\u03ba\u03cc\u03bc\u03b7 \u03b1\u03be\u03b9\u03bf\u03bb\u03bf\u03b3\u03b7\u03b8\u03b5\u03af \u03ba\u03b1\u03b9 \u03b3\u03b9&#8217; \u03b1\u03c5\u03c4\u03cc \u03b4\u03b5\u03bd \u03b8\u03b1 \u03c0\u03c1\u03ad\u03c0\u03b5\u03b9 <em>\u03bd\u03b1 <\/em>\u03c7\u03c1\u03b7\u03c3\u03b9\u03bc\u03bf\u03c0\u03bf\u03b9\u03b5\u03af\u03c4\u03b1\u03b9 \u03b3\u03b9\u03b1 \u03c4\u03b7\u03bd \u03ba\u03b1\u03b8\u03bf\u03b4\u03ae\u03b3\u03b7\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae\u03c2 \u03c0\u03c1\u03b1\u03ba\u03c4\u03b9\u03ba\u03ae\u03c2. <\/a><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"panel-separator\"><\/div>\n<div class=\"panel-pane pane-highwire-panel-tabs pane-panels-ajax-tab-tabs\"><\/div>\n<\/div>\n<div class=\"panel-pane pane-highwire-panel-tabs-container\">\n<div class=\"pane-content\">\n<div id=\"panels-ajax-tab-container-highwire_article_tabs\" class=\"panels-ajax-tab-container\" data-panels-ajax-tab-preloaded=\"article_tab_full_text\">\n<div class=\"panels-ajax-tab-wrap-article_tab_full_text\">\n<div class=\"panel-display panel-1col clearfix\">\n<div class=\"panel-panel panel-col\">\n<div>\n<div class=\"panel-pane pane-highwire-markup\">\n<div class=\"pane-content\">\n<div class=\"highwire-markup\">\n<div class=\"content-block-markup\" data-highwire-cite-ref-tooltip-instance=\"highwire_reflinks_tooltip\">\n<div class=\"article fulltext-view \">\n<div id=\"abstract-1\" class=\"section abstract\">\n<h2 class=\"\">\u0391\u03c6\u03b7\u03c1\u03b7\u03bc\u03ad\u03bd\u03b7<\/h2>\n<p id=\"p-2\">\u0397 \u03b4\u03b9\u03ac\u03b3\u03bd\u03c9\u03c3\u03b7 \u03ba\u03b1\u03b9 \u03b7 \u03b4\u03b9\u03b1\u03c7\u03b5\u03af\u03c1\u03b9\u03c3\u03b7 \u03c4\u03c9\u03bd \u03bc\u03b5\u03c4\u03b1-\u03bf\u03be\u03ad\u03c9\u03bd \u03b5\u03c0\u03b1\u03ba\u03cc\u03bb\u03bf\u03c5\u03b8\u03c9\u03bd \u03c4\u03bf\u03c5 COVID-19 (PASC) \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03b5\u03af \u03bc\u03b9\u03b1 \u03c3\u03c5\u03bd\u03b5\u03c7\u03ae \u03b9\u03b1\u03c4\u03c1\u03b9\u03ba\u03ae \u03c0\u03c1\u03cc\u03ba\u03bb\u03b7\u03c3\u03b7. \u039f \u03b5\u03bd\u03c4\u03bf\u03c0\u03b9\u03c3\u03bc\u03cc\u03c2 \u03b2\u03b9\u03bf\u03b4\u03b5\u03b9\u03ba\u03c4\u03ce\u03bd \u03c0\u03bf\u03c5 \u03c3\u03c7\u03b5\u03c4\u03af\u03b6\u03bf\u03bd\u03c4\u03b1\u03b9 \u03bc\u03b5 \u03c4\u03bf PASC \u03b8\u03b1 \u03b2\u03b5\u03bb\u03c4\u03af\u03c9\u03bd\u03b5 \u03c0\u03ac\u03c1\u03b1 \u03c0\u03bf\u03bb\u03cd \u03c4\u03b7\u03bd \u03c4\u03b1\u03be\u03b9\u03bd\u03cc\u03bc\u03b7\u03c3\u03b7 \u03c4\u03c9\u03bd \u03b1\u03c3\u03b8\u03b5\u03bd\u03ce\u03bd \u03bc\u03b5 PASC \u03ba\u03b1\u03b9 \u03b8\u03b1 \u03c0\u03b1\u03c1\u03b5\u03af\u03c7\u03b5 \u03c4\u03b1 \u03bc\u03ad\u03c3\u03b1 \u03b3\u03b9\u03b1 \u03c4\u03b7\u03bd \u03b1\u03be\u03b9\u03bf\u03bb\u03cc\u03b3\u03b7\u03c3\u03b7 \u03c4\u03c9\u03bd \u03c3\u03c4\u03c1\u03b1\u03c4\u03b7\u03b3\u03b9\u03ba\u03ce\u03bd \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1\u03c2. \u0391\u03bd\u03b1\u03bb\u03cd\u03c3\u03b1\u03bc\u03b5 \u03b4\u03b5\u03af\u03b3\u03bc\u03b1\u03c4\u03b1 \u03c0\u03bb\u03ac\u03c3\u03bc\u03b1\u03c4\u03bf\u03c2 \u03c0\u03bf\u03c5 \u03c3\u03c5\u03bb\u03bb\u03ad\u03c7\u03b8\u03b7\u03ba\u03b1\u03bd \u03b1\u03c0\u03cc \u03bc\u03b9\u03b1 \u03ba\u03bf\u03cc\u03c1\u03c4\u03b7 \u03b1\u03c3\u03b8\u03b5\u03bd\u03ce\u03bd \u03bc\u03b5 PASC \u03ba\u03b1\u03b9 COVID-19 (n = 63) \u03b3\u03b9\u03b1 \u03bd\u03b1 \u03c0\u03bf\u03c3\u03bf\u03c4\u03b9\u03ba\u03bf\u03c0\u03bf\u03b9\u03ae\u03c3\u03bf\u03c5\u03bc\u03b5 \u03c4\u03b1 \u03ba\u03c5\u03ba\u03bb\u03bf\u03c6\u03bf\u03c1\u03bf\u03cd\u03bd\u03c4\u03b1 \u03b9\u03b9\u03ba\u03ac \u03b1\u03bd\u03c4\u03b9\u03b3\u03cc\u03bd\u03b1 \u03ba\u03b1\u03b9 \u03c4\u03bf\u03c5\u03c2 \u03c6\u03bb\u03b5\u03b3\u03bc\u03bf\u03bd\u03ce\u03b4\u03b5\u03b9\u03c2 \u03b4\u03b5\u03af\u03ba\u03c4\u03b5\u03c2. \u0395\u03bd\u03c4\u03c5\u03c0\u03c9\u03c3\u03b9\u03b1\u03ba\u03ac, \u03b1\u03bd\u03b9\u03c7\u03bd\u03b5\u03cd\u03bf\u03c5\u03bc\u03b5 \u03b1\u03bd\u03c4\u03b9\u03b3\u03cc\u03bd\u03bf \u03b1\u03ba\u03af\u03b4\u03b1\u03c2 SARS-CoV-2 \u03c3\u03c4\u03b7\u03bd \u03c0\u03bb\u03b5\u03b9\u03bf\u03bd\u03cc\u03c4\u03b7\u03c4\u03b1 \u03c4\u03c9\u03bd \u03b1\u03c3\u03b8\u03b5\u03bd\u03ce\u03bd \u03bc\u03b5 PASC \u03ad\u03c9\u03c2 \u03ba\u03b1\u03b9 12 \u03bc\u03ae\u03bd\u03b5\u03c2 \u03bc\u03b5\u03c4\u03ac \u03c4\u03b7 \u03b4\u03b9\u03ac\u03b3\u03bd\u03c9\u03c3\u03b7, \u03c5\u03c0\u03bf\u03b4\u03b7\u03bb\u03ce\u03bd\u03bf\u03bd\u03c4\u03b1\u03c2 \u03c4\u03b7\u03bd \u03c0\u03b1\u03c1\u03bf\u03c5\u03c3\u03af\u03b1 \u03bc\u03b9\u03b1\u03c2 \u03b5\u03bd\u03b5\u03c1\u03b3\u03bf\u03cd \u03b5\u03c0\u03af\u03bc\u03bf\u03bd\u03b7\u03c2 \u03b4\u03b5\u03be\u03b1\u03bc\u03b5\u03bd\u03ae\u03c2 \u03b9\u03bf\u03cd SARS-CoV-2. \u0395\u03c0\u03b9\u03c0\u03bb\u03ad\u03bf\u03bd, \u03c4\u03b1 \u03c7\u03c1\u03bf\u03bd\u03b9\u03ba\u03ac \u03c0\u03c1\u03bf\u03c6\u03af\u03bb \u03b1\u03bd\u03c4\u03b9\u03b3\u03cc\u03bd\u03bf\u03c5 \u03b3\u03b9\u03b1 \u03c0\u03bf\u03bb\u03bb\u03bf\u03cd\u03c2 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03b4\u03b5\u03af\u03c7\u03bd\u03bf\u03c5\u03bd \u03c4\u03b7\u03bd \u03c0\u03b1\u03c1\u03bf\u03c5\u03c3\u03af\u03b1 \u03b1\u03b9\u03c7\u03bc\u03ae\u03c2 \u03c3\u03b5 \u03c0\u03bf\u03bb\u03bb\u03b1\u03c0\u03bb\u03ac \u03c7\u03c1\u03bf\u03bd\u03b9\u03ba\u03ac \u03c3\u03b7\u03bc\u03b5\u03af\u03b1 \u03b3\u03b9\u03b1 \u03b1\u03c1\u03ba\u03b5\u03c4\u03bf\u03cd\u03c2 \u03bc\u03ae\u03bd\u03b5\u03c2, \u03c5\u03c0\u03bf\u03b3\u03c1\u03b1\u03bc\u03bc\u03af\u03b6\u03bf\u03bd\u03c4\u03b1\u03c2 \u03c4\u03b7\u03bd \u03c0\u03b9\u03b8\u03b1\u03bd\u03ae \u03c7\u03c1\u03b7\u03c3\u03b9\u03bc\u03cc\u03c4\u03b7\u03c4\u03b1 \u03c4\u03b7\u03c2 \u03c0\u03c1\u03c9\u03c4\u03b5\u0390\u03bd\u03b7\u03c2 \u03c0\u03bb\u03ae\u03c1\u03bf\u03c5\u03c2 \u03b1\u03ba\u03af\u03b4\u03b1\u03c2 SARS-CoV-2 \u03c9\u03c2 \u03b2\u03b9\u03bf\u03b4\u03b5\u03af\u03ba\u03c4\u03b7 \u03b3\u03b9\u03b1 \u03c4\u03bf PASC.<\/p>\n<\/div>\n<div id=\"sec-1\" class=\"section\">\n<h2 class=\"\">\u0395\u03b9\u03c3\u03b1\u03b3\u03c9\u03b3\u03ae<\/h2>\n<p id=\"p-15\">\u0395\u03bd\u03ce \u03c4\u03b1 \u03c3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03b1 \u03c0\u03bf\u03c5 \u03c0\u03c1\u03bf\u03ba\u03cd\u03c0\u03c4\u03bf\u03c5\u03bd \u03b1\u03c0\u03cc \u03bc\u03cc\u03bb\u03c5\u03bd\u03c3\u03b7 \u03bc\u03b5 \u03c3\u03bf\u03b2\u03b1\u03c1\u03cc \u03bf\u03be\u03cd \u03b1\u03bd\u03b1\u03c0\u03bd\u03b5\u03c5\u03c3\u03c4\u03b9\u03ba\u03cc \u03c3\u03cd\u03bd\u03b4\u03c1\u03bf\u03bc\u03bf \u03ba\u03bf\u03c1\u03bf\u03bd\u03b1\u03ca\u03cc\u03c2 2 (SARS-CoV-2) \u03c4\u03c5\u03c0\u03b9\u03ba\u03ac \u03c5\u03c0\u03bf\u03c7\u03c9\u03c1\u03bf\u03cd\u03bd \u03bc\u03ad\u03c3\u03b1 \u03c3\u03b5 \u03bb\u03af\u03b3\u03b5\u03c2 \u03b5\u03b2\u03b4\u03bf\u03bc\u03ac\u03b4\u03b5\u03c2, \u03bf\u03c1\u03b9\u03c3\u03bc\u03ad\u03bd\u03b1 \u03ac\u03c4\u03bf\u03bc\u03b1 \u03b5\u03bc\u03c6\u03b1\u03bd\u03af\u03b6\u03bf\u03c5\u03bd \u03b5\u03c0\u03af\u03bc\u03bf\u03bd\u03b1 \u03c3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03b1 \u03bc\u03b5\u03c4\u03ac \u03c4\u03b7\u03bd \u03bf\u03be\u03b5\u03af\u03b1 \u03c6\u03ac\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03bd\u03cc\u03c3\u03bf\u03c5 \u03c4\u03bf\u03c5 \u03ba\u03bf\u03c1\u03bf\u03bd\u03b1\u03ca\u03bf\u03cd (COVID-19). \u03a4\u03bf \u03c3\u03c7\u03b5\u03c4\u03b9\u03ba\u03cc \u03c3\u03cd\u03bd\u03b4\u03c1\u03bf\u03bc\u03bf, \u03c0\u03bf\u03c5 \u03bf\u03bd\u03bf\u03bc\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03bc\u03b5\u03c4\u03b1-\u03bf\u03be\u03b5\u03af\u03b1 \u03b5\u03c0\u03b1\u03ba\u03cc\u03bb\u03bf\u03c5\u03b8\u03b1 \u03c4\u03bf\u03c5 COVID-19 (PASC) \u03ae \u03bc\u03b1\u03ba\u03c1\u03ac COVID-19, \u03c0\u03b5\u03c1\u03b9\u03bb\u03b1\u03bc\u03b2\u03ac\u03bd\u03b5\u03b9 \u03bc\u03b9\u03b1 \u03c3\u03b5\u03b9\u03c1\u03ac \u03c3\u03c5\u03bc\u03c0\u03c4\u03c9\u03bc\u03ac\u03c4\u03c9\u03bd, \u03cc\u03c0\u03c9\u03c2, \u03b5\u03bd\u03b4\u03b5\u03b9\u03ba\u03c4\u03b9\u03ba\u03ac, <strong>\u03ba\u03cc\u03c0\u03c9\u03c3\u03b7, \u03b1\u03bd\u03bf\u03c3\u03bc\u03af\u03b1, \u03b1\u03c0\u03ce\u03bb\u03b5\u03b9\u03b1 \u03bc\u03bd\u03ae\u03bc\u03b7\u03c2, \u03b3\u03b1\u03c3\u03c4\u03c1\u03b5\u03bd\u03c4\u03b5\u03c1\u03b9\u03ba\u03ae \u03b4\u03c5\u03c3\u03c6\u03bf\u03c1\u03af\u03b1 \u03ba\u03b1\u03b9 \u03b4\u03cd\u03c3\u03c0\u03bd\u03bf\u03b9\u03b1. <\/strong><sup><a id=\"xref-ref-1-1\" class=\"xref-bibr article-ref-popup hasTooltip\" href=\"https:\/\/www.medrxiv.org\/content\/10.1101\/2022.06.14.22276401v1.full#ref-1\" data-hasqtip=\"5\">1 <\/a>\u2212 <a id=\"xref-ref-7-1\" class=\"xref-bibr article-ref-popup hasTooltip\" href=\"https:\/\/www.medrxiv.org\/content\/10.1101\/2022.06.14.22276401v1.full#ref-7\" data-hasqtip=\"4\" aria-describedby=\"qtip-4\">7 <\/a><\/sup>\u039f\u03b9 \u03b5\u03ba\u03c4\u03b9\u03bc\u03ae\u03c3\u03b5\u03b9\u03c2 \u03c0\u03bf\u03b9\u03ba\u03af\u03bb\u03bb\u03bf\u03c5\u03bd \u03c9\u03c2 \u03c0\u03c1\u03bf\u03c2 \u03c4\u03bf\u03bd \u03b5\u03c0\u03b9\u03c0\u03bf\u03bb\u03b1\u03c3\u03bc\u03cc \u03c4\u03bf\u03c5 PASC, <sup><a id=\"xref-ref-8-1\" class=\"xref-bibr article-ref-popup hasTooltip\" href=\"https:\/\/www.medrxiv.org\/content\/10.1101\/2022.06.14.22276401v1.full#ref-8\" data-hasqtip=\"6\" aria-describedby=\"qtip-6\">8 <\/a>\u2212 <a id=\"xref-ref-11-1\" class=\"xref-bibr\" href=\"https:\/\/www.medrxiv.org\/content\/10.1101\/2022.06.14.22276401v1.full#ref-11\">11 <\/a><\/sup>, \u03b1\u03bb\u03bb\u03ac \u03bf \u03a0\u03b1\u03b3\u03ba\u03cc\u03c3\u03bc\u03b9\u03bf\u03c2 \u039f\u03c1\u03b3\u03b1\u03bd\u03b9\u03c3\u03bc\u03cc\u03c2 \u03a5\u03b3\u03b5\u03af\u03b1\u03c2 (\u03a0\u039f\u03a5) \u03b1\u03bd\u03b1\u03c6\u03ad\u03c1\u03b5\u03b9 \u03cc\u03c4\u03b9 \u03c0\u03b5\u03c1\u03af\u03c0\u03bf\u03c5 \u03c4\u03bf \u03ad\u03bd\u03b1 \u03c4\u03ad\u03c4\u03b1\u03c1\u03c4\u03bf \u03c4\u03c9\u03bd \u03b1\u03c4\u03cc\u03bc\u03c9\u03bd \u03bc\u03b5 COVID-19 \u03c3\u03c5\u03bd\u03b5\u03c7\u03af\u03b6\u03bf\u03c5\u03bd \u03bd\u03b1 \u03b5\u03bc\u03c6\u03b1\u03bd\u03af\u03b6\u03bf\u03c5\u03bd \u03c3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03b1 4-5 \u03b5\u03b2\u03b4\u03bf\u03bc\u03ac\u03b4\u03b5\u03c2 \u03bc\u03b5\u03c4\u03ac \u03b1\u03c0\u03cc \u03ad\u03bd\u03b1 \u03b8\u03b5\u03c4\u03b9\u03ba\u03cc \u03c4\u03b5\u03c3\u03c4 \u03ba\u03b1\u03b9 \u03c0\u03b5\u03c1\u03af\u03c0\u03bf\u03c5 \u03ad\u03bd\u03b1\u03c2 \u03c3\u03c4\u03bf\u03c5\u03c2 10 \u03ad\u03c7\u03bf\u03c5\u03bd \u03c3\u03c5\u03bd\u03b5\u03c7\u03ae \u03c3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03b1 \u03bc\u03b5\u03c4\u03ac \u03b1\u03c0\u03cc 12 \u03b5\u03b2\u03b4\u03bf\u03bc\u03ac\u03b4\u03b5\u03c2. <sup><a id=\"xref-ref-12-1\" class=\"xref-bibr\" href=\"https:\/\/www.medrxiv.org\/content\/10.1101\/2022.06.14.22276401v1.full#ref-12\">12 <\/a><\/sup><\/p>\n<p id=\"p-16\">\u0391\u03bd \u03ba\u03b1\u03b9 \u03c0\u03c1\u03cc\u03c3\u03c6\u03b1\u03c4\u03b5\u03c2 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b5\u03c2 \u03c0\u03b1\u03c1\u03ad\u03c7\u03bf\u03c5\u03bd \u03ba\u03ac\u03c0\u03bf\u03b9\u03b5\u03c2 \u03b5\u03bd\u03b4\u03b5\u03af\u03be\u03b5\u03b9\u03c2, \u03b7 \u03c5\u03c0\u03bf\u03ba\u03b5\u03af\u03bc\u03b5\u03bd\u03b7 \u03b1\u03b9\u03c4\u03b9\u03bf\u03bb\u03bf\u03b3\u03af\u03b1 \u03c4\u03bf\u03c5 PASC \u03c0\u03b1\u03c1\u03b1\u03bc\u03ad\u03bd\u03b5\u03b9\u00a0 \u03c3\u03c4\u03b9\u03c2 \u03c5\u03c0\u03bf\u03b8\u03ad\u03c3\u03b5\u03b9\u03c2. <sup><a id=\"xref-ref-13-1\" class=\"xref-bibr\" href=\"https:\/\/www.medrxiv.org\/content\/10.1101\/2022.06.14.22276401v1.full#ref-13\">13 <\/a><\/sup>\u0391\u03c5\u03c4\u03ae \u03b7 \u03ad\u03bb\u03bb\u03b5\u03b9\u03c8\u03b7 \u03bc\u03b7\u03c7\u03b1\u03bd\u03b9\u03c3\u03c4\u03b9\u03ba\u03ae\u03c2 \u03c3\u03b1\u03c6\u03ae\u03bd\u03b5\u03b9\u03b1\u03c2 \u03bf\u03c6\u03b5\u03af\u03bb\u03b5\u03c4\u03b1\u03b9 \u03b5\u03bd \u03bc\u03ad\u03c1\u03b5\u03b9 \u03c3\u03c4\u03b7\u03bd \u03b5\u03c4\u03b5\u03c1\u03bf\u03b3\u03ad\u03bd\u03b5\u03b9\u03b1 \u03c4\u03b7\u03c2 \u03c0\u03c1\u03cc\u03c3\u03bb\u03b7\u03c8\u03b7\u03c2 \u03b1\u03c3\u03b8\u03b5\u03bd\u03ce\u03bd \u03ba\u03b1\u03b9 \u03c3\u03c4\u03b9\u03c2 \u03b1\u03c3\u03c5\u03bd\u03ad\u03c0\u03b5\u03b9\u03b5\u03c2 \u03c3\u03c4\u03bf\u03bd \u03bf\u03c1\u03b9\u03c3\u03bc\u03cc \u03c4\u03c9\u03bd \u03b1\u03c3\u03b8\u03b5\u03bd\u03ce\u03bd \u03bc\u03b5 PASC, \u03b3\u03b5\u03b3\u03bf\u03bd\u03cc\u03c2 \u03c0\u03bf\u03c5 \u03ba\u03b1\u03b8\u03b9\u03c3\u03c4\u03ac \u03b4\u03cd\u03c3\u03ba\u03bf\u03bb\u03b7 \u03c4\u03b7\u03bd \u03b5\u03bd\u03c3\u03c9\u03bc\u03ac\u03c4\u03c9\u03c3\u03b7 \u03c4\u03c9\u03bd \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03b5\u03c3\u03bc\u03ac\u03c4\u03c9\u03bd \u03c3\u03c4\u03b9\u03c2 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b5\u03c2. \u0397 \u03b1\u03c0\u03bf\u03c3\u03cd\u03bd\u03b4\u03b5\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03c0\u03bf\u03bb\u03cd\u03c0\u03bb\u03bf\u03ba\u03b7\u03c2 \u03b2\u03b9\u03bf\u03bb\u03bf\u03b3\u03af\u03b1\u03c2 \u03c4\u03bf\u03c5 PASC \u03b8\u03b1 \u03b2\u03b1\u03c3\u03af\u03b6\u03b5\u03c4\u03b1\u03b9 \u03c3\u03c4\u03b7\u03bd \u03b1\u03bd\u03b1\u03b3\u03bd\u03ce\u03c1\u03b9\u03c3\u03b7 \u03b2\u03b9\u03bf\u03b4\u03b5\u03b9\u03ba\u03c4\u03ce\u03bd \u03c0\u03bf\u03c5 \u03b5\u03c0\u03b9\u03c4\u03c1\u03ad\u03c0\u03bf\u03c5\u03bd \u03c4\u03b7\u03bd \u03c4\u03b1\u03be\u03b9\u03bd\u03cc\u03bc\u03b7\u03c3\u03b7 \u03c4\u03c9\u03bd \u03c6\u03b1\u03b9\u03bd\u03bf\u03c4\u03cd\u03c0\u03c9\u03bd \u03c4\u03c9\u03bd \u03b1\u03c3\u03b8\u03b5\u03bd\u03ce\u03bd. \u0395\u03b4\u03ce, \u03b1\u03bd\u03b1\u03bb\u03cd\u03bf\u03c5\u03bc\u03b5 \u03b4\u03b5\u03af\u03b3\u03bc\u03b1\u03c4\u03b1 \u03c0\u03bb\u03ac\u03c3\u03bc\u03b1\u03c4\u03bf\u03c2 \u03c0\u03bf\u03c5 \u03c3\u03c5\u03bb\u03bb\u03ad\u03c7\u03b8\u03b7\u03ba\u03b1\u03bd \u03b1\u03c0\u03cc \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 PASC \u03ba\u03b1\u03b9 COVID-19 \u03b3\u03b9\u03b1 \u03bd\u03b1 \u03c0\u03c1\u03bf\u03c3\u03b4\u03b9\u03bf\u03c1\u03af\u03c3\u03bf\u03c5\u03bc\u03b5 \u03c4\u03b1 \u03b5\u03c0\u03af\u03c0\u03b5\u03b4\u03b1 \u03c4\u03c9\u03bd \u03b1\u03bd\u03c4\u03b9\u03b3\u03cc\u03bd\u03c9\u03bd \u03ba\u03b1\u03b9 \u03c4\u03c9\u03bd \u03ba\u03c5\u03c4\u03bf\u03ba\u03b9\u03bd\u03ce\u03bd SARS-CoV-2 \u03ba\u03b1\u03b9 \u03bd\u03b1 \u03b5\u03bd\u03c4\u03bf\u03c0\u03af\u03c3\u03bf\u03c5\u03bc\u03b5 \u03ad\u03bd\u03b1\u03bd \u03b2\u03b9\u03bf\u03b4\u03b5\u03af\u03ba\u03c4\u03b7 \u03b1\u03af\u03bc\u03b1\u03c4\u03bf\u03c2 \u03c0\u03bf\u03c5 \u03b5\u03bc\u03c6\u03b1\u03bd\u03af\u03b6\u03b5\u03c4\u03b1\u03b9 \u03c3\u03c4\u03b7\u03bd \u03c0\u03bb\u03b5\u03b9\u03bf\u03bd\u03cc\u03c4\u03b7\u03c4\u03b1 \u03c4\u03c9\u03bd \u03b1\u03c3\u03b8\u03b5\u03bd\u03ce\u03bd \u03bc\u03b5 PASC.<\/p>\n<\/div>\n<div id=\"sec-2\" class=\"section\">\n<h2 class=\"\">\u0391\u03c0\u03bf\u03c4\u03b5\u03bb\u03ad\u03c3\u03bc\u03b1\u03c4\u03b1<\/h2>\n<p id=\"p-17\">\u0391\u03bd\u03b1\u03bb\u03cd\u03c3\u03b1\u03bc\u03b5 \u03b4\u03b5\u03af\u03b3\u03bc\u03b1\u03c4\u03b1 \u03c0\u03bb\u03ac\u03c3\u03bc\u03b1\u03c4\u03bf\u03c2 \u03b1\u03c0\u03cc \u03bc\u03b9\u03b1 \u03bf\u03bc\u03ac\u03b4\u03b1 63 \u03b1\u03c4\u03cc\u03bc\u03c9\u03bd \u03c0\u03bf\u03c5 \u03b5\u03af\u03c7\u03b1\u03bd \u03bc\u03bf\u03bb\u03c5\u03bd\u03b8\u03b5\u03af \u03c0\u03c1\u03bf\u03b7\u03b3\u03bf\u03c5\u03bc\u03ad\u03bd\u03c9\u03c2 \u03bc\u03b5 SARS-CoV-2, 37 \u03b1\u03c0\u03cc \u03c4\u03b1 \u03bf\u03c0\u03bf\u03af\u03b1 \u03b5\u03af\u03c7\u03b1\u03bd \u03b4\u03b9\u03b1\u03b3\u03bd\u03c9\u03c3\u03c4\u03b5\u03af \u03bc\u03b5 PASC. \u0393\u03b9\u03b1 \u03c4\u03bf\u03c5\u03c2 \u03c0\u03b5\u03c1\u03b9\u03c3\u03c3\u03cc\u03c4\u03b5\u03c1\u03bf\u03c5\u03c2 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 PASC (n= 31), \u03b4\u03b5\u03af\u03b3\u03bc\u03b1\u03c4\u03b1 \u03b1\u03af\u03bc\u03b1\u03c4\u03bf\u03c2 \u03c3\u03c5\u03bb\u03bb\u03ad\u03c7\u03b8\u03b7\u03ba\u03b1\u03bd \u03b4\u03cd\u03bf \u03ae \u03c0\u03b5\u03c1\u03b9\u03c3\u03c3\u03cc\u03c4\u03b5\u03c1\u03b5\u03c2 \u03c6\u03bf\u03c1\u03ad\u03c2 \u03ad\u03c9\u03c2 \u03ba\u03b1\u03b9 12 \u03bc\u03ae\u03bd\u03b5\u03c2 \u03bc\u03b5\u03c4\u03ac \u03c4\u03bf \u03c0\u03c1\u03ce\u03c4\u03bf \u03c4\u03bf\u03c5\u03c2 \u03b8\u03b5\u03c4\u03b9\u03ba\u03cc \u03b1\u03c0\u03bf\u03c4\u03ad\u03bb\u03b5\u03c3\u03bc\u03b1 \u03b5\u03af\u03c4\u03b5 \u03bc\u03b5 \u03c4\u03b5\u03c3\u03c4 RT-PCR \u03bc\u03b5 \u03c1\u03b9\u03bd\u03bf\u03c6\u03b1\u03c1\u03c5\u03b3\u03b3\u03b9\u03ba\u03cc \u03c3\u03c4\u03c5\u03bb\u03b5\u03cc \u03b5\u03af\u03c4\u03b5 \u03bc\u03b5 \u03c4\u03b5\u03c3\u03c4 \u03b1\u03bd\u03c4\u03b9\u03c3\u03c9\u03bc\u03ac\u03c4\u03c9\u03bd \u03ba\u03b1\u03c4\u03ac \u03c4\u03bf\u03c5 SARS-CoV-2. \u03a3\u03c5\u03bb\u03bb\u03ad\u03c7\u03c4\u03b7\u03ba\u03b5 \u03b5\u03c0\u03af\u03c3\u03b7\u03c2 \u03b1\u03af\u03bc\u03b1 \u03b1\u03c0\u03cc \u03ac\u03c4\u03bf\u03bc\u03b1 \u03c0\u03bf\u03c5 \u03ad\u03c0\u03b1\u03c3\u03c7\u03b1\u03bd \u03b1\u03c0\u03cc COVID-19, \u03b1\u03bb\u03bb\u03ac \u03b4\u03b5\u03bd \u03b5\u03af\u03c7\u03b1\u03bd \u03b4\u03b9\u03b1\u03b3\u03bd\u03c9\u03c3\u03c4\u03b5\u03af \u03bc\u03b5 PASC, \u03ad\u03c9\u03c2 \u03ba\u03b1\u03b9 \u03c0\u03ad\u03bd\u03c4\u03b5 \u03bc\u03ae\u03bd\u03b5\u03c2 \u03bc\u03b5\u03c4\u03ac \u03c4\u03b7 \u03b4\u03b9\u03ac\u03b3\u03bd\u03c9\u03c3\u03b7. \u0397 \u03c0\u03bb\u03b5\u03b9\u03bf\u03bd\u03cc\u03c4\u03b7\u03c4\u03b1 \u03c4\u03c9\u03bd \u03b1\u03c3\u03b8\u03b5\u03bd\u03ce\u03bd \u03bc\u03b5 PASC \u03ae\u03c4\u03b1\u03bd \u03b3\u03c5\u03bd\u03b1\u03af\u03ba\u03b5\u03c2 (n = 30), \u03c3\u03cd\u03bc\u03c6\u03c9\u03bd\u03b1 \u03bc\u03b5 \u03ac\u03bb\u03bb\u03b5\u03c2 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b5\u03c2 \u03c0\u03bf\u03c5 \u03b4\u03b9\u03b1\u03c0\u03af\u03c3\u03c4\u03c9\u03c3\u03b1\u03bd \u03cc\u03c4\u03b9 \u03bf\u03b9 \u03b3\u03c5\u03bd\u03b1\u03af\u03ba\u03b5\u03c2 \u03b5\u03c0\u03b7\u03c1\u03b5\u03ac\u03b6\u03bf\u03bd\u03c4\u03b1\u03b9 \u03ba\u03c5\u03c1\u03af\u03c9\u03c2 \u03b1\u03c0\u03cc \u03b5\u03c0\u03af\u03bc\u03bf\u03bd\u03b1 \u03c3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03b1 \u03bc\u03b5\u03c4\u03ac \u03c4\u03b7 \u03bc\u03cc\u03bb\u03c5\u03bd\u03c3\u03b7 \u03b1\u03c0\u03cc SARS-CoV-2. <sup><a id=\"xref-ref-11-2\" class=\"xref-bibr\" href=\"https:\/\/www.medrxiv.org\/content\/10.1101\/2022.06.14.22276401v1.full#ref-11\">11 <\/a>, <a id=\"xref-ref-14-1\" class=\"xref-bibr\" href=\"https:\/\/www.medrxiv.org\/content\/10.1101\/2022.06.14.22276401v1.full#ref-14\">14 <\/a>\u2212 <a id=\"xref-ref-16-1\" class=\"xref-bibr\" href=\"https:\/\/www.medrxiv.org\/content\/10.1101\/2022.06.14.22276401v1.full#ref-16\">16 <\/a><\/sup>\u0391\u03c0\u03cc \u03c4\u03b1 \u03ac\u03c4\u03bf\u03bc\u03b1 \u03c0\u03bf\u03c5 \u03b4\u03b5\u03bd \u03b4\u03b9\u03b1\u03b3\u03bd\u03ce\u03c3\u03c4\u03b7\u03ba\u03b1\u03bd \u03bc\u03b5 PASC (n = 26), \u03b4\u03ad\u03ba\u03b1 \u03b5\u03b9\u03c3\u03ae\u03c7\u03b8\u03b7\u03c3\u03b1\u03bd \u03c3\u03c4\u03b7 \u03bc\u03bf\u03bd\u03ac\u03b4\u03b1 \u03b5\u03bd\u03c4\u03b1\u03c4\u03b9\u03ba\u03ae\u03c2 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1\u03c2 (\u039c\u0395\u0398) \u03ba\u03b1\u03b9 \u03b5\u03c0\u03c4\u03ac \u03b4\u03b9\u03b1\u03c3\u03c9\u03bb\u03b7\u03bd\u03ce\u03b8\u03b7\u03ba\u03b1\u03bd. \u039c\u03b9\u03b1 \u03c0\u03bb\u03ae\u03c1\u03b7\u03c2 \u03b5\u03c0\u03b9\u03c3\u03ba\u03cc\u03c0\u03b7\u03c3\u03b7 \u03c4\u03c9\u03bd \u03c7\u03b1\u03c1\u03b1\u03ba\u03c4\u03b7\u03c1\u03b9\u03c3\u03c4\u03b9\u03ba\u03ce\u03bd \u03c4\u03bf\u03c5 \u03b1\u03c3\u03b8\u03b5\u03bd\u03bf\u03cd\u03c2 \u03c0\u03b1\u03c1\u03ad\u03c7\u03b5\u03c4\u03b1\u03b9 \u03c3\u03c4\u03bf\u03bd <a id=\"xref-table-wrap-1-1\" class=\"xref-table\" href=\"https:\/\/www.medrxiv.org\/content\/10.1101\/2022.06.14.22276401v1.full#T1\">\u03a3\u03c5\u03bc\u03c0\u03bb\u03b7\u03c1\u03c9\u03bc\u03b1\u03c4\u03b9\u03ba\u03cc \u03a0\u03af\u03bd\u03b1\u03ba\u03b1 1 <\/a>.<\/p>\n<div id=\"T1\" class=\"table pos-float\">\n<div class=\"table-inline table-callout-links\">\n<div class=\"callout\">\n<ul class=\"callout-links\">\n<li class=\"view-inline first\"><a class=\"table-expand-inline highwireTablesMarkupProcessor-processed\" href=\"https:\/\/www.medrxiv.org\/content\/10.1101\/2022.06.14.22276401v1.full##\" data-table-url=\"\/highwire\/markup\/528448\/expansion?postprocessors=highwire_tables%2Chighwire_reclass%2Chighwire_figures%2Chighwire_math%2Chighwire_inline_linked_media%2Chighwire_embed&amp;table-expand-inline=1\" data-icon-position=\"\" data-hide-link-title=\"0\">\u03a0\u03c1\u03bf\u03b2\u03bf\u03bb\u03ae \u03b5\u03bd\u03c3\u03c9\u03bc\u03b1\u03c4\u03c9\u03bc\u03ad\u03bd\u03b7 <\/a><\/li>\n<li class=\"view-popup\"><a class=\"colorbox colorbox-load table-expand-popup init-colorbox-processed cboxElement\" href=\"https:\/\/www.medrxiv.org\/highwire\/markup\/528448\/expansion?width=1000&amp;height=500&amp;iframe=true&amp;postprocessors=highwire_tables%2Chighwire_reclass%2Chighwire_figures%2Chighwire_math%2Chighwire_inline_linked_media%2Chighwire_embed\" rel=\"gallery-fragment-tables\" data-icon-position=\"\" data-hide-link-title=\"0\">\u03a0\u03c1\u03bf\u03b2\u03bf\u03bb\u03ae \u03b1\u03bd\u03b1\u03b4\u03c5\u03cc\u03bc\u03b5\u03bd\u03bf\u03c5 \u03c0\u03b1\u03c1\u03b1\u03b8\u03cd\u03c1\u03bf\u03c5 <\/a><\/li>\n<\/ul>\n<\/div>\n<\/div>\n<div class=\"table-caption\">\n<p><span class=\"table-label\">\u03a3\u03c5\u03bc\u03c0\u03bb\u03b7\u03c1\u03c9\u03bc\u03b1\u03c4\u03b9\u03ba\u03cc\u03c2 \u03a0\u03af\u03bd\u03b1\u03ba\u03b1\u03c2 1. <\/span><\/p>\n<p id=\"p-34\" class=\"first-child\">\u03a7\u03b1\u03c1\u03b1\u03ba\u03c4\u03b7\u03c1\u03b9\u03c3\u03c4\u03b9\u03ba\u03ac \u03b1\u03c3\u03b8\u03b5\u03bd\u03ce\u03bd \u03b3\u03b9\u03b1 \u03c4\u03b9\u03c2 \u03ba\u03bf\u03cc\u03c1\u03c4\u03b5\u03c2 PASC \u03ba\u03b1\u03b9 COVID-19.<\/p>\n<div class=\"sb-div caption-clear\"><\/div>\n<\/div>\n<\/div>\n<p id=\"p-18\">\u03a7\u03c1\u03b7\u03c3\u03b9\u03bc\u03bf\u03c0\u03bf\u03b9\u03ce\u03bd\u03c4\u03b1\u03c2 \u03c0\u03c1\u03bf\u03b7\u03b3\u03bf\u03c5\u03bc\u03ad\u03bd\u03c9\u03c2 \u03b1\u03bd\u03b1\u03c0\u03c4\u03c5\u03b3\u03bc\u03ad\u03bd\u03b5\u03c2 \u03ba\u03b1\u03b9 \u03b2\u03b5\u03bb\u03c4\u03b9\u03c3\u03c4\u03bf\u03c0\u03bf\u03b9\u03b7\u03bc\u03ad\u03bd\u03b5\u03c2 \u03b4\u03bf\u03ba\u03b9\u03bc\u03ad\u03c2 \u03c5\u03c0\u03b5\u03c1\u03b5\u03c5\u03b1\u03af\u03c3\u03b8\u03b7\u03c4\u03b7\u03c2 \u03c3\u03c5\u03c3\u03c4\u03bf\u03b9\u03c7\u03af\u03b1\u03c2 \u03bc\u03bf\u03c1\u03af\u03c9\u03bd (Simoa), \u03bc\u03b5\u03c4\u03c1\u03ae\u03c3\u03b1\u03bc\u03b5 \u03c4\u03b7 \u03c3\u03c5\u03b3\u03ba\u03ad\u03bd\u03c4\u03c1\u03c9\u03c3\u03b7 \u03c4\u03c9\u03bd \u03b1\u03bd\u03c4\u03b9\u03b3\u03cc\u03bd\u03c9\u03bd SARS-CoV-2, \u03c3\u03c5\u03bc\u03c0\u03b5\u03c1\u03b9\u03bb\u03b1\u03bc\u03b2\u03b1\u03bd\u03bf\u03bc\u03ad\u03bd\u03b7\u03c2 \u03c4\u03b7\u03c2 \u03c5\u03c0\u03bf\u03bc\u03bf\u03bd\u03ac\u03b4\u03b1\u03c2 S1 \u03c4\u03b7\u03c2 \u03b1\u03ba\u03af\u03b4\u03b1\u03c2, \u03c4\u03b7\u03c2 \u03b1\u03ba\u03af\u03b4\u03b1\u03c2 \u03c0\u03bb\u03ae\u03c1\u03bf\u03c5\u03c2 \u03bc\u03ae\u03ba\u03bf\u03c5\u03c2 \u03ba\u03b1\u03b9 \u03c4\u03bf\u03c5 \u03bd\u03bf\u03c5\u03ba\u03bb\u03b5\u03bf\u03ba\u03b1\u03c8\u03b9\u03b4\u03af\u03bf\u03c5 (\u039d), \u03c3\u03c4\u03b1 \u03c3\u03c5\u03bb\u03bb\u03b5\u03c7\u03b8\u03ad\u03bd\u03c4\u03b1 \u03b4\u03b5\u03af\u03b3\u03bc\u03b1\u03c4\u03b1 \u03c0\u03bb\u03ac\u03c3\u03bc\u03b1\u03c4\u03bf\u03c2 ( <a id=\"xref-fig-1-1\" class=\"xref-fig\" href=\"https:\/\/www.medrxiv.org\/content\/10.1101\/2022.06.14.22276401v1.full#F1\">\u0395\u03b9\u03ba\u03cc\u03bd\u03b1 1 <\/a>). <sup><a id=\"xref-ref-17-1\" class=\"xref-bibr\" href=\"https:\/\/www.medrxiv.org\/content\/10.1101\/2022.06.14.22276401v1.full#ref-17\">17 <\/a>\u2212 <a id=\"xref-ref-19-1\" class=\"xref-bibr\" href=\"https:\/\/www.medrxiv.org\/content\/10.1101\/2022.06.14.22276401v1.full#ref-19\">19 <\/a><\/sup>\u039c\u03c0\u03bf\u03c1\u03ad\u03c3\u03b1\u03bc\u03b5 \u03bd\u03b1 \u03b1\u03bd\u03b9\u03c7\u03bd\u03b5\u03cd\u03c3\u03bf\u03c5\u03bc\u03b5 \u03b5\u03af\u03c4\u03b5 S1, \u03b1\u03ba\u03af\u03b4\u03b1 \u03ae \u039d \u03c3\u03b5 \u03c0\u03b5\u03c1\u03af\u03c0\u03bf\u03c5 65% \u03c4\u03c9\u03bd \u03b1\u03c3\u03b8\u03b5\u03bd\u03ce\u03bd \u03c0\u03bf\u03c5 \u03b4\u03b9\u03b1\u03b3\u03bd\u03ce\u03c3\u03c4\u03b7\u03ba\u03b1\u03bd \u03bc\u03b5 PASC \u03c3\u03b5 \u03bf\u03c0\u03bf\u03b9\u03b1\u03b4\u03ae\u03c0\u03bf\u03c4\u03b5 \u03b4\u03b5\u03b4\u03bf\u03bc\u03ad\u03bd\u03b7 \u03c7\u03c1\u03bf\u03bd\u03b9\u03ba\u03ae \u03c3\u03c4\u03b9\u03b3\u03bc\u03ae, \u03b1\u03c1\u03ba\u03b5\u03c4\u03bf\u03cd\u03c2 \u03bc\u03ae\u03bd\u03b5\u03c2 \u03bc\u03b5\u03c4\u03ac \u03c4\u03b7 \u03bc\u03cc\u03bb\u03c5\u03bd\u03c3\u03b7 \u03b1\u03c0\u03cc SARS-CoV-2. \u039a\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03b1 \u03c4\u03c1\u03af\u03b1 \u03b1\u03bd\u03c4\u03b9\u03b3\u03cc\u03bd\u03b1 \u03c0\u03bf\u03c5 \u03bc\u03b5\u03c4\u03c1\u03ae\u03b8\u03b7\u03ba\u03b1\u03bd, <strong>\u03b5\u03bd\u03c4\u03bf\u03c0\u03af\u03c3\u03b1\u03bc\u03b5 \u03b1\u03ba\u03af\u03b4\u03b1 \u03c3\u03c5\u03c7\u03bd\u03cc\u03c4\u03b5\u03c1\u03b1 \u03c3\u03c4\u03bf 60% \u03c4\u03c9\u03bd \u03b1\u03c3\u03b8\u03b5\u03bd\u03ce\u03bd \u03bc\u03b5 PASC, \u03b5\u03bd\u03ce \u03b4\u03b5\u03bd \u03b5\u03bd\u03c4\u03bf\u03c0\u03af\u03c3\u03b1\u03bc\u03b5 \u03ba\u03b1\u03b8\u03cc\u03bb\u03bf\u03c5 \u03b1\u03ba\u03af\u03b4\u03b1 \u03c3\u03c4\u03bf\u03c5\u03c2 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 COVID-19.<\/strong> \u03a4\u03bf S1 \u03b1\u03bd\u03b9\u03c7\u03bd\u03b5\u03cd\u03b8\u03b7\u03ba\u03b5 \u03c3\u03b5 \u03bc\u03b9\u03ba\u03c1\u03cc\u03c4\u03b5\u03c1\u03bf \u03b2\u03b1\u03b8\u03bc\u03cc \u03c3\u03c4\u03bf \u03ad\u03bd\u03b1 \u03c0\u03ad\u03bc\u03c0\u03c4\u03bf \u03c0\u03b5\u03c1\u03af\u03c0\u03bf\u03c5 \u03c4\u03c9\u03bd \u03b1\u03c3\u03b8\u03b5\u03bd\u03ce\u03bd \u03bc\u03b5 PASC \u03ba\u03b1\u03b9 \u03c4\u03bf \u039d \u03b1\u03bd\u03b9\u03c7\u03bd\u03b5\u03cd\u03b8\u03b7\u03ba\u03b5 \u03c3\u03b5 \u03ad\u03bd\u03b1\u03bd \u03bc\u03cc\u03bd\u03bf \u03b1\u03c3\u03b8\u03b5\u03bd\u03ae \u03c3\u03b5 \u03c0\u03bf\u03bb\u03bb\u03b1\u03c0\u03bb\u03ac \u03c7\u03c1\u03bf\u03bd\u03b9\u03ba\u03ac \u03c3\u03b7\u03bc\u03b5\u03af\u03b1. \u03a3\u03cd\u03bc\u03c6\u03c9\u03bd\u03b1 \u03bc\u03b5 \u03c4\u03b7\u03bd \u03c0\u03c1\u03bf\u03b7\u03b3\u03bf\u03cd\u03bc\u03b5\u03bd\u03b7 \u03b5\u03c1\u03b3\u03b1\u03c3\u03af\u03b1 \u03bc\u03b1\u03c2, <sup><a id=\"xref-ref-18-1\" class=\"xref-bibr\" href=\"https:\/\/www.medrxiv.org\/content\/10.1101\/2022.06.14.22276401v1.full#ref-18\">18 <\/a><\/sup>\u03b5\u03bd\u03c4\u03bf\u03c0\u03af\u03c3\u03b1\u03bc\u03b5 S1 \u03ba\u03b1\u03b9 N \u03c3\u03b5 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 COVID-19, \u03c3\u03c5\u03c7\u03bd\u03ac \u03c3\u03b5 \u03b1\u03c5\u03c4\u03bf\u03cd\u03c2 \u03c0\u03bf\u03c5 \u03bd\u03bf\u03c3\u03b7\u03bb\u03b5\u03cd\u03bf\u03bd\u03c4\u03b1\u03b9 \u03bc\u03b5 \u03c3\u03bf\u03b2\u03b1\u03c1\u03ae \u03bd\u03cc\u03c3\u03bf \u03ba\u03b1\u03b9 \u03b5\u03bd\u03c4\u03cc\u03c2 \u03c4\u03b7\u03c2 \u03c0\u03c1\u03ce\u03c4\u03b7\u03c2 \u03b5\u03b2\u03b4\u03bf\u03bc\u03ac\u03b4\u03b1\u03c2 \u03bc\u03b5\u03c4\u03ac \u03c4\u03b7 \u03b4\u03b9\u03ac\u03b3\u03bd\u03c9\u03c3\u03b7, \u03b1\u03bb\u03bb\u03ac \u03b4\u03b5\u03bd \u03b5\u03bd\u03c4\u03bf\u03c0\u03af\u03c3\u03b1\u03bc\u03b5 \u03c4\u03b7\u03bd \u03c0\u03bb\u03ae\u03c1\u03b7 \u03c0\u03c1\u03c9\u03c4\u03b5\u0390\u03bd\u03b7 \u03b1\u03ba\u03af\u03b4\u03b1\u03c2 \u03c3\u03b5 \u03ba\u03b1\u03bd\u03ad\u03bd\u03b1\u03bd \u03b1\u03c0\u03cc \u03b1\u03c5\u03c4\u03bf\u03cd\u03c2 \u03c4\u03bf\u03c5\u03c2 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2.<\/p>\n<div id=\"F1\" class=\"fig pos-float type-figure odd\">\n<div class=\"highwire-figure\">\n<div class=\"fig-inline-img-wrapper\">\n<div class=\"fig-inline-img\"><a class=\"highwire-fragment fragment-images colorbox-load highwireFiguresMarkupProcessor-processed cboxElement\" title=\"\u0395\u03c0\u03af\u03c0\u03b5\u03b4\u03b1 \u03b1\u03bd\u03c4\u03b9\u03b3\u03cc\u03bd\u03bf\u03c5 SARS-CoV-2 \u03c3\u03b5 \u03c3\u03c7\u03ad\u03c3\u03b7 \u03bc\u03b5 \u03c4\u03bf \u03c7\u03c1\u03cc\u03bd\u03bf. \u0397 \u03c3\u03c5\u03b3\u03ba\u03ad\u03bd\u03c4\u03c1\u03c9\u03c3\u03b7 \u03c4\u03bf\u03c5 S1 (A), \u03c4\u03b7\u03c2 \u03b1\u03ba\u03af\u03b4\u03b1\u03c2 (B) \u03ba\u03b1\u03b9 \u03c4\u03bf\u03c5 N (C) \u03bc\u03b5\u03c4\u03c1\u03ae\u03b8\u03b7\u03ba\u03b5 \u03c3\u03c4\u03bf \u03c0\u03bb\u03ac\u03c3\u03bc\u03b1 \u03c4\u03c9\u03bd \u03b1\u03c4\u03cc\u03bc\u03c9\u03bd \u03bc\u03b5 \u03c4\u03b7\u03bd \u03c0\u03ac\u03c1\u03bf\u03b4\u03bf \u03c4\u03bf\u03c5 \u03c7\u03c1\u03cc\u03bd\u03bf\u03c5 \u03bc\u03b5\u03c4\u03ac \u03c4\u03b7 \u03b4\u03b9\u03ac\u03b3\u03bd\u03c9\u03c3\u03b7 \u03bc\u03b5 PASC \u03ae COVID-19 \u03bc\u03b5\u03c4\u03ac \u03b1\u03c0\u03cc \u03bc\u03cc\u03bb\u03c5\u03bd\u03c3\u03b7 \u03b1\u03c0\u03cc SARS-CoV-2. \u03a0\u03bf\u03bb\u03bb\u03ac \u03c3\u03b7\u03bc\u03b5\u03af\u03b1 \u03b4\u03b5\u03b4\u03bf\u03bc\u03ad\u03bd\u03c9\u03bd \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b1\u03bd\u03c4\u03b9\u03c3\u03c4\u03bf\u03b9\u03c7\u03bf\u03cd\u03bd \u03c3\u03c4\u03bf \u03af\u03b4\u03b9\u03bf \u03ac\u03c4\u03bf\u03bc\u03bf, \u03cc\u03c0\u03bf\u03c5 \u03ae\u03c4\u03b1\u03bd \u03b4\u03b9\u03b1\u03b8\u03ad\u03c3\u03b9\u03bc\u03b7 \u03b7 \u03b5\u03c0\u03b1\u03bd\u03b1\u03bb\u03b7\u03c0\u03c4\u03b9\u03ba\u03ae \u03b4\u03b5\u03b9\u03b3\u03bc\u03b1\u03c4\u03bf\u03bb\u03b7\u03c8\u03af\u03b1. \u03a4\u03b1 \u03c3\u03b7\u03bc\u03b5\u03af\u03b1 \u03b4\u03b5\u03b4\u03bf\u03bc\u03ad\u03bd\u03c9\u03bd \u03b1\u03bd\u03c4\u03b9\u03c0\u03c1\u03bf\u03c3\u03c9\u03c0\u03b5\u03cd\u03bf\u03c5\u03bd \u03bc\u03ad\u03c3\u03b5\u03c2 \u03c4\u03b9\u03bc\u03ad\u03c2 \u00b1 SD (n = 2). \u039f\u03b9 \u03b4\u03b9\u03b1\u03ba\u03b5\u03ba\u03bf\u03bc\u03bc\u03ad\u03bd\u03b5\u03c2 \u03b3\u03c1\u03b1\u03bc\u03bc\u03ad\u03c2 \u03c5\u03c0\u03bf\u03b4\u03b5\u03b9\u03ba\u03bd\u03cd\u03bf\u03c5\u03bd \u03c4\u03bf LOD \u03b3\u03b9\u03b1 \u03ba\u03ac\u03b8\u03b5 \u03c0\u03c1\u03bf\u03c3\u03b4\u03b9\u03bf\u03c1\u03b9\u03c3\u03bc\u03cc.\" href=\"https:\/\/www.medrxiv.org\/content\/medrxiv\/early\/2022\/06\/16\/2022.06.14.22276401\/F1.large.jpg?width=800&amp;height=600&amp;carousel=1\" rel=\"gallery-fragment-images-1154678168\" data-figure-caption=\"&lt;div class=&quot;highwire-markup&quot;&gt;&lt;div xmlns=&quot;http:\/\/www.w3.org\/1999\/xhtml&quot;&gt;&lt;span class=&quot;caption-title&quot;&gt;SARS-CoV-2 antigen levels versus time.&lt;\/span&gt; The concentration of S1 &lt;strong&gt;(A)&lt;\/strong&gt;, spike &lt;strong&gt;(B)&lt;\/strong&gt;, and N &lt;strong&gt;(C)&lt;\/strong&gt; measured in the plasma of individuals over time after diagnosis with PASC or COVID-19 following SARS-CoV-2 infection. Multiple data points may correspond to the same individual, where repeat sampling was available. Data points represent mean values \u00b1 SD (n = 2). Dashed lines indicate the LOD for each assay.&lt;\/div&gt;&lt;\/div&gt;\" data-icon-position=\"\" data-hide-link-title=\"0\"><span class=\"hw-responsive-img\"><img loading=\"lazy\" decoding=\"async\" class=\"highwire-fragment fragment-image lazyloaded\" src=\"https:\/\/www.medrxiv.org\/content\/medrxiv\/early\/2022\/06\/16\/2022.06.14.22276401\/F1.medium.gif\" alt=\"\u03a6\u03b9\u03b3\u03bf\u03cd\u03c1\u03b1 1.\" width=\"440\" height=\"117\" data-src=\"https:\/\/www.medrxiv.org\/content\/medrxiv\/early\/2022\/06\/16\/2022.06.14.22276401\/F1.medium.gif\" \/><\/span><\/a><\/div>\n<\/div>\n<ul class=\"highwire-figure-links inline\">\n<li class=\"download-fig first\"><a class=\"highwire-figure-link highwire-figure-link-download\" title=\"\u039a\u03b1\u03c4\u03b5\u03b2\u03ac\u03c3\u03c4\u03b5 \u03c4\u03b7\u03bd \u03b5\u03b9\u03ba\u03cc\u03bd\u03b1 1.\" href=\"https:\/\/www.medrxiv.org\/content\/medrxiv\/early\/2022\/06\/16\/2022.06.14.22276401\/F1.large.jpg?download=true\" data-icon-position=\"\" data-hide-link-title=\"0\">\u039b\u03ae\u03c8\u03b7 \u03b5\u03b9\u03ba\u03cc\u03bd\u03b1\u03c2 <\/a><\/li>\n<li class=\"new-tab last\"><a class=\"highwire-figure-link highwire-figure-link-newtab\" href=\"https:\/\/www.medrxiv.org\/content\/medrxiv\/early\/2022\/06\/16\/2022.06.14.22276401\/F1.large.jpg\" target=\"_blank\" rel=\"noopener\" data-icon-position=\"\" data-hide-link-title=\"0\">\u0386\u03bd\u03bf\u03b9\u03b3\u03bc\u03b1 \u03c3\u03b5 \u03bd\u03ad\u03b1 \u03ba\u03b1\u03c1\u03c4\u03ad\u03bb\u03b1 <\/a><\/li>\n<\/ul>\n<\/div>\n<div class=\"fig-caption\">\n<p><span class=\"fig-label\">\u0395\u03b9\u03ba\u03cc\u03bd\u03b1 1. <\/span> <span class=\"caption-title\">\u0395\u03c0\u03af\u03c0\u03b5\u03b4\u03b1 \u03b1\u03bd\u03c4\u03b9\u03b3\u03cc\u03bd\u03bf\u03c5 SARS-CoV-2 \u03c3\u03b5 \u03c3\u03c5\u03bd\u03ac\u03c1\u03c4\u03b7\u03c3\u03b7 \u03bc\u03b5 \u03c4\u03bf \u03c7\u03c1\u03cc\u03bd\u03bf. <\/span><\/p>\n<p id=\"p-19\" class=\"first-child\">\u0397 \u03c3\u03c5\u03b3\u03ba\u03ad\u03bd\u03c4\u03c1\u03c9\u03c3\u03b7 \u03c4\u03bf\u03c5 S1 <strong>(A) <\/strong>, \u03c4\u03b7\u03c2 \u03b1\u03ba\u03af\u03b4\u03b1\u03c2 <strong>(B) <\/strong>\u03ba\u03b1\u03b9 \u03c4\u03bf\u03c5 N <strong>(C) <\/strong>\u03bc\u03b5\u03c4\u03c1\u03ae\u03b8\u03b7\u03ba\u03b5 \u03c3\u03c4\u03bf \u03c0\u03bb\u03ac\u03c3\u03bc\u03b1 \u03c4\u03c9\u03bd \u03b1\u03c4\u03cc\u03bc\u03c9\u03bd \u03bc\u03b5 \u03c4\u03b7\u03bd \u03c0\u03ac\u03c1\u03bf\u03b4\u03bf \u03c4\u03bf\u03c5 \u03c7\u03c1\u03cc\u03bd\u03bf\u03c5 \u03bc\u03b5\u03c4\u03ac \u03c4\u03b7 \u03b4\u03b9\u03ac\u03b3\u03bd\u03c9\u03c3\u03b7 \u03bc\u03b5 PASC \u03ae COVID-19 \u03bc\u03b5\u03c4\u03ac \u03b1\u03c0\u03cc \u03bc\u03cc\u03bb\u03c5\u03bd\u03c3\u03b7 \u03b1\u03c0\u03cc SARS-CoV-2. \u03a0\u03bf\u03bb\u03bb\u03ac \u03c3\u03b7\u03bc\u03b5\u03af\u03b1 \u03b4\u03b5\u03b4\u03bf\u03bc\u03ad\u03bd\u03c9\u03bd \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b1\u03bd\u03c4\u03b9\u03c3\u03c4\u03bf\u03b9\u03c7\u03bf\u03cd\u03bd \u03c3\u03c4\u03bf \u03af\u03b4\u03b9\u03bf \u03ac\u03c4\u03bf\u03bc\u03bf, \u03cc\u03c0\u03bf\u03c5 \u03ae\u03c4\u03b1\u03bd \u03b4\u03b9\u03b1\u03b8\u03ad\u03c3\u03b9\u03bc\u03b7 \u03b7 \u03b5\u03c0\u03b1\u03bd\u03b1\u03bb\u03b7\u03c0\u03c4\u03b9\u03ba\u03ae \u03b4\u03b5\u03b9\u03b3\u03bc\u03b1\u03c4\u03bf\u03bb\u03b7\u03c8\u03af\u03b1. \u03a4\u03b1 \u03c3\u03b7\u03bc\u03b5\u03af\u03b1 \u03b4\u03b5\u03b4\u03bf\u03bc\u03ad\u03bd\u03c9\u03bd \u03b1\u03bd\u03c4\u03b9\u03c0\u03c1\u03bf\u03c3\u03c9\u03c0\u03b5\u03cd\u03bf\u03c5\u03bd \u03bc\u03ad\u03c3\u03b5\u03c2 \u03c4\u03b9\u03bc\u03ad\u03c2 \u00b1 SD (n = 2). \u039f\u03b9 \u03b4\u03b9\u03b1\u03ba\u03b5\u03ba\u03bf\u03bc\u03bc\u03ad\u03bd\u03b5\u03c2 \u03b3\u03c1\u03b1\u03bc\u03bc\u03ad\u03c2 \u03c5\u03c0\u03bf\u03b4\u03b5\u03b9\u03ba\u03bd\u03cd\u03bf\u03c5\u03bd \u03c4\u03bf LOD \u03b3\u03b9\u03b1 \u03ba\u03ac\u03b8\u03b5 \u03c0\u03c1\u03bf\u03c3\u03b4\u03b9\u03bf\u03c1\u03b9\u03c3\u03bc\u03cc.<\/p>\n<div class=\"sb-div caption-clear\"><\/div>\n<\/div>\n<\/div>\n<p id=\"p-20\">\u0388\u03bd\u03b1\u03c2 \u03b1\u03c1\u03b9\u03b8\u03bc\u03cc\u03c2 \u03b1\u03c3\u03b8\u03b5\u03bd\u03ce\u03bd \u03bc\u03b5 PASC \u03ba\u03b1\u03b9 \u03ad\u03bd\u03b1 \u03c5\u03c0\u03bf\u03c3\u03cd\u03bd\u03bf\u03bb\u03bf \u03b4\u03b5\u03b9\u03b3\u03bc\u03ac\u03c4\u03c9\u03bd \u03b1\u03af\u03bc\u03b1\u03c4\u03bf\u03c2 \u03b1\u03c3\u03b8\u03b5\u03bd\u03ce\u03bd \u03bc\u03b5 COVID-19 \u03c3\u03c5\u03bb\u03bb\u03ad\u03c7\u03b8\u03b7\u03ba\u03b1\u03bd \u03c3\u03b5 \u03c0\u03bf\u03bb\u03bb\u03b1\u03c0\u03bb\u03ac \u03c7\u03c1\u03bf\u03bd\u03b9\u03ba\u03ac \u03c3\u03b7\u03bc\u03b5\u03af\u03b1, \u03b5\u03c0\u03b9\u03c4\u03c1\u03ad\u03c0\u03bf\u03bd\u03c4\u03ac\u03c2 \u03bc\u03b1\u03c2 \u03bd\u03b1 \u03b1\u03bd\u03b1\u03bb\u03cd\u03c3\u03bf\u03c5\u03bc\u03b5 \u03c4\u03b7\u03bd \u03b1\u03bb\u03bb\u03b1\u03b3\u03ae \u03c3\u03c4\u03b1 \u03b5\u03c0\u03af\u03c0\u03b5\u03b4\u03b1 \u03b1\u03bd\u03c4\u03b9\u03b3\u03cc\u03bd\u03bf\u03c5 \u03bc\u03b5 \u03c4\u03b7\u03bd \u03c0\u03ac\u03c1\u03bf\u03b4\u03bf \u03c4\u03bf\u03c5 \u03c7\u03c1\u03cc\u03bd\u03bf\u03c5. \u0391\u03c0\u03cc \u03c4\u03bf\u03c5\u03c2 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 PASC \u03b3\u03b9\u03b1 \u03c4\u03bf\u03c5\u03c2 \u03bf\u03c0\u03bf\u03af\u03bf\u03c5\u03c2 \u03b5\u03af\u03c7\u03b1\u03bc\u03b5 \u03b4\u03b9\u03b1\u03bc\u03ae\u03ba\u03b7 \u03b4\u03b5\u03af\u03b3\u03bc\u03b1\u03c4\u03b1, \u03b5\u03bd\u03c4\u03bf\u03c0\u03af\u03c3\u03b1\u03bc\u03b5 \u03b1\u03bd\u03c4\u03b9\u03b3\u03cc\u03bd\u03bf \u03c0\u03b5\u03c1\u03b9\u03c3\u03c3\u03cc\u03c4\u03b5\u03c1\u03b5\u03c2 \u03b1\u03c0\u03cc \u03bc\u03af\u03b1 \u03c6\u03bf\u03c1\u03ad\u03c2 \u03c3\u03b5 12 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2, \u03b5\u03bd\u03b9\u03c3\u03c7\u03cd\u03bf\u03bd\u03c4\u03b1\u03c2 \u03c4\u03b7\u03bd \u03b5\u03c0\u03af\u03bc\u03bf\u03bd\u03b7 \u03c0\u03b1\u03c1\u03bf\u03c5\u03c3\u03af\u03b1 \u03c4\u03bf\u03c5 \u03ba\u03c5\u03ba\u03bb\u03bf\u03c6\u03bf\u03c1\u03bf\u03cd\u03bd\u03c4\u03bf\u03c2 \u03b1\u03bd\u03c4\u03b9\u03b3\u03cc\u03bd\u03bf\u03c5 ( <a id=\"xref-fig-2-1\" class=\"xref-fig\" href=\"https:\/\/www.medrxiv.org\/content\/10.1101\/2022.06.14.22276401v1.full#F2\">\u0395\u03b9\u03ba\u03cc\u03bd\u03b1 2 <\/a>). <strong>\u03a3\u03b5 \u03bb\u03af\u03b3\u03b5\u03c2 \u03bc\u03cc\u03bd\u03bf \u03c0\u03b5\u03c1\u03b9\u03c0\u03c4\u03ce\u03c3\u03b5\u03b9\u03c2, \u03b7 \u03c0\u03b1\u03c1\u03bf\u03c5\u03c3\u03af\u03b1 \u03c4\u03bf\u03c5 S1 \u03ae \u03c4\u03b7\u03c2 \u03b1\u03ba\u03af\u03b4\u03b1\u03c2 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03c3\u03c5\u03c3\u03c7\u03b5\u03c4\u03b9\u03c3\u03c4\u03b5\u03af \u03bc\u03b5 \u03c4\u03bf\u03bd \u03b5\u03bc\u03b2\u03bf\u03bb\u03b9\u03b1\u03c3\u03bc\u03cc, \u03c9\u03c3\u03c4\u03cc\u03c3\u03bf \u03c3\u03cd\u03bc\u03c6\u03c9\u03bd\u03b1 \u03bc\u03b5 \u03c4\u03b1 \u03c0\u03c1\u03bf\u03b7\u03b3\u03bf\u03cd\u03bc\u03b5\u03bd\u03b1 \u03b5\u03c5\u03c1\u03ae\u03bc\u03b1\u03c4\u03ac \u03bc\u03b1\u03c2, \u03c4\u03bf S1 \u03b1\u03bd\u03b9\u03c7\u03bd\u03b5\u03cd\u03b5\u03c4\u03b1\u03b9 \u03bc\u03cc\u03bd\u03bf \u03b5\u03bd\u03c4\u03cc\u03c2 \u03c4\u03c9\u03bd \u03b4\u03cd\u03bf \u03c0\u03c1\u03ce\u03c4\u03c9\u03bd \u03b5\u03b2\u03b4\u03bf\u03bc\u03ac\u03b4\u03c9\u03bd \u03bc\u03b5\u03c4\u03ac \u03c4\u03b7\u03bd \u03c0\u03c1\u03ce\u03c4\u03b7 \u03b4\u03cc\u03c3\u03b7 \u03ba\u03b1\u03b9 \u03c3\u03c0\u03ac\u03bd\u03b9\u03b1 \u03b1\u03bd\u03b9\u03c7\u03bd\u03b5\u03cd\u03b5\u03c4\u03b1\u03b9 \u03b1\u03ba\u03af\u03b4\u03b1. <\/strong><strong><sup><a id=\"xref-ref-20-1\" class=\"xref-bibr\" href=\"https:\/\/www.medrxiv.org\/content\/10.1101\/2022.06.14.22276401v1.full#ref-20\">20 <\/a><\/sup><\/strong><strong>\u03a4\u03bf \u03c0\u03b9\u03bf \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03cc \u03b5\u03af\u03bd\u03b1\u03b9 \u03cc\u03c4\u03b9 \u03c0\u03b1\u03c1\u03b1\u03c4\u03b7\u03c1\u03bf\u03cd\u03bc\u03b5 \u03bc\u03bf\u03c4\u03af\u03b2\u03b1 \u03c0\u03b1\u03c1\u03b1\u03c4\u03b5\u03c4\u03b1\u03bc\u03ad\u03bd\u03c9\u03bd \u03b5\u03c0\u03b9\u03c0\u03ad\u03b4\u03c9\u03bd \u03b1\u03bd\u03c4\u03b9\u03b3\u03cc\u03bd\u03bf\u03c5 \u03c0\u03bb\u03ae\u03c1\u03bf\u03c5\u03c2 \u03b1\u03b9\u03c7\u03bc\u03ae\u03c2 \u03ba\u03b1\u03c4\u03ac \u03c4\u03b7 \u03b4\u03b9\u03ac\u03c1\u03ba\u03b5\u03b9\u03b1 \u03b1\u03c1\u03ba\u03b5\u03c4\u03ce\u03bd \u03bc\u03b7\u03bd\u03ce\u03bd \u03c3\u03b5 \u03c0\u03bf\u03bb\u03bb\u03bf\u03cd\u03c2 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2.<\/strong> \u03a3\u03b5 \u03ac\u03bb\u03bb\u03b5\u03c2 \u03c0\u03b5\u03c1\u03b9\u03c0\u03c4\u03ce\u03c3\u03b5\u03b9\u03c2, \u03c0\u03b1\u03c1\u03b1\u03c4\u03b7\u03c1\u03bf\u03cd\u03bc\u03b5 \u03b4\u03b9\u03b1\u03ba\u03c5\u03bc\u03ac\u03bd\u03c3\u03b5\u03b9\u03c2 \u03bc\u03b5\u03c4\u03b1\u03be\u03cd \u03c4\u03bf\u03c5 \u03b1\u03bd\u03c4\u03b9\u03b3\u03cc\u03bd\u03bf\u03c5 \u03c0\u03bf\u03c5 \u03b1\u03bd\u03b9\u03c7\u03bd\u03b5\u03cd\u03b5\u03c4\u03b1\u03b9 \u03ba\u03b1\u03b9 \u03b4\u03b5\u03bd \u03b1\u03bd\u03b9\u03c7\u03bd\u03b5\u03cd\u03b5\u03c4\u03b1\u03b9, \u03c5\u03c0\u03bf\u03b4\u03b5\u03b9\u03ba\u03bd\u03cd\u03bf\u03bd\u03c4\u03b1\u03c2 \u03cc\u03c4\u03b9 \u03bf \u03c7\u03c1\u03cc\u03bd\u03bf\u03c2 \u03b4\u03b5\u03b9\u03b3\u03bc\u03b1\u03c4\u03bf\u03bb\u03b7\u03c8\u03af\u03b1\u03c2 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03cc\u03c2. \u0391\u03bd\u03c4\u03af\u03b8\u03b5\u03c4\u03b1, \u03c4\u03b1 \u03c7\u03c1\u03bf\u03bd\u03b9\u03ba\u03ac \u03c0\u03c1\u03bf\u03c6\u03af\u03bb \u03b1\u03bd\u03c4\u03b9\u03b3\u03cc\u03bd\u03bf\u03c5 \u03ad\u03be\u03b9 \u03b1\u03c3\u03b8\u03b5\u03bd\u03ce\u03bd \u03bc\u03b5 COVID-19 \u03b4\u03b5\u03af\u03c7\u03bd\u03bf\u03c5\u03bd \u03c5\u03c8\u03b7\u03bb\u03ac \u03b5\u03c0\u03af\u03c0\u03b5\u03b4\u03b1 \u03b1\u03bd\u03c4\u03b9\u03b3\u03cc\u03bd\u03bf\u03c5 \u03b1\u03bc\u03ad\u03c3\u03c9\u03c2 \u03bc\u03b5\u03c4\u03ac \u03c4\u03b7 \u03b4\u03b9\u03ac\u03b3\u03bd\u03c9\u03c3\u03b7, \u03c0\u03ad\u03c6\u03c4\u03bf\u03bd\u03c4\u03b1\u03c2 \u03b3\u03c1\u03ae\u03b3\u03bf\u03c1\u03b1 \u03ba\u03ac\u03c4\u03c9 \u03b1\u03c0\u03cc \u03c4\u03bf \u03cc\u03c1\u03b9\u03bf \u03b1\u03bd\u03af\u03c7\u03bd\u03b5\u03c5\u03c3\u03b7\u03c2 ( <a id=\"xref-fig-3-1\" class=\"xref-fig\" href=\"https:\/\/www.medrxiv.org\/content\/10.1101\/2022.06.14.22276401v1.full#F3\">\u0395\u03b9\u03ba\u03cc\u03bd\u03b1 S1 <\/a>).<\/p>\n<div id=\"F3\" class=\"fig pos-float type-figure odd\">\n<div class=\"highwire-figure\">\n<div class=\"fig-inline-img-wrapper\">\n<div class=\"fig-inline-img\"><a class=\"highwire-fragment fragment-images colorbox-load highwireFiguresMarkupProcessor-processed cboxElement\" title=\"\u03a7\u03c1\u03bf\u03bd\u03b9\u03ba\u03cc \u03c0\u03c1\u03bf\u03c6\u03af\u03bb \u03c4\u03c9\u03bd \u03b1\u03bd\u03c4\u03b9\u03b3\u03cc\u03bd\u03c9\u03bd SARS-CoV-2 \u03b3\u03b9\u03b1 \u03bc\u03b5\u03bc\u03bf\u03bd\u03c9\u03bc\u03ad\u03bd\u03bf\u03c5\u03c2 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 COVID-19. \u0395\u03c0\u03af\u03c0\u03b5\u03b4\u03b1 S1, \u03b1\u03ba\u03af\u03b4\u03b1 \u03ba\u03b1\u03b9 \u039d \u03ad\u03bd\u03b1\u03bd\u03c4\u03b9 \u03c4\u03bf\u03c5 \u03c7\u03c1\u03cc\u03bd\u03bf\u03c5 \u03b3\u03b9\u03b1 \u03ad\u03be\u03b9 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 COVID-19 \u03c0\u03bf\u03c5 \u03b4\u03b9\u03b1\u03b3\u03bd\u03ce\u03c3\u03c4\u03b7\u03ba\u03b1\u03bd \u03bc\u03b5 PASC. \u03a4\u03b1 \u03c3\u03b7\u03bc\u03b5\u03af\u03b1 \u03b4\u03b5\u03b4\u03bf\u03bc\u03ad\u03bd\u03c9\u03bd \u03b1\u03bd\u03c4\u03b9\u03c0\u03c1\u03bf\u03c3\u03c9\u03c0\u03b5\u03cd\u03bf\u03c5\u03bd \u03bc\u03ad\u03c3\u03b5\u03c2 \u03c4\u03b9\u03bc\u03ad\u03c2 \u00b1 SD (n = 2). \u039f\u03b9 \u03b4\u03b9\u03b1\u03ba\u03b5\u03ba\u03bf\u03bc\u03bc\u03ad\u03bd\u03b5\u03c2 \u03bf\u03c1\u03b9\u03b6\u03cc\u03bd\u03c4\u03b9\u03b5\u03c2 \u03b3\u03c1\u03b1\u03bc\u03bc\u03ad\u03c2 \u03c5\u03c0\u03bf\u03b4\u03b5\u03b9\u03ba\u03bd\u03cd\u03bf\u03c5\u03bd \u03c4\u03bf LOD \u03b3\u03b9\u03b1 \u03ba\u03ac\u03b8\u03b5 \u03c0\u03c1\u03bf\u03c3\u03b4\u03b9\u03bf\u03c1\u03b9\u03c3\u03bc\u03cc.\" href=\"https:\/\/www.medrxiv.org\/content\/medrxiv\/early\/2022\/06\/16\/2022.06.14.22276401\/F3.large.jpg?width=800&amp;height=600&amp;carousel=1\" rel=\"gallery-fragment-images-1154678168\" data-figure-caption=\"&lt;div class=&quot;highwire-markup&quot;&gt;&lt;span xmlns=&quot;http:\/\/www.w3.org\/1999\/xhtml&quot; class=&quot;caption-title&quot;&gt;Temporal profiling of SARS-CoV-2 antigens for individual COVID-19 patients.&lt;\/span&gt; S1, spike, and N levels versus time for six COVID-19 patients diagnosed with PASC. Data points represent mean values \u00b1 SD (n = 2). Dashed horizontal lines indicate the LOD for each assay.&lt;\/div&gt;\" data-icon-position=\"\" data-hide-link-title=\"0\"><span class=\"hw-responsive-img\"><img loading=\"lazy\" decoding=\"async\" class=\"highwire-fragment fragment-image lazyloaded\" src=\"https:\/\/www.medrxiv.org\/content\/medrxiv\/early\/2022\/06\/16\/2022.06.14.22276401\/F3.medium.gif\" alt=\"\u0395\u03b9\u03ba\u03cc\u03bd\u03b1 S1.\" width=\"654\" height=\"367\" data-src=\"https:\/\/www.medrxiv.org\/content\/medrxiv\/early\/2022\/06\/16\/2022.06.14.22276401\/F3.medium.gif\" \/><\/span><\/a><\/div>\n<\/div>\n<ul class=\"highwire-figure-links inline\">\n<li class=\"download-fig first\"><a class=\"highwire-figure-link highwire-figure-link-download\" title=\"\u039a\u03b1\u03c4\u03b5\u03b2\u03ac\u03c3\u03c4\u03b5 \u03c4\u03bf \u03a3\u03c7\u03ae\u03bc\u03b1 S1.\" href=\"https:\/\/www.medrxiv.org\/content\/medrxiv\/early\/2022\/06\/16\/2022.06.14.22276401\/F3.large.jpg?download=true\" data-icon-position=\"\" data-hide-link-title=\"0\">\u039b\u03ae\u03c8\u03b7 \u03b5\u03b9\u03ba\u03cc\u03bd\u03b1\u03c2 <\/a><\/li>\n<li class=\"new-tab last\"><a class=\"highwire-figure-link highwire-figure-link-newtab\" href=\"https:\/\/www.medrxiv.org\/content\/medrxiv\/early\/2022\/06\/16\/2022.06.14.22276401\/F3.large.jpg\" target=\"_blank\" rel=\"noopener\" data-icon-position=\"\" data-hide-link-title=\"0\">\u0386\u03bd\u03bf\u03b9\u03b3\u03bc\u03b1 \u03c3\u03b5 \u03bd\u03ad\u03b1 \u03ba\u03b1\u03c1\u03c4\u03ad\u03bb\u03b1 <\/a><\/li>\n<\/ul>\n<\/div>\n<div class=\"fig-caption\">\n<p><span class=\"fig-label\">\u0395\u03b9\u03ba\u03cc\u03bd\u03b1 S1. <\/span> <span class=\"caption-title\">\u03a7\u03c1\u03bf\u03bd\u03b9\u03ba\u03cc \u03c0\u03c1\u03bf\u03c6\u03af\u03bb \u03c4\u03c9\u03bd \u03b1\u03bd\u03c4\u03b9\u03b3\u03cc\u03bd\u03c9\u03bd SARS-CoV-2 \u03b3\u03b9\u03b1 \u03bc\u03b5\u03bc\u03bf\u03bd\u03c9\u03bc\u03ad\u03bd\u03bf\u03c5\u03c2 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 COVID-19. <\/span><\/p>\n<p id=\"p-35\" class=\"first-child\">\u0395\u03c0\u03af\u03c0\u03b5\u03b4\u03b1 S1, \u03b1\u03ba\u03af\u03b4\u03b1 \u03ba\u03b1\u03b9 \u039d \u03ad\u03bd\u03b1\u03bd\u03c4\u03b9 \u03c4\u03bf\u03c5 \u03c7\u03c1\u03cc\u03bd\u03bf\u03c5 \u03b3\u03b9\u03b1 \u03ad\u03be\u03b9 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 COVID-19 \u03c0\u03bf\u03c5 \u03b4\u03b9\u03b1\u03b3\u03bd\u03ce\u03c3\u03c4\u03b7\u03ba\u03b1\u03bd \u03bc\u03b5 PASC. \u03a4\u03b1 \u03c3\u03b7\u03bc\u03b5\u03af\u03b1 \u03b4\u03b5\u03b4\u03bf\u03bc\u03ad\u03bd\u03c9\u03bd \u03b1\u03bd\u03c4\u03b9\u03c0\u03c1\u03bf\u03c3\u03c9\u03c0\u03b5\u03cd\u03bf\u03c5\u03bd \u03bc\u03ad\u03c3\u03b5\u03c2 \u03c4\u03b9\u03bc\u03ad\u03c2 \u00b1 SD (n = 2). \u039f\u03b9 \u03b4\u03b9\u03b1\u03ba\u03b5\u03ba\u03bf\u03bc\u03bc\u03ad\u03bd\u03b5\u03c2 \u03bf\u03c1\u03b9\u03b6\u03cc\u03bd\u03c4\u03b9\u03b5\u03c2 \u03b3\u03c1\u03b1\u03bc\u03bc\u03ad\u03c2 \u03c5\u03c0\u03bf\u03b4\u03b5\u03b9\u03ba\u03bd\u03cd\u03bf\u03c5\u03bd \u03c4\u03bf LOD \u03b3\u03b9\u03b1 \u03ba\u03ac\u03b8\u03b5 \u03c0\u03c1\u03bf\u03c3\u03b4\u03b9\u03bf\u03c1\u03b9\u03c3\u03bc\u03cc.<\/p>\n<div class=\"sb-div caption-clear\"><\/div>\n<\/div>\n<\/div>\n<div id=\"F2\" class=\"fig pos-float type-figure odd\">\n<div class=\"highwire-figure\">\n<div class=\"fig-inline-img-wrapper\">\n<div class=\"fig-inline-img\"><a class=\"highwire-fragment fragment-images colorbox-load highwireFiguresMarkupProcessor-processed cboxElement\" title=\"\u03a7\u03c1\u03bf\u03bd\u03b9\u03ba\u03cc \u03c0\u03c1\u03bf\u03c6\u03af\u03bb \u03c4\u03c9\u03bd \u03b1\u03bd\u03c4\u03b9\u03b3\u03cc\u03bd\u03c9\u03bd SARS-CoV-2 \u03b3\u03b9\u03b1 \u03bc\u03b5\u03bc\u03bf\u03bd\u03c9\u03bc\u03ad\u03bd\u03bf\u03c5\u03c2 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 PASC. \u0395\u03c0\u03af\u03c0\u03b5\u03b4\u03b1 S1, \u03b1\u03ba\u03af\u03b4\u03b1 \u03ba\u03b1\u03b9 \u039d \u03ad\u03bd\u03b1\u03bd\u03c4\u03b9 \u03c4\u03bf\u03c5 \u03c7\u03c1\u03cc\u03bd\u03bf\u03c5 \u03b3\u03b9\u03b1 12 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03c0\u03bf\u03c5 \u03b4\u03b9\u03b1\u03b3\u03bd\u03ce\u03c3\u03c4\u03b7\u03ba\u03b1\u03bd \u03bc\u03b5 PASC. \u03a4\u03b1 \u03c3\u03b7\u03bc\u03b5\u03af\u03b1 \u03b4\u03b5\u03b4\u03bf\u03bc\u03ad\u03bd\u03c9\u03bd \u03b1\u03bd\u03c4\u03b9\u03c0\u03c1\u03bf\u03c3\u03c9\u03c0\u03b5\u03cd\u03bf\u03c5\u03bd \u03bc\u03ad\u03c3\u03b5\u03c2 \u03c4\u03b9\u03bc\u03ad\u03c2 \u00b1 SD (n = 2). \u039f\u03b9 \u03b3\u03ba\u03c1\u03af\u03b6\u03b5\u03c2 \u03ba\u03ac\u03b8\u03b5\u03c4\u03b5\u03c2 \u03b3\u03c1\u03b1\u03bc\u03bc\u03ad\u03c2 \u03b1\u03bd\u03c4\u03b9\u03c3\u03c4\u03bf\u03b9\u03c7\u03bf\u03cd\u03bd \u03c3\u03c4\u03bf\u03c5\u03c2 \u03c7\u03c1\u03cc\u03bd\u03bf\u03c5\u03c2 \u03c0\u03bf\u03c5 \u03ba\u03ac\u03b8\u03b5 \u03b1\u03c3\u03b8\u03b5\u03bd\u03ae\u03c2 \u03ad\u03bb\u03b1\u03b2\u03b5 \u03b5\u03af\u03c4\u03b5 \u03c4\u03b7\u03bd \u03c0\u03c1\u03ce\u03c4\u03b7, \u03c4\u03b7 \u03b4\u03b5\u03cd\u03c4\u03b5\u03c1\u03b7 \u03ae \u03c4\u03b7\u03bd \u03c4\u03c1\u03af\u03c4\u03b7 \u03b4\u03cc\u03c3\u03b7 \u03b5\u03bc\u03b2\u03bf\u03bb\u03af\u03bf\u03c5 \u03b3\u03b9\u03b1 \u03c4\u03bf\u03bd COVID-19. \u0395\u03ac\u03bd \u03ad\u03bd\u03b1 \u03ac\u03c4\u03bf\u03bc\u03bf \u03b4\u03b5\u03bd \u03b5\u03bc\u03b2\u03bf\u03bb\u03b9\u03ac\u03c3\u03c4\u03b7\u03ba\u03b5 \u03b5\u03bd\u03c4\u03cc\u03c2 \u03b5\u03bd\u03cc\u03c2 \u03bc\u03ae\u03bd\u03b1 \u03b1\u03c0\u03cc \u03c4\u03bf \u03c7\u03c1\u03bf\u03bd\u03b9\u03ba\u03cc \u03c0\u03bb\u03b1\u03af\u03c3\u03b9\u03bf \u03c0\u03bf\u03c5 \u03b5\u03bc\u03c6\u03b1\u03bd\u03af\u03b6\u03b5\u03c4\u03b1\u03b9, \u03b4\u03b5\u03bd \u03b5\u03bc\u03c6\u03b1\u03bd\u03af\u03b6\u03bf\u03bd\u03c4\u03b1\u03b9 \u03c0\u03bb\u03b7\u03c1\u03bf\u03c6\u03bf\u03c1\u03af\u03b5\u03c2 \u03b5\u03bc\u03b2\u03bf\u03bb\u03b9\u03b1\u03c3\u03bc\u03bf\u03cd. \u039f\u03b9 \u03b4\u03b9\u03b1\u03ba\u03b5\u03ba\u03bf\u03bc\u03bc\u03ad\u03bd\u03b5\u03c2 \u03bf\u03c1\u03b9\u03b6\u03cc\u03bd\u03c4\u03b9\u03b5\u03c2 \u03b3\u03c1\u03b1\u03bc\u03bc\u03ad\u03c2 \u03c5\u03c0\u03bf\u03b4\u03b5\u03b9\u03ba\u03bd\u03cd\u03bf\u03c5\u03bd \u03c4\u03bf LOD \u03b3\u03b9\u03b1 \u03ba\u03ac\u03b8\u03b5 \u03c0\u03c1\u03bf\u03c3\u03b4\u03b9\u03bf\u03c1\u03b9\u03c3\u03bc\u03cc.\" href=\"https:\/\/www.medrxiv.org\/content\/medrxiv\/early\/2022\/06\/16\/2022.06.14.22276401\/F2.large.jpg?width=800&amp;height=600&amp;carousel=1\" rel=\"gallery-fragment-images-1154678168\" data-figure-caption=\"&lt;div class=&quot;highwire-markup&quot;&gt;&lt;span xmlns=&quot;http:\/\/www.w3.org\/1999\/xhtml&quot; class=&quot;caption-title&quot;&gt;Temporal profiling of SARS-CoV-2 antigens for individual PASC patients.&lt;\/span&gt; S1, spike, and N levels versus time for 12 patients diagnosed with PASC. Data points represent mean values \u00b1 SD (n = 2). Grey vertical lines correspond to the times when each patient received either the first, second or third dose of a COVID-19 vaccine. If an individual was not vaccinated within one month of the time frame shown, no vaccination information is shown. Dashed horizontal lines indicate the LOD for each assay.&lt;\/div&gt;\" data-icon-position=\"\" data-hide-link-title=\"0\"><span class=\"hw-responsive-img\"><img loading=\"lazy\" decoding=\"async\" class=\"highwire-fragment fragment-image lazyloaded\" src=\"https:\/\/www.medrxiv.org\/content\/medrxiv\/early\/2022\/06\/16\/2022.06.14.22276401\/F2.medium.gif\" alt=\"\u03a3\u03c7\u03ae\u03bc\u03b1 2.\" width=\"670\" height=\"452\" data-src=\"https:\/\/www.medrxiv.org\/content\/medrxiv\/early\/2022\/06\/16\/2022.06.14.22276401\/F2.medium.gif\" \/><\/span><\/a><\/div>\n<\/div>\n<ul class=\"highwire-figure-links inline\">\n<li class=\"download-fig first\"><a class=\"highwire-figure-link highwire-figure-link-download\" title=\"\u039a\u03b1\u03c4\u03b5\u03b2\u03ac\u03c3\u03c4\u03b5 \u03c4\u03b7\u03bd \u0395\u03b9\u03ba\u03cc\u03bd\u03b1 2.\" href=\"https:\/\/www.medrxiv.org\/content\/medrxiv\/early\/2022\/06\/16\/2022.06.14.22276401\/F2.large.jpg?download=true\" data-icon-position=\"\" data-hide-link-title=\"0\">\u039b\u03ae\u03c8\u03b7 \u03b5\u03b9\u03ba\u03cc\u03bd\u03b1\u03c2 <\/a><\/li>\n<li class=\"new-tab last\"><a class=\"highwire-figure-link highwire-figure-link-newtab\" href=\"https:\/\/www.medrxiv.org\/content\/medrxiv\/early\/2022\/06\/16\/2022.06.14.22276401\/F2.large.jpg\" target=\"_blank\" rel=\"noopener\" data-icon-position=\"\" data-hide-link-title=\"0\">\u0386\u03bd\u03bf\u03b9\u03b3\u03bc\u03b1 \u03c3\u03b5 \u03bd\u03ad\u03b1 \u03ba\u03b1\u03c1\u03c4\u03ad\u03bb\u03b1 <\/a><\/li>\n<\/ul>\n<\/div>\n<div class=\"fig-caption\">\n<p><span class=\"fig-label\">\u0395\u03b9\u03ba\u03cc\u03bd\u03b1 2. <\/span> <span class=\"caption-title\">\u03a7\u03c1\u03bf\u03bd\u03b9\u03ba\u03cc \u03c0\u03c1\u03bf\u03c6\u03af\u03bb \u03c4\u03c9\u03bd \u03b1\u03bd\u03c4\u03b9\u03b3\u03cc\u03bd\u03c9\u03bd SARS-CoV-2 \u03b3\u03b9\u03b1 \u03bc\u03b5\u03bc\u03bf\u03bd\u03c9\u03bc\u03ad\u03bd\u03bf\u03c5\u03c2 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 PASC. <\/span><\/p>\n<p id=\"p-21\" class=\"first-child\">\u0395\u03c0\u03af\u03c0\u03b5\u03b4\u03b1 S1, \u03b1\u03ba\u03af\u03b4\u03b1 \u03ba\u03b1\u03b9 \u039d \u03ad\u03bd\u03b1\u03bd\u03c4\u03b9 \u03c4\u03bf\u03c5 \u03c7\u03c1\u03cc\u03bd\u03bf\u03c5 \u03b3\u03b9\u03b1 12 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03c0\u03bf\u03c5 \u03b4\u03b9\u03b1\u03b3\u03bd\u03ce\u03c3\u03c4\u03b7\u03ba\u03b1\u03bd \u03bc\u03b5 PASC. \u03a4\u03b1 \u03c3\u03b7\u03bc\u03b5\u03af\u03b1 \u03b4\u03b5\u03b4\u03bf\u03bc\u03ad\u03bd\u03c9\u03bd \u03b1\u03bd\u03c4\u03b9\u03c0\u03c1\u03bf\u03c3\u03c9\u03c0\u03b5\u03cd\u03bf\u03c5\u03bd \u03bc\u03ad\u03c3\u03b5\u03c2 \u03c4\u03b9\u03bc\u03ad\u03c2 \u00b1 SD (n = 2). \u039f\u03b9 \u03b3\u03ba\u03c1\u03af\u03b6\u03b5\u03c2 \u03ba\u03ac\u03b8\u03b5\u03c4\u03b5\u03c2 \u03b3\u03c1\u03b1\u03bc\u03bc\u03ad\u03c2 \u03b1\u03bd\u03c4\u03b9\u03c3\u03c4\u03bf\u03b9\u03c7\u03bf\u03cd\u03bd \u03c3\u03c4\u03bf\u03c5\u03c2 \u03c7\u03c1\u03cc\u03bd\u03bf\u03c5\u03c2 \u03c0\u03bf\u03c5 \u03ba\u03ac\u03b8\u03b5 \u03b1\u03c3\u03b8\u03b5\u03bd\u03ae\u03c2 \u03ad\u03bb\u03b1\u03b2\u03b5 \u03b5\u03af\u03c4\u03b5 \u03c4\u03b7\u03bd \u03c0\u03c1\u03ce\u03c4\u03b7, \u03c4\u03b7 \u03b4\u03b5\u03cd\u03c4\u03b5\u03c1\u03b7 \u03ae \u03c4\u03b7\u03bd \u03c4\u03c1\u03af\u03c4\u03b7 \u03b4\u03cc\u03c3\u03b7 \u03b5\u03bc\u03b2\u03bf\u03bb\u03af\u03bf\u03c5 \u03b3\u03b9\u03b1 \u03c4\u03bf\u03bd COVID-19. \u0395\u03ac\u03bd \u03ad\u03bd\u03b1 \u03ac\u03c4\u03bf\u03bc\u03bf \u03b4\u03b5\u03bd \u03b5\u03bc\u03b2\u03bf\u03bb\u03b9\u03ac\u03c3\u03c4\u03b7\u03ba\u03b5 \u03b5\u03bd\u03c4\u03cc\u03c2 \u03b5\u03bd\u03cc\u03c2 \u03bc\u03ae\u03bd\u03b1 \u03b1\u03c0\u03cc \u03c4\u03bf \u03c7\u03c1\u03bf\u03bd\u03b9\u03ba\u03cc \u03c0\u03bb\u03b1\u03af\u03c3\u03b9\u03bf \u03c0\u03bf\u03c5 \u03b5\u03bc\u03c6\u03b1\u03bd\u03af\u03b6\u03b5\u03c4\u03b1\u03b9, \u03b4\u03b5\u03bd \u03b5\u03bc\u03c6\u03b1\u03bd\u03af\u03b6\u03bf\u03bd\u03c4\u03b1\u03b9 \u03c0\u03bb\u03b7\u03c1\u03bf\u03c6\u03bf\u03c1\u03af\u03b5\u03c2 \u03b5\u03bc\u03b2\u03bf\u03bb\u03b9\u03b1\u03c3\u03bc\u03bf\u03cd. \u039f\u03b9 \u03b4\u03b9\u03b1\u03ba\u03b5\u03ba\u03bf\u03bc\u03bc\u03ad\u03bd\u03b5\u03c2 \u03bf\u03c1\u03b9\u03b6\u03cc\u03bd\u03c4\u03b9\u03b5\u03c2 \u03b3\u03c1\u03b1\u03bc\u03bc\u03ad\u03c2 \u03c5\u03c0\u03bf\u03b4\u03b5\u03b9\u03ba\u03bd\u03cd\u03bf\u03c5\u03bd \u03c4\u03bf LOD \u03b3\u03b9\u03b1 \u03ba\u03ac\u03b8\u03b5 \u03c0\u03c1\u03bf\u03c3\u03b4\u03b9\u03bf\u03c1\u03b9\u03c3\u03bc\u03cc.<\/p>\n<div class=\"sb-div caption-clear\"><\/div>\n<\/div>\n<\/div>\n<p id=\"p-22\">\u039c\u03b5\u03c4\u03c1\u03ae\u03c3\u03b1\u03bc\u03b5 \u03b5\u03c0\u03af\u03c3\u03b7\u03c2 \u03c4\u03b9\u03c2 \u03c3\u03c5\u03b3\u03ba\u03b5\u03bd\u03c4\u03c1\u03ce\u03c3\u03b5\u03b9\u03c2 \u03c3\u03c4\u03bf \u03c0\u03bb\u03ac\u03c3\u03bc\u03b1 \u03bc\u03b9\u03b1\u03c2 \u03bf\u03bc\u03ac\u03b4\u03b1\u03c2 \u03ba\u03c5\u03c4\u03bf\u03ba\u03b9\u03bd\u03ce\u03bd, \u03c3\u03c5\u03bc\u03c0\u03b5\u03c1\u03b9\u03bb\u03b1\u03bc\u03b2\u03b1\u03bd\u03bf\u03bc\u03ad\u03bd\u03c9\u03bd \u03c4\u03c9\u03bd IFN-\u03b3, IL-1\u03b2, IL-4, IL-5, IL-6, IL-8, IL-10, IL-12p70, IL-22 \u03ba\u03b1\u03b9 TNF-\u237a, \u03b1\u03bb\u03bb\u03ac \u03b4\u03b5\u03bd \u03c5\u03c0\u03ae\u03c1\u03c7\u03b1\u03bd \u03c3\u03b1\u03c6\u03ae \u03b5\u03c5\u03c1\u03ae\u03bc\u03b1\u03c4\u03b1 ( <a id=\"xref-fig-4-1\" class=\"xref-fig\" href=\"https:\/\/www.medrxiv.org\/content\/10.1101\/2022.06.14.22276401v1.full#F4\">\u0395\u03b9\u03ba\u03cc\u03bd\u03b1 S2 <\/a>, <a id=\"xref-fig-5-1\" class=\"xref-fig\" href=\"https:\/\/www.medrxiv.org\/content\/10.1101\/2022.06.14.22276401v1.full#F5\">S3 <\/a>).<\/p>\n<div id=\"F4\" class=\"fig pos-float type-figure odd\">\n<div class=\"highwire-figure\">\n<div class=\"fig-inline-img-wrapper\">\n<div class=\"fig-inline-img\"><a class=\"highwire-fragment fragment-images colorbox-load highwireFiguresMarkupProcessor-processed cboxElement\" title=\"\u0395\u03c0\u03af\u03c0\u03b5\u03b4\u03b1 \u03ba\u03c5\u03c4\u03bf\u03ba\u03af\u03bd\u03b7\u03c2 \u03c3\u03b5 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 PASC \u03ba\u03b1\u03b9 COVID-19. \u039c\u03b5\u03c4\u03c1\u03ae\u03b8\u03b7\u03ba\u03b5 \u03b7 \u03c3\u03c5\u03b3\u03ba\u03ad\u03bd\u03c4\u03c1\u03c9\u03c3\u03b7 \u03bc\u03b9\u03b1\u03c2 \u03bf\u03bc\u03ac\u03b4\u03b1\u03c2 \u03ba\u03c5\u03c4\u03bf\u03ba\u03b9\u03bd\u03ce\u03bd \u03c3\u03b5 \u03b4\u03b5\u03af\u03b3\u03bc\u03b1\u03c4\u03b1 \u03c0\u03bb\u03ac\u03c3\u03bc\u03b1\u03c4\u03bf\u03c2 \u03c0\u03bf\u03c5 \u03c3\u03c5\u03bb\u03bb\u03ad\u03c7\u03b8\u03b7\u03ba\u03b1\u03bd \u03b1\u03c0\u03cc \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 PASC \u03ba\u03b1\u03b9 COVID-19. \u0395\u03ac\u03bd \u03c0\u03c1\u03b1\u03b3\u03bc\u03b1\u03c4\u03bf\u03c0\u03bf\u03b9\u03ae\u03b8\u03b7\u03ba\u03b5 \u03b4\u03b9\u03b1\u03bc\u03ae\u03ba\u03b7\u03c2 \u03b4\u03b5\u03b9\u03b3\u03bc\u03b1\u03c4\u03bf\u03bb\u03b7\u03c8\u03af\u03b1, \u03b7 \u03bc\u03ad\u03b3\u03b9\u03c3\u03c4\u03b7 \u03c4\u03b9\u03bc\u03ae \u03b1\u03c0\u03b5\u03b9\u03ba\u03bf\u03bd\u03af\u03b6\u03b5\u03c4\u03b1\u03b9. \u03a4\u03b1 \u03c3\u03b7\u03bc\u03b5\u03af\u03b1 \u03b4\u03b5\u03b4\u03bf\u03bc\u03ad\u03bd\u03c9\u03bd \u03b1\u03bd\u03c4\u03b9\u03c0\u03c1\u03bf\u03c3\u03c9\u03c0\u03b5\u03cd\u03bf\u03c5\u03bd \u03c4\u03b9\u03c2 \u03bc\u03ad\u03c3\u03b5\u03c2 \u03c4\u03b9\u03bc\u03ad\u03c2 (n = 2) \u03ba\u03b1\u03b9 \u03bf\u03b9 \u03bf\u03c1\u03b9\u03b6\u03cc\u03bd\u03c4\u03b9\u03b5\u03c2 \u03c1\u03ac\u03b2\u03b4\u03bf\u03b9 \u03c5\u03c0\u03bf\u03b4\u03b5\u03b9\u03ba\u03bd\u03cd\u03bf\u03c5\u03bd \u03c4\u03b9\u03c2 \u03b4\u03b9\u03ac\u03bc\u03b5\u03c3\u03b5\u03c2 \u03c3\u03c5\u03b3\u03ba\u03b5\u03bd\u03c4\u03c1\u03ce\u03c3\u03b5\u03b9\u03c2 \u03b3\u03b9\u03b1 \u03ba\u03ac\u03b8\u03b5 \u03ba\u03c5\u03c4\u03bf\u03ba\u03af\u03bd\u03b7.\" href=\"https:\/\/www.medrxiv.org\/content\/medrxiv\/early\/2022\/06\/16\/2022.06.14.22276401\/F4.large.jpg?width=800&amp;height=600&amp;carousel=1\" rel=\"gallery-fragment-images-1154678168\" data-figure-caption=\"&lt;div class=&quot;highwire-markup&quot;&gt;&lt;span xmlns=&quot;http:\/\/www.w3.org\/1999\/xhtml&quot; class=&quot;caption-title&quot;&gt;Cytokine levels in PASC and COVID-19 patients.&lt;\/span&gt; Measured concentration of a panel of cytokines in plasma samples collected from PASC and COVID-19 patients. If longitudinal sampling was performed, the maximal value is plotted. Data points represent mean values (n = 2) and horizontal bars indicate the median concentrations for each cytokine.&lt;\/div&gt;\" data-icon-position=\"\" data-hide-link-title=\"0\"><span class=\"hw-responsive-img\"><img loading=\"lazy\" decoding=\"async\" class=\"highwire-fragment fragment-image lazyloaded\" src=\"https:\/\/www.medrxiv.org\/content\/medrxiv\/early\/2022\/06\/16\/2022.06.14.22276401\/F4.medium.gif\" alt=\"\u0395\u03b9\u03ba\u03cc\u03bd\u03b1 S2.\" width=\"440\" height=\"226\" data-src=\"https:\/\/www.medrxiv.org\/content\/medrxiv\/early\/2022\/06\/16\/2022.06.14.22276401\/F4.medium.gif\" \/><\/span><\/a><\/div>\n<\/div>\n<ul class=\"highwire-figure-links inline\">\n<li class=\"download-fig first\"><a class=\"highwire-figure-link highwire-figure-link-download\" title=\"\u039a\u03b1\u03c4\u03b5\u03b2\u03ac\u03c3\u03c4\u03b5 \u03c4\u03bf \u03a3\u03c7\u03ae\u03bc\u03b1 S2.\" href=\"https:\/\/www.medrxiv.org\/content\/medrxiv\/early\/2022\/06\/16\/2022.06.14.22276401\/F4.large.jpg?download=true\" data-icon-position=\"\" data-hide-link-title=\"0\">\u039b\u03ae\u03c8\u03b7 \u03b5\u03b9\u03ba\u03cc\u03bd\u03b1\u03c2 <\/a><\/li>\n<li class=\"new-tab last\"><a class=\"highwire-figure-link highwire-figure-link-newtab\" href=\"https:\/\/www.medrxiv.org\/content\/medrxiv\/early\/2022\/06\/16\/2022.06.14.22276401\/F4.large.jpg\" target=\"_blank\" rel=\"noopener\" data-icon-position=\"\" data-hide-link-title=\"0\">\u0386\u03bd\u03bf\u03b9\u03b3\u03bc\u03b1 \u03c3\u03b5 \u03bd\u03ad\u03b1 \u03ba\u03b1\u03c1\u03c4\u03ad\u03bb\u03b1 <\/a><\/li>\n<\/ul>\n<\/div>\n<div class=\"fig-caption\">\n<p><span class=\"fig-label\">\u0395\u03b9\u03ba\u03cc\u03bd\u03b1 S2. <\/span> <span class=\"caption-title\">\u0395\u03c0\u03af\u03c0\u03b5\u03b4\u03b1 \u03ba\u03c5\u03c4\u03bf\u03ba\u03af\u03bd\u03b7\u03c2 \u03c3\u03b5 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 PASC \u03ba\u03b1\u03b9 COVID-19. <\/span><\/p>\n<p id=\"p-36\" class=\"first-child\">\u039c\u03b5\u03c4\u03c1\u03ae\u03b8\u03b7\u03ba\u03b5 \u03b7 \u03c3\u03c5\u03b3\u03ba\u03ad\u03bd\u03c4\u03c1\u03c9\u03c3\u03b7 \u03bc\u03b9\u03b1\u03c2 \u03bf\u03bc\u03ac\u03b4\u03b1\u03c2 \u03ba\u03c5\u03c4\u03bf\u03ba\u03b9\u03bd\u03ce\u03bd \u03c3\u03b5 \u03b4\u03b5\u03af\u03b3\u03bc\u03b1\u03c4\u03b1 \u03c0\u03bb\u03ac\u03c3\u03bc\u03b1\u03c4\u03bf\u03c2 \u03c0\u03bf\u03c5 \u03c3\u03c5\u03bb\u03bb\u03ad\u03c7\u03b8\u03b7\u03ba\u03b1\u03bd \u03b1\u03c0\u03cc \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 PASC \u03ba\u03b1\u03b9 COVID-19. \u0395\u03ac\u03bd \u03c0\u03c1\u03b1\u03b3\u03bc\u03b1\u03c4\u03bf\u03c0\u03bf\u03b9\u03ae\u03b8\u03b7\u03ba\u03b5 \u03b4\u03b9\u03b1\u03bc\u03ae\u03ba\u03b7\u03c2 \u03b4\u03b5\u03b9\u03b3\u03bc\u03b1\u03c4\u03bf\u03bb\u03b7\u03c8\u03af\u03b1, \u03b7 \u03bc\u03ad\u03b3\u03b9\u03c3\u03c4\u03b7 \u03c4\u03b9\u03bc\u03ae \u03b1\u03c0\u03b5\u03b9\u03ba\u03bf\u03bd\u03af\u03b6\u03b5\u03c4\u03b1\u03b9. \u03a4\u03b1 \u03c3\u03b7\u03bc\u03b5\u03af\u03b1 \u03b4\u03b5\u03b4\u03bf\u03bc\u03ad\u03bd\u03c9\u03bd \u03b1\u03bd\u03c4\u03b9\u03c0\u03c1\u03bf\u03c3\u03c9\u03c0\u03b5\u03cd\u03bf\u03c5\u03bd \u03c4\u03b9\u03c2 \u03bc\u03ad\u03c3\u03b5\u03c2 \u03c4\u03b9\u03bc\u03ad\u03c2 (n = 2) \u03ba\u03b1\u03b9 \u03bf\u03b9 \u03bf\u03c1\u03b9\u03b6\u03cc\u03bd\u03c4\u03b9\u03b5\u03c2 \u03c1\u03ac\u03b2\u03b4\u03bf\u03b9 \u03c5\u03c0\u03bf\u03b4\u03b5\u03b9\u03ba\u03bd\u03cd\u03bf\u03c5\u03bd \u03c4\u03b9\u03c2 \u03b4\u03b9\u03ac\u03bc\u03b5\u03c3\u03b5\u03c2 \u03c3\u03c5\u03b3\u03ba\u03b5\u03bd\u03c4\u03c1\u03ce\u03c3\u03b5\u03b9\u03c2 \u03b3\u03b9\u03b1 \u03ba\u03ac\u03b8\u03b5 \u03ba\u03c5\u03c4\u03bf\u03ba\u03af\u03bd\u03b7.<\/p>\n<div class=\"sb-div caption-clear\"><\/div>\n<\/div>\n<\/div>\n<div id=\"F5\" class=\"fig pos-float type-figure odd\">\n<div class=\"highwire-figure\">\n<div class=\"fig-inline-img-wrapper\">\n<div class=\"fig-inline-img\"><a class=\"highwire-fragment fragment-images colorbox-load highwireFiguresMarkupProcessor-processed cboxElement\" title=\"\u03a7\u03c1\u03bf\u03bd\u03b9\u03ba\u03cc \u03c0\u03c1\u03bf\u03c6\u03af\u03bb \u03ba\u03c5\u03c4\u03bf\u03ba\u03b9\u03bd\u03ce\u03bd \u03b3\u03b9\u03b1 \u03bc\u03b5\u03bc\u03bf\u03bd\u03c9\u03bc\u03ad\u03bd\u03bf\u03c5\u03c2 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 PASC. \u0397 \u03c3\u03c5\u03b3\u03ba\u03ad\u03bd\u03c4\u03c1\u03c9\u03c3\u03b7 10 \u03ba\u03c5\u03c4\u03bf\u03ba\u03b9\u03bd\u03ce\u03bd \u03bc\u03b5\u03c4\u03c1\u03ae\u03b8\u03b7\u03ba\u03b5 \u03bc\u03b5 \u03c4\u03b7\u03bd \u03c0\u03ac\u03c1\u03bf\u03b4\u03bf \u03c4\u03bf\u03c5 \u03c7\u03c1\u03cc\u03bd\u03bf\u03c5 \u03b3\u03b9\u03b1 12 \u03bc\u03b5\u03bc\u03bf\u03bd\u03c9\u03bc\u03ad\u03bd\u03bf\u03c5\u03c2 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 PASC, \u03c0\u03bf\u03c5 \u03b1\u03bd\u03c4\u03b9\u03c3\u03c4\u03bf\u03b9\u03c7\u03bf\u03cd\u03bd \u03c3\u03c4\u03bf\u03c5\u03c2 \u03af\u03b4\u03b9\u03bf\u03c5\u03c2 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03c0\u03bf\u03c5 \u03c6\u03b1\u03af\u03bd\u03bf\u03bd\u03c4\u03b1\u03b9 \u03c3\u03c4\u03bf \u03a3\u03c7\u03ae\u03bc\u03b1 2. \u039f\u03b9 \u03b3\u03ba\u03c1\u03af\u03b6\u03b5\u03c2 \u03ba\u03ac\u03b8\u03b5\u03c4\u03b5\u03c2 \u03b3\u03c1\u03b1\u03bc\u03bc\u03ad\u03c2 \u03b1\u03bd\u03c4\u03b9\u03c3\u03c4\u03bf\u03b9\u03c7\u03bf\u03cd\u03bd \u03c3\u03c4\u03bf\u03c5\u03c2 \u03c7\u03c1\u03cc\u03bd\u03bf\u03c5\u03c2 \u03c0\u03bf\u03c5 \u03ba\u03ac\u03b8\u03b5 \u03b1\u03c3\u03b8\u03b5\u03bd\u03ae\u03c2 \u03ad\u03bb\u03b1\u03b2\u03b5 \u03b5\u03af\u03c4\u03b5 \u03c4\u03b7\u03bd \u03c0\u03c1\u03ce\u03c4\u03b7, \u03c4\u03b7 \u03b4\u03b5\u03cd\u03c4\u03b5\u03c1\u03b7 \u03ae \u03c4\u03b7\u03bd \u03c4\u03c1\u03af\u03c4\u03b7 \u03b4\u03cc\u03c3\u03b7 \u03b5\u03bd\u03cc\u03c2 \u03b5\u03bc\u03b2\u03bf\u03bb\u03af\u03bf\u03c5 COVID-19. \u03a4\u03b1 \u03c3\u03b7\u03bc\u03b5\u03af\u03b1 \u03b4\u03b5\u03b4\u03bf\u03bc\u03ad\u03bd\u03c9\u03bd \u03b1\u03bd\u03c4\u03b9\u03c0\u03c1\u03bf\u03c3\u03c9\u03c0\u03b5\u03cd\u03bf\u03c5\u03bd \u03bc\u03ad\u03c3\u03b5\u03c2 \u03c4\u03b9\u03bc\u03ad\u03c2 \u00b1 SD (n = 2).\" href=\"https:\/\/www.medrxiv.org\/content\/medrxiv\/early\/2022\/06\/16\/2022.06.14.22276401\/F5.large.jpg?width=800&amp;height=600&amp;carousel=1\" rel=\"gallery-fragment-images-1154678168\" data-figure-caption=\"&lt;div class=&quot;highwire-markup&quot;&gt;&lt;span xmlns=&quot;http:\/\/www.w3.org\/1999\/xhtml&quot; class=&quot;caption-title&quot;&gt;Temporal profiling of cytokines for individual PASC patients.&lt;\/span&gt; The concentration of 10 cytokines measured over time for 12 individual PASC patients, corresponding to the same patients shown in Figure 2. Grey vertical lines correspond to the times when each patient received either the first, second or third dose of a COVID-19 vaccine. Data points represent mean values \u00b1 SD (n = 2).&lt;\/div&gt;\" data-icon-position=\"\" data-hide-link-title=\"0\"><span class=\"hw-responsive-img\"><img loading=\"lazy\" decoding=\"async\" class=\"highwire-fragment fragment-image lazyloaded\" src=\"https:\/\/www.medrxiv.org\/content\/medrxiv\/early\/2022\/06\/16\/2022.06.14.22276401\/F5.medium.gif\" alt=\"\u0395\u03b9\u03ba\u03cc\u03bd\u03b1 S3.\" width=\"651\" height=\"429\" data-src=\"https:\/\/www.medrxiv.org\/content\/medrxiv\/early\/2022\/06\/16\/2022.06.14.22276401\/F5.medium.gif\" \/><\/span><\/a><\/div>\n<\/div>\n<ul class=\"highwire-figure-links inline\">\n<li class=\"download-fig first\"><a class=\"highwire-figure-link highwire-figure-link-download\" title=\"\u039a\u03b1\u03c4\u03b5\u03b2\u03ac\u03c3\u03c4\u03b5 \u03c4\u03bf \u03a3\u03c7\u03ae\u03bc\u03b1 S3.\" href=\"https:\/\/www.medrxiv.org\/content\/medrxiv\/early\/2022\/06\/16\/2022.06.14.22276401\/F5.large.jpg?download=true\" data-icon-position=\"\" data-hide-link-title=\"0\">\u039b\u03ae\u03c8\u03b7 \u03b5\u03b9\u03ba\u03cc\u03bd\u03b1\u03c2 <\/a><\/li>\n<li class=\"new-tab last\"><a class=\"highwire-figure-link highwire-figure-link-newtab\" href=\"https:\/\/www.medrxiv.org\/content\/medrxiv\/early\/2022\/06\/16\/2022.06.14.22276401\/F5.large.jpg\" target=\"_blank\" rel=\"noopener\" data-icon-position=\"\" data-hide-link-title=\"0\">\u0386\u03bd\u03bf\u03b9\u03b3\u03bc\u03b1 \u03c3\u03b5 \u03bd\u03ad\u03b1 \u03ba\u03b1\u03c1\u03c4\u03ad\u03bb\u03b1 <\/a><\/li>\n<\/ul>\n<\/div>\n<div class=\"fig-caption\">\n<p><span class=\"fig-label\">\u0395\u03b9\u03ba\u03cc\u03bd\u03b1 S3. <\/span> <span class=\"caption-title\">\u03a7\u03c1\u03bf\u03bd\u03b9\u03ba\u03cc \u03c0\u03c1\u03bf\u03c6\u03af\u03bb \u03ba\u03c5\u03c4\u03bf\u03ba\u03b9\u03bd\u03ce\u03bd \u03b3\u03b9\u03b1 \u03bc\u03b5\u03bc\u03bf\u03bd\u03c9\u03bc\u03ad\u03bd\u03bf\u03c5\u03c2 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 PASC. <\/span><\/p>\n<p id=\"p-37\" class=\"first-child\">\u0397 \u03c3\u03c5\u03b3\u03ba\u03ad\u03bd\u03c4\u03c1\u03c9\u03c3\u03b7 10 \u03ba\u03c5\u03c4\u03bf\u03ba\u03b9\u03bd\u03ce\u03bd \u03bc\u03b5\u03c4\u03c1\u03ae\u03b8\u03b7\u03ba\u03b5 \u03bc\u03b5 \u03c4\u03b7\u03bd \u03c0\u03ac\u03c1\u03bf\u03b4\u03bf \u03c4\u03bf\u03c5 \u03c7\u03c1\u03cc\u03bd\u03bf\u03c5 \u03b3\u03b9\u03b1 12 \u03bc\u03b5\u03bc\u03bf\u03bd\u03c9\u03bc\u03ad\u03bd\u03bf\u03c5\u03c2 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 PASC, \u03c0\u03bf\u03c5 \u03b1\u03bd\u03c4\u03b9\u03c3\u03c4\u03bf\u03b9\u03c7\u03bf\u03cd\u03bd \u03c3\u03c4\u03bf\u03c5\u03c2 \u03af\u03b4\u03b9\u03bf\u03c5\u03c2 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03c0\u03bf\u03c5 \u03c6\u03b1\u03af\u03bd\u03bf\u03bd\u03c4\u03b1\u03b9 \u03c3\u03c4\u03bf <a id=\"xref-fig-2-2\" class=\"xref-fig\" href=\"https:\/\/www.medrxiv.org\/content\/10.1101\/2022.06.14.22276401v1.full#F2\">\u03a3\u03c7\u03ae\u03bc\u03b1 2 <\/a>. \u039f\u03b9 \u03b3\u03ba\u03c1\u03af\u03b6\u03b5\u03c2 \u03ba\u03ac\u03b8\u03b5\u03c4\u03b5\u03c2 \u03b3\u03c1\u03b1\u03bc\u03bc\u03ad\u03c2 \u03b1\u03bd\u03c4\u03b9\u03c3\u03c4\u03bf\u03b9\u03c7\u03bf\u03cd\u03bd \u03c3\u03c4\u03bf\u03c5\u03c2 \u03c7\u03c1\u03cc\u03bd\u03bf\u03c5\u03c2 \u03c0\u03bf\u03c5 \u03ba\u03ac\u03b8\u03b5 \u03b1\u03c3\u03b8\u03b5\u03bd\u03ae\u03c2 \u03ad\u03bb\u03b1\u03b2\u03b5 \u03b5\u03af\u03c4\u03b5 \u03c4\u03b7\u03bd \u03c0\u03c1\u03ce\u03c4\u03b7, \u03c4\u03b7 \u03b4\u03b5\u03cd\u03c4\u03b5\u03c1\u03b7 \u03ae \u03c4\u03b7\u03bd \u03c4\u03c1\u03af\u03c4\u03b7 \u03b4\u03cc\u03c3\u03b7 \u03b5\u03bc\u03b2\u03bf\u03bb\u03af\u03bf\u03c5 \u03b3\u03b9\u03b1 \u03c4\u03bf\u03bd COVID-19. \u03a4\u03b1 \u03c3\u03b7\u03bc\u03b5\u03af\u03b1 \u03b4\u03b5\u03b4\u03bf\u03bc\u03ad\u03bd\u03c9\u03bd \u03b1\u03bd\u03c4\u03b9\u03c0\u03c1\u03bf\u03c3\u03c9\u03c0\u03b5\u03cd\u03bf\u03c5\u03bd \u03bc\u03ad\u03c3\u03b5\u03c2 \u03c4\u03b9\u03bc\u03ad\u03c2 \u00b1 SD (n = 2).<\/p>\n<div class=\"sb-div caption-clear\"><\/div>\n<\/div>\n<\/div>\n<\/div>\n<div id=\"sec-3\" class=\"section\">\n<h2 class=\"\">\u03a3\u03c5\u03b6\u03ae\u03c4\u03b7\u03c3\u03b7<\/h2>\n<p id=\"p-23\">\u039c\u03b5 \u03c3\u03c4\u03cc\u03c7\u03bf \u03c4\u03b7\u03bd \u03b1\u03bd\u03b1\u03ba\u03ac\u03bb\u03c5\u03c8\u03b7 \u03b2\u03b9\u03bf\u03b4\u03b5\u03b9\u03ba\u03c4\u03ce\u03bd \u03c0\u03bf\u03c5 \u03c3\u03c5\u03c3\u03c7\u03b5\u03c4\u03af\u03b6\u03bf\u03bd\u03c4\u03b1\u03b9 \u03bc\u03b5 \u03c4\u03bf PASC, \u03bc\u03b5\u03c4\u03c1\u03ae\u03c3\u03b1\u03bc\u03b5 \u03c4\u03b7 \u03c3\u03c5\u03b3\u03ba\u03ad\u03bd\u03c4\u03c1\u03c9\u03c3\u03b7 \u03c4\u03c9\u03bd \u03b1\u03bd\u03c4\u03b9\u03b3\u03cc\u03bd\u03c9\u03bd SARS-CoV-2 \u03ba\u03b1\u03b9 \u03c4\u03c9\u03bd \u03ba\u03c5\u03c4\u03bf\u03ba\u03b9\u03bd\u03ce\u03bd \u03c3\u03b5 \u03b4\u03b5\u03af\u03b3\u03bc\u03b1\u03c4\u03b1 \u03c0\u03bb\u03ac\u03c3\u03bc\u03b1\u03c4\u03bf\u03c2 \u03c0\u03bf\u03c5 \u03c3\u03c5\u03bb\u03bb\u03ad\u03c7\u03b8\u03b7\u03ba\u03b1\u03bd \u03b1\u03c0\u03cc \u03bc\u03b9\u03b1 \u03bf\u03bc\u03ac\u03b4\u03b1 \u03b1\u03c3\u03b8\u03b5\u03bd\u03ce\u03bd \u03bc\u03b5 PASC \u03ba\u03b1\u03b9 COVID-19. \u03a4\u03bf \u03c0\u03b9\u03bf \u03b1\u03be\u03b9\u03bf\u03c3\u03b7\u03bc\u03b5\u03af\u03c9\u03c4\u03bf \u03b5\u03af\u03bd\u03b1\u03b9 \u03cc\u03c4\u03b9 \u03b5\u03bd\u03c4\u03bf\u03c0\u03af\u03c3\u03b1\u03bc\u03b5 \u03ba\u03c5\u03ba\u03bb\u03bf\u03c6\u03bf\u03c1\u03b9\u03b1\u03ba\u03ae \u03b1\u03b9\u03c7\u03bc\u03ae SARS-CoV-2 \u03c3\u03c4\u03b7\u03bd \u03c0\u03bb\u03b5\u03b9\u03bf\u03bd\u03cc\u03c4\u03b7\u03c4\u03b1 \u03c4\u03c9\u03bd \u03b1\u03c3\u03b8\u03b5\u03bd\u03ce\u03bd \u03bc\u03b5 PASC, \u03b1\u03bb\u03bb\u03ac \u03c3\u03b5 \u03ba\u03b1\u03bd\u03ad\u03bd\u03b1\u03bd \u03b1\u03c0\u03cc \u03c4\u03bf\u03c5\u03c2 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 COVID-19. \u0391\u03bd \u03ba\u03b1\u03b9 \u03c4\u03bf \u03bc\u03ad\u03b3\u03b5\u03b8\u03bf\u03c2 \u03c4\u03bf\u03c5 \u03b4\u03b5\u03af\u03b3\u03bc\u03b1\u03c4\u03cc\u03c2 \u03bc\u03b1\u03c2 \u03b5\u03af\u03bd\u03b1\u03b9 \u03bc\u03b9\u03ba\u03c1\u03cc,<strong> \u03b7 \u03b1\u03bd\u03af\u03c7\u03bd\u03b5\u03c5\u03c3\u03b7 \u03b1\u03b9\u03c7\u03bc\u03ae\u03c2 \u03c3\u03b5 \u03c0\u03bf\u03bb\u03bb\u03b1\u03c0\u03bb\u03ac \u03c7\u03c1\u03bf\u03bd\u03b9\u03ba\u03ac \u03c3\u03b7\u03bc\u03b5\u03af\u03b1 2-12 \u03bc\u03ae\u03bd\u03b5\u03c2 \u03bc\u03b5\u03c4\u03ac \u03c4\u03b7 \u03bc\u03cc\u03bb\u03c5\u03bd\u03c3\u03b7 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b5\u03c0\u03b9\u03c4\u03b1\u03ba\u03c4\u03b9\u03ba\u03ae<\/strong>. \u039f\u03b9 \u03c7\u03c1\u03bf\u03bd\u03b9\u03ba\u03ad\u03c2 \u03b4\u03b9\u03b1\u03ba\u03c5\u03bc\u03ac\u03bd\u03c3\u03b5\u03b9\u03c2 \u03c3\u03c4\u03b1 \u03b5\u03c0\u03af\u03c0\u03b5\u03b4\u03b1 \u03b1\u03bd\u03c4\u03b9\u03b3\u03cc\u03bd\u03bf\u03c5 \u03b3\u03b9\u03b1 \u03ad\u03bd\u03b1 \u03c5\u03c0\u03bf\u03c3\u03cd\u03bd\u03bf\u03bb\u03bf \u03b1\u03c4\u03cc\u03bc\u03c9\u03bd \u03c5\u03c0\u03bf\u03b4\u03b7\u03bb\u03ce\u03bd\u03bf\u03c5\u03bd \u03c4\u03b7 \u03c3\u03b7\u03bc\u03b1\u03c3\u03af\u03b1 \u03c4\u03b7\u03c2 \u03b4\u03b9\u03b1\u03bc\u03ae\u03ba\u03bf\u03c5\u03c2 \u03b4\u03b5\u03b9\u03b3\u03bc\u03b1\u03c4\u03bf\u03bb\u03b7\u03c8\u03af\u03b1\u03c2, \u03ba\u03b1\u03b8\u03ce\u03c2 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03bc\u03b7\u03bd \u03ad\u03c7\u03bf\u03c5\u03bc\u03b5 \u03b5\u03bd\u03c4\u03bf\u03c0\u03af\u03c3\u03b5\u03b9 \u03b1\u03bd\u03c4\u03b9\u03b3\u03cc\u03bd\u03bf \u03c3\u03b5 \u03bf\u03c1\u03b9\u03c3\u03bc\u03ad\u03bd\u03b5\u03c2 \u03c0\u03b5\u03c1\u03b9\u03c0\u03c4\u03ce\u03c3\u03b5\u03b9\u03c2 \u03b5\u03ac\u03bd \u03c4\u03bf \u03b1\u03af\u03bc\u03b1 \u03b5\u03af\u03c7\u03b5 \u03c3\u03c5\u03bb\u03bb\u03b5\u03c7\u03b8\u03b5\u03af \u03c3\u03b5 \u03ad\u03bd\u03b1 \u03bc\u03cc\u03bd\u03bf \u03c7\u03c1\u03bf\u03bd\u03b9\u03ba\u03cc \u03c3\u03b7\u03bc\u03b5\u03af\u03bf. \u0395\u03c0\u03b9\u03c0\u03bb\u03ad\u03bf\u03bd, \u03cc\u03c3\u03bf\u03b9 \u03c0\u03c1\u03bf\u03c3\u03c6\u03ad\u03c1\u03bf\u03bd\u03c4\u03b1\u03b9 \u03b5\u03b8\u03b5\u03bb\u03bf\u03bd\u03c4\u03b9\u03ba\u03ac \u03bd\u03b1 \u03c3\u03c5\u03bc\u03bc\u03b5\u03c4\u03ac\u03c3\u03c7\u03bf\u03c5\u03bd \u03c3\u03b5 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b5\u03c2 PASC \u03c4\u03b5\u03af\u03bd\u03bf\u03c5\u03bd \u03bd\u03b1 \u03ad\u03c7\u03bf\u03c5\u03bd \u03bd\u03bf\u03c3\u03b7\u03bb\u03b5\u03c5\u03c4\u03b5\u03af \u03bc\u03b5 \u03c3\u03bf\u03b2\u03b1\u03c1\u03cc COVID-19, \u03c0\u03b1\u03c1\u03ac \u03c4\u03bf \u03b3\u03b5\u03b3\u03bf\u03bd\u03cc\u03c2 \u03cc\u03c4\u03b9 \u03b7 \u03c0\u03bb\u03b5\u03b9\u03bf\u03c8\u03b7\u03c6\u03af\u03b1 \u03cc\u03c3\u03c9\u03bd \u03b1\u03c0\u03bf\u03ba\u03c4\u03bf\u03cd\u03bd SARS-CoV-2 \u03ba\u03b1\u03b9 \u03b1\u03bd\u03b1\u03c0\u03c4\u03cd\u03c3\u03c3\u03bf\u03c5\u03bd PASC \u03b4\u03b5\u03bd \u03bd\u03bf\u03c3\u03b7\u03bb\u03b5\u03cd\u03bf\u03bd\u03c4\u03b1\u03b9. <sup><a id=\"xref-ref-13-2\" class=\"xref-bibr\" href=\"https:\/\/www.medrxiv.org\/content\/10.1101\/2022.06.14.22276401v1.full#ref-13\">13 <\/a><\/sup>\u0397 \u03bc\u03b5\u03b9\u03bf\u03c8\u03b7\u03c6\u03af\u03b1 \u03c4\u03b7\u03c2 \u03ba\u03bf\u03cc\u03c1\u03c4\u03b7\u03c2 \u03bc\u03b1\u03c2 PASC \u03bd\u03bf\u03c3\u03b7\u03bb\u03b5\u03cd\u03c4\u03b7\u03ba\u03b5 (n=2), \u03c5\u03c0\u03bf\u03b4\u03b7\u03bb\u03ce\u03bd\u03bf\u03bd\u03c4\u03b1\u03c2 \u03cc\u03c4\u03b9 \u03c4\u03b1 \u03b5\u03c5\u03c1\u03ae\u03bc\u03b1\u03c4\u03ac \u03bc\u03b1\u03c2 \u03c3\u03c7\u03b5\u03c4\u03af\u03b6\u03bf\u03bd\u03c4\u03b1\u03b9 \u03bc\u03b5 \u03bb\u03bf\u03af\u03bc\u03c9\u03be\u03b7 SARS-CoV-2 \u03ba\u03b1\u03b9 \u03cc\u03c7\u03b9 \u03bc\u03b5 \u03b5\u03c0\u03b9\u03c0\u03c4\u03ce\u03c3\u03b5\u03b9\u03c2 \u03c0\u03bf\u03c5 \u03c0\u03c1\u03bf\u03ba\u03cd\u03c0\u03c4\u03bf\u03c5\u03bd \u03bc\u03b5\u03c4\u03ac \u03b1\u03c0\u03cc \u03c3\u03bf\u03b2\u03b1\u03c1\u03ae \u03b1\u03c3\u03b8\u03ad\u03bd\u03b5\u03b9\u03b1 \u03ba\u03b1\u03b9 \u03bd\u03bf\u03c3\u03b7\u03bb\u03b5\u03af\u03b1.<\/p>\n<p id=\"p-24\">\u0397 \u03c0\u03b1\u03c1\u03bf\u03c5\u03c3\u03af\u03b1 \u03ba\u03c5\u03ba\u03bb\u03bf\u03c6\u03bf\u03c1\u03bf\u03cd\u03c3\u03b1\u03c2 \u03b1\u03ba\u03af\u03b4\u03b1\u03c2 \u03c5\u03c0\u03bf\u03c3\u03c4\u03b7\u03c1\u03af\u03b6\u03b5\u03b9 \u03c4\u03b7\u03bd \u03c5\u03c0\u03cc\u03b8\u03b5\u03c3\u03b7 \u03cc\u03c4\u03b9 \u03bc\u03b9\u03b1 \u03b4\u03b5\u03be\u03b1\u03bc\u03b5\u03bd\u03ae \u03b5\u03bd\u03b5\u03c1\u03b3\u03bf\u03cd \u03b9\u03bf\u03cd \u03c0\u03b1\u03c1\u03b1\u03bc\u03ad\u03bd\u03b5\u03b9 \u03c3\u03c4\u03bf \u03c3\u03ce\u03bc\u03b1. \u039c\u03b9\u03b1 \u03ac\u03bb\u03bb\u03b7 \u03c0\u03c1\u03bf\u03ba\u03b1\u03c4\u03b1\u03c1\u03ba\u03c4\u03b9\u03ba\u03ae \u03bc\u03b5\u03bb\u03ad\u03c4\u03b7 \u03b2\u03c1\u03ae\u03ba\u03b5 \u03c4\u03bf RNA \u03c4\u03bf\u03c5 SARS-CoV-2 \u03c3\u03b5 \u03c0\u03bf\u03bb\u03bb\u03b1\u03c0\u03bb\u03ad\u03c2 \u03b1\u03bd\u03b1\u03c4\u03bf\u03bc\u03b9\u03ba\u03ad\u03c2 \u03b8\u03ad\u03c3\u03b5\u03b9\u03c2 \u03ad\u03c9\u03c2 \u03ba\u03b1\u03b9 \u03b5\u03c0\u03c4\u03ac \u03bc\u03ae\u03bd\u03b5\u03c2 \u03bc\u03b5\u03c4\u03ac \u03c4\u03b7\u03bd \u03ad\u03bd\u03b1\u03c1\u03be\u03b7 \u03c4\u03c9\u03bd \u03c3\u03c5\u03bc\u03c0\u03c4\u03c9\u03bc\u03ac\u03c4\u03c9\u03bd, \u03b5\u03c0\u03b9\u03b2\u03b5\u03b2\u03b1\u03b9\u03ce\u03bd\u03bf\u03bd\u03c4\u03b1\u03c2 \u03c4\u03b7\u03bd \u03b5\u03bc\u03bc\u03bf\u03bd\u03ae \u03c4\u03bf\u03c5 \u03b9\u03b9\u03ba\u03bf\u03cd \u03b1\u03bd\u03c4\u03b9\u03b3\u03cc\u03bd\u03bf\u03c5.<strong> \u0397 \u03bc\u03b5\u03c4\u03b1\u03b8\u03b1\u03bd\u03ac\u03c4\u03b9\u03b1 \u03b1\u03bd\u03ac\u03bb\u03c5\u03c3\u03b7 \u03b9\u03c3\u03c4\u03bf\u03cd \u03b1\u03c0\u03bf\u03ba\u03ac\u03bb\u03c5\u03c8\u03b5 \u03c4\u03b7\u03bd \u03c0\u03b1\u03c1\u03bf\u03c5\u03c3\u03af\u03b1 RNA SARS-CoV-2 \u03ba\u03b1\u03b9 \u03ad\u03ba\u03c6\u03c1\u03b1\u03c3\u03b7\u03c2 \u03b5\u03b9\u03b4\u03b9\u03ba\u03ae\u03c2 \u03c0\u03c1\u03c9\u03c4\u03b5\u0390\u03bd\u03b7\u03c2 \u03b9\u03bf\u03cd \u03cc\u03c7\u03b9 \u03bc\u03cc\u03bd\u03bf \u03c3\u03b5 \u03b1\u03bd\u03b1\u03c0\u03bd\u03b5\u03c5\u03c3\u03c4\u03b9\u03ba\u03bf\u03cd\u03c2 \u03b9\u03c3\u03c4\u03bf\u03cd\u03c2, \u03b1\u03bb\u03bb\u03ac \u03ba\u03b1\u03b9 \u03c3\u03b5 \u03ba\u03b1\u03c1\u03b4\u03b9\u03b1\u03b3\u03b3\u03b5\u03b9\u03b1\u03ba\u03bf\u03cd\u03c2, \u03bb\u03b5\u03bc\u03c6\u03b9\u03ba\u03bf\u03cd\u03c2, \u03b3\u03b1\u03c3\u03c4\u03c1\u03b5\u03bd\u03c4\u03b5\u03c1\u03b9\u03ba\u03bf\u03cd\u03c2, \u03c0\u03b5\u03c1\u03b9\u03c6\u03b5\u03c1\u03b9\u03ba\u03bf\u03cd\u03c2 \u03bd\u03b5\u03c5\u03c1\u03b9\u03ba\u03bf\u03cd\u03c2 \u03ba\u03b1\u03b9 \u03b5\u03b3\u03ba\u03b5\u03c6\u03b1\u03bb\u03b9\u03ba\u03bf\u03cd\u03c2 \u03b9\u03c3\u03c4\u03bf\u03cd\u03c2 \u03c3\u03c4\u03b7\u03bd \u03c0\u03bb\u03b5\u03b9\u03bf\u03bd\u03cc\u03c4\u03b7\u03c4\u03b1 \u03c4\u03c9\u03bd \u03b1\u03c4\u03cc\u03bc\u03c9\u03bd \u03c0\u03bf\u03c5 \u03b1\u03bd\u03b1\u03bb\u03cd\u03b8\u03b7\u03ba\u03b1\u03bd (n = 44)<\/strong>. <sup><a id=\"xref-ref-21-1\" class=\"xref-bibr\" href=\"https:\/\/www.medrxiv.org\/content\/10.1101\/2022.06.14.22276401v1.full#ref-21\">21 <\/a><\/sup>\u0395\u03c0\u03b9\u03c0\u03bb\u03ad\u03bf\u03bd, \u03c3\u03c4\u03b7\u03bd \u03c0\u03c1\u03bf\u03b7\u03b3\u03bf\u03cd\u03bc\u03b5\u03bd\u03b7 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b7 \u03bc\u03b1\u03c2, \u03b2\u03c1\u03ad\u03b8\u03b7\u03ba\u03b5 \u03bd\u03b1 \u03b5\u03bc\u03c6\u03b1\u03bd\u03af\u03b6\u03b5\u03c4\u03b1\u03b9 \u03bc\u03b9\u03b1 \u03b4\u03b5\u03be\u03b1\u03bc\u03b5\u03bd\u03ae \u03b1\u03bd\u03b1\u03b4\u03b9\u03c0\u03bb\u03b1\u03c3\u03b9\u03b1\u03c3\u03bc\u03bf\u03cd \u03c4\u03bf\u03c5 SARS-CoV-2 \u03c3\u03c4\u03b7 \u03b3\u03b1\u03c3\u03c4\u03c1\u03b5\u03bd\u03c4\u03b5\u03c1\u03b9\u03ba\u03ae \u03bf\u03b4\u03cc \u03c0\u03b1\u03b9\u03b4\u03b9\u03ce\u03bd \u03c0\u03bf\u03c5 \u03b1\u03bd\u03b1\u03c0\u03c4\u03cd\u03c3\u03c3\u03bf\u03c5\u03bd <strong>\u03c0\u03bf\u03bb\u03c5\u03c3\u03c5\u03c3\u03c4\u03b7\u03bc\u03b9\u03ba\u03cc \u03c6\u03bb\u03b5\u03b3\u03bc\u03bf\u03bd\u03ce\u03b4\u03b5\u03c2 \u03c3\u03cd\u03bd\u03b4\u03c1\u03bf\u03bc\u03bf (MIS-C).<\/strong> \u03a3\u03b5 \u03b1\u03c5\u03c4\u03ae \u03c4\u03b7 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b7, \u03b5\u03bd\u03c4\u03bf\u03c0\u03af\u03c3\u03b1\u03bc\u03b5 \u03b1\u03c5\u03be\u03b7\u03bc\u03ad\u03bd\u03b1 \u03b5\u03c0\u03af\u03c0\u03b5\u03b4\u03b1 \u03ba\u03c5\u03ba\u03bb\u03bf\u03c6\u03bf\u03c1\u03b9\u03ba\u03ae\u03c2 \u03b1\u03b9\u03c7\u03bc\u03ae\u03c2 \u03b5\u03b2\u03b4\u03bf\u03bc\u03ac\u03b4\u03b5\u03c2 \u03bc\u03b5\u03c4\u03ac \u03c4\u03b7\u03bd \u03b1\u03c1\u03c7\u03b9\u03ba\u03ae \u03bc\u03cc\u03bb\u03c5\u03bd\u03c3\u03b7 SARS-CoV-2, \u03bb\u03cc\u03b3\u03c9 \u03b4\u03b9\u03b1\u03c1\u03c1\u03bf\u03ae\u03c2 \u03b1\u03c0\u03cc \u03c4\u03bf \u03ad\u03bd\u03c4\u03b5\u03c1\u03bf \u03c3\u03c4\u03b7\u03bd \u03ba\u03c5\u03ba\u03bb\u03bf\u03c6\u03bf\u03c1\u03af\u03b1 \u03c4\u03bf\u03c5 \u03b1\u03af\u03bc\u03b1\u03c4\u03bf\u03c2. <sup><a id=\"xref-ref-22-1\" class=\"xref-bibr\" href=\"https:\/\/www.medrxiv.org\/content\/10.1101\/2022.06.14.22276401v1.full#ref-22\">22 <\/a><\/sup>\u03a3\u03b5 \u03bc\u03b9\u03b1 \u03ac\u03bb\u03bb\u03b7 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b7, \u03b7 \u03b1\u03bd\u03ac\u03bb\u03c5\u03c3\u03b7 \u03c4\u03bf\u03c5 \u03bc\u03b9\u03ba\u03c1\u03bf\u03b2\u03b9\u03ce\u03bc\u03b1\u03c4\u03bf\u03c2 \u03c4\u03bf\u03c5 \u03b5\u03bd\u03c4\u03ad\u03c1\u03bf\u03c5 \u03ad\u03c9\u03c2 \u03ba\u03b1\u03b9 \u03ad\u03be\u03b9 \u03bc\u03ae\u03bd\u03b5\u03c2 \u03bc\u03b5\u03c4\u03ac \u03c4\u03b7 \u03bc\u03cc\u03bb\u03c5\u03bd\u03c3\u03b7 \u03b1\u03c0\u03cc SARS-CoV-2 \u03b1\u03c0\u03bf\u03ba\u03ac\u03bb\u03c5\u03c8\u03b5 \u03b1\u03bb\u03bb\u03b1\u03b3\u03ad\u03c2 \u03c3\u03c4\u03b7 \u03c3\u03cd\u03bd\u03b8\u03b5\u03c3\u03b7 \u03c4\u03bf\u03c5 \u03bc\u03b9\u03ba\u03c1\u03bf\u03b2\u03b9\u03ce\u03bc\u03b1\u03c4\u03bf\u03c2 \u03c4\u03bf\u03c5 \u03b5\u03bd\u03c4\u03ad\u03c1\u03bf\u03c5 \u03c0\u03bf\u03c5 \u03c3\u03c5\u03c3\u03c7\u03b5\u03c4\u03af\u03c3\u03c4\u03b7\u03ba\u03b1\u03bd \u03bc\u03b5 \u03c4\u03bf PASC, <sup><a id=\"xref-ref-23-1\" class=\"xref-bibr\" href=\"https:\/\/www.medrxiv.org\/content\/10.1101\/2022.06.14.22276401v1.full#ref-23\">23 <\/a><\/sup>\u03c5\u03c0\u03bf\u03b4\u03b7\u03bb\u03ce\u03bd\u03bf\u03bd\u03c4\u03b1\u03c2 \u03cc\u03c4\u03b9 \u03bf\u03c1\u03b9\u03c3\u03bc\u03ad\u03bd\u03b5\u03c2 \u03c3\u03c5\u03bd\u03b8\u03ae\u03ba\u03b5\u03c2 \u03ae \u03c0\u03c1\u03bf\u03b4\u03b9\u03b1\u03b8\u03ad\u03c3\u03b5\u03b9\u03c2 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b5\u03bd\u03b9\u03c3\u03c7\u03cd\u03c3\u03bf\u03c5\u03bd \u03c4\u03b7\u03bd \u03b5\u03c0\u03b9\u03bc\u03bf\u03bd\u03ae \u03c4\u03b7\u03c2 \u03b1\u03bd\u03b1\u03c0\u03b1\u03c1\u03b1\u03b3\u03c9\u03b3\u03ae\u03c2 \u03b9\u03b9\u03ba\u03ce\u03bd \u03b4\u03b5\u03be\u03b1\u03bc\u03b5\u03bd\u03ce\u03bd.<\/p>\n<p id=\"p-25\">\u0395\u03ac\u03bd \u03bf\u03b9 \u03b9\u03b9\u03ba\u03ad\u03c2 \u03b4\u03b5\u03be\u03b1\u03bc\u03b5\u03bd\u03ad\u03c2 \u03b5\u03c0\u03b9\u03bc\u03ad\u03bd\u03bf\u03c5\u03bd \u03c3\u03c4\u03bf \u03c3\u03ce\u03bc\u03b1 \u03c4\u03c9\u03bd \u03b1\u03c3\u03b8\u03b5\u03bd\u03ce\u03bd \u03bc\u03b5 PASC, \u03c4\u03cc\u03c4\u03b5 \u03b3\u03b9\u03b1\u03c4\u03af \u03b4\u03b5\u03bd \u03b1\u03bd\u03b9\u03c7\u03bd\u03b5\u03cd\u03bf\u03c5\u03bc\u03b5 \u03b5\u03c0\u03af\u03c3\u03b7\u03c2 \u03ba\u03c5\u03ba\u03bb\u03bf\u03c6\u03bf\u03c1\u03bf\u03cd\u03bd N \u03c3\u03b5 \u03bc\u03b5\u03b3\u03b1\u03bb\u03cd\u03c4\u03b5\u03c1\u03bf \u03c0\u03bf\u03c3\u03bf\u03c3\u03c4\u03cc \u03b1\u03c3\u03b8\u03b5\u03bd\u03ce\u03bd; \u0395\u03af\u03bd\u03b1\u03b9 \u03c0\u03b9\u03b8\u03b1\u03bd\u03cc \u03c4\u03bf \u039d \u03bd\u03b1 \u03c5\u03b4\u03c1\u03bf\u03bb\u03cd\u03b5\u03c4\u03b1\u03b9 \u03ba\u03b1\u03c4\u03ac \u03c0\u03c1\u03bf\u03c4\u03af\u03bc\u03b7\u03c3\u03b7, \u03b5\u03bd\u03ce \u03b7 \u03b1\u03ba\u03af\u03b4\u03b1 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03bc\u03b5\u03c4\u03b1\u03c6\u03b5\u03c1\u03b8\u03b5\u03af \u03c0\u03b9\u03bf \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03b5\u03c3\u03bc\u03b1\u03c4\u03b9\u03ba\u03ac \u03c3\u03c4\u03b7\u03bd \u03ba\u03c5\u03ba\u03bb\u03bf\u03c6\u03bf\u03c1\u03af\u03b1 \u03c4\u03bf\u03c5 \u03b1\u03af\u03bc\u03b1\u03c4\u03bf\u03c2, \u03b1\u03c0\u03bf\u03c6\u03b5\u03cd\u03b3\u03bf\u03bd\u03c4\u03b1\u03c2 \u03c4\u03b7\u03bd \u03b1\u03c0\u03bf\u03b9\u03ba\u03bf\u03b4\u03cc\u03bc\u03b7\u03c3\u03b7. \u0395\u03bd\u03b1\u03bb\u03bb\u03b1\u03ba\u03c4\u03b9\u03ba\u03ac, \u03c4\u03b1 \u03ba\u03c5\u03ba\u03bb\u03bf\u03c6\u03bf\u03c1\u03bf\u03cd\u03bd\u03c4\u03b1 \u03b1\u03bd\u03c4\u03b9\u03c3\u03ce\u03bc\u03b1\u03c4\u03b1 \u03b1\u03bd\u03c4\u03b9-\u039d \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c0\u03b9\u03bf \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03b5\u03c3\u03bc\u03b1\u03c4\u03b9\u03ba\u03ac \u03c3\u03c4\u03b7\u03bd \u03ba\u03ac\u03b8\u03b1\u03c1\u03c3\u03b7 \u03c4\u03bf\u03c5 \u039d \u03c3\u03b5 \u03c3\u03cd\u03b3\u03ba\u03c1\u03b9\u03c3\u03b7 \u03bc\u03b5 \u03c4\u03b1 \u03b1\u03bd\u03c4\u03b9\u03c3\u03ce\u03bc\u03b1\u03c4\u03b1 \u03ba\u03b1\u03c4\u03ac \u03c4\u03b7\u03c2 \u03b1\u03ba\u03af\u03b4\u03b1\u03c2 \u03c0\u03bf\u03c5 \u03c0\u03b1\u03c1\u03ac\u03b3\u03bf\u03bd\u03c4\u03b1\u03b9. <strong>\u0395\u03c0\u03b9\u03c0\u03bb\u03ad\u03bf\u03bd, \u03c4\u03bf PASC \u03b5\u03af\u03bd\u03b1\u03b9 \u03ad\u03bd\u03b1 \u03b5\u03c4\u03b5\u03c1\u03bf\u03b3\u03b5\u03bd\u03ad\u03c2 \u03c3\u03cd\u03bd\u03b4\u03c1\u03bf\u03bc\u03bf, \u03c0\u03bf\u03c5 \u03c0\u03b9\u03b8\u03b1\u03bd\u03ce\u03c2 \u03b5\u03be\u03b1\u03c1\u03c4\u03ac\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03bf\u03bd \u03b9\u03c3\u03c4\u03cc \u03c3\u03c4\u03bf\u03bd \u03bf\u03c0\u03bf\u03af\u03bf \u03b5\u03c0\u03b9\u03bc\u03ad\u03bd\u03b5\u03b9 \u03b7 \u03b9\u03b9\u03ba\u03ae \u03b4\u03b5\u03be\u03b1\u03bc\u03b5\u03bd\u03ae.<\/strong> \u0391\u03c5\u03c4\u03ae \u03b7 \u03b5\u03c4\u03b5\u03c1\u03bf\u03b3\u03ad\u03bd\u03b5\u03b9\u03b1 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03ad\u03c7\u03b5\u03b9 \u03b5\u03c0\u03af\u03b4\u03c1\u03b1\u03c3\u03b7 \u03c3\u03c4\u03bf \u03b5\u03ac\u03bd \u03c3\u03c4\u03b7 \u03c3\u03c5\u03bd\u03ad\u03c7\u03b5\u03b9\u03b1 \u03b1\u03bd\u03b9\u03c7\u03bd\u03b5\u03cd\u03b5\u03c4\u03b1\u03b9 \u03b1\u03ba\u03af\u03b4\u03b1 \u03ae \u039d. \u03b1\u03c0\u03b1\u03b9\u03c4\u03bf\u03cd\u03bd\u03c4\u03b1\u03b9 \u03bc\u03b5\u03bb\u03bb\u03bf\u03bd\u03c4\u03b9\u03ba\u03ad\u03c2 \u03ad\u03c1\u03b5\u03c5\u03bd\u03b5\u03c2 \u03b3\u03b9\u03b1 \u03c4\u03b7\u03bd \u03b5\u03c0\u03af\u03bb\u03c5\u03c3\u03b7 \u03b1\u03c5\u03c4\u03ce\u03bd \u03c4\u03c9\u03bd \u03b1\u03bd\u03b1\u03c0\u03ac\u03bd\u03c4\u03b7\u03c4\u03c9\u03bd \u03b5\u03c1\u03c9\u03c4\u03b7\u03bc\u03ac\u03c4\u03c9\u03bd.<\/p>\n<p id=\"p-26\">\u039f\u03b9 \u03b5\u03c0\u03af\u03bc\u03bf\u03bd\u03b5\u03c2 \u03b9\u03b9\u03ba\u03ad\u03c2 \u03b4\u03b5\u03be\u03b1\u03bc\u03b5\u03bd\u03ad\u03c2 \u03b5\u03af\u03bd\u03b1\u03b9 \u03bc\u03b9\u03b1 \u03c0\u03b9\u03b8\u03b1\u03bd\u03ae \u03b1\u03b9\u03c4\u03af\u03b1 \u03c3\u03c5\u03bc\u03c0\u03c4\u03c9\u03bc\u03ac\u03c4\u03c9\u03bd PASC, \u03b1\u03bb\u03bb\u03ac \u03b7 \u03ba\u03c5\u03ba\u03bb\u03bf\u03c6\u03bf\u03c1\u03b9\u03b1\u03ba\u03ae \u03b1\u03ba\u03af\u03b4\u03b1 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03b5\u03c0\u03af\u03c3\u03b7\u03c2 \u03bd\u03b1 \u03c0\u03c1\u03bf\u03ba\u03b1\u03bb\u03ad\u03c3\u03b5\u03b9 \u03c3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03b1. \u03a0\u03b1\u03c1\u03cc\u03bc\u03bf\u03b9\u03b1 \u03bc\u03b5 \u03c4\u03b1 \u03b2\u03b1\u03ba\u03c4\u03b7\u03c1\u03b9\u03b1\u03ba\u03ac \u03c5\u03c0\u03b5\u03c1\u03b1\u03bd\u03c4\u03b9\u03b3\u03cc\u03bd\u03b1, \u03b7 \u03c0\u03c1\u03c9\u03c4\u03b5\u0390\u03bd\u03b7 \u03b1\u03ba\u03af\u03b4\u03b1\u03c2 SARS-CoV-2 \u03c0\u03b5\u03c1\u03b9\u03ad\u03c7\u03b5\u03b9 \u03b4\u03bf\u03bc\u03b9\u03ba\u03ac \u03bc\u03bf\u03c4\u03af\u03b2\u03b1 \u03c0\u03bf\u03c5 \u03b1\u03bb\u03bb\u03b7\u03bb\u03b5\u03c0\u03b9\u03b4\u03c1\u03bf\u03cd\u03bd \u03ad\u03bd\u03c4\u03bf\u03bd\u03b1 \u03bc\u03b5 \u03c4\u03bf\u03c5\u03c2 \u03c5\u03c0\u03bf\u03b4\u03bf\u03c7\u03b5\u03af\u03c2 \u03c4\u03c9\u03bd \u03a4 \u03ba\u03c5\u03c4\u03c4\u03ac\u03c1\u03c9\u03bd, \u03b4\u03b7\u03bc\u03b9\u03bf\u03c5\u03c1\u03b3\u03ce\u03bd\u03c4\u03b1\u03c2 \u03bc\u03b9\u03b1 \u03b1\u03bd\u03b9\u03c3\u03bf\u03c1\u03c1\u03bf\u03c0\u03af\u03b1 \u03c3\u03c4\u03bf \u03c1\u03b5\u03c0\u03b5\u03c1\u03c4\u03cc\u03c1\u03b9\u03bf \u03c4\u03c9\u03bd \u03c5\u03c0\u03bf\u03b4\u03bf\u03c7\u03ad\u03c9\u03bd \u03a4 \u03ba\u03c5\u03c4\u03c4\u03ac\u03c1\u03c9\u03bd. <sup><a id=\"xref-ref-24-1\" class=\"xref-bibr\" href=\"https:\/\/www.medrxiv.org\/content\/10.1101\/2022.06.14.22276401v1.full#ref-24\">24 <\/a>, <a id=\"xref-ref-25-1\" class=\"xref-bibr\" href=\"https:\/\/www.medrxiv.org\/content\/10.1101\/2022.06.14.22276401v1.full#ref-25\">25 <\/a><\/sup>\u039c\u03bf\u03bd\u03b1\u03b4\u03b9\u03ba\u03cc \u03c3\u03c4\u03bf\u03bd SARS-CoV-2, \u03c0\u03b9\u03c3\u03c4\u03b5\u03cd\u03b5\u03c4\u03b1\u03b9 \u03cc\u03c4\u03b9 \u03c4\u03bf \u03bc\u03bf\u03c4\u03af\u03b2\u03bf \u03c0\u03bf\u03c5 \u03bc\u03bf\u03b9\u03ac\u03b6\u03b5\u03b9 \u03bc\u03b5 \u03c5\u03c0\u03b5\u03c1\u03b1\u03bd\u03c4\u03b9\u03b3\u03cc\u03bd\u03bf \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b5\u03c5\u03b8\u03cd\u03bd\u03b5\u03c4\u03b1\u03b9 \u03b3\u03b9\u03b1 \u03c4\u03b7\u03bd \u03c5\u03c0\u03b5\u03c1\u03c6\u03bb\u03b5\u03b3\u03bc\u03bf\u03bd\u03ce\u03b4\u03b7 \u03b1\u03c0\u03cc\u03ba\u03c1\u03b9\u03c3\u03b7 \u03c0\u03bf\u03c5 \u03c0\u03b1\u03c1\u03b1\u03c4\u03b7\u03c1\u03b5\u03af\u03c4\u03b1\u03b9 \u03c3\u03b5 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 \u03c3\u03bf\u03b2\u03b1\u03c1\u03ae COVID-19 \u03ba\u03b1\u03b9 MIS-C. \u0391\u03bd \u03ba\u03b1\u03b9 \u03b7 \u03b1\u03ba\u03af\u03b4\u03b1 \u03b4\u03b5\u03bd \u03c0\u03c1\u03bf\u03ba\u03b1\u03bb\u03b5\u03af \u03ba\u03b1\u03c4\u03b1\u03b9\u03b3\u03af\u03b4\u03b1 \u03ba\u03c5\u03c4\u03bf\u03ba\u03b9\u03bd\u03ce\u03bd \u03c3\u03b5 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 PASC, \u03b8\u03b1 \u03bc\u03c0\u03bf\u03c1\u03bf\u03cd\u03c3\u03b5 \u03bd\u03b1 \u03b4\u03c1\u03ac\u03c3\u03b5\u03b9 \u03bc\u03ad\u03c3\u03c9 \u03ac\u03bb\u03bb\u03c9\u03bd \u03bc\u03b7\u03c7\u03b1\u03bd\u03b9\u03c3\u03bc\u03ce\u03bd \u03c0\u03bf\u03c5 \u03c0\u03b1\u03c1\u03b5\u03bc\u03b2\u03b1\u03af\u03bd\u03bf\u03c5\u03bd \u03c3\u03c4\u03b7 \u03c6\u03c5\u03c3\u03b9\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ae \u03ba\u03c5\u03c4\u03c4\u03b1\u03c1\u03b9\u03ba\u03ae \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03af\u03b1. <strong>\u0393\u03b9\u03b1 \u03c0\u03b1\u03c1\u03ac\u03b4\u03b5\u03b9\u03b3\u03bc\u03b1, \u03b7 \u03b1\u03ba\u03af\u03b4\u03b1 \u03b1\u03c0\u03cc \u03bc\u03cc\u03bd\u03b7 \u03c4\u03b7\u03c2 \u03b1\u03c0\u03bf\u03b4\u03b5\u03af\u03c7\u03b8\u03b7\u03ba\u03b5 \u03cc\u03c4\u03b9 \u03b4\u03b9\u03b1\u03c4\u03b1\u03c1\u03ac\u03c3\u03c3\u03b5\u03b9 \u03c4\u03b9\u03c2 \u03bf\u03b4\u03bf\u03cd\u03c2 \u03c3\u03b7\u03bc\u03b1\u03c4\u03bf\u03b4\u03cc\u03c4\u03b7\u03c3\u03b7\u03c2 \u03ba\u03b1\u03b9 \u03c0\u03c1\u03bf\u03ba\u03b1\u03bb\u03b5\u03af \u03b4\u03c5\u03c3\u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03af\u03b1 \u03c3\u03c4\u03b1 \u03c0\u03b5\u03c1\u03b9\u03ba\u03cd\u03c4\u03c4\u03b1\u03c1\u03b1, \u03c3\u03c4\u03b1 \u03b1\u03b3\u03b3\u03b5\u03b9\u03b1\u03ba\u03ac \u03b5\u03bd\u03b4\u03bf\u03b8\u03b7\u03bb\u03b9\u03b1\u03ba\u03ac \u03ba\u03cd\u03c4\u03c4\u03b1\u03c1\u03b1 \u03ba\u03b1\u03b9 \u03c3\u03c4\u03bf\u03bd \u03b1\u03b9\u03bc\u03b1\u03c4\u03bf\u03b5\u03b3\u03ba\u03b5\u03c6\u03b1\u03bb\u03b9\u03ba\u03cc \u03c6\u03c1\u03b1\u03b3\u03bc\u03cc<\/strong>. <sup><a id=\"xref-ref-26-1\" class=\"xref-bibr\" href=\"https:\/\/www.medrxiv.org\/content\/10.1101\/2022.06.14.22276401v1.full#ref-26\">26 <\/a>\u2212 <a id=\"xref-ref-29-1\" class=\"xref-bibr\" href=\"https:\/\/www.medrxiv.org\/content\/10.1101\/2022.06.14.22276401v1.full#ref-29\">29 <\/a><\/sup>\u0395\u03bd\u03b1\u03bb\u03bb\u03b1\u03ba\u03c4\u03b9\u03ba\u03ac, \u03c4\u03bf PASC \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b5\u03ba\u03b4\u03b7\u03bb\u03c9\u03b8\u03b5\u03af \u03c9\u03c2 <strong>\u03ba\u03c5\u03c4\u03c4\u03b1\u03c1\u03b9\u03ba\u03ae \u03b5\u03be\u03ac\u03bd\u03c4\u03bb\u03b7\u03c3\u03b7 \u03ae \u03c0\u03c1\u03cc\u03ba\u03bb\u03b7\u03c3\u03b7 \u03b1\u03bd\u03b8\u03b5\u03ba\u03c4\u03b9\u03ba\u03ae\u03c2 \u03c6\u03bb\u03b5\u03b3\u03bc\u03bf\u03bd\u03ce\u03b4\u03bf\u03c5\u03c2 \u03b1\u03c0\u03cc\u03ba\u03c1\u03b9\u03c3\u03b7\u03c2 \u2212 \u03b1\u03bb\u03bb\u03ac \u03bc\u03b5 \u03b5\u03c0\u03af\u03bc\u03bf\u03bd\u03b7 \u03b5\u03bd\u03c4\u03bf\u03c0\u03b9\u03c3\u03bc\u03ad\u03bd\u03b7 \u03b9\u03c3\u03c4\u03b9\u03ba\u03ae \u03b4\u03c5\u03c3\u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03af\u03b1.<\/strong><\/p>\n<p id=\"p-27\">\u0395\u03ac\u03bd \u03c4\u03bf PASC \u03b5\u03af\u03bd\u03b1\u03b9 \u03b1\u03c0\u03bf\u03c4\u03ad\u03bb\u03b5\u03c3\u03bc\u03b1 \u03b5\u03c0\u03af\u03bc\u03bf\u03bd\u03b7\u03c2 \u03b9\u03b9\u03ba\u03ae\u03c2 \u03b1\u03bd\u03b1\u03c0\u03b1\u03c1\u03b1\u03b3\u03c9\u03b3\u03ae\u03c2 \u03c3\u03b5 \u03b9\u03c3\u03c4\u03bf\u03cd\u03c2 \u03b5\u03ba\u03c4\u03cc\u03c2 \u03c4\u03bf\u03c5 \u03c0\u03bd\u03b5\u03cd\u03bc\u03bf\u03bd\u03b1, \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03b5\u03c0\u03af\u03c3\u03b7\u03c2 \u03bd\u03b1 \u03b5\u03be\u03b7\u03b3\u03ae\u03c3\u03b5\u03b9 \u03b3\u03b9\u03b1\u03c4\u03af \u03bf\u03b9 \u03b1\u03bb\u03bb\u03b1\u03b3\u03ad\u03c2 \u03c3\u03c4\u03bf\u03c5\u03c2 \u03ba\u03c5\u03ba\u03bb\u03bf\u03c6\u03bf\u03c1\u03bf\u03cd\u03bd\u03c4\u03b5\u03c2 \u03c6\u03bb\u03b5\u03b3\u03bc\u03bf\u03bd\u03ce\u03b4\u03b5\u03b9\u03c2 \u03b4\u03b5\u03af\u03ba\u03c4\u03b5\u03c2 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b1\u03bd\u03b5\u03c0\u03b1\u03af\u03c3\u03b8\u03b7\u03c4\u03b5\u03c2 \u03cc\u03c4\u03b1\u03bd \u03bc\u03b5\u03c4\u03c1\u03ce\u03bd\u03c4\u03b1\u03b9 \u03c3\u03c4\u03bf \u03b1\u03af\u03bc\u03b1, \u03b1\u03bd \u03ba\u03b1\u03b9 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b1\u03c5\u03be\u03b7\u03bc\u03ad\u03bd\u03b5\u03c2 \u03c3\u03b5 \u03ad\u03bd\u03b1\u03bd \u03b4\u03b5\u03b4\u03bf\u03bc\u03ad\u03bd\u03bf \u03b9\u03c3\u03c4\u03cc. \u0386\u03bb\u03bb\u03b5\u03c2 \u03b5\u03c1\u03b3\u03b1\u03c3\u03af\u03b5\u03c2 \u03c5\u03c0\u03bf\u03b4\u03b5\u03b9\u03ba\u03bd\u03cd\u03bf\u03c5\u03bd \u03bc\u03b9\u03b1 \u03c4\u03ac\u03c3\u03b7 \u03c0\u03c1\u03bf\u03c2 \u03b1\u03c5\u03be\u03b7\u03bc\u03ad\u03bd\u03b7 IL-6 \u03ba\u03b1\u03b9 TNF-\u237a \u03c3\u03b5 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 PASC, \u03b1\u03bd \u03ba\u03b1\u03b9 \u03bf\u03b9 \u03c0\u03bf\u03bb\u03bb\u03b1\u03c0\u03bb\u03ad\u03c2 \u03b1\u03bb\u03bb\u03b1\u03b3\u03ad\u03c2 \u03c3\u03b5 \u03c3\u03cd\u03b3\u03ba\u03c1\u03b9\u03c3\u03b7 \u03bc\u03b5 \u03c4\u03bf\u03c5\u03c2 \u03b5\u03bb\u03ad\u03b3\u03c7\u03bf\u03c5\u03c2 \u03b5\u03af\u03bd\u03b1\u03b9 \u03bc\u03b9\u03ba\u03c1\u03ad\u03c2. <sup><a id=\"xref-ref-30-1\" class=\"xref-bibr\" href=\"https:\/\/www.medrxiv.org\/content\/10.1101\/2022.06.14.22276401v1.full#ref-30\">30 <\/a>, <a id=\"xref-ref-31-1\" class=\"xref-bibr\" href=\"https:\/\/www.medrxiv.org\/content\/10.1101\/2022.06.14.22276401v1.full#ref-31\">31 <\/a><\/sup>\u03a3\u03b5 \u03bc\u03b9\u03b1 \u03b4\u03b9\u03b1\u03c6\u03bf\u03c1\u03b5\u03c4\u03b9\u03ba\u03ae \u03bc\u03b5\u03bb\u03ad\u03c4\u03b7, \u03bf \u03c3\u03c5\u03bd\u03b4\u03c5\u03b1\u03c3\u03bc\u03cc\u03c2 \u03c6\u03bb\u03b5\u03b3\u03bc\u03bf\u03bd\u03c9\u03b4\u03ce\u03bd \u03bc\u03b5\u03c3\u03bf\u03bb\u03b1\u03b2\u03b7\u03c4\u03ce\u03bd, \u03c3\u03c5\u03bc\u03c0\u03b5\u03c1\u03b9\u03bb\u03b1\u03bc\u03b2\u03b1\u03bd\u03bf\u03bc\u03ad\u03bd\u03c9\u03bd \u03c4\u03c9\u03bd IL-6, IFN-\u03b3, IFN-\u03b2, PTX3 \u03ba\u03b1\u03b9 IFN-\u03bb2\/3, \u03b2\u03c1\u03ad\u03b8\u03b7\u03ba\u03b5 \u03bd\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03ad\u03bd\u03b1\u03c2 \u03c0\u03b9\u03bf \u03ba\u03b1\u03c4\u03b1\u03c4\u03bf\u03c0\u03b9\u03c3\u03c4\u03b9\u03ba\u03cc\u03c2 \u03c0\u03c1\u03bf\u03b3\u03bd\u03c9\u03c3\u03c4\u03b9\u03ba\u03cc\u03c2 \u03c0\u03b1\u03c1\u03ac\u03b3\u03bf\u03bd\u03c4\u03b1\u03c2 \u03c4\u03bf\u03c5 PASC. <sup><a id=\"xref-ref-32-1\" class=\"xref-bibr\" href=\"https:\/\/www.medrxiv.org\/content\/10.1101\/2022.06.14.22276401v1.full#ref-32\">32 <\/a><\/sup>\u0395\u03c0\u03bf\u03bc\u03ad\u03bd\u03c9\u03c2, \u03c0\u03b1\u03c1\u03cc\u03bb\u03bf \u03c0\u03bf\u03c5 \u03b4\u03b5\u03bd \u03c0\u03b1\u03c1\u03b1\u03c4\u03b7\u03c1\u03bf\u03cd\u03bc\u03b5 \u03cc\u03c4\u03b9 \u03c4\u03b1 \u03b5\u03c0\u03af\u03c0\u03b5\u03b4\u03b1 \u03ba\u03c5\u03c4\u03bf\u03ba\u03b9\u03bd\u03ce\u03bd \u03b5\u03af\u03bd\u03b1\u03b9 \u03b1\u03c5\u03be\u03b7\u03bc\u03ad\u03bd\u03b1 \u03c0\u03ac\u03bd\u03c9 \u03b1\u03c0\u03cc \u03c4\u03bf \u03c6\u03c5\u03c3\u03b9\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03cc \u03b5\u03cd\u03c1\u03bf\u03c2 \u03c3\u03c4\u03b9\u03c2 \u03c0\u03b5\u03c1\u03b9\u03c3\u03c3\u03cc\u03c4\u03b5\u03c1\u03b5\u03c2 \u03c0\u03b5\u03c1\u03b9\u03c0\u03c4\u03ce\u03c3\u03b5\u03b9\u03c2, \u03b7 \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03cd\u03b8\u03b7\u03c3\u03b7 \u03c4\u03c9\u03bd \u03ba\u03c5\u03c4\u03bf\u03ba\u03b9\u03bd\u03ce\u03bd \u03bc\u03b5 \u03c4\u03b7\u03bd \u03c0\u03ac\u03c1\u03bf\u03b4\u03bf \u03c4\u03bf\u03c5 \u03c7\u03c1\u03cc\u03bd\u03bf\u03c5 \u03c3\u03b5 \u03bc\u03b9\u03b1 \u03bc\u03b5\u03b3\u03b1\u03bb\u03cd\u03c4\u03b5\u03c1\u03b7 \u03ba\u03bf\u03cc\u03c1\u03c4\u03b7 \u03b1\u03c0\u03b1\u03b9\u03c4\u03b5\u03af \u03c0\u03b5\u03c1\u03b1\u03b9\u03c4\u03ad\u03c1\u03c9 \u03b4\u03b9\u03b5\u03c1\u03b5\u03cd\u03bd\u03b7\u03c3\u03b7. \u0395\u03c0\u03b9\u03c0\u03bb\u03ad\u03bf\u03bd, \u03b7 \u03b1\u03c0\u03bf\u03c5\u03c3\u03af\u03b1 \u03bf\u03c0\u03bf\u03b9\u03c9\u03bd\u03b4\u03ae\u03c0\u03bf\u03c4\u03b5 \u03b4\u03b9\u03b1\u03ba\u03c1\u03b9\u03c4\u03b9\u03ba\u03ce\u03bd \u03bf\u03c1\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ce\u03bd \u03c7\u03b1\u03c1\u03b1\u03ba\u03c4\u03b7\u03c1\u03b9\u03c3\u03c4\u03b9\u03ba\u03ce\u03bd \u03c3\u03c4\u03b7\u03bd \u03ba\u03bf\u03cc\u03c1\u03c4\u03b7 \u03bc\u03b1\u03c2 PASC \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03bf\u03c6\u03b5\u03af\u03bb\u03b5\u03c4\u03b1\u03b9 \u03c3\u03c4\u03bf\u03c5\u03c2 \u03ba\u03b1\u03b8\u03c5\u03c3\u03c4\u03b5\u03c1\u03b7\u03bc\u03ad\u03bd\u03bf\u03c5\u03c2 \u03c7\u03c1\u03cc\u03bd\u03bf\u03c5\u03c2 \u03b4\u03b5\u03b9\u03b3\u03bc\u03b1\u03c4\u03bf\u03bb\u03b7\u03c8\u03af\u03b1\u03c2 \u03bc\u03b5\u03c4\u03ac \u03c4\u03b7 \u03bc\u03cc\u03bb\u03c5\u03bd\u03c3\u03b7. \u039f\u03b9 \u03c7\u03b1\u03bc\u03b7\u03bb\u03cc\u03c4\u03b5\u03c1\u03bf\u03b9 \u03c4\u03af\u03c4\u03bb\u03bf\u03b9 IgM \u03ba\u03b1\u03b9 IgG3 \u03c0\u03bf\u03c5 \u03bc\u03b5\u03c4\u03c1\u03ae\u03b8\u03b7\u03ba\u03b1\u03bd \u03ba\u03b1\u03c4\u03ac \u03c4\u03b7 \u03b4\u03b9\u03ac\u03c1\u03ba\u03b5\u03b9\u03b1 \u03bf\u03be\u03b5\u03af\u03b1\u03c2 \u03bb\u03bf\u03af\u03bc\u03c9\u03be\u03b7\u03c2 \u03c3\u03c5\u03c3\u03c7\u03b5\u03c4\u03af\u03b6\u03bf\u03bd\u03c4\u03b1\u03b9 \u03bc\u03b5 \u03c4\u03b7\u03bd \u03b1\u03bd\u03ac\u03c0\u03c4\u03c5\u03be\u03b7 PASC, <sup><a id=\"xref-ref-33-1\" class=\"xref-bibr\" href=\"https:\/\/www.medrxiv.org\/content\/10.1101\/2022.06.14.22276401v1.full#ref-33\">33 <\/a><\/sup>\u03b1\u03bb\u03bb\u03ac \u03bc\u03b5 \u03c4\u03b7\u03bd \u03c0\u03ac\u03c1\u03bf\u03b4\u03bf \u03c4\u03bf\u03c5 \u03c7\u03c1\u03cc\u03bd\u03bf\u03c5 \u03c0\u03bf\u03bb\u03bb\u03ad\u03c2 \u03b1\u03bd\u03bf\u03c3\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ad\u03c2 \u03c5\u03c0\u03bf\u03b3\u03c1\u03b1\u03c6\u03ad\u03c2 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03bc\u03b5\u03b9\u03c9\u03b8\u03bf\u03cd\u03bd, <sup><a id=\"xref-ref-34-1\" class=\"xref-bibr\" href=\"https:\/\/www.medrxiv.org\/content\/10.1101\/2022.06.14.22276401v1.full#ref-34\">34 <\/a><\/sup>\u03c4\u03bf\u03bd\u03af\u03b6\u03bf\u03bd\u03c4\u03b1\u03c2 \u03c4\u03b7 \u03c3\u03b7\u03bc\u03b1\u03c3\u03af\u03b1 \u03c4\u03b7\u03c2 \u03b1\u03bd\u03ac\u03bb\u03c5\u03c3\u03b7\u03c2 \u03b4\u03b5\u03b9\u03b3\u03bc\u03ac\u03c4\u03c9\u03bd \u03b1\u03c3\u03b8\u03b5\u03bd\u03ce\u03bd \u03ba\u03bf\u03bd\u03c4\u03ac \u03c3\u03c4\u03bf\u03bd \u03c7\u03c1\u03cc\u03bd\u03bf \u03c4\u03b7\u03c2 \u03c0\u03c1\u03c9\u03c4\u03bf\u03b3\u03b5\u03bd\u03bf\u03cd\u03c2 \u03bc\u03cc\u03bb\u03c5\u03bd\u03c3\u03b7\u03c2 \u03ba\u03b1\u03b9 \u03c3\u03b5 \u03b2\u03ac\u03b8\u03bf\u03c2 \u03c7\u03c1\u03cc\u03bd\u03bf\u03c5.<\/p>\n<p id=\"p-28\">\u03a3\u03c5\u03bc\u03c0\u03b5\u03c1\u03b1\u03c3\u03bc\u03b1\u03c4\u03b9\u03ba\u03ac, \u03b7 \u03c0\u03b1\u03c1\u03bf\u03c5\u03c3\u03af\u03b1 \u03b1\u03b9\u03c7\u03bc\u03ae\u03c2 \u03c3\u03c4\u03b7\u03bd \u03ba\u03c5\u03ba\u03bb\u03bf\u03c6\u03bf\u03c1\u03af\u03b1 \u03c3\u03b5 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 PASC \u03ad\u03c9\u03c2 \u03ba\u03b1\u03b9 12 \u03bc\u03ae\u03bd\u03b5\u03c2 \u03bc\u03b5\u03c4\u03ac \u03c4\u03b7 \u03b4\u03b9\u03ac\u03b3\u03bd\u03c9\u03c3\u03b7 \u03c5\u03c0\u03bf\u03b4\u03b7\u03bb\u03ce\u03bd\u03b5\u03b9 \u03ad\u03bd\u03c4\u03bf\u03bd\u03b1 \u03cc\u03c4\u03b9 \u03bf\u03b9 \u03b4\u03b5\u03be\u03b1\u03bc\u03b5\u03bd\u03ad\u03c2 \u03c4\u03bf\u03c5 \u03b9\u03bf\u03cd SARS-CoV-2 \u03c0\u03b1\u03c1\u03b1\u03bc\u03ad\u03bd\u03bf\u03c5\u03bd \u03c3\u03c4\u03bf \u03c3\u03ce\u03bc\u03b1. \u0395\u03c0\u03b9\u03c0\u03bb\u03ad\u03bf\u03bd, \u03b7 \u03b1\u03bd\u03af\u03c7\u03bd\u03b5\u03c5\u03c3\u03b7 \u03b1\u03b9\u03c7\u03bc\u03ae\u03c2 \u03c3\u03c4\u03b7\u03bd \u03c0\u03bb\u03b5\u03b9\u03bf\u03bd\u03cc\u03c4\u03b7\u03c4\u03b1 \u03c4\u03c9\u03bd \u03b1\u03c4\u03cc\u03bc\u03c9\u03bd \u03c0\u03bf\u03c5 \u03c0\u03b5\u03c1\u03b9\u03bb\u03b1\u03bc\u03b2\u03ac\u03bd\u03bf\u03bd\u03c4\u03b1\u03b9 \u03c3\u03c4\u03b7\u03bd \u03ba\u03bf\u03cc\u03c1\u03c4\u03b7 PASC \u03bc\u03b1\u03c2 \u03c0\u03b1\u03c1\u03ad\u03c7\u03b5\u03b9 \u03b9\u03c3\u03c7\u03c5\u03c1\u03ae \u03c5\u03c0\u03bf\u03c3\u03c4\u03ae\u03c1\u03b9\u03be\u03b7 \u03b3\u03b9\u03b1 \u03c4\u03b7 \u03c7\u03c1\u03ae\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03b1\u03ba\u03af\u03b4\u03b1\u03c2 \u03c9\u03c2 \u03b2\u03b9\u03bf\u03b4\u03b5\u03af\u03ba\u03c4\u03b7 \u03b3\u03b9\u03b1 \u03c4\u03bf PASC. \u0395\u03ac\u03bd \u03bf\u03b9 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 PASC \u03bc\u03c0\u03bf\u03c1\u03bf\u03cd\u03bd \u03bd\u03b1 \u03b5\u03bd\u03c4\u03bf\u03c0\u03b9\u03c3\u03c4\u03bf\u03cd\u03bd \u03bc\u03b5 \u03b2\u03ac\u03c3\u03b7 \u03c4\u03b7\u03bd \u03ac\u03bc\u03b5\u03c3\u03b7 \u03bc\u03ad\u03c4\u03c1\u03b7\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03c0\u03c1\u03c9\u03c4\u03b5\u0390\u03bd\u03b7\u03c2 \u03b1\u03ba\u03af\u03b4\u03b1\u03c2, \u03bf \u03c7\u03b1\u03c1\u03b1\u03ba\u03c4\u03b7\u03c1\u03b9\u03c3\u03bc\u03cc\u03c2 \u03c4\u03c9\u03bd \u03c6\u03b1\u03b9\u03bd\u03bf\u03c4\u03cd\u03c0\u03c9\u03bd \u03c4\u03c9\u03bd \u03b1\u03c3\u03b8\u03b5\u03bd\u03ce\u03bd \u03ba\u03b1\u03b9 \u03b7 \u03b1\u03be\u03b9\u03bf\u03bb\u03cc\u03b3\u03b7\u03c3\u03b7 \u03c4\u03c9\u03bd \u03c3\u03c4\u03c1\u03b1\u03c4\u03b7\u03b3\u03b9\u03ba\u03ce\u03bd \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1\u03c2 \u03b8\u03b1 \u03b3\u03af\u03bd\u03bf\u03bd\u03c4\u03b1\u03b9 \u03cc\u03bb\u03bf \u03ba\u03b1\u03b9 \u03c0\u03b9\u03bf \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03b5\u03c3\u03bc\u03b1\u03c4\u03b9\u03ba\u03bf\u03af.<\/p>\n<\/div>\n<div id=\"sec-5\" class=\"section\">\n<h2 class=\"\">\u03a5\u03bb\u03b9\u03ba\u03ac \u03ba\u03b1\u03b9 \u03bc\u03ad\u03b8\u03bf\u03b4\u03bf\u03b9<\/h2>\n<div id=\"sec-6\" class=\"section\">\n<h3>\u03a3\u03c5\u03bb\u03bb\u03bf\u03b3\u03ae \u03b4\u03b5\u03b9\u03b3\u03bc\u03ac\u03c4\u03c9\u03bd<\/h3>\n<p id=\"p-31\">\u038c\u03bb\u03b1 \u03c4\u03b1 \u03ac\u03c4\u03bf\u03bc\u03b1 \u03b5\u03af\u03c7\u03b1\u03bd \u03b5\u03c0\u03b9\u03b2\u03b5\u03b2\u03b1\u03b9\u03c9\u03bc\u03ad\u03bd\u03b7 PCR \u03bb\u03bf\u03af\u03bc\u03c9\u03be\u03b7 COVID-19 \u03ba\u03b1\u03b9 \u03c3\u03c5\u03bc\u03c0\u03b5\u03c1\u03b9\u03bb\u03ae\u03c6\u03b8\u03b7\u03ba\u03b1\u03bd \u03c3\u03c4\u03bf \u03c0\u03c1\u03cc\u03b3\u03c1\u03b1\u03bc\u03bc\u03b1 \u03b2\u03b9\u03bf\u03b1\u03c0\u03bf\u03b8\u03ae\u03ba\u03b7\u03c2 \u03c4\u03b7\u03c2 \u03bc\u03b5\u03b3\u03ac\u03bb\u03b7\u03c2 \u03ba\u03bf\u03b9\u03bd\u03bf\u03c0\u03c1\u03b1\u03be\u03af\u03b1\u03c2 \u039c\u03b1\u03c3\u03b1\u03c7\u03bf\u03c5\u03c3\u03ad\u03c4\u03b7\u03c2 Coalition for Pathogen Readiness (MassCPR) \u03c3\u03c4\u03bf \u0399\u03bd\u03c3\u03c4\u03b9\u03c4\u03bf\u03cd\u03c4\u03bf Ragon. \u03a4\u03b1 \u03b4\u03b5\u03af\u03b3\u03bc\u03b1\u03c4\u03b1 \u03b3\u03b9\u03b1 \u03b1\u03c5\u03c4\u03ae \u03c4\u03b7 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b7 \u03b5\u03c0\u03b9\u03bb\u03ad\u03c7\u03b8\u03b7\u03ba\u03b1\u03bd \u03bc\u03b5 \u03b2\u03ac\u03c3\u03b7 \u03c4\u03b1 \u03b1\u03bd\u03b1\u03c6\u03b5\u03c1\u03cc\u03bc\u03b5\u03bd\u03b1 \u03c3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03b1 \u03c0\u03bf\u03c5 \u03ba\u03b1\u03c4\u03b1\u03b3\u03c1\u03ac\u03c6\u03b7\u03ba\u03b1\u03bd \u03c3\u03b5 \u03b5\u03c1\u03c9\u03c4\u03b7\u03bc\u03b1\u03c4\u03bf\u03bb\u03cc\u03b3\u03b9\u03b1 \u03b5\u03c0\u03af\u03c3\u03ba\u03b5\u03c8\u03b7\u03c2 \u03c1\u03bf\u03c5\u03c4\u03af\u03bd\u03b1\u03c2. \u03a4\u03b1 \u03ac\u03c4\u03bf\u03bc\u03b1 \u03c0\u03bf\u03c5 \u03b1\u03bd\u03ad\u03c6\u03b5\u03c1\u03b1\u03bd \u03c3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03b1 \u03b3\u03b9\u03b1 \u03c0\u03b5\u03c1\u03b9\u03c3\u03c3\u03cc\u03c4\u03b5\u03c1\u03b5\u03c2 \u03b1\u03c0\u03cc 30 \u03b7\u03bc\u03ad\u03c1\u03b5\u03c2 \u03bc\u03b5\u03c4\u03ac \u03c4\u03bf\u03bd COVID-19 \u03c3\u03c5\u03bc\u03c0\u03b5\u03c1\u03b9\u03bb\u03ae\u03c6\u03b8\u03b7\u03ba\u03b1\u03bd \u03c3\u03c4\u03b7\u03bd \u03ba\u03bf\u03cc\u03c1\u03c4\u03b7 \u03bc\u03b1\u03c2 PASC \u03ba\u03b1\u03b9 \u03c0\u03b5\u03c1\u03b9\u03bb\u03ac\u03bc\u03b2\u03b1\u03bd\u03b1\u03bd \u03ac\u03c4\u03bf\u03bc\u03b1 \u03c0\u03bf\u03c5 \u03b1\u03bd\u03ad\u03c6\u03b5\u03c1\u03b1\u03bd 1-5 \u03c0\u03b1\u03c1\u03b1\u03c4\u03b5\u03c4\u03b1\u03bc\u03ad\u03bd\u03b1 \u03c3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03b1, \u03cc\u03c0\u03c9\u03c2 \u03b1\u03bd\u03bf\u03c3\u03bc\u03af\u03b1, \u03ba\u03cc\u03c0\u03c9\u03c3\u03b7, \u03bf\u03bc\u03af\u03c7\u03bb\u03b7 \u03b5\u03b3\u03ba\u03b5\u03c6\u03ac\u03bb\u03bf\u03c5, \u03b5\u03c0\u03af\u03bc\u03bf\u03bd\u03bf \u03b2\u03ae\u03c7\u03b1, \u03b5\u03c0\u03af\u03bc\u03bf\u03bd\u03bf\u03c5\u03c2 \u03c0\u03bf\u03bd\u03bf\u03ba\u03b5\u03c6\u03ac\u03bb\u03bf\u03c5\u03c2 \u03ba.\u03bb\u03c0. \u03a4\u03b1 \u03b4\u03b5\u03af\u03b3\u03bc\u03b1\u03c4\u03b1 \u03c3\u03c5\u03bb\u03bb\u03ad\u03c7\u03b8\u03b7\u03ba\u03b1\u03bd \u03c3\u03b5\u03b9\u03c1\u03b9\u03b1\u03ba\u03ac \u03ad\u03c9\u03c2 360 \u03b7\u03bc\u03ad\u03c1\u03b5\u03c2 \u03bc\u03b5\u03c4\u03ac \u03c4\u03b7\u03bd \u03b5\u03c0\u03b9\u03b2\u03b5\u03b2\u03b1\u03b9\u03c9\u03bc\u03ad\u03bd\u03b7 \u03bb\u03bf\u03af\u03bc\u03c9\u03be\u03b7 \u03b1\u03c0\u03cc \u03c4\u03bf\u03bd SARS-CoV-2 \u03bc\u03b5 PCR. \u0395\u03c0\u03b9\u03c0\u03bb\u03ad\u03bf\u03bd, \u03bf\u03b9 \u03bc\u03ac\u03c1\u03c4\u03c5\u03c1\u03b5\u03c2 \u03c0\u03bf\u03c5 \u03b4\u03b5\u03bd \u03ae\u03c4\u03b1\u03bd PASC \u03c0\u03b5\u03c1\u03b9\u03b5\u03bb\u03ac\u03bc\u03b2\u03b1\u03bd\u03b1\u03bd \u03b5\u03c0\u03b9\u03b2\u03b5\u03b2\u03b1\u03b9\u03c9\u03bc\u03ad\u03bd\u03bf\u03c5\u03c2 \u03bc\u03b5 PCR \u03b1\u03bd\u03ac\u03c1\u03c1\u03c9\u03c3\u03b7 \u03b1\u03c0\u03cc COVID-19 \u03c7\u03c9\u03c1\u03af\u03c2 \u03b1\u03bd\u03b1\u03c6\u03b5\u03c1\u03cc\u03bc\u03b5\u03bd\u03b1 \u03c0\u03b1\u03c1\u03b1\u03c4\u03b5\u03c4\u03b1\u03bc\u03ad\u03bd\u03b1 \u03c3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03b1 \u03c0\u03bf\u03c5 \u03bb\u03ae\u03c6\u03b8\u03b7\u03ba\u03b1\u03bd \u03bc\u03b5\u03c4\u03ac \u03c4\u03b7 \u03b4\u03b9\u03ac\u03b3\u03bd\u03c9\u03c3\u03b7. \u038c\u03bb\u03b1 \u03c4\u03b1 \u03ac\u03c4\u03bf\u03bc\u03b1 \u03ad\u03b4\u03c9\u03c3\u03b1\u03bd \u03b5\u03bd\u03b7\u03bc\u03b5\u03c1\u03c9\u03bc\u03ad\u03bd\u03b7 \u03c3\u03c5\u03b3\u03ba\u03b1\u03c4\u03ac\u03b8\u03b5\u03c3\u03b7 \u03ba\u03b1\u03b9 \u03b7 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b7 \u03b5\u03b3\u03ba\u03c1\u03af\u03b8\u03b7\u03ba\u03b5 \u03b1\u03c0\u03cc \u03c4\u03bf \u0393\u03b5\u03bd\u03b9\u03ba\u03cc \u039d\u03bf\u03c3\u03bf\u03ba\u03bf\u03bc\u03b5\u03af\u03bf Brigham \u03c4\u03b7\u03c2 \u039c\u03b1\u03c3\u03b1\u03c7\u03bf\u03c5\u03c3\u03ad\u03c4\u03b7\u03c2. \u0394\u03b5\u03af\u03b3\u03bc\u03b1\u03c4\u03b1 \u03c0\u03bb\u03ac\u03c3\u03bc\u03b1\u03c4\u03bf\u03c2 \u03b1\u03c0\u03cc 16 \u03b5\u03c0\u03b9\u03c0\u03bb\u03ad\u03bf\u03bd \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 COVID-19 \u03b5\u03bb\u03ae\u03c6\u03b8\u03b7\u03c3\u03b1\u03bd \u03b1\u03c0\u03cc \u03c4\u03b7 Mass General Brigham Biobank. \u03a4\u03b1 \u03b4\u03b7\u03bc\u03bf\u03b3\u03c1\u03b1\u03c6\u03b9\u03ba\u03ac \u03c3\u03c4\u03bf\u03b9\u03c7\u03b5\u03af\u03b1 \u03c4\u03c9\u03bd \u03b1\u03c3\u03b8\u03b5\u03bd\u03ce\u03bd \u03ba\u03b1\u03b9 \u03bf\u03b9 \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ad\u03c2 \u03c0\u03bb\u03b7\u03c1\u03bf\u03c6\u03bf\u03c1\u03af\u03b5\u03c2 \u03b5\u03be\u03ae\u03c7\u03b8\u03b7\u03c3\u03b1\u03bd \u03b1\u03c0\u03cc \u03b7\u03bb\u03b5\u03ba\u03c4\u03c1\u03bf\u03bd\u03b9\u03ba\u03ac \u03b9\u03b1\u03c4\u03c1\u03b9\u03ba\u03ac \u03b1\u03c1\u03c7\u03b5\u03af\u03b1. \u0397 \u03b1\u03bd\u03ac\u03bb\u03c5\u03c3\u03b7 \u03b4\u03b5\u03b9\u03b3\u03bc\u03ac\u03c4\u03c9\u03bd \u03c0\u03bb\u03ac\u03c3\u03bc\u03b1\u03c4\u03bf\u03c2 COVID-19 \u03b5\u03b3\u03ba\u03c1\u03af\u03b8\u03b7\u03ba\u03b5 \u03b1\u03c0\u03cc \u03c4\u03bf \u03a3\u03c5\u03bc\u03b2\u03bf\u03cd\u03bb\u03b9\u03bf \u0398\u03b5\u03c3\u03bc\u03b9\u03ba\u03ae\u03c2 \u0391\u03bd\u03b1\u03b8\u03b5\u03ce\u03c1\u03b7\u03c3\u03b7\u03c2 \u03c4\u03bf\u03c5 \u039d\u03bf\u03c3\u03bf\u03ba\u03bf\u03bc\u03b5\u03af\u03bf\u03c5 Brigham and Women&#8217;s Hospital.<\/p>\n<\/div>\n<div id=\"sec-7\" class=\"section\">\n<h3>\u0394\u03bf\u03ba\u03b9\u03bc\u03b1\u03c3\u03af\u03b5\u03c2 \u03b1\u03bd\u03c4\u03b9\u03b3\u03cc\u03bd\u03bf\u03c5 Simoa SARS-CoV-2<\/h3>\n<p id=\"p-32\">\u03a4\u03b1 \u03b1\u03bd\u03c4\u03b9\u03b3\u03cc\u03bd\u03b1 SARS-CoV-2 S1, \u03b1\u03ba\u03af\u03b4\u03b1 \u03ba\u03b1\u03b9 \u039d \u03bc\u03b5\u03c4\u03c1\u03ae\u03b8\u03b7\u03ba\u03b1\u03bd \u03c3\u03b5 \u03b4\u03b5\u03af\u03b3\u03bc\u03b1\u03c4\u03b1 \u03c0\u03bb\u03ac\u03c3\u03bc\u03b1\u03c4\u03bf\u03c2 \u03c7\u03c1\u03b7\u03c3\u03b9\u03bc\u03bf\u03c0\u03bf\u03b9\u03ce\u03bd\u03c4\u03b1\u03c2 \u03c0\u03c1\u03bf\u03b7\u03b3\u03bf\u03c5\u03bc\u03ad\u03bd\u03c9\u03c2 \u03b1\u03bd\u03b1\u03c0\u03c4\u03c5\u03b3\u03bc\u03ad\u03bd\u03b7 \u03c3\u03c5\u03c3\u03c4\u03bf\u03b9\u03c7\u03af\u03b1 \u03bc\u03b5\u03bc\u03bf\u03bd\u03c9\u03bc\u03ad\u03bd\u03c9\u03bd \u03bc\u03bf\u03c1\u03af\u03c9\u03bd (Simoa). <sup><a id=\"xref-ref-18-2\" class=\"xref-bibr\" href=\"https:\/\/www.medrxiv.org\/content\/10.1101\/2022.06.14.22276401v1.full#ref-18\">18 <\/a>, <a id=\"xref-ref-19-2\" class=\"xref-bibr\" href=\"https:\/\/www.medrxiv.org\/content\/10.1101\/2022.06.14.22276401v1.full#ref-19\">19 <\/a><\/sup>\u03b4\u03b5\u03af\u03b3\u03bc\u03b1\u03c4\u03b1 \u03c0\u03bb\u03ac\u03c3\u03bc\u03b1\u03c4\u03bf\u03c2 \u03c0\u03c1\u03ce\u03c4\u03b1 \u03b5\u03c0\u03c9\u03ac\u03c3\u03c4\u03b7\u03ba\u03b1\u03bd \u03bc\u03b5 \u03b4\u03b9\u03b8\u03b5\u03b9\u03bf\u03b8\u03c1\u03b5\u03ca\u03c4\u03cc\u03bb\u03b7 (DTT) \u03ba\u03b1\u03b9 \u03b1\u03bd\u03b1\u03c3\u03c4\u03bf\u03bb\u03b5\u03af\u03c2 \u03c0\u03c1\u03c9\u03c4\u03b5\u03ac\u03c3\u03b7\u03c2 (Halt Protease Inhibitor Cocktail, ThermoFisher) \u03c3\u03c4\u03bf\u03c5\u03c2 37 \u00b0C \u03b3\u03b9\u03b1 15 \u03bb\u03b5\u03c0\u03c4\u03ac \u03b3\u03b9\u03b1 \u03bd\u03b1 \u03bc\u03b5\u03c4\u03bf\u03c5\u03c3\u03b9\u03c9\u03b8\u03bf\u03cd\u03bd \u03c4\u03c5\u03c7\u03cc\u03bd \u03b4\u03b5\u03c3\u03bc\u03b5\u03c5\u03bc\u03ad\u03bd\u03b1 \u03b1\u03bd\u03c4\u03b9\u03c3\u03ce\u03bc\u03b1\u03c4\u03b1. \u03a4\u03b1 \u03b4\u03b5\u03af\u03b3\u03bc\u03b1\u03c4\u03b1 \u03c3\u03c4\u03b7 \u03c3\u03c5\u03bd\u03ad\u03c7\u03b5\u03b9\u03b1 \u03b1\u03c1\u03b1\u03b9\u03ce\u03b8\u03b7\u03ba\u03b1\u03bd 8 \u03c6\u03bf\u03c1\u03ad\u03c2 \u03c3\u03b5 \u03ad\u03bd\u03b1 \u03c1\u03c5\u03b8\u03bc\u03b9\u03c3\u03c4\u03b9\u03ba\u03cc \u03b4\u03b9\u03ac\u03bb\u03c5\u03bc\u03b1 \u03b1\u03c1\u03b1\u03b9\u03c9\u03c4\u03b9\u03ba\u03bf\u03cd \u03b4\u03b5\u03af\u03b3\u03bc\u03b1\u03c4\u03bf\u03c2 (Quanterix Corp.) \u03ba\u03b1\u03b9 \u03bf\u03b9 \u03b4\u03bf\u03ba\u03b9\u03bc\u03b1\u03c3\u03af\u03b5\u03c2 \u03b4\u03b9\u03b5\u03be\u03ae\u03c7\u03b8\u03b7\u03c3\u03b1\u03bd \u03c7\u03c1\u03b7\u03c3\u03b9\u03bc\u03bf\u03c0\u03bf\u03b9\u03ce\u03bd\u03c4\u03b1\u03c2 \u03ad\u03bd\u03b1\u03bd \u03b1\u03bd\u03b1\u03bb\u03c5\u03c4\u03ae HD-X (Quanterix Corp.).<\/p>\n<\/div>\n<div id=\"sec-8\" class=\"section\">\n<h3>\u039a\u03c5\u03c4\u03bf\u03ba\u03af\u03bd\u03b5\u03c2<\/h3>\n<p id=\"p-33\">\u03a4\u03b1 \u03b5\u03c0\u03af\u03c0\u03b5\u03b4\u03b1 \u03ba\u03c5\u03c4\u03bf\u03ba\u03af\u03bd\u03b7\u03c2 \u03bc\u03b5\u03c4\u03c1\u03ae\u03b8\u03b7\u03ba\u03b1\u03bd \u03c3\u03b5 \u03b4\u03b5\u03af\u03b3\u03bc\u03b1\u03c4\u03b1 \u03c0\u03bb\u03ac\u03c3\u03bc\u03b1\u03c4\u03bf\u03c2 \u03c7\u03c1\u03b7\u03c3\u03b9\u03bc\u03bf\u03c0\u03bf\u03b9\u03ce\u03bd\u03c4\u03b1\u03c2 \u03c4\u03bf\u03bd \u03c0\u03af\u03bd\u03b1\u03ba\u03b1 \u03ba\u03c5\u03c4\u03bf\u03ba\u03b9\u03bd\u03ce\u03bd CorPlex (Quanterix Corp). \u03a4\u03b1 \u03b4\u03b5\u03af\u03b3\u03bc\u03b1\u03c4\u03b1 \u03c0\u03bb\u03ac\u03c3\u03bc\u03b1\u03c4\u03bf\u03c2 \u03b1\u03c1\u03b1\u03b9\u03ce\u03b8\u03b7\u03ba\u03b1\u03bd 4 \u03c6\u03bf\u03c1\u03ad\u03c2 \u03c3\u03b5 \u03c1\u03c5\u03b8\u03bc\u03b9\u03c3\u03c4\u03b9\u03ba\u03cc \u03b4\u03b9\u03ac\u03bb\u03c5\u03bc\u03b1 \u03b1\u03c1\u03b1\u03b9\u03c9\u03c4\u03b9\u03ba\u03bf\u03cd \u03b4\u03b5\u03af\u03b3\u03bc\u03b1\u03c4\u03bf\u03c2 \u03ba\u03b1\u03b9 \u03c0\u03c1\u03b1\u03b3\u03bc\u03b1\u03c4\u03bf\u03c0\u03bf\u03b9\u03ae\u03b8\u03b7\u03ba\u03b1\u03bd \u03b1\u03bd\u03b1\u03bb\u03cd\u03c3\u03b5\u03b9\u03c2 \u03c3\u03cd\u03bc\u03c6\u03c9\u03bd\u03b1 \u03bc\u03b5 \u03c4\u03b1 \u03c0\u03c1\u03c9\u03c4\u03cc\u03ba\u03bf\u03bb\u03bb\u03b1 \u03c4\u03bf\u03c5 \u03ba\u03b1\u03c4\u03b1\u03c3\u03ba\u03b5\u03c5\u03b1\u03c3\u03c4\u03ae CorPlex. \u039a\u03ac\u03b8\u03b5 \u03ba\u03b9\u03c4 \u03c0\u03af\u03bd\u03b1\u03ba\u03b1 \u03ba\u03c5\u03c4\u03bf\u03ba\u03af\u03bd\u03b7\u03c2 CorPlex \u03b1\u03bd\u03b1\u03bb\u03cd\u03b8\u03b7\u03ba\u03b5 \u03b1\u03c0\u03cc \u03c4\u03bf SP-X Imaging and Analysis System (Quanterix Corp.).<\/p>\n<\/div>\n<\/div>\n<div id=\"ack-1\" class=\"section ack\">\n<h2 class=\"\">\u0395\u03c5\u03c7\u03b1\u03c1\u03b9\u03c3\u03c4\u03af\u03b5\u03c2<\/h2>\n<p id=\"p-30\">\u0397 \u03c7\u03c1\u03b7\u03bc\u03b1\u03c4\u03bf\u03b4\u03cc\u03c4\u03b7\u03c3\u03b7 \u03b3\u03b9\u03b1 \u03b1\u03c5\u03c4\u03cc \u03c4\u03bf \u03ad\u03c1\u03b3\u03bf \u03c0\u03c1\u03bf\u03ae\u03bb\u03b8\u03b5 \u03b1\u03c0\u03cc \u03bc\u03b9\u03b1 \u03b3\u03b5\u03bd\u03bd\u03b1\u03b9\u03cc\u03b4\u03c9\u03c1\u03b7 \u03b4\u03c9\u03c1\u03b5\u03ac \u03b1\u03c0\u03cc \u03c4\u03b7 Barbara and Amos Hostetter. \u0395\u03c5\u03c7\u03b1\u03c1\u03b9\u03c3\u03c4\u03bf\u03cd\u03bc\u03b5 \u03c4\u03b7\u03bd \u03ba\u03bf\u03b9\u03bd\u03bf\u03c0\u03c1\u03b1\u03be\u03af\u03b1 MassCPR PASC \u03ba\u03b1\u03b9 \u03c4\u03b7\u03bd \u03bf\u03bc\u03ac\u03b4\u03b1 Ragon Institute\/MassCPR Biobank \u03b3\u03b9\u03b1 \u03c4\u03b7\u03bd \u03bf\u03b9\u03ba\u03bf\u03bd\u03bf\u03bc\u03b9\u03ba\u03ae \u03c5\u03c0\u03bf\u03c3\u03c4\u03ae\u03c1\u03b9\u03be\u03b7 \u03ba\u03b1\u03b9 \u03c4\u03b7\u03bd \u03c5\u03c0\u03bf\u03c3\u03c4\u03ae\u03c1\u03b9\u03be\u03b7 \u03c4\u03b7\u03c2 \u03b5\u03c0\u03b5\u03be\u03b5\u03c1\u03b3\u03b1\u03c3\u03af\u03b1\u03c2 \u03b4\u03b5\u03b9\u03b3\u03bc\u03ac\u03c4\u03c9\u03bd.<\/p>\n<\/div>\n<div id=\"ref-list-1\" class=\"section ref-list\">\n<h2 class=\"\">\u03b2\u03b9\u03b2\u03bb\u03b9\u03bf\u03b3\u03c1\u03b1\u03c6\u03b9\u03ba\u03ad\u03c2 \u03b1\u03bd\u03b1\u03c6\u03bf\u03c1\u03ad\u03c2<\/h2>\n<ol class=\"cit-list ref-use-labels\">\n<li><span class=\"ref-label\">1. <\/span><a id=\"ref-1\" class=\"rev-xref-ref\" title=\"\u03a0\u03c1\u03bf\u03b2\u03bf\u03bb\u03ae \u03b1\u03bd\u03b1\u03c6\u03bf\u03c1\u03ac\u03c2 1. \u03c3\u03b5 \u03ba\u03b5\u03af\u03bc\u03b5\u03bd\u03bf\" href=\"https:\/\/www.medrxiv.org\/content\/10.1101\/2022.06.14.22276401v1.full#xref-ref-1-1\">\u21b5 <\/a>\n<div id=\"cit-2022.06.14.22276401v1.1\" class=\"cit ref-cit ref-journal google_scholar_link-processed custom-js-processed\" data-doi=\"10.1016\/S0140-6736(20)32656-8\">\n<div class=\"cit-metadata\"><cite><span class=\"cit-auth\"><span class=\"cit-name-surname\">Huang <\/span> <span class=\"cit-name-given-names\">C <\/span><\/span>, <span class=\"cit-auth\"><span class=\"cit-name-surname\">Huang <\/span> <span class=\"cit-name-given-names\">L <\/span><\/span>, <span class=\"cit-auth\"><span class=\"cit-name-surname\">Wang <\/span> <span class=\"cit-name-given-names\">\u03a5 <\/span><\/span>, <span class=\"cit-etal\">et \u03b1\u03ca. <\/span> <span class=\"cit-article-title\">\u03a3\u03c5\u03bd\u03ad\u03c0\u03b5\u03b9\u03b5\u03c2 6 \u03bc\u03b7\u03bd\u03ce\u03bd \u03c4\u03bf\u03c5 COVID-19 \u03c3\u03b5 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03c0\u03bf\u03c5 \u03b5\u03be\u03ae\u03bb\u03b8\u03b1\u03bd \u03b1\u03c0\u03cc \u03c4\u03bf \u03bd\u03bf\u03c3\u03bf\u03ba\u03bf\u03bc\u03b5\u03af\u03bf: \u03bc\u03b9\u03b1 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b7 \u03ba\u03bf\u03cc\u03c1\u03c4\u03b7\u03c2 <\/span>. <abbr class=\"cit-jnl-abbrev\">\u03a4\u03bf Lancet <\/abbr>. <span class=\"cit-pub-date\">2021 <\/span>; <span class=\"cit-vol\">397 <\/span>( <span class=\"cit-issue\">10270 <\/span>): <span class=\"cit-fpage\">220 <\/span>\u2013 <span class=\"cit-lpage\">232 <\/span>. <span class=\"cit-pub-id-scheme\">doi: <\/span><span class=\"cit-pub-id cit-pub-id-doi\">10.1016\/S0140-6736(20)32656-8 <\/span><\/cite><\/div>\n<div class=\"cit-extra\"><a class=\"cit-ref-sprinkles cit-ref-sprinkles-doi cit-ref-sprinkles-crossref\" href=\"https:\/\/www.medrxiv.org\/lookup\/external-ref?access_num=10.1016\/S0140-6736(20)32656-8&amp;link_type=DOI\">CrossRef <\/a><a class=\"cit-ref-sprinkles cit-ref-sprinkles-medline\" href=\"https:\/\/www.medrxiv.org\/lookup\/external-ref?access_num=http:\/\/www.n&amp;link_type=MED&amp;atom=%2Fmedrxiv%2Fearly%2F2022%2F06%2F16%2F2022.06.14.22276401.atom\">PubMed <\/a><a class=\"cit-ref-sprinkles cit-ref-sprinkles-google-scholar cit-ref-sprinkles-google-scholar\" href=\"https:\/\/www.medrxiv.org\/lookup\/google-scholar?link_type=googlescholar&amp;gs_type=article&amp;author[0]=C+Huang&amp;author[1]=L+Huang&amp;author[2]=Y+Wang&amp;title=6-month+consequences+of+COVID-19+in+patients+discharged+from+hospital:+a+cohort+study&amp;publication_year=2021&amp;journal=The+Lancet&amp;volume=397&amp;pages=220-232\">Google Scholar <\/a><\/div>\n<\/div>\n<\/li>\n<li><span class=\"ref-label\">2. <\/span>\n<div id=\"cit-2022.06.14.22276401v1.2\" class=\"cit ref-cit ref-journal no-rev-xref google_scholar_link-processed custom-js-processed\" data-doi=\"10.1001\/jamanetworkopen.2021.0830\">\n<div class=\"cit-metadata\"><cite><span class=\"cit-auth\"><span class=\"cit-name-surname\">Logue <\/span> <span class=\"cit-name-given-names\">JK <\/span><\/span>, <span class=\"cit-auth\"><span class=\"cit-name-surname\">Franko <\/span> <span class=\"cit-name-given-names\">NM <\/span><\/span>, <span class=\"cit-auth\"><span class=\"cit-name-surname\">McCulloch <\/span> <span class=\"cit-name-given-names\">DJ <\/span><\/span>, <span class=\"cit-etal\">et al. <\/span> <span class=\"cit-article-title\">\u03b1\u03c0\u03cc COVID-19 <\/span>\u03bc\u03cc\u03bb\u03c5\u03bd\u03c3\u03b7 <abbr class=\"cit-jnl-abbrev\">JAMA Network <\/abbr>Open <span class=\"cit-pub-date\">2021 <\/span>; <span class=\"cit-vol\">4 <\/span>( <span class=\"cit-issue\">2 <\/span>): <span class=\"cit-fpage\">e210830 <\/span>. <span class=\"cit-pub-id-scheme\">doi: <\/span><span class=\"cit-pub-id cit-pub-id-doi\">10.1001\/\u03b5\u03b8\u03bd\u03b9\u03ba\u03cc \u03b4\u03af\u03ba\u03c4\u03c5\u03bf.2021.0830 <\/span><\/cite><\/div>\n<div class=\"cit-extra\"><a class=\"cit-ref-sprinkles cit-ref-sprinkles-doi cit-ref-sprinkles-crossref\" href=\"https:\/\/www.medrxiv.org\/lookup\/external-ref?access_num=10.1001\/jamanetworkopen.2021.0830&amp;link_type=DOI\">CrossRef <\/a><a class=\"cit-ref-sprinkles cit-ref-sprinkles-google-scholar cit-ref-sprinkles-google-scholar\" href=\"https:\/\/www.medrxiv.org\/lookup\/google-scholar?link_type=googlescholar&amp;gs_type=article&amp;author[0]=JK+Logue&amp;author[1]=NM+Franko&amp;author[2]=DJ+McCulloch&amp;title=Sequelae+in+Adults+at+6+Months+After+COVID-19+Infection&amp;publication_year=2021&amp;journal=JAMA+Netw+Open&amp;volume=4\">Google Scholar <\/a><\/div>\n<\/div>\n<\/li>\n<li><span class=\"ref-label\">3. <\/span>\n<div id=\"cit-2022.06.14.22276401v1.3\" class=\"cit ref-cit ref-journal no-rev-xref google_scholar_link-processed custom-js-processed\" data-doi=\"10.1136\/bmjopen-2020-048391\">\n<div class=\"cit-metadata\"><cite><span class=\"cit-auth\"><span class=\"cit-name-surname\">Dennis <\/span> <span class=\"cit-name-given-names\">A <\/span><\/span>, <span class=\"cit-auth\"><span class=\"cit-name-surname\">Wamil <\/span> <span class=\"cit-name-given-names\">M <\/span><\/span>, <span class=\"cit-auth\"><span class=\"cit-name-surname\">Alberts <\/span> <span class=\"cit-name-given-names\">J <\/span><\/span>, <span class=\"cit-etal\">et al. <\/span> <span class=\"cit-article-title\">\u03a0\u03bf\u03bb\u03c5\u03bf\u03c1\u03b3\u03b1\u03bd\u03b9\u03ba\u03ae \u03b4\u03c5\u03c3\u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03af\u03b1 \u03c3\u03b5 \u03ac\u03c4\u03bf\u03bc\u03b1 \u03c7\u03b1\u03bc\u03b7\u03bb\u03bf\u03cd \u03ba\u03b9\u03bd\u03b4\u03cd\u03bd\u03bf\u03c5 \u03bc\u03b5 \u03c3\u03cd\u03bd\u03b4\u03c1\u03bf\u03bc\u03bf \u03bc\u03b5\u03c4\u03ac \u03c4\u03b7\u03bd COVID-19: \u03bc\u03b9\u03b1 \u03c0\u03c1\u03bf\u03bf\u03c0\u03c4\u03b9\u03ba\u03ae, \u03b2\u03b1\u03c3\u03b9\u03c3\u03bc\u03ad\u03bd\u03b7 \u03c3\u03c4\u03b7\u03bd \u03ba\u03bf\u03b9\u03bd\u03cc\u03c4\u03b7\u03c4\u03b1 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b7 <\/span>. <abbr class=\"cit-jnl-abbrev\">BMJ Open <\/abbr>. <span class=\"cit-pub-date\">2021 <\/span>; <span class=\"cit-vol\">11 <\/span>( <span class=\"cit-issue\">3 <\/span>): <span class=\"cit-fpage\">e048391 <\/span>. <span class=\"cit-pub-id-scheme\">doi: <\/span><span class=\"cit-pub-id cit-pub-id-doi\">10.1136\/bmjopen-2020-048391 <\/span><\/cite><\/div>\n<div class=\"cit-extra\"><a class=\"cit-ref-sprinkles cit-ref-sprinkles-ijlink\" href=\"https:\/\/www.medrxiv.org\/lookup\/ijlink\/YTozOntzOjQ6InBhdGgiO3M6MTQ6Ii9sb29rdXAvaWpsaW5rIjtzOjU6InF1ZXJ5IjthOjQ6e3M6ODoibGlua1R5cGUiO3M6NDoiQUJTVCI7czoxMToiam91cm5hbENvZGUiO3M6NzoiYm1qb3BlbiI7czo1OiJyZXNpZCI7czoxMjoiMTEvMy9lMDQ4MzkxIjtzOjQ6ImF0b20iO3M6NTA6Ii9tZWRyeGl2L2Vhcmx5LzIwMjIvMDYvMTYvMjAyMi4wNi4xNC4yMjI3NjQwMS5hdG9tIjt9czo4OiJmcmFnbWVudCI7czowOiIiO30=\"><span class=\"cit-reflinks-abstract\">Abstract <\/span><span class=\"cit-sep cit-reflinks-variant-name-sep\">\/ <\/span><span class=\"cit-reflinks-full-text\"><span class=\"free-full-text\">\u0394\u03a9\u03a1\u0395\u0391\u039d <\/span>Full Text <\/span><\/a><a class=\"cit-ref-sprinkles cit-ref-sprinkles-google-scholar cit-ref-sprinkles-google-scholar\" href=\"https:\/\/www.medrxiv.org\/lookup\/google-scholar?link_type=googlescholar&amp;gs_type=article&amp;author[0]=A+Dennis&amp;author[1]=M+Wamil&amp;author[2]=J+Alberts&amp;title=Multiorgan+impairment+in+low-risk+individuals+with+post-COVID-19+syndrome:+a+prospective,+community-based+study&amp;publication_year=2021&amp;journal=BMJ+Open&amp;volume=11\">Google Scholar <\/a><\/div>\n<\/div>\n<\/li>\n<li><span class=\"ref-label\">4. <\/span>\n<div id=\"cit-2022.06.14.22276401v1.4\" class=\"cit ref-cit ref-journal no-rev-xref google_scholar_link-processed custom-js-processed\" data-doi=\"10.1038\/s41591-021-01283-z\">\n<div class=\"cit-metadata\"><cite><span class=\"cit-auth\"><span class=\"cit-name-surname\">Nalbandian <\/span> <span class=\"cit-name-given-names\">A <\/span><\/span>, <span class=\"cit-auth\"><span class=\"cit-name-surname\">Sehgal <\/span> <span class=\"cit-name-given-names\">K <\/span><\/span>, <span class=\"cit-auth\"><span class=\"cit-name-surname\">Gupta <\/span> <span class=\"cit-name-given-names\">A <\/span><\/span>, <span class=\"cit-etal\">et al. <\/span> <span class=\"cit-article-title\">\u039c\u03b5\u03c4\u03b1-\u03bf\u03be\u03cd \u03c3\u03cd\u03bd\u03b4\u03c1\u03bf\u03bc\u03bf COVID-19 <\/span>. <abbr class=\"cit-jnl-abbrev\">Nat Med <\/abbr>. <span class=\"cit-pub-date\">2021 <\/span>; <span class=\"cit-vol\">27 <\/span>( <span class=\"cit-issue\">4 <\/span>): <span class=\"cit-fpage\">601 <\/span>&#8211; <span class=\"cit-lpage\">615 <\/span>. <span class=\"cit-pub-id-scheme\">doi: <\/span><span class=\"cit-pub-id cit-pub-id-doi\">10.1038 \/ s41591-021-01283-z <\/span><\/cite><\/div>\n<div class=\"cit-extra\"><a class=\"cit-ref-sprinkles cit-ref-sprinkles-doi cit-ref-sprinkles-crossref\" href=\"https:\/\/www.medrxiv.org\/lookup\/external-ref?access_num=10.1038\/s41591-021-01283-z&amp;link_type=DOI\">CrossRef <\/a><a class=\"cit-ref-sprinkles cit-ref-sprinkles-medline\" href=\"https:\/\/www.medrxiv.org\/lookup\/external-ref?access_num=33753937&amp;link_type=MED&amp;atom=%2Fmedrxiv%2Fearly%2F2022%2F06%2F16%2F2022.06.14.22276401.atom\">PubMed <\/a><a class=\"cit-ref-sprinkles cit-ref-sprinkles-google-scholar cit-ref-sprinkles-google-scholar\" href=\"https:\/\/www.medrxiv.org\/lookup\/google-scholar?link_type=googlescholar&amp;gs_type=article&amp;author[0]=A+Nalbandian&amp;author[1]=K+Sehgal&amp;author[2]=A+Gupta&amp;title=Post-acute+COVID-19+syndrome&amp;publication_year=2021&amp;journal=Nat+Med&amp;volume=27&amp;pages=601-615\">Google Scholar <\/a><\/div>\n<\/div>\n<\/li>\n<li><span class=\"ref-label\">5. <\/span>\n<div id=\"cit-2022.06.14.22276401v1.5\" class=\"cit ref-cit ref-journal no-rev-xref google_scholar_link-processed custom-js-processed\" data-doi=\"10.1038\/s41591-021-01433-3\">\n<div class=\"cit-metadata\"><cite><span class=\"cit-auth\"><span class=\"cit-name-surname\">Blomberg <\/span> <span class=\"cit-name-given-names\">\u0392 <\/span><\/span>, <span class=\"cit-auth\"><span class=\"cit-name-surname\">Mohn <\/span> <span class=\"cit-name-given-names\">KGI <\/span><\/span>, <span class=\"cit-auth\"><span class=\"cit-name-surname\">Brokstad <\/span> <span class=\"cit-name-given-names\">\u039a\u0391 <\/span><\/span>, <span class=\"cit-etal\">et al. <\/span> <span class=\"cit-article-title\">\u039c\u03b1\u03ba\u03c1\u03cd\u03c2 COVID \u03c3\u03b5 \u03bc\u03b9\u03b1 \u03c0\u03b9\u03b8\u03b1\u03bd\u03ae \u03bf\u03bc\u03ac\u03b4\u03b1 \u03b1\u03c3\u03b8\u03b5\u03bd\u03ce\u03bd \u03c0\u03bf\u03c5 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b1\u03c0\u03bf\u03bc\u03bf\u03bd\u03c9\u03bc\u03ad\u03bd\u03bf\u03b9 \u03c3\u03c4\u03bf \u03c3\u03c0\u03af\u03c4\u03b9 <\/span>. <abbr class=\"cit-jnl-abbrev\">Nat Med <\/abbr>. <span class=\"cit-pub-date\">2021 <\/span>; <span class=\"cit-vol\">27 <\/span>( <span class=\"cit-issue\">9 <\/span>): <span class=\"cit-fpage\">1607 <\/span>\u2013 <span class=\"cit-lpage\">1613 <\/span>. <span class=\"cit-pub-id-scheme\">doi: <\/span><span class=\"cit-pub-id cit-pub-id-doi\">10.1038\/s41591-021-01433-3 <\/span><\/cite><\/div>\n<div class=\"cit-extra\"><a class=\"cit-ref-sprinkles cit-ref-sprinkles-doi cit-ref-sprinkles-crossref\" href=\"https:\/\/www.medrxiv.org\/lookup\/external-ref?access_num=10.1038\/s41591-021-01433-3&amp;link_type=DOI\">CrossRef <\/a><a class=\"cit-ref-sprinkles cit-ref-sprinkles-medline\" href=\"https:\/\/www.medrxiv.org\/lookup\/external-ref?access_num=34163090&amp;link_type=MED&amp;atom=%2Fmedrxiv%2Fearly%2F2022%2F06%2F16%2F2022.06.14.22276401.atom\">PubMed <\/a><a class=\"cit-ref-sprinkles cit-ref-sprinkles-google-scholar cit-ref-sprinkles-google-scholar\" href=\"https:\/\/www.medrxiv.org\/lookup\/google-scholar?link_type=googlescholar&amp;gs_type=article&amp;author[0]=B+Blomberg&amp;author[1]=KGI+Mohn&amp;author[2]=KA+Brokstad&amp;title=Long+COVID+in+a+prospective+cohort+of+home-isolated+patients&amp;publication_year=2021&amp;journal=Nat+Med&amp;volume=27&amp;pages=1607-1613\">Google Scholar <\/a><\/div>\n<\/div>\n<\/li>\n<li><span class=\"ref-label\">6. <\/span>\n<div id=\"cit-2022.06.14.22276401v1.6\" class=\"cit ref-cit ref-journal no-rev-xref google_scholar_link-processed custom-js-processed\" data-doi=\"10.1038\/s41586-021-03553-9\">\n<div class=\"cit-metadata\"><cite><span class=\"cit-auth\"><span class=\"cit-name-surname\">Al-Aly <\/span> <span class=\"cit-name-given-names\">Z <\/span><\/span>, <span class=\"cit-auth\"><span class=\"cit-name-surname\">Xie <\/span> <span class=\"cit-name-given-names\">Y <\/span><\/span>, <span class=\"cit-auth\"><span class=\"cit-name-surname\">Bowe <\/span> <span class=\"cit-name-given-names\">B. <\/span><\/span> <span class=\"cit-article-title\">\u03a7\u03b1\u03c1\u03b1\u03ba\u03c4\u03b7\u03c1\u03b9\u03c3\u03bc\u03cc\u03c2 \u03c5\u03c8\u03b7\u03bb\u03ce\u03bd \u03b4\u03b9\u03b1\u03c3\u03c4\u03ac\u03c3\u03b5\u03c9\u03bd \u03bc\u03b5\u03c4\u03b1-\u03bf\u03be\u03ad\u03c9\u03bd \u03b5\u03c0\u03b1\u03ba\u03cc\u03bb\u03bf\u03c5\u03b8\u03c9\u03bd \u03c4\u03bf\u03c5 COVID-19 <\/span>. <abbr class=\"cit-jnl-abbrev\">\u03a6\u03cd\u03c3\u03b7 <\/abbr>. <span class=\"cit-pub-date\">2021 <\/span>; <span class=\"cit-vol\">594 <\/span>( <span class=\"cit-issue\">7862 <\/span>): <span class=\"cit-fpage\">259 <\/span>\u2013 <span class=\"cit-lpage\">264 <\/span>. <span class=\"cit-pub-id-scheme\">doi: <\/span><span class=\"cit-pub-id cit-pub-id-doi\">10.1038\/s41586-021-03553-9 <\/span><\/cite><\/div>\n<div class=\"cit-extra\"><a class=\"cit-ref-sprinkles cit-ref-sprinkles-doi cit-ref-sprinkles-crossref\" href=\"https:\/\/www.medrxiv.org\/lookup\/external-ref?access_num=10.1038\/s41586-021-03553-9&amp;link_type=DOI\">CrossRef <\/a><a class=\"cit-ref-sprinkles cit-ref-sprinkles-medline\" href=\"https:\/\/www.medrxiv.org\/lookup\/external-ref?access_num=33887749&amp;link_type=MED&amp;atom=%2Fmedrxiv%2Fearly%2F2022%2F06%2F16%2F2022.06.14.22276401.atom\">PubMed <\/a><a class=\"cit-ref-sprinkles cit-ref-sprinkles-google-scholar cit-ref-sprinkles-google-scholar\" href=\"https:\/\/www.medrxiv.org\/lookup\/google-scholar?link_type=googlescholar&amp;gs_type=article&amp;author[0]=Z+Al-Aly&amp;author[1]=Y+Xie&amp;author[2]=B.+Bowe&amp;title=High-dimensional+characterization+of+post-acute+sequelae+of+COVID-19&amp;publication_year=2021&amp;journal=Nature&amp;volume=594&amp;pages=259-264\">Google Scholar <\/a><\/div>\n<\/div>\n<\/li>\n<li><span class=\"ref-label\">7. <\/span><a id=\"ref-7\" class=\"rev-xref-ref\" title=\"\u0394\u03b5\u03af\u03c4\u03b5 \u03c4\u03b7\u03bd \u03b1\u03bd\u03b1\u03c6\u03bf\u03c1\u03ac 7. \u03c3\u03b5 \u03ba\u03b5\u03af\u03bc\u03b5\u03bd\u03bf\" href=\"https:\/\/www.medrxiv.org\/content\/10.1101\/2022.06.14.22276401v1.full#xref-ref-7-1\">\u21b5 <\/a>\n<div id=\"cit-2022.06.14.22276401v1.7\" class=\"cit ref-cit ref-journal google_scholar_link-processed custom-js-processed\" data-doi=\"10.1093\/cid\/ciaa1750\">\n<div class=\"cit-metadata\"><cite><span class=\"cit-auth\"><span class=\"cit-name-surname\">van den Borst <\/span> <span class=\"cit-name-given-names\">B <\/span><\/span>, <span class=\"cit-auth\"><span class=\"cit-name-surname\">Peters <\/span> <span class=\"cit-name-given-names\">JB <\/span><\/span>, <span class=\"cit-auth\"><span class=\"cit-name-surname\">Brink <\/span> <span class=\"cit-name-given-names\">M <\/span><\/span>, <span class=\"cit-etal\">et al. <\/span> <span class=\"cit-article-title\">\u039f\u03bb\u03bf\u03ba\u03bb\u03b7\u03c1\u03c9\u03bc\u03ad\u03bd\u03b7 \u03b1\u03be\u03b9\u03bf\u03bb\u03cc\u03b3\u03b7\u03c3\u03b7 \u03c5\u03b3\u03b5\u03af\u03b1\u03c2 3 \u03bc\u03ae\u03bd\u03b5\u03c2 \u03bc\u03b5\u03c4\u03ac \u03c4\u03b7\u03bd \u03b1\u03bd\u03ac\u03c1\u03c1\u03c9\u03c3\u03b7 \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd \u03bf\u03be\u03b5\u03af\u03b1 \u03bd\u03cc\u03c3\u03bf \u03c4\u03bf\u03c5 \u03ba\u03bf\u03c1\u03bf\u03bd\u03b1\u03ca\u03bf\u03cd 2019 (COVID-19) <\/span>. <abbr class=\"cit-jnl-abbrev\">Clin Infect Dis <\/abbr>. <span class=\"cit-pub-date\">2021 <\/span>; <span class=\"cit-vol\">73 <\/span>( <span class=\"cit-issue\">5 <\/span>): <span class=\"cit-fpage\">e1089 <\/span>\u2013 <span class=\"cit-lpage\">e1098 <\/span>. <span class=\"cit-pub-id-scheme\">doi: <\/span><span class=\"cit-pub-id cit-pub-id-doi\">10.1093\/cid\/ciaa1750 <\/span><\/cite><\/div>\n<div class=\"cit-extra\"><a class=\"cit-ref-sprinkles cit-ref-sprinkles-doi cit-ref-sprinkles-crossref\" href=\"https:\/\/www.medrxiv.org\/lookup\/external-ref?access_num=10.1093\/cid\/ciaa1750&amp;link_type=DOI\">CrossRef <\/a><a class=\"cit-ref-sprinkles cit-ref-sprinkles-medline\" href=\"https:\/\/www.medrxiv.org\/lookup\/external-ref?access_num=http:\/\/www.n&amp;link_type=MED&amp;atom=%2Fmedrxiv%2Fearly%2F2022%2F06%2F16%2F2022.06.14.22276401.atom\">PubMed <\/a><a class=\"cit-ref-sprinkles cit-ref-sprinkles-google-scholar cit-ref-sprinkles-google-scholar\" href=\"https:\/\/www.medrxiv.org\/lookup\/google-scholar?link_type=googlescholar&amp;gs_type=article&amp;author[0]=B+van den Borst&amp;author[1]=JB+Peters&amp;author[2]=M+Brink&amp;title=Comprehensive+Health+Assessment+3+Months+After+Recovery+From+Acute+Coronavirus+Disease+2019+(COVID-19)&amp;publication_year=2021&amp;journal=Clin+Infect+Dis&amp;volume=73&amp;pages=e1089-e1098\">Google Scholar <\/a><\/div>\n<\/div>\n<\/li>\n<li><span class=\"ref-label\">8. <\/span><a id=\"ref-8\" class=\"rev-xref-ref\" title=\"\u03a0\u03c1\u03bf\u03b2\u03bf\u03bb\u03ae \u03b1\u03bd\u03b1\u03c6\u03bf\u03c1\u03ac\u03c2 8. \u03c3\u03b5 \u03ba\u03b5\u03af\u03bc\u03b5\u03bd\u03bf\" href=\"https:\/\/www.medrxiv.org\/content\/10.1101\/2022.06.14.22276401v1.full#xref-ref-8-1\">\u21b5 <\/a>\n<div id=\"cit-2022.06.14.22276401v1.8\" class=\"cit ref-cit ref-journal google_scholar_link-processed custom-js-processed\" data-doi=\"10.1001\/jamanetworkopen.2021.28568\">\n<div class=\"cit-metadata\"><cite><span class=\"cit-auth\"><span class=\"cit-name-surname\">Groff <\/span> <span class=\"cit-name-given-names\">D <\/span><\/span>, <span class=\"cit-auth\"><span class=\"cit-name-surname\">Sun <\/span> <span class=\"cit-name-given-names\">A <\/span><\/span>, <span class=\"cit-auth\"><span class=\"cit-name-surname\">Ssentongo <\/span> <span class=\"cit-name-given-names\">AE <\/span><\/span>, <span class=\"cit-etal\">et al. <\/span> <span class=\"cit-article-title\">\u0392\u03c1\u03b1\u03c7\u03c5\u03c0\u03c1\u03cc\u03b8\u03b5\u03c3\u03bc\u03b1 \u03ba\u03b1\u03b9 \u03bc\u03b1\u03ba\u03c1\u03bf\u03c0\u03c1\u03cc\u03b8\u03b5\u03c3\u03bc\u03b1 \u03c0\u03bf\u03c3\u03bf\u03c3\u03c4\u03ac \u03bc\u03b5\u03c4\u03b1-\u03bf\u03be\u03ad\u03c9\u03bd \u03b5\u03c0\u03b1\u03ba\u03cc\u03bb\u03bf\u03c5\u03b8\u03c9\u03bd \u03bc\u03cc\u03bb\u03c5\u03bd\u03c3\u03b7\u03c2 \u03b1\u03c0\u03cc SARS-CoV-2: \u039c\u03b9\u03b1 \u03c3\u03c5\u03c3\u03c4\u03b7\u03bc\u03b1\u03c4\u03b9\u03ba\u03ae \u03b1\u03bd\u03b1\u03c3\u03ba\u03cc\u03c0\u03b7\u03c3\u03b7 <\/span>. <abbr class=\"cit-jnl-abbrev\">JAMA Netw Open <\/abbr>. <span class=\"cit-pub-date\">2021 <\/span>; <span class=\"cit-vol\">4 <\/span>( <span class=\"cit-issue\">10 <\/span>): <span class=\"cit-fpage\">e2128568 <\/span>. <span class=\"cit-pub-id-scheme\">doi: <\/span><span class=\"cit-pub-id cit-pub-id-doi\">10.1001\/jamanetworkopen.2021.28568 <\/span><\/cite><\/div>\n<div class=\"cit-extra\"><a class=\"cit-ref-sprinkles cit-ref-sprinkles-doi cit-ref-sprinkles-crossref\" href=\"https:\/\/www.medrxiv.org\/lookup\/external-ref?access_num=10.1001\/jamanetworkopen.2021.28568&amp;link_type=DOI\">CrossRef <\/a><a class=\"cit-ref-sprinkles cit-ref-sprinkles-medline\" href=\"https:\/\/www.medrxiv.org\/lookup\/external-ref?access_num=34643720&amp;link_type=MED&amp;atom=%2Fmedrxiv%2Fearly%2F2022%2F06%2F16%2F2022.06.14.22276401.atom\">PubMed <\/a><a class=\"cit-ref-sprinkles cit-ref-sprinkles-google-scholar cit-ref-sprinkles-google-scholar\" href=\"https:\/\/www.medrxiv.org\/lookup\/google-scholar?link_type=googlescholar&amp;gs_type=article&amp;author[0]=D+Groff&amp;author[1]=A+Sun&amp;author[2]=AE+Ssentongo&amp;title=Short-term+and+Long-term+Rates+of+Postacute+Sequelae+of+SARS-CoV-2+Infection:+A+Systematic+Review&amp;publication_year=2021&amp;journal=JAMA+Netw+Open&amp;volume=4\">Google Scholar <\/a><\/div>\n<\/div>\n<\/li>\n<li><span class=\"ref-label\">9. <\/span>\n<div id=\"cit-2022.06.14.22276401v1.9\" class=\"cit ref-cit ref-journal no-rev-xref google_scholar_link-processed custom-js-processed\" data-doi=\"10.1038\/s41467-021-26513-3\">\n<div class=\"cit-metadata\"><cite><span class=\"cit-auth\"><span class=\"cit-name-surname\">Xie <\/span> <span class=\"cit-name-given-names\">Y <\/span><\/span>, <span class=\"cit-auth\"><span class=\"cit-name-surname\">Bowe <\/span> <span class=\"cit-name-given-names\">B <\/span><\/span>, <span class=\"cit-auth\"><span class=\"cit-name-surname\">Al-Aly <\/span> <span class=\"cit-name-given-names\">Z. <\/span><\/span> <span class=\"cit-article-title\">\u0395\u03c0\u03b9\u03b2\u03b1\u03c1\u03cd\u03bd\u03c3\u03b5\u03b9\u03c2 \u03bc\u03b5\u03c4\u03b1-\u03bf\u03be\u03ad\u03c9\u03bd \u03b5\u03c0\u03b1\u03ba\u03cc\u03bb\u03bf\u03c5\u03b8\u03c9\u03bd \u03c4\u03bf\u03c5 COVID-19 \u03ba\u03b1\u03c4\u03ac \u03c3\u03bf\u03b2\u03b1\u03c1\u03cc\u03c4\u03b7\u03c4\u03b1 \u03bf\u03be\u03b5\u03af\u03b1\u03c2 \u03bb\u03bf\u03af\u03bc\u03c9\u03be\u03b7\u03c2, \u03b4\u03b7\u03bc\u03bf\u03b3\u03c1\u03b1\u03c6\u03b9\u03ba\u03ac \u03c3\u03c4\u03bf\u03b9\u03c7\u03b5\u03af\u03b1 \u03ba\u03b1\u03b9 \u03ba\u03b1\u03c4\u03ac\u03c3\u03c4\u03b1\u03c3\u03b7 \u03c5\u03b3\u03b5\u03af\u03b1\u03c2 <\/span>. <abbr class=\"cit-jnl-abbrev\">Nat Commun <\/abbr>. <span class=\"cit-pub-date\">2021 <\/span>; <span class=\"cit-vol\">12 <\/span>( <span class=\"cit-issue\">1 <\/span>): <span class=\"cit-fpage\">6571 <\/span>. <span class=\"cit-pub-id-scheme\">doi: <\/span><span class=\"cit-pub-id cit-pub-id-doi\">10.1038\/s41467-021-26513-3 <\/span><\/cite><\/div>\n<div class=\"cit-extra\"><a class=\"cit-ref-sprinkles cit-ref-sprinkles-doi cit-ref-sprinkles-crossref\" href=\"https:\/\/www.medrxiv.org\/lookup\/external-ref?access_num=10.1038\/s41467-021-26513-3&amp;link_type=DOI\">CrossRef <\/a><a class=\"cit-ref-sprinkles cit-ref-sprinkles-medline\" href=\"https:\/\/www.medrxiv.org\/lookup\/external-ref?access_num=34772922&amp;link_type=MED&amp;atom=%2Fmedrxiv%2Fearly%2F2022%2F06%2F16%2F2022.06.14.22276401.atom\">PubMed <\/a><a class=\"cit-ref-sprinkles cit-ref-sprinkles-google-scholar cit-ref-sprinkles-google-scholar\" href=\"https:\/\/www.medrxiv.org\/lookup\/google-scholar?link_type=googlescholar&amp;gs_type=article&amp;author[0]=Y+Xie&amp;author[1]=B+Bowe&amp;author[2]=Z.+Al-Aly&amp;title=Burdens+of+post-acute+sequelae+of+COVID-19+by+severity+of+acute+infection,+demographics+and+health+status&amp;publication_year=2021&amp;journal=Nat+Commun&amp;volume=12\">Google Scholar <\/a><\/div>\n<\/div>\n<\/li>\n<li><span class=\"ref-label\">10. <\/span>\n<div id=\"cit-2022.06.14.22276401v1.10\" class=\"cit ref-cit ref-journal no-rev-xref google_scholar_link-processed custom-js-processed\" data-doi=\"10.1093\/cid\/ciab408\">\n<div class=\"cit-metadata\"><cite><span class=\"cit-auth\"><span class=\"cit-name-surname\">Hirschtick <\/span> <span class=\"cit-name-given-names\">JL <\/span><\/span>, <span class=\"cit-auth\"><span class=\"cit-name-surname\">Titus <\/span> <span class=\"cit-name-given-names\">AR <\/span><\/span>, <span class=\"cit-auth\"><span class=\"cit-name-surname\">Slocum <\/span> <span class=\"cit-name-given-names\">E <\/span><\/span>, <span class=\"cit-etal\">et al. <\/span> <span class=\"cit-article-title\">\u0395\u03ba\u03c4\u03b9\u03bc\u03ae\u03c3\u03b5\u03b9\u03c2 \u03bc\u03b5 \u03b2\u03ac\u03c3\u03b7 \u03c4\u03bf\u03bd \u03c0\u03bb\u03b7\u03b8\u03c5\u03c3\u03bc\u03cc \u03c4\u03c9\u03bd \u03bc\u03b5\u03c4\u03b1-\u03bf\u03be\u03ad\u03c9\u03bd \u03b5\u03c0\u03b1\u03ba\u03cc\u03bb\u03bf\u03c5\u03b8\u03c9\u03bd \u03c4\u03bf\u03c5 \u03c3\u03bf\u03b2\u03b1\u03c1\u03bf\u03cd \u03bf\u03be\u03ad\u03bf\u03c2 \u03b1\u03bd\u03b1\u03c0\u03bd\u03b5\u03c5\u03c3\u03c4\u03b9\u03ba\u03bf\u03cd \u03c3\u03c5\u03bd\u03b4\u03c1\u03cc\u03bc\u03bf\u03c5 \u03bc\u03cc\u03bb\u03c5\u03bd\u03c3\u03b7\u03c2 \u03b1\u03c0\u03cc \u03c4\u03bf\u03bd \u03ba\u03bf\u03c1\u03bf\u03bd\u03bf\u03ca\u03cc 2 (SARS-CoV-2) (PASC) \u0395\u03c0\u03b9\u03c0\u03bf\u03bb\u03b1\u03c3\u03bc\u03cc\u03c2 \u03ba\u03b1\u03b9 \u03c7\u03b1\u03c1\u03b1\u03ba\u03c4\u03b7\u03c1\u03b9\u03c3\u03c4\u03b9\u03ba\u03ac <\/span>. <abbr class=\"cit-jnl-abbrev\">Clin Infect Dis <\/abbr>. <span class=\"cit-pub-date\">2021 <\/span>; <span class=\"cit-vol\">73 <\/span>( <span class=\"cit-issue\">11 <\/span>): <span class=\"cit-fpage\">2055 <\/span>\u2013 <span class=\"cit-lpage\">2064 <\/span>. <span class=\"cit-pub-id-scheme\">doi: <\/span><span class=\"cit-pub-id cit-pub-id-doi\">10.1093\/cid\/ciab408 <\/span><\/cite><\/div>\n<div class=\"cit-extra\"><a class=\"cit-ref-sprinkles cit-ref-sprinkles-doi cit-ref-sprinkles-crossref\" href=\"https:\/\/www.medrxiv.org\/lookup\/external-ref?access_num=10.1093\/cid\/ciab408&amp;link_type=DOI\">CrossRef <\/a><a class=\"cit-ref-sprinkles cit-ref-sprinkles-medline\" href=\"https:\/\/www.medrxiv.org\/lookup\/external-ref?access_num=34007978&amp;link_type=MED&amp;atom=%2Fmedrxiv%2Fearly%2F2022%2F06%2F16%2F2022.06.14.22276401.atom\">PubMed <\/a><a class=\"cit-ref-sprinkles cit-ref-sprinkles-google-scholar cit-ref-sprinkles-google-scholar\" href=\"https:\/\/www.medrxiv.org\/lookup\/google-scholar?link_type=googlescholar&amp;gs_type=article&amp;author[0]=JL+Hirschtick&amp;author[1]=AR+Titus&amp;author[2]=E+Slocum&amp;title=Population-Based+Estimates+of+Post-acute+Sequelae+of+Severe+Acute+Respiratory+Syndrome+Coronavirus+2+(SARS-CoV-2)+Infection+(PASC)+Prevalence+and+Characteristics&amp;publication_year=2021&amp;journal=Clin+Infect+Dis&amp;volume=73&amp;pages=2055-2064\">Google Scholar <\/a><\/div>\n<\/div>\n<\/li>\n<li><span class=\"ref-label\">11. <\/span><a id=\"ref-11\" class=\"rev-xref-ref\" title=\"\u03a0\u03c1\u03bf\u03b2\u03bf\u03bb\u03ae \u03b1\u03bd\u03b1\u03c6\u03bf\u03c1\u03ac\u03c2 11. \u03c3\u03b5 \u03ba\u03b5\u03af\u03bc\u03b5\u03bd\u03bf\" href=\"https:\/\/www.medrxiv.org\/content\/10.1101\/2022.06.14.22276401v1.full#xref-ref-11-1\">\u21b5 <\/a>\n<div id=\"cit-2022.06.14.22276401v1.11\" class=\"cit ref-cit ref-journal google_scholar_link-processed custom-js-processed\" data-doi=\"10.1038\/s41467-022-29521-z\">\n<div class=\"cit-metadata\"><cite><span class=\"cit-auth\"><span class=\"cit-name-surname\">Whitaker <\/span> <span class=\"cit-name-given-names\">\u039c <\/span><\/span>, <span class=\"cit-auth\"><span class=\"cit-name-surname\">Elliott <\/span> <span class=\"cit-name-given-names\">J <\/span><\/span>, <span class=\"cit-auth\"><span class=\"cit-name-surname\">Chadeau-Hyam <\/span> <span class=\"cit-name-given-names\">\u039c <\/span><\/span>, <span class=\"cit-etal\">et al. <\/span> <span class=\"cit-article-title\">\u0395\u03c0\u03af\u03bc\u03bf\u03bd\u03b1 \u03c3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03b1 COVID-19 \u03c3\u03b5 \u03bc\u03b9\u03b1 \u03ba\u03bf\u03b9\u03bd\u03bf\u03c4\u03b9\u03ba\u03ae \u03bc\u03b5\u03bb\u03ad\u03c4\u03b7 606.434 \u03b1\u03c4\u03cc\u03bc\u03c9\u03bd \u03c3\u03c4\u03b7\u03bd \u0391\u03b3\u03b3\u03bb\u03af\u03b1 <\/span>. <abbr class=\"cit-jnl-abbrev\">Nat Commun <\/abbr>. <span class=\"cit-pub-date\">2022 <\/span>; <span class=\"cit-vol\">13 <\/span>( <span class=\"cit-issue\">1 <\/span>): <span class=\"cit-fpage\">1957 <\/span>. <span class=\"cit-pub-id-scheme\">doi: <\/span><span class=\"cit-pub-id cit-pub-id-doi\">10.1038\/s41467-022-29521-z <\/span><\/cite><\/div>\n<div class=\"cit-extra\"><a class=\"cit-ref-sprinkles cit-ref-sprinkles-doi cit-ref-sprinkles-crossref\" href=\"https:\/\/www.medrxiv.org\/lookup\/external-ref?access_num=10.1038\/s41467-022-29521-z&amp;link_type=DOI\">CrossRef <\/a><a class=\"cit-ref-sprinkles cit-ref-sprinkles-google-scholar cit-ref-sprinkles-google-scholar\" href=\"https:\/\/www.medrxiv.org\/lookup\/google-scholar?link_type=googlescholar&amp;gs_type=article&amp;author[0]=M+Whitaker&amp;author[1]=J+Elliott&amp;author[2]=M+Chadeau-Hyam&amp;title=Persistent+COVID-19+symptoms+in+a+community+study+of+606,434+people+in+England&amp;publication_year=2022&amp;journal=Nat+Commun&amp;volume=13\">Google Scholar <\/a><\/div>\n<\/div>\n<\/li>\n<li><span class=\"ref-label\">12. <\/span><a id=\"ref-12\" class=\"rev-xref-ref\" title=\"\u0394\u03b5\u03af\u03c4\u03b5 \u03c4\u03b7\u03bd \u03b1\u03bd\u03b1\u03c6\u03bf\u03c1\u03ac 12. \u03c3\u03b5 \u03ba\u03b5\u03af\u03bc\u03b5\u03bd\u03bf\" href=\"https:\/\/www.medrxiv.org\/content\/10.1101\/2022.06.14.22276401v1.full#xref-ref-12-1\">\u21b5 <\/a>\n<div id=\"cit-2022.06.14.22276401v1.12\" class=\"cit ref-cit ref-web google_scholar_link-processed custom-js-processed\">\n<div class=\"cit-metadata\"><cite><span class=\"cit-auth cit-collab\">\u03a0\u03b1\u03b3\u03ba\u03cc\u03c3\u03bc\u03b9\u03bf\u03c2 \u039f\u03c1\u03b3\u03b1\u03bd\u03b9\u03c3\u03bc\u03cc\u03c2 \u03a5\u03b3\u03b5\u03af\u03b1\u03c2 (\u03a0\u039f\u03a5) <\/span>. <span class=\"cit-source\">\u03a3\u03c4\u03bf\u03bd \u03b1\u03c0\u03cc\u03b7\u03c7\u03bf \u03c4\u03b7\u03c2 \u03c0\u03b1\u03bd\u03b4\u03b7\u03bc\u03af\u03b1\u03c2: \u03c0\u03c1\u03bf\u03b5\u03c4\u03bf\u03b9\u03bc\u03b1\u03c3\u03af\u03b1 \u03b3\u03b9\u03b1 \u03c4\u03bf Long COVID <\/span>( <span class=\"cit-pub-date\">2021 <\/span>). \u03a0\u03c1\u03cc\u03c3\u03b2\u03b1\u03c3\u03b7 <span class=\"cit-date-in-citation\">\u03c3\u03c4\u03b9\u03c2 11 \u039c\u03b1\u0390\u03bf\u03c5 2022 <\/span>. <a href=\"https:\/\/www.euro.who.int\/en\/health-topics\/health-emergencies\/coronavirus-covid-19\/publications-and-technical-guidance\/2021\/in-the-wake-of-the-pandemic-preparing-for-long-covid-2021\">https:\/\/www.euro.who.int\/en\/health-topics\/health-emergencies\/coronavirus-covid-19\/publications-and-technical-guidance\/2021\/in-the-wake-of-the-pandemic- \u03c0\u03c1\u03bf\u03b5\u03c4\u03bf\u03b9\u03bc\u03b1\u03c3\u03af\u03b1-\u03b3\u03b9\u03b1-\u03bc\u03b1\u03ba\u03c1\u03bf\u03c7\u03c1\u03cc\u03bd\u03b9\u03b1-covid-2021 <\/a><\/cite><\/div>\n<div class=\"cit-extra\"><a class=\"cit-ref-sprinkles cit-ref-sprinkles-google-scholar cit-ref-sprinkles-google-scholar\" href=\"https:\/\/www.medrxiv.org\/lookup\/google-scholar?link_type=googlescholar&amp;gs_type=article&amp;q_txt=World+Health+Organization+(WHO).+In+the+wake+of+the+pandemic%3A+preparing+for+Long+COVID+(2021).+Accessed+May+11%2C+2022.+https%3A%2F%2Fwww.euro.who.int%2Fen%2Fhealth-topics%2Fhealth-emergencies%2Fcoronavirus-covid-19%2Fpublications-and-technical-guidance%2F2021%2Fin-the-wake-of-the-pandemic-preparing-for-long-covid-2021\">\u039c\u03b5\u03bb\u03b5\u03c4\u03b7\u03c4\u03ae\u03c2 Google <\/a><\/div>\n<\/div>\n<\/li>\n<li><span class=\"ref-label\">13. <\/span><a id=\"ref-13\" class=\"rev-xref-ref\" title=\"\u0394\u03b5\u03af\u03c4\u03b5 \u03c4\u03b7\u03bd \u03b1\u03bd\u03b1\u03c6\u03bf\u03c1\u03ac 13. \u03c3\u03b5 \u03ba\u03b5\u03af\u03bc\u03b5\u03bd\u03bf\" href=\"https:\/\/www.medrxiv.org\/content\/10.1101\/2022.06.14.22276401v1.full#xref-ref-13-1\">\u21b5 <\/a>\n<div id=\"cit-2022.06.14.22276401v1.13\" class=\"cit ref-cit ref-journal google_scholar_link-processed custom-js-processed\" data-doi=\"10.1016\/j.it.2022.02.008\">\n<div class=\"cit-metadata\"><cite><span class=\"cit-auth\"><span class=\"cit-name-surname\">Peluso <\/span> <span class=\"cit-name-given-names\">MJ <\/span><\/span>, <span class=\"cit-auth\"><span class=\"cit-name-surname\">Deeks <\/span> <span class=\"cit-name-given-names\">SG <\/span><\/span>. <span class=\"cit-article-title\">\u03a0\u03c1\u03ce\u03b9\u03bc\u03b5\u03c2 \u03b5\u03bd\u03b4\u03b5\u03af\u03be\u03b5\u03b9\u03c2 \u03c3\u03c7\u03b5\u03c4\u03b9\u03ba\u03ac \u03bc\u03b5 \u03c4\u03b7\u03bd \u03c0\u03b1\u03b8\u03bf\u03b3\u03ad\u03bd\u03b5\u03c3\u03b7 \u03c4\u03bf\u03c5 \u03bc\u03b1\u03ba\u03c1\u03bf\u03c7\u03c1\u03cc\u03bd\u03b9\u03bf\u03c5 COVID <\/span>. <abbr class=\"cit-jnl-abbrev\">Trends Immunol <\/abbr>. <span class=\"cit-pub-date\">2022 <\/span>; <span class=\"cit-vol\">43 <\/span>( <span class=\"cit-issue\">4 <\/span>): <span class=\"cit-fpage\">268 <\/span>\u2013 <span class=\"cit-lpage\">270 <\/span>. <span class=\"cit-pub-id-scheme\">doi: <\/span><span class=\"cit-pub-id cit-pub-id-doi\">10.1016\/j.it.2022.02.008 <\/span><\/cite><\/div>\n<div class=\"cit-extra\"><a class=\"cit-ref-sprinkles cit-ref-sprinkles-doi cit-ref-sprinkles-crossref\" href=\"https:\/\/www.medrxiv.org\/lookup\/external-ref?access_num=10.1016\/j.it.2022.02.008&amp;link_type=DOI\">CrossRef <\/a><a class=\"cit-ref-sprinkles cit-ref-sprinkles-google-scholar cit-ref-sprinkles-google-scholar\" href=\"https:\/\/www.medrxiv.org\/lookup\/google-scholar?link_type=googlescholar&amp;gs_type=article&amp;author[0]=MJ+Peluso&amp;author[1]=SG+Deeks&amp;title=Early+clues+regarding+the+pathogenesis+of+long-COVID&amp;publication_year=2022&amp;journal=Trends+Immunol&amp;volume=43&amp;pages=268-270\">Google Scholar <\/a><\/div>\n<\/div>\n<\/li>\n<li><span class=\"ref-label\">14. <\/span><a id=\"ref-14\" class=\"rev-xref-ref\" title=\"\u03a0\u03c1\u03bf\u03b2\u03bf\u03bb\u03ae \u03b1\u03bd\u03b1\u03c6\u03bf\u03c1\u03ac\u03c2 14. \u03c3\u03b5 \u03ba\u03b5\u03af\u03bc\u03b5\u03bd\u03bf\" href=\"https:\/\/www.medrxiv.org\/content\/10.1101\/2022.06.14.22276401v1.full#xref-ref-14-1\">\u21b5 <\/a>\n<div id=\"cit-2022.06.14.22276401v1.14\" class=\"cit ref-cit ref-journal google_scholar_link-processed custom-js-processed\" data-doi=\"10.1016\/j.mayocp.2021.11.033\">\n<div class=\"cit-metadata\"><cite><span class=\"cit-auth\"><span class=\"cit-name-surname\">Ganesh <\/span> <span class=\"cit-name-given-names\">R <\/span><\/span>, <span class=\"cit-auth\"><span class=\"cit-name-surname\">Grach <\/span> <span class=\"cit-name-given-names\">SL <\/span><\/span>, <span class=\"cit-auth\"><span class=\"cit-name-surname\">Ghosh <\/span> <span class=\"cit-name-given-names\">AK <\/span><\/span>, <span class=\"cit-etal\">et \u03b1\u03ca. <\/span> <span class=\"cit-article-title\">\u0397 \u0395\u03c0\u03af\u03bc\u03bf\u03bd\u03b7 \u0391\u03bd\u03bf\u03c3\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ae \u0394\u03c5\u03c3\u03c1\u03c1\u03cd\u03b8\u03bc\u03b9\u03c3\u03b7 \u03c4\u03b7\u03c2 \u0395\u03c0\u03b9\u03ba\u03c1\u03b1\u03c4\u03bf\u03cd\u03c3\u03b1\u03c2 \u0393\u03c5\u03bd\u03b1\u03af\u03ba\u03b1\u03c2 \u03c4\u03bf\u03c5 \u039c\u03b5\u03c4\u03b1-COVID \u03a3\u03c5\u03bd\u03b4\u03c1\u03cc\u03bc\u03bf\u03c5 <\/span>. <abbr class=\"cit-jnl-abbrev\">Mayo Clin Proc <\/abbr>. <span class=\"cit-pub-date\">2022 <\/span>; <span class=\"cit-vol\">97 <\/span>( <span class=\"cit-issue\">3 <\/span>) <span class=\"cit-fpage\">454\u2013464 <\/span>: <span class=\"cit-lpage\">_ <\/span>. <span class=\"cit-pub-id-scheme\">doi: <\/span><span class=\"cit-pub-id cit-pub-id-doi\">10.1016\/j.mayocp.2021.11.033 <\/span><\/cite><\/div>\n<div class=\"cit-extra\"><a class=\"cit-ref-sprinkles cit-ref-sprinkles-doi cit-ref-sprinkles-crossref\" href=\"https:\/\/www.medrxiv.org\/lookup\/external-ref?access_num=10.1016\/j.mayocp.2021.11.033&amp;link_type=DOI\">CrossRef <\/a><a class=\"cit-ref-sprinkles cit-ref-sprinkles-google-scholar cit-ref-sprinkles-google-scholar\" href=\"https:\/\/www.medrxiv.org\/lookup\/google-scholar?link_type=googlescholar&amp;gs_type=article&amp;author[0]=R+Ganesh&amp;author[1]=SL+Grach&amp;author[2]=AK+Ghosh&amp;title=The+Female-Predominant+Persistent+Immune+Dysregulation+of+the+Post-COVID+Syndrome&amp;publication_year=2022&amp;journal=Mayo+Clin+Proc&amp;volume=97&amp;pages=454-464\">Google Scholar <\/a><\/div>\n<\/div>\n<\/li>\n<li><span class=\"ref-label\">15. <\/span>\n<div id=\"cit-2022.06.14.22276401v1.15\" class=\"cit ref-cit ref-journal no-rev-xref google_scholar_link-processed custom-js-processed\" data-doi=\"10.1080\/23744235.2021.1965210\">\n<div class=\"cit-metadata\"><cite><span class=\"cit-auth\"><span class=\"cit-name-surname\">Lindahl <\/span> <span class=\"cit-name-given-names\">A <\/span><\/span>, <span class=\"cit-auth\"><span class=\"cit-name-surname\">Aro <\/span> <span class=\"cit-name-given-names\">M <\/span><\/span>, <span class=\"cit-auth\"><span class=\"cit-name-surname\">Reijula <\/span> <span class=\"cit-name-given-names\">\u200b\u200bJ <\/span><\/span>, <span class=\"cit-etal\">et al. <\/span> <span class=\"cit-article-title\">\u039f\u03b9 \u03b3\u03c5\u03bd\u03b1\u03af\u03ba\u03b5\u03c2 \u03b1\u03bd\u03b1\u03c6\u03ad\u03c1\u03bf\u03c5\u03bd \u03c0\u03b5\u03c1\u03b9\u03c3\u03c3\u03cc\u03c4\u03b5\u03c1\u03b1 \u03c3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03b1 \u03ba\u03b1\u03b9 \u03bc\u03b5\u03b9\u03c9\u03bc\u03ad\u03bd\u03b7 \u03c0\u03bf\u03b9\u03cc\u03c4\u03b7\u03c4\u03b1 \u03b6\u03c9\u03ae\u03c2: \u03ad\u03c1\u03b5\u03c5\u03bd\u03b1 \u03a6\u03b9\u03bd\u03bb\u03b1\u03bd\u03b4\u03ce\u03bd \u03b5\u03c0\u03b9\u03b6\u03ce\u03bd\u03c4\u03c9\u03bd \u03c4\u03bf\u03c5 COVID-19 <\/span>. <abbr class=\"cit-jnl-abbrev\">Infect Dis <\/abbr>. <span class=\"cit-pub-date\">2022 <\/span>; <span class=\"cit-vol\">54 <\/span>( <span class=\"cit-issue\">1 <\/span>): <span class=\"cit-fpage\">53 <\/span>\u2013 <span class=\"cit-lpage\">62 <\/span>. <span class=\"cit-pub-id-scheme\">doi: <\/span><span class=\"cit-pub-id cit-pub-id-doi\">10.1080\/23744235.2021.1965210 <\/span><\/cite><\/div>\n<div class=\"cit-extra\"><a class=\"cit-ref-sprinkles cit-ref-sprinkles-doi cit-ref-sprinkles-crossref\" href=\"https:\/\/www.medrxiv.org\/lookup\/external-ref?access_num=10.1080\/23744235.2021.1965210&amp;link_type=DOI\">CrossRef <\/a><a class=\"cit-ref-sprinkles cit-ref-sprinkles-google-scholar cit-ref-sprinkles-google-scholar\" href=\"https:\/\/www.medrxiv.org\/lookup\/google-scholar?link_type=googlescholar&amp;gs_type=article&amp;author[0]=A+Lindahl&amp;author[1]=M+Aro&amp;author[2]=J+Reijula&amp;title=Women+report+more+symptoms+and+impaired+quality+of+life:+a+survey+of+Finnish+COVID-19+survivors&amp;publication_year=2022&amp;journal=Infect+Dis&amp;volume=54&amp;pages=53-62\">Google Scholar <\/a><\/div>\n<\/div>\n<\/li>\n<li><span class=\"ref-label\">16. <\/span><a id=\"ref-16\" class=\"rev-xref-ref\" title=\"\u03a0\u03c1\u03bf\u03b2\u03bf\u03bb\u03ae \u03b1\u03bd\u03b1\u03c6\u03bf\u03c1\u03ac\u03c2 16. \u03c3\u03b5 \u03ba\u03b5\u03af\u03bc\u03b5\u03bd\u03bf\" href=\"https:\/\/www.medrxiv.org\/content\/10.1101\/2022.06.14.22276401v1.full#xref-ref-16-1\">\u21b5 <\/a>\n<div id=\"cit-2022.06.14.22276401v1.16\" class=\"cit ref-cit ref-journal google_scholar_link-processed custom-js-processed\" data-doi=\"10.1093\/cid\/ciab611\">\n<div class=\"cit-metadata\"><cite><span class=\"cit-auth\"><span class=\"cit-name-surname\">See\u00dfle <\/span> <span class=\"cit-name-given-names\">J <\/span><\/span>, <span class=\"cit-auth\"><span class=\"cit-name-surname\">Waterboer <\/span> <span class=\"cit-name-given-names\">\u03a4 <\/span><\/span>, <span class=\"cit-auth\"><span class=\"cit-name-surname\">Hippchen <\/span> <span class=\"cit-name-given-names\">\u03a4 <\/span><\/span>, <span class=\"cit-etal\">et al. <\/span> <span class=\"cit-article-title\">\u0395\u03c0\u03af\u03bc\u03bf\u03bd\u03b1 \u03c3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03b1 \u03c3\u03b5 \u03b5\u03bd\u03ae\u03bb\u03b9\u03ba\u03b5\u03c2 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 1 \u03ad\u03c4\u03bf\u03c2 \u03bc\u03b5\u03c4\u03ac \u03c4\u03b7 \u03bd\u03cc\u03c3\u03bf \u03c4\u03bf\u03c5 \u03ba\u03bf\u03c1\u03bf\u03bd\u03b1\u03ca\u03bf\u03cd 2019 (COVID-19): \u039c\u03b9\u03b1 \u03c0\u03c1\u03bf\u03bf\u03c0\u03c4\u03b9\u03ba\u03ae \u03bc\u03b5\u03bb\u03ad\u03c4\u03b7 \u03ba\u03bf\u03cc\u03c1\u03c4\u03b7\u03c2 <\/span>. <abbr class=\"cit-jnl-abbrev\">Clin Infect Dis <\/abbr>. <span class=\"cit-pub-date\">2022 <\/span>; <span class=\"cit-vol\">74 <\/span>( <span class=\"cit-issue\">7 <\/span>): <span class=\"cit-fpage\">1191 <\/span>\u2013 <span class=\"cit-lpage\">1198 <\/span>. <span class=\"cit-pub-id-scheme\">doi: <\/span><span class=\"cit-pub-id cit-pub-id-doi\">10.1093\/cid\/ciab611 <\/span><\/cite><\/div>\n<div class=\"cit-extra\"><a class=\"cit-ref-sprinkles cit-ref-sprinkles-doi cit-ref-sprinkles-crossref\" href=\"https:\/\/www.medrxiv.org\/lookup\/external-ref?access_num=10.1093\/cid\/ciab611&amp;link_type=DOI\">CrossRef <\/a><a class=\"cit-ref-sprinkles cit-ref-sprinkles-google-scholar cit-ref-sprinkles-google-scholar\" href=\"https:\/\/www.medrxiv.org\/lookup\/google-scholar?link_type=googlescholar&amp;gs_type=article&amp;author[0]=J+See\u00dfle&amp;author[1]=T+Waterboer&amp;author[2]=T+Hippchen&amp;title=Persistent+Symptoms+in+Adult+Patients+1+Year+After+Coronavirus+Disease+2019+(COVID-19):+A+Prospective+Cohort+Study&amp;publication_year=2022&amp;journal=Clin+Infect+Dis&amp;volume=74&amp;pages=1191-1198\">Google Scholar <\/a><\/div>\n<\/div>\n<\/li>\n<li><span class=\"ref-label\">17. <\/span><a id=\"ref-17\" class=\"rev-xref-ref\" title=\"\u03a0\u03c1\u03bf\u03b2\u03bf\u03bb\u03ae \u03b1\u03bd\u03b1\u03c6\u03bf\u03c1\u03ac\u03c2 17. \u03c3\u03b5 \u03ba\u03b5\u03af\u03bc\u03b5\u03bd\u03bf\" href=\"https:\/\/www.medrxiv.org\/content\/10.1101\/2022.06.14.22276401v1.full#xref-ref-17-1\">\u21b5 <\/a>\n<div id=\"cit-2022.06.14.22276401v1.17\" class=\"cit ref-cit ref-journal google_scholar_link-processed custom-js-processed\" data-doi=\"10.1038\/nbt.1641\">\n<div class=\"cit-metadata\"><cite><span class=\"cit-auth\"><span class=\"cit-name-surname\">Rissin <\/span> <span class=\"cit-name-given-names\">DM <\/span><\/span>, <span class=\"cit-auth\"><span class=\"cit-name-surname\">Kan <\/span> <span class=\"cit-name-given-names\">CW <\/span><\/span>, <span class=\"cit-auth\"><span class=\"cit-name-surname\">Campbell <\/span> <span class=\"cit-name-given-names\">TG <\/span><\/span>, <span class=\"cit-etal\">et al. <\/span> <span class=\"cit-article-title\">\u0397 \u03bc\u03bf\u03bd\u03bf\u03bc\u03bf\u03c1\u03b9\u03b1\u03ba\u03ae \u03b5\u03bd\u03b6\u03c5\u03bc\u03b9\u03ba\u03ae \u03b1\u03bd\u03bf\u03c3\u03bf\u03c0\u03c1\u03bf\u03c3\u03c1\u03bf\u03c6\u03b7\u03c4\u03b9\u03ba\u03ae \u03b4\u03bf\u03ba\u03b9\u03bc\u03b1\u03c3\u03af\u03b1 \u03b1\u03bd\u03b9\u03c7\u03bd\u03b5\u03cd\u03b5\u03b9 \u03c0\u03c1\u03c9\u03c4\u03b5\u0390\u03bd\u03b5\u03c2 \u03bf\u03c1\u03bf\u03cd \u03c3\u03b5 \u03c5\u03c0\u03bf\u03b8\u03b7\u03c1\u03bf\u03bc\u03bf\u03c1\u03b9\u03b1\u03ba\u03ad\u03c2 \u03c3\u03c5\u03b3\u03ba\u03b5\u03bd\u03c4\u03c1\u03ce\u03c3\u03b5\u03b9\u03c2 <\/span>. <abbr class=\"cit-jnl-abbrev\">Nat Biotechnol <\/abbr>. <span class=\"cit-pub-date\">2010 <\/span>; <span class=\"cit-vol\">28 <\/span>( <span class=\"cit-issue\">6 <\/span>): <span class=\"cit-fpage\">595 <\/span>\u2013 <span class=\"cit-lpage\">599 <\/span>. <span class=\"cit-pub-id-scheme\">doi: <\/span><span class=\"cit-pub-id cit-pub-id-doi\">10.1038\/nbt.1641 <\/span><\/cite><\/div>\n<div class=\"cit-extra\"><a class=\"cit-ref-sprinkles cit-ref-sprinkles-doi cit-ref-sprinkles-crossref\" href=\"https:\/\/www.medrxiv.org\/lookup\/external-ref?access_num=10.1038\/nbt.1641&amp;link_type=DOI\">CrossRef <\/a><a class=\"cit-ref-sprinkles cit-ref-sprinkles-medline\" href=\"https:\/\/www.medrxiv.org\/lookup\/external-ref?access_num=20495550&amp;link_type=MED&amp;atom=%2Fmedrxiv%2Fearly%2F2022%2F06%2F16%2F2022.06.14.22276401.atom\">PubMed <\/a><a class=\"cit-ref-sprinkles cit-ref-sprinkles-newisilink cit-ref-sprinkles-webofscience\" href=\"https:\/\/www.medrxiv.org\/lookup\/external-ref?access_num=000278820200023&amp;link_type=ISI\">Web of Science <\/a><a class=\"cit-ref-sprinkles cit-ref-sprinkles-google-scholar cit-ref-sprinkles-google-scholar\" href=\"https:\/\/www.medrxiv.org\/lookup\/google-scholar?link_type=googlescholar&amp;gs_type=article&amp;author[0]=DM+Rissin&amp;author[1]=CW+Kan&amp;author[2]=TG+Campbell&amp;title=Single-molecule+enzyme-linked+immunosorbent+assay+detects+serum+proteins+at+subfemtomolar+concentrations&amp;publication_year=2010&amp;journal=Nat+Biotechnol&amp;volume=28&amp;pages=595-599\">Google Scholar <\/a><\/div>\n<\/div>\n<\/li>\n<li><span class=\"ref-label\">18. <\/span><a id=\"ref-18\" class=\"rev-xref-ref\" title=\"\u03a0\u03c1\u03bf\u03b2\u03bf\u03bb\u03ae \u03b1\u03bd\u03b1\u03c6\u03bf\u03c1\u03ac\u03c2 18. \u03c3\u03b5 \u03ba\u03b5\u03af\u03bc\u03b5\u03bd\u03bf\" href=\"https:\/\/www.medrxiv.org\/content\/10.1101\/2022.06.14.22276401v1.full#xref-ref-18-1\">\u21b5 <\/a>\n<div id=\"cit-2022.06.14.22276401v1.18\" class=\"cit ref-cit ref-journal google_scholar_link-processed custom-js-processed\" data-doi=\"10.1093\/clinchem\/hvaa213\">\n<div class=\"cit-metadata\"><cite><span class=\"cit-auth\"><span class=\"cit-name-surname\">Ogata <\/span> <span class=\"cit-name-given-names\">AF <\/span><\/span>, <span class=\"cit-auth\"><span class=\"cit-name-surname\">Maley <\/span> <span class=\"cit-name-given-names\">AM <\/span><\/span>, <span class=\"cit-auth\"><span class=\"cit-name-surname\">Wu <\/span> <span class=\"cit-name-given-names\">C <\/span><\/span>, <span class=\"cit-etal\">et al. <\/span> <span class=\"cit-article-title\">\u03a5\u03c0\u03b5\u03c1\u03b5\u03c5\u03b1\u03af\u03c3\u03b8\u03b7\u03c4\u03bf \u03c3\u03b5\u03b9\u03c1\u03b9\u03b1\u03ba\u03cc \u03c0\u03c1\u03bf\u03c6\u03af\u03bb \u03c4\u03c9\u03bd \u03b1\u03bd\u03c4\u03b9\u03b3\u03cc\u03bd\u03c9\u03bd \u03ba\u03b1\u03b9 \u03b1\u03bd\u03c4\u03b9\u03c3\u03c9\u03bc\u03ac\u03c4\u03c9\u03bd SARS-CoV-2 \u03c3\u03c4\u03bf \u03c0\u03bb\u03ac\u03c3\u03bc\u03b1 \u03b3\u03b9\u03b1 \u03c4\u03b7\u03bd \u03ba\u03b1\u03c4\u03b1\u03bd\u03cc\u03b7\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03b5\u03be\u03ad\u03bb\u03b9\u03be\u03b7\u03c2 \u03c4\u03b7\u03c2 \u03bd\u03cc\u03c3\u03bf\u03c5 \u03c3\u03b5 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 \u03c3\u03bf\u03b2\u03b1\u03c1\u03ae \u03bd\u03cc\u03c3\u03bf COVID-19 <\/span>. <abbr class=\"cit-jnl-abbrev\">Clin Chem <\/abbr>. <span class=\"cit-pub-date\">2020 <\/span>; <span class=\"cit-vol\">66 <\/span>( <span class=\"cit-issue\">12 <\/span>): <span class=\"cit-fpage\">1562 <\/span>\u2013 <span class=\"cit-lpage\">1572 <\/span>. <span class=\"cit-pub-id-scheme\">doi: <\/span><span class=\"cit-pub-id cit-pub-id-doi\">10.1093\/clinchem\/hvaa213 <\/span><\/cite><\/div>\n<div class=\"cit-extra\"><a class=\"cit-ref-sprinkles cit-ref-sprinkles-doi cit-ref-sprinkles-crossref\" href=\"https:\/\/www.medrxiv.org\/lookup\/external-ref?access_num=10.1093\/clinchem\/hvaa213&amp;link_type=DOI\">CrossRef <\/a><a class=\"cit-ref-sprinkles cit-ref-sprinkles-google-scholar cit-ref-sprinkles-google-scholar\" href=\"https:\/\/www.medrxiv.org\/lookup\/google-scholar?link_type=googlescholar&amp;gs_type=article&amp;author[0]=AF+Ogata&amp;author[1]=AM+Maley&amp;author[2]=C+Wu&amp;title=Ultra-Sensitive+Serial+Profiling+of+SARS-CoV-2+Antigens+and+Antibodies+in+Plasma+to+Understand+Disease+Progression+in+COVID-19+Patients+with+Severe+Disease&amp;publication_year=2020&amp;journal=Clin+Chem&amp;volume=66&amp;pages=1562-1572\">Google Scholar <\/a><\/div>\n<\/div>\n<\/li>\n<li><span class=\"ref-label\">19. <\/span><a id=\"ref-19\" class=\"rev-xref-ref\" title=\"\u03a0\u03c1\u03bf\u03b2\u03bf\u03bb\u03ae \u03b1\u03bd\u03b1\u03c6\u03bf\u03c1\u03ac\u03c2 19. \u03c3\u03b5 \u03ba\u03b5\u03af\u03bc\u03b5\u03bd\u03bf\" href=\"https:\/\/www.medrxiv.org\/content\/10.1101\/2022.06.14.22276401v1.full#xref-ref-19-1\">\u21b5 <\/a>\n<div id=\"cit-2022.06.14.22276401v1.19\" class=\"cit ref-cit ref-journal google_scholar_link-processed custom-js-processed\" data-doi=\"10.1097\/CCE.0000000000000641\">\n<div class=\"cit-metadata\"><cite><span class=\"cit-auth\"><span class=\"cit-name-surname\">Yonker <\/span> <span class=\"cit-name-given-names\">LM <\/span><\/span>, <span class=\"cit-auth\"><span class=\"cit-name-surname\">Swank <\/span> <span class=\"cit-name-given-names\">Z <\/span><\/span>, <span class=\"cit-auth\"><span class=\"cit-name-surname\">Gilboa <\/span> <span class=\"cit-name-given-names\">\u03a4 <\/span><\/span>, <span class=\"cit-etal\">et al. <\/span> <span class=\"cit-article-title\">\u0391\u03bd\u03c4\u03b1\u03b3\u03c9\u03bd\u03b9\u03c3\u03c4\u03ae\u03c2 Zonulin, Larazotide (AT1001), \u03a9\u03c2 \u03b5\u03c0\u03b9\u03ba\u03bf\u03c5\u03c1\u03b9\u03ba\u03ae \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1 \u03b3\u03b9\u03b1 \u03c0\u03bf\u03bb\u03c5\u03c3\u03c5\u03c3\u03c4\u03b7\u03bc\u03b9\u03ba\u03cc \u03c6\u03bb\u03b5\u03b3\u03bc\u03bf\u03bd\u03ce\u03b4\u03b5\u03c2 \u03c3\u03cd\u03bd\u03b4\u03c1\u03bf\u03bc\u03bf \u03c3\u03b5 \u03c0\u03b1\u03b9\u03b4\u03b9\u03ac: \u03a3\u03b5\u03b9\u03c1\u03ac \u03c0\u03b5\u03c1\u03b9\u03c0\u03c4\u03ce\u03c3\u03b5\u03c9\u03bd <\/span>. <abbr class=\"cit-jnl-abbrev\">Crit Care Explor <\/abbr>. <span class=\"cit-pub-date\">2022 <\/span>; <span class=\"cit-vol\">4 <\/span>( <span class=\"cit-issue\">2 <\/span>): <span class=\"cit-fpage\">e0641 <\/span>. <span class=\"cit-pub-id-scheme\">doi: <\/span><span class=\"cit-pub-id cit-pub-id-doi\">10.1097\/CCE.0000000000000641 <\/span><\/cite><\/div>\n<div class=\"cit-extra\"><a class=\"cit-ref-sprinkles cit-ref-sprinkles-doi cit-ref-sprinkles-crossref\" href=\"https:\/\/www.medrxiv.org\/lookup\/external-ref?access_num=10.1097\/CCE.0000000000000641&amp;link_type=DOI\">CrossRef <\/a><a class=\"cit-ref-sprinkles cit-ref-sprinkles-google-scholar cit-ref-sprinkles-google-scholar\" href=\"https:\/\/www.medrxiv.org\/lookup\/google-scholar?link_type=googlescholar&amp;gs_type=article&amp;author[0]=LM+Yonker&amp;author[1]=Z+Swank&amp;author[2]=T+Gilboa&amp;title=Zonulin+Antagonist,+Larazotide+(AT1001),+As+an+Adjuvant+Treatment+for+Multisystem+Inflammatory+Syndrome+in+Children:+A+Case+Series&amp;publication_year=2022&amp;journal=Crit+Care+Explor&amp;volume=4\">Google Scholar <\/a><\/div>\n<\/div>\n<\/li>\n<li><span class=\"ref-label\">20. <\/span><a id=\"ref-20\" class=\"rev-xref-ref\" title=\"\u03a0\u03c1\u03bf\u03b2\u03bf\u03bb\u03ae \u03b1\u03bd\u03b1\u03c6\u03bf\u03c1\u03ac\u03c2 20. \u03c3\u03b5 \u03ba\u03b5\u03af\u03bc\u03b5\u03bd\u03bf\" href=\"https:\/\/www.medrxiv.org\/content\/10.1101\/2022.06.14.22276401v1.full#xref-ref-20-1\">\u21b5 <\/a>\n<div id=\"cit-2022.06.14.22276401v1.20\" class=\"cit ref-cit ref-journal google_scholar_link-processed custom-js-processed\" data-doi=\"10.1093\/cid\/ciab465\">\n<div class=\"cit-metadata\"><cite><span class=\"cit-auth\"><span class=\"cit-name-surname\">Ogata <\/span> <span class=\"cit-name-given-names\">AF <\/span><\/span>, <span class=\"cit-auth\"><span class=\"cit-name-surname\">Cheng <\/span> <span class=\"cit-name-given-names\">CA <\/span><\/span>, <span class=\"cit-auth\"><span class=\"cit-name-surname\">Desjardins <\/span> <span class=\"cit-name-given-names\">\u039c <\/span><\/span>, <span class=\"cit-etal\">et al. <\/span> <span class=\"cit-article-title\">\u0391\u03bd\u03c4\u03b9\u03b3\u03cc\u03bd\u03bf \u03b5\u03bc\u03b2\u03bf\u03bb\u03af\u03bf\u03c5 \u03ba\u03c5\u03ba\u03bb\u03bf\u03c6\u03bf\u03c1\u03bf\u03cd\u03bd\u03c4\u03bf\u03c2 \u03c3\u03bf\u03b2\u03b1\u03c1\u03bf\u03cd \u03bf\u03be\u03ad\u03bf\u03c2 \u03b1\u03bd\u03b1\u03c0\u03bd\u03b5\u03c5\u03c3\u03c4\u03b9\u03ba\u03bf\u03cd \u03c3\u03c5\u03bd\u03b4\u03c1\u03cc\u03bc\u03bf\u03c5 Coronavirus 2 (SARS-CoV-2) \u0391\u03bd\u03b9\u03c7\u03bd\u03b5\u03cd\u03c4\u03b7\u03ba\u03b5 \u03c3\u03c4\u03bf \u03c0\u03bb\u03ac\u03c3\u03bc\u03b1 \u03c4\u03c9\u03bd \u03bb\u03b7\u03c0\u03c4\u03ce\u03bd \u03b5\u03bc\u03b2\u03bf\u03bb\u03af\u03bf\u03c5 mRNA-1273 <\/span>. <abbr class=\"cit-jnl-abbrev\">Clin Infect Dis <\/abbr>. <span class=\"cit-pub-date\">2021 <\/span>; ( <span class=\"cit-issue\">ciab465 <\/span>). <span class=\"cit-pub-id-scheme\">doi: <\/span><span class=\"cit-pub-id cit-pub-id-doi\">10.1093\/cid\/ciab465 <\/span><\/cite><\/div>\n<div class=\"cit-extra\"><a class=\"cit-ref-sprinkles cit-ref-sprinkles-doi cit-ref-sprinkles-crossref\" href=\"https:\/\/www.medrxiv.org\/lookup\/external-ref?access_num=10.1093\/cid\/ciab465&amp;link_type=DOI\">CrossRef <\/a><a class=\"cit-ref-sprinkles cit-ref-sprinkles-google-scholar cit-ref-sprinkles-google-scholar\" href=\"https:\/\/www.medrxiv.org\/lookup\/google-scholar?link_type=googlescholar&amp;gs_type=article&amp;author[0]=AF+Ogata&amp;author[1]=CA+Cheng&amp;author[2]=M+Desjardins&amp;title=Circulating+Severe+Acute+Respiratory+Syndrome+Coronavirus+2+(SARS-CoV-2)+Vaccine+Antigen+Detected+in+the+Plasma+of+mRNA-1273+Vaccine+Recipients&amp;publication_year=2021&amp;journal=Clin+Infect+Dis\">Google Scholar <\/a><\/div>\n<\/div>\n<\/li>\n<li><span class=\"ref-label\">21. <\/span><a id=\"ref-21\" class=\"rev-xref-ref\" title=\"\u03a0\u03c1\u03bf\u03b2\u03bf\u03bb\u03ae \u03b1\u03bd\u03b1\u03c6\u03bf\u03c1\u03ac\u03c2 21. \u03c3\u03b5 \u03ba\u03b5\u03af\u03bc\u03b5\u03bd\u03bf\" href=\"https:\/\/www.medrxiv.org\/content\/10.1101\/2022.06.14.22276401v1.full#xref-ref-21-1\">\u21b5 <\/a>\n<div id=\"cit-2022.06.14.22276401v1.21\" class=\"cit ref-cit ref-journal google_scholar_link-processed custom-js-processed\" data-doi=\"10.21203\/rs.3.rs-1139035\/v1\">\n<div class=\"cit-metadata\"><cite><span class=\"cit-auth\"><span class=\"cit-name-surname\">Chertow <\/span>, <span class=\"cit-name-given-names\">Daniel <\/span><\/span>, <span class=\"cit-auth\"><span class=\"cit-name-surname\">Stein <\/span>, <span class=\"cit-name-given-names\">Sydney <\/span><\/span>, <span class=\"cit-auth\"><span class=\"cit-name-surname\">Ramelli <\/span>, <span class=\"cit-name-given-names\">Alison <\/span><\/span>, <span class=\"cit-etal\">et al. <\/span> <abbr class=\"cit-jnl-abbrev\">\u039b\u03bf\u03af\u03bc\u03c9\u03be\u03b7 \u03ba\u03b1\u03b9 \u03b5\u03c0\u03b9\u03bc\u03bf\u03bd\u03ae SARS-CoV-2 \u03c3\u03b5 \u03cc\u03bb\u03bf \u03c4\u03bf \u03b1\u03bd\u03b8\u03c1\u03ce\u03c0\u03b9\u03bd\u03bf \u03c3\u03ce\u03bc\u03b1 \u03ba\u03b1\u03b9 \u03c4\u03bf\u03bd \u03b5\u03b3\u03ba\u03ad\u03c6\u03b1\u03bb\u03bf <\/abbr>. \u0394\u03b7\u03bc\u03bf\u03c3\u03b9\u03b5\u03cd\u03b8\u03b7\u03ba\u03b5 \u03b7\u03bb\u03b5\u03ba\u03c4\u03c1\u03bf\u03bd\u03b9\u03ba\u03ac \u03c3\u03c4\u03b9\u03c2 20 \u0394\u03b5\u03ba\u03b5\u03bc\u03b2\u03c1\u03af\u03bf\u03c5 2021. <span class=\"cit-pub-id-scheme\">doi: <\/span><span class=\"cit-pub-id cit-pub-id-doi\">10.21203\/rs.3.rs-1139035\/v1 <\/span><\/cite><\/div>\n<div class=\"cit-extra\"><a class=\"cit-ref-sprinkles cit-ref-sprinkles-doi cit-ref-sprinkles-crossref\" href=\"https:\/\/www.medrxiv.org\/lookup\/external-ref?access_num=10.21203\/rs.3.rs-1139035\/v1&amp;link_type=DOI\">CrossRef <\/a><a class=\"cit-ref-sprinkles cit-ref-sprinkles-google-scholar cit-ref-sprinkles-google-scholar\" href=\"https:\/\/www.medrxiv.org\/lookup\/google-scholar?link_type=googlescholar&amp;gs_type=article&amp;q_txt=Chertow%2C+Daniel%2C+Stein%2C+Sydney%2C+Ramelli%2C+Alison%2C+et+al.+SARS-CoV-2+infection+and+persistence+throughout+the+human+body+and+brain.+Published+online+December+20%2C+2021.+doi%3A10.21203%2Frs.3.rs-1139035%2Fv1\">Google Scholar <\/a><\/div>\n<\/div>\n<\/li>\n<li><span class=\"ref-label\">22. <\/span><a id=\"ref-22\" class=\"rev-xref-ref\" title=\"\u03a0\u03c1\u03bf\u03b2\u03bf\u03bb\u03ae \u03b1\u03bd\u03b1\u03c6\u03bf\u03c1\u03ac\u03c2 22. \u03c3\u03b5 \u03ba\u03b5\u03af\u03bc\u03b5\u03bd\u03bf\" href=\"https:\/\/www.medrxiv.org\/content\/10.1101\/2022.06.14.22276401v1.full#xref-ref-22-1\">\u21b5 <\/a>\n<div id=\"cit-2022.06.14.22276401v1.22\" class=\"cit ref-cit ref-journal google_scholar_link-processed custom-js-processed\" data-doi=\"10.1172\/JCI149633\">\n<div class=\"cit-metadata\"><cite><span class=\"cit-auth\"><span class=\"cit-name-surname\">Yonker <\/span> <span class=\"cit-name-given-names\">LM <\/span><\/span>, <span class=\"cit-auth\"><span class=\"cit-name-surname\">Gilboa <\/span> <span class=\"cit-name-given-names\">T <\/span><\/span>, <span class=\"cit-auth\"><span class=\"cit-name-surname\">Ogata <\/span> <span class=\"cit-name-given-names\">AF <\/span><\/span>, <span class=\"cit-etal\">et al. <\/span> <span class=\"cit-article-title\">\u03a4\u03bf \u03c0\u03bf\u03bb\u03c5\u03c3\u03c5\u03c3\u03c4\u03b7\u03bc\u03b1\u03c4\u03b9\u03ba\u03cc \u03c6\u03bb\u03b5\u03b3\u03bc\u03bf\u03bd\u03ce\u03b4\u03b5\u03c2 \u03c3\u03cd\u03bd\u03b4\u03c1\u03bf\u03bc\u03bf \u03c3\u03c4\u03b1 \u03c0\u03b1\u03b9\u03b4\u03b9\u03ac \u03bf\u03c6\u03b5\u03af\u03bb\u03b5\u03c4\u03b1\u03b9 \u03c3\u03c4\u03b7\u03bd \u03b5\u03be\u03b1\u03c1\u03c4\u03ce\u03bc\u03b5\u03bd\u03b7 \u03b1\u03c0\u03cc \u03c4\u03b7 \u03b6\u03bf\u03bd\u03bf\u03c5\u03bb\u03af\u03bd\u03b7 \u03b1\u03c0\u03ce\u03bb\u03b5\u03b9\u03b1 \u03c4\u03bf\u03c5 \u03c6\u03c1\u03b1\u03b3\u03bc\u03bf\u03cd \u03c4\u03bf\u03c5 \u03b5\u03bd\u03c4\u03b5\u03c1\u03b9\u03ba\u03bf\u03cd \u03b2\u03bb\u03b5\u03bd\u03bd\u03bf\u03b3\u03cc\u03bd\u03bf\u03c5 <\/span>. <abbr class=\"cit-jnl-abbrev\">J Clin Invest <\/abbr>. \u0394\u03b7\u03bc\u03bf\u03c3\u03b9\u03b5\u03cd\u03b8\u03b7\u03ba\u03b5 \u03b7\u03bb\u03b5\u03ba\u03c4\u03c1\u03bf\u03bd\u03b9\u03ba\u03ac \u03c3\u03c4\u03b9\u03c2 25 \u039c\u03b1\u0390\u03bf\u03c5 2021. <span class=\"cit-pub-id-scheme\">doi: <\/span><span class=\"cit-pub-id cit-pub-id-doi\">10.1172\/JCI149633 <\/span><\/cite><\/div>\n<div class=\"cit-extra\"><a class=\"cit-ref-sprinkles cit-ref-sprinkles-doi cit-ref-sprinkles-crossref\" href=\"https:\/\/www.medrxiv.org\/lookup\/external-ref?access_num=10.1172\/JCI149633&amp;link_type=DOI\">CrossRef <\/a><a class=\"cit-ref-sprinkles cit-ref-sprinkles-google-scholar cit-ref-sprinkles-google-scholar\" href=\"https:\/\/www.medrxiv.org\/lookup\/google-scholar?link_type=googlescholar&amp;gs_type=article&amp;q_txt=Yonker+LM%2C+Gilboa+T%2C+Ogata+AF%2C+et+al.+Multisystem+inflammatory+syndrome+in+children+is+driven+by+zonulin-dependent+loss+of+gut+mucosal+barrier.+J+Clin+Invest.+Published+online+May+25%2C+2021.+doi%3A10.1172%2FJCI149633\">Google Scholar <\/a><\/div>\n<\/div>\n<\/li>\n<li><span class=\"ref-label\">23. <\/span><a id=\"ref-23\" class=\"rev-xref-ref\" title=\"\u03a0\u03c1\u03bf\u03b2\u03bf\u03bb\u03ae \u03b1\u03bd\u03b1\u03c6\u03bf\u03c1\u03ac\u03c2 23. \u03c3\u03b5 \u03ba\u03b5\u03af\u03bc\u03b5\u03bd\u03bf\" href=\"https:\/\/www.medrxiv.org\/content\/10.1101\/2022.06.14.22276401v1.full#xref-ref-23-1\">\u21b5 <\/a>\n<div id=\"cit-2022.06.14.22276401v1.23\" class=\"cit ref-cit ref-journal google_scholar_link-processed custom-js-processed\" data-doi=\"10.1136\/gutjnl-2021-325989\">\n<div class=\"cit-metadata\"><cite><span class=\"cit-auth\"><span class=\"cit-name-surname\">Liu <\/span> <span class=\"cit-name-given-names\">Q <\/span><\/span>, <span class=\"cit-auth\"><span class=\"cit-name-surname\">Mak <\/span> <span class=\"cit-name-given-names\">JWY <\/span><\/span>, <span class=\"cit-auth\"><span class=\"cit-name-surname\">Su <\/span> <span class=\"cit-name-given-names\">Q <\/span><\/span>, <span class=\"cit-etal\">et al. <\/span> <span class=\"cit-article-title\">\u0394\u03c5\u03bd\u03b1\u03bc\u03b9\u03ba\u03ae \u03c4\u03b7\u03c2 \u03bc\u03b9\u03ba\u03c1\u03bf\u03c7\u03bb\u03c9\u03c1\u03af\u03b4\u03b1\u03c2 \u03c4\u03bf\u03c5 \u03b5\u03bd\u03c4\u03ad\u03c1\u03bf\u03c5 \u03c3\u03b5 \u03bc\u03b9\u03b1 \u03c0\u03b9\u03b8\u03b1\u03bd\u03ae \u03bf\u03bc\u03ac\u03b4\u03b1 \u03b1\u03c3\u03b8\u03b5\u03bd\u03ce\u03bd \u03bc\u03b5 \u03bc\u03b5\u03c4\u03b1-\u03bf\u03be\u03cd \u03c3\u03cd\u03bd\u03b4\u03c1\u03bf\u03bc\u03bf COVID-19 <\/span>. <abbr class=\"cit-jnl-abbrev\">\u03ad\u03bd\u03c4\u03b5\u03c1\u03bf <\/abbr>. <span class=\"cit-pub-date\">2022 <\/span>; <span class=\"cit-vol\">71 <\/span>( <span class=\"cit-issue\">3 <\/span>): <span class=\"cit-fpage\">544 <\/span>\u2013 <span class=\"cit-lpage\">552 <\/span>. <span class=\"cit-pub-id-scheme\">doi: <\/span><span class=\"cit-pub-id cit-pub-id-doi\">10.1136\/gutjnl-2021-325989 <\/span><\/cite><\/div>\n<div class=\"cit-extra\"><a class=\"cit-ref-sprinkles cit-ref-sprinkles-ijlink\" href=\"https:\/\/www.medrxiv.org\/lookup\/ijlink\/YTozOntzOjQ6InBhdGgiO3M6MTQ6Ii9sb29rdXAvaWpsaW5rIjtzOjU6InF1ZXJ5IjthOjQ6e3M6ODoibGlua1R5cGUiO3M6NDoiQUJTVCI7czoxMToiam91cm5hbENvZGUiO3M6NjoiZ3V0am5sIjtzOjU6InJlc2lkIjtzOjg6IjcxLzMvNTQ0IjtzOjQ6ImF0b20iO3M6NTA6Ii9tZWRyeGl2L2Vhcmx5LzIwMjIvMDYvMTYvMjAyMi4wNi4xNC4yMjI3NjQwMS5hdG9tIjt9czo4OiJmcmFnbWVudCI7czowOiIiO30=\"><span class=\"cit-reflinks-abstract\">Abstract <\/span><span class=\"cit-sep cit-reflinks-variant-name-sep\">\/ <\/span><span class=\"cit-reflinks-full-text\"><span class=\"free-full-text\">\u0394\u03a9\u03a1\u0395\u0391\u039d <\/span>Full Text <\/span><\/a><a class=\"cit-ref-sprinkles cit-ref-sprinkles-google-scholar cit-ref-sprinkles-google-scholar\" href=\"https:\/\/www.medrxiv.org\/lookup\/google-scholar?link_type=googlescholar&amp;gs_type=article&amp;author[0]=Q+Liu&amp;author[1]=JWY+Mak&amp;author[2]=Q+Su&amp;title=Gut+microbiota+dynamics+in+a+prospective+cohort+of+patients+with+post-acute+COVID-19+syndrome&amp;publication_year=2022&amp;journal=Gut&amp;volume=71&amp;pages=544-552\">Google Scholar <\/a><\/div>\n<\/div>\n<\/li>\n<li><span class=\"ref-label\">24. <\/span><a id=\"ref-24\" class=\"rev-xref-ref\" title=\"\u03a0\u03c1\u03bf\u03b2\u03bf\u03bb\u03ae \u03b1\u03bd\u03b1\u03c6\u03bf\u03c1\u03ac\u03c2 24. \u03c3\u03b5 \u03ba\u03b5\u03af\u03bc\u03b5\u03bd\u03bf\" href=\"https:\/\/www.medrxiv.org\/content\/10.1101\/2022.06.14.22276401v1.full#xref-ref-24-1\">\u21b5 <\/a>\n<div id=\"cit-2022.06.14.22276401v1.24\" class=\"cit ref-cit ref-journal google_scholar_link-processed custom-js-processed\" data-doi=\"10.1073\/pnas.2010722117\">\n<div class=\"cit-metadata\"><cite><span class=\"cit-auth\"><span class=\"cit-name-surname\">Cheng <\/span> <span class=\"cit-name-given-names\">MH <\/span><\/span>, <span class=\"cit-auth\"><span class=\"cit-name-surname\">Zhang <\/span> <span class=\"cit-name-given-names\">S <\/span><\/span>, <span class=\"cit-auth\"><span class=\"cit-name-surname\">Porritt <\/span> <span class=\"cit-name-given-names\">RA <\/span><\/span>, <span class=\"cit-etal\">et al. <\/span> <span class=\"cit-article-title\">\u03a5\u03c0\u03b5\u03c1\u03b1\u03bd\u03c4\u03b9\u03b3\u03bf\u03bd\u03b9\u03ba\u03cc\u03c2 \u03c7\u03b1\u03c1\u03b1\u03ba\u03c4\u03ae\u03c1\u03b1\u03c2 \u03b5\u03bd\u03cc\u03c2 \u03ad\u03bd\u03b8\u03b5\u03c4\u03bf\u03c5 \u03bc\u03bf\u03bd\u03b1\u03b4\u03b9\u03ba\u03bf\u03cd \u03b3\u03b9\u03b1 \u03c4\u03b7\u03bd \u03b1\u03ba\u03af\u03b4\u03b1 SARS-CoV-2 \u03c0\u03bf\u03c5 \u03c5\u03c0\u03bf\u03c3\u03c4\u03b7\u03c1\u03af\u03b6\u03b5\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03bb\u03bf\u03be\u03cc \u03c1\u03b5\u03c0\u03b5\u03c1\u03c4\u03cc\u03c1\u03b9\u03bf TCR \u03c3\u03b5 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 \u03c5\u03c0\u03b5\u03c1\u03c6\u03bb\u03b5\u03b3\u03bc\u03bf\u03bd\u03ae <\/span>. <abbr class=\"cit-jnl-abbrev\">Proc Natl Acad Sci <\/abbr>. <span class=\"cit-pub-date\">2020 <\/span>; <span class=\"cit-vol\">117 <\/span>( <span class=\"cit-issue\">41 <\/span>): <span class=\"cit-fpage\">25254 <\/span>\u2013 <span class=\"cit-lpage\">25262 <\/span>. <span class=\"cit-pub-id-scheme\">doi: <\/span><span class=\"cit-pub-id cit-pub-id-doi\">10.1073\/pnas.2010722117 <\/span><\/cite><\/div>\n<div class=\"cit-extra\"><a class=\"cit-ref-sprinkles cit-ref-sprinkles-ijlink\" href=\"https:\/\/www.medrxiv.org\/lookup\/ijlink\/YTozOntzOjQ6InBhdGgiO3M6MTQ6Ii9sb29rdXAvaWpsaW5rIjtzOjU6InF1ZXJ5IjthOjQ6e3M6ODoibGlua1R5cGUiO3M6NDoiQUJTVCI7czoxMToiam91cm5hbENvZGUiO3M6NDoicG5hcyI7czo1OiJyZXNpZCI7czoxMjoiMTE3LzQxLzI1MjU0IjtzOjQ6ImF0b20iO3M6NTA6Ii9tZWRyeGl2L2Vhcmx5LzIwMjIvMDYvMTYvMjAyMi4wNi4xNC4yMjI3NjQwMS5hdG9tIjt9czo4OiJmcmFnbWVudCI7czowOiIiO30=\"><span class=\"cit-reflinks-abstract\">Abstract <\/span><span class=\"cit-sep cit-reflinks-variant-name-sep\">\/ <\/span><span class=\"cit-reflinks-full-text\"><span class=\"free-full-text\">\u0394\u03a9\u03a1\u0395\u0391\u039d <\/span>Full Text <\/span><\/a><a class=\"cit-ref-sprinkles cit-ref-sprinkles-google-scholar cit-ref-sprinkles-google-scholar\" href=\"https:\/\/www.medrxiv.org\/lookup\/google-scholar?link_type=googlescholar&amp;gs_type=article&amp;author[0]=MH+Cheng&amp;author[1]=S+Zhang&amp;author[2]=RA+Porritt&amp;title=Superantigenic+character+of+an+insert+unique+to+SARS-CoV-2+spike+supported+by+skewed+TCR+repertoire+in+patients+with+hyperinflammation&amp;publication_year=2020&amp;journal=Proc+Natl+Acad+Sci&amp;volume=117&amp;pages=25254-25262\">Google Scholar <\/a><\/div>\n<\/div>\n<\/li>\n<li><span class=\"ref-label\">25. <\/span><a id=\"ref-25\" class=\"rev-xref-ref\" title=\"\u03a0\u03c1\u03bf\u03b2\u03bf\u03bb\u03ae \u03b1\u03bd\u03b1\u03c6\u03bf\u03c1\u03ac\u03c2 25. \u03c3\u03b5 \u03ba\u03b5\u03af\u03bc\u03b5\u03bd\u03bf\" href=\"https:\/\/www.medrxiv.org\/content\/10.1101\/2022.06.14.22276401v1.full#xref-ref-25-1\">\u21b5 <\/a>\n<div id=\"cit-2022.06.14.22276401v1.25\" class=\"cit ref-cit ref-journal google_scholar_link-processed custom-js-processed\" data-doi=\"10.1172\/JCI146614\">\n<div class=\"cit-metadata\"><cite><span class=\"cit-auth\"><span class=\"cit-name-surname\">Porritt <\/span> <span class=\"cit-name-given-names\">RA <\/span><\/span>, <span class=\"cit-auth\"><span class=\"cit-name-surname\">Paschold <\/span> <span class=\"cit-name-given-names\">L <\/span><\/span>, <span class=\"cit-auth\"><span class=\"cit-name-surname\">Rivas <\/span> <span class=\"cit-name-given-names\">\u039c\u039d <\/span><\/span>, <span class=\"cit-etal\">et al. <\/span> <span class=\"cit-article-title\">\u0395\u03c0\u03ad\u03ba\u03c4\u03b1\u03c3\u03b7 \u03c3\u03c7\u03b5\u03c4\u03b9\u03b6\u03cc\u03bc\u03b5\u03bd\u03b7 \u03bc\u03b5 HLA \u03ba\u03b1\u03c4\u03b7\u03b3\u03bf\u03c1\u03af\u03b1\u03c2 \u0399 \u03c4\u03c9\u03bd \u03a4 \u03ba\u03c5\u03c4\u03c4\u03ac\u03c1\u03c9\u03bd TRBV11-2 \u03c3\u03c4\u03bf \u03c0\u03bf\u03bb\u03c5\u03c3\u03c5\u03c3\u03c4\u03b7\u03bc\u03b1\u03c4\u03b9\u03ba\u03cc \u03c6\u03bb\u03b5\u03b3\u03bc\u03bf\u03bd\u03ce\u03b4\u03b5\u03c2 \u03c3\u03cd\u03bd\u03b4\u03c1\u03bf\u03bc\u03bf \u03c3\u03b5 \u03c0\u03b1\u03b9\u03b4\u03b9\u03ac <\/span>. <abbr class=\"cit-jnl-abbrev\">J Clin Invest <\/abbr>. <span class=\"cit-pub-date\">2021 <\/span>; <span class=\"cit-vol\">131 <\/span>( <span class=\"cit-issue\">10 <\/span>). <span class=\"cit-pub-id-scheme\">doi: <\/span><span class=\"cit-pub-id cit-pub-id-doi\">10.1172\/JCI146614 <\/span><\/cite><\/div>\n<div class=\"cit-extra\"><a class=\"cit-ref-sprinkles cit-ref-sprinkles-doi cit-ref-sprinkles-crossref\" href=\"https:\/\/www.medrxiv.org\/lookup\/external-ref?access_num=10.1172\/JCI146614&amp;link_type=DOI\">CrossRef <\/a><a class=\"cit-ref-sprinkles cit-ref-sprinkles-medline\" href=\"https:\/\/www.medrxiv.org\/lookup\/external-ref?access_num=33705359&amp;link_type=MED&amp;atom=%2Fmedrxiv%2Fearly%2F2022%2F06%2F16%2F2022.06.14.22276401.atom\">PubMed <\/a><a class=\"cit-ref-sprinkles cit-ref-sprinkles-google-scholar cit-ref-sprinkles-google-scholar\" href=\"https:\/\/www.medrxiv.org\/lookup\/google-scholar?link_type=googlescholar&amp;gs_type=article&amp;author[0]=RA+Porritt&amp;author[1]=L+Paschold&amp;author[2]=MN+Rivas&amp;title=HLA+class+I\u2013associated+expansion+of+TRBV11-2+T+cells+in+multisystem+inflammatory+syndrome+in+children&amp;publication_year=2021&amp;journal=J+Clin+Invest&amp;volume=131\">Google Scholar <\/a><\/div>\n<\/div>\n<\/li>\n<li><span class=\"ref-label\">26. <\/span><a id=\"ref-26\" class=\"rev-xref-ref\" title=\"\u03a0\u03c1\u03bf\u03b2\u03bf\u03bb\u03ae \u03b1\u03bd\u03b1\u03c6\u03bf\u03c1\u03ac\u03c2 26. \u03c3\u03b5 \u03ba\u03b5\u03af\u03bc\u03b5\u03bd\u03bf\" href=\"https:\/\/www.medrxiv.org\/content\/10.1101\/2022.06.14.22276401v1.full#xref-ref-26-1\">\u21b5 <\/a>\n<div id=\"cit-2022.06.14.22276401v1.26\" class=\"cit ref-cit ref-journal google_scholar_link-processed custom-js-processed\" data-doi=\"10.1042\/CS20210735\">\n<div class=\"cit-metadata\"><cite><span class=\"cit-auth\"><span class=\"cit-name-surname\">Avolio <\/span> <span class=\"cit-name-given-names\">\u0395 <\/span><\/span>, <span class=\"cit-auth\"><span class=\"cit-name-surname\">Carrabba <\/span> <span class=\"cit-name-given-names\">\u039c <\/span><\/span>, <span class=\"cit-auth\"><span class=\"cit-name-surname\">Milligan <\/span> <span class=\"cit-name-given-names\">R <\/span><\/span>, <span class=\"cit-etal\">et al. <\/span> <span class=\"cit-article-title\">\u0397 \u03c0\u03c1\u03c9\u03c4\u03b5\u0390\u03bd\u03b7 Spike SARS-CoV-2 \u03b4\u03b9\u03b1\u03c4\u03b1\u03c1\u03ac\u03c3\u03c3\u03b5\u03b9 \u03c4\u03b7 \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03af\u03b1 \u03c4\u03c9\u03bd \u03b1\u03bd\u03b8\u03c1\u03ce\u03c0\u03b9\u03bd\u03c9\u03bd \u03ba\u03b1\u03c1\u03b4\u03b9\u03b1\u03ba\u03ce\u03bd \u03c0\u03b5\u03c1\u03b9\u03ba\u03c5\u03c4\u03c4\u03ac\u03c1\u03c9\u03bd \u03bc\u03ad\u03c3\u03c9 \u03c4\u03b7\u03c2 \u03c3\u03b7\u03bc\u03b1\u03c4\u03bf\u03b4\u03cc\u03c4\u03b7\u03c3\u03b7\u03c2 \u03bc\u03b5 \u03c4\u03b7 \u03bc\u03b5\u03c3\u03bf\u03bb\u03ac\u03b2\u03b7\u03c3\u03b7 \u03c4\u03bf\u03c5 \u03c5\u03c0\u03bf\u03b4\u03bf\u03c7\u03ad\u03b1 CD147: \u03ad\u03bd\u03b1\u03c2 \u03c0\u03b9\u03b8\u03b1\u03bd\u03cc\u03c2 \u03bc\u03b7 \u03bc\u03bf\u03bb\u03c5\u03c3\u03bc\u03b1\u03c4\u03b9\u03ba\u03cc\u03c2 \u03bc\u03b7\u03c7\u03b1\u03bd\u03b9\u03c3\u03bc\u03cc\u03c2 \u03c4\u03b7\u03c2 \u03bc\u03b9\u03ba\u03c1\u03bf\u03b1\u03b3\u03b3\u03b5\u03b9\u03b1\u03ba\u03ae\u03c2 \u03bd\u03cc\u03c3\u03bf\u03c5 COVID-19 <\/span>. <abbr class=\"cit-jnl-abbrev\">Clin Sci <\/abbr>. <span class=\"cit-pub-date\">2021 <\/span>; <span class=\"cit-vol\">135 <\/span>( <span class=\"cit-issue\">24 <\/span>): <span class=\"cit-fpage\">2667 <\/span>\u2013 <span class=\"cit-lpage\">2689 <\/span>. <span class=\"cit-pub-id-scheme\">doi: <\/span><span class=\"cit-pub-id cit-pub-id-doi\">10.1042\/CS20210735 <\/span><\/cite><\/div>\n<div class=\"cit-extra\"><a class=\"cit-ref-sprinkles cit-ref-sprinkles-doi cit-ref-sprinkles-crossref\" href=\"https:\/\/www.medrxiv.org\/lookup\/external-ref?access_num=10.1042\/CS20210735&amp;link_type=DOI\">CrossRef <\/a><a class=\"cit-ref-sprinkles cit-ref-sprinkles-google-scholar cit-ref-sprinkles-google-scholar\" href=\"https:\/\/www.medrxiv.org\/lookup\/google-scholar?link_type=googlescholar&amp;gs_type=article&amp;author[0]=E+Avolio&amp;author[1]=M+Carrabba&amp;author[2]=R+Milligan&amp;title=The+SARS-CoV-2+Spike+protein+disrupts+human+cardiac+pericytes+function+through+CD147+receptor-mediated+signalling:+a+potential+non-infective+mechanism+of+COVID-19+microvascular+disease&amp;publication_year=2021&amp;journal=Clin+Sci&amp;volume=135&amp;pages=2667-2689\">Google Scholar <\/a><\/div>\n<\/div>\n<\/li>\n<li><span class=\"ref-label\">27. <\/span>\n<div id=\"cit-2022.06.14.22276401v1.27\" class=\"cit ref-cit ref-journal no-rev-xref google_scholar_link-processed custom-js-processed\" data-doi=\"10.1016\/j.jbc.2022.101695\">\n<div class=\"cit-metadata\"><cite><span class=\"cit-auth\"><span class=\"cit-name-surname\">Robles <\/span> <span class=\"cit-name-given-names\">JP <\/span><\/span>, <span class=\"cit-auth\"><span class=\"cit-name-surname\">Zamora <\/span> <span class=\"cit-name-given-names\">M <\/span><\/span>, <span class=\"cit-auth\"><span class=\"cit-name-surname\">Adan-Castro <\/span> <span class=\"cit-name-given-names\">E <\/span><\/span>, <span class=\"cit-auth\"><span class=\"cit-name-surname\">Siqueiros-Marquez <\/span> <span class=\"cit-name-given-names\">L <\/span><\/span>, <span class=\"cit-auth\"><span class=\"cit-name-surname\">Martinez de la Escalera <\/span> <span class=\"cit-name-given-names\">G <\/span><\/span>, <span class=\"cit-auth\"><span class=\"cit-name-surname\">Clapp <\/span> <span class=\"cit-name-given-names\">C. <\/span><\/span> <span class=\"cit-article-title\">\u0397 \u03c0\u03c1\u03c9\u03c4\u03b5\u0390\u03bd\u03b7 \u03b1\u03ba\u03af\u03b4\u03b1\u03c2 \u03c4\u03bf\u03c5 SARS-CoV-2 \u03c0\u03c1\u03bf\u03ba\u03b1\u03bb\u03b5\u03af \u03c6\u03bb\u03b5\u03b3\u03bc\u03bf\u03bd\u03ae \u03c4\u03bf\u03c5 \u03b5\u03bd\u03b4\u03bf\u03b8\u03b7\u03bb\u03af\u03bf\u03c5 \u03bc\u03ad\u03c3\u03c9 \u03c4\u03b7\u03c2 \u03c3\u03b7\u03bc\u03b1\u03c4\u03bf\u03b4\u03cc\u03c4\u03b7\u03c3\u03b7\u03c2 \u03b9\u03bd\u03c4\u03b5\u03b3\u03ba\u03c1\u03af\u03bd\u03b7\u03c2 \u03b15\u03b21 \u03ba\u03b1\u03b9 NF-\u03baB <\/span>. <abbr class=\"cit-jnl-abbrev\">J Biol Chem <\/abbr>. <span class=\"cit-pub-date\">2022 <\/span>; <span class=\"cit-vol\">298 <\/span>( <span class=\"cit-issue\">3 <\/span>): <span class=\"cit-fpage\">101695 <\/span>. <span class=\"cit-pub-id-scheme\">doi: <\/span><span class=\"cit-pub-id cit-pub-id-doi\">10.1016\/j.jbc.2022.101695 <\/span><\/cite><\/div>\n<div class=\"cit-extra\"><a class=\"cit-ref-sprinkles cit-ref-sprinkles-doi cit-ref-sprinkles-crossref\" href=\"https:\/\/www.medrxiv.org\/lookup\/external-ref?access_num=10.1016\/j.jbc.2022.101695&amp;link_type=DOI\">CrossRef <\/a><a class=\"cit-ref-sprinkles cit-ref-sprinkles-google-scholar cit-ref-sprinkles-google-scholar\" href=\"https:\/\/www.medrxiv.org\/lookup\/google-scholar?link_type=googlescholar&amp;gs_type=article&amp;author[0]=JP+Robles&amp;author[1]=M+Zamora&amp;author[2]=E+Adan-Castro&amp;author[3]=L+Siqueiros-Marquez&amp;author[4]=G+Martinez de la Escalera&amp;author[5]=C.+Clapp&amp;title=The+spike+protein+of+SARS-CoV-2+induces+endothelial+inflammation+through+integrin+\u03b15\u03b21+and+NF-\u03baB+signaling&amp;publication_year=2022&amp;journal=J+Biol+Chem&amp;volume=298\">Google Scholar <\/a><\/div>\n<\/div>\n<\/li>\n<li><span class=\"ref-label\">28. <\/span>\n<div id=\"cit-2022.06.14.22276401v1.28\" class=\"cit ref-cit ref-journal no-rev-xref google_scholar_link-processed custom-js-processed\" data-doi=\"10.1161\/CIRCRESAHA.121.318902\">\n<div class=\"cit-metadata\"><cite><span class=\"cit-auth\"><span class=\"cit-name-surname\">Lei <\/span> <span class=\"cit-name-given-names\">Y <\/span><\/span>, <span class=\"cit-auth\"><span class=\"cit-name-surname\">Zhang <\/span> <span class=\"cit-name-given-names\">J <\/span><\/span>, <span class=\"cit-auth\"><span class=\"cit-name-surname\">Schiavon <\/span> <span class=\"cit-name-given-names\">CR <\/span><\/span>, <span class=\"cit-etal\">et al. <\/span> <span class=\"cit-article-title\">\u0397 \u03c0\u03c1\u03c9\u03c4\u03b5\u0390\u03bd\u03b7 Spike SARS-CoV-2 \u03b2\u03bb\u03ac\u03c0\u03c4\u03b5\u03b9 \u03c4\u03b7\u03bd \u03b5\u03bd\u03b4\u03bf\u03b8\u03b7\u03bb\u03b9\u03b1\u03ba\u03ae \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03af\u03b1 \u03bc\u03ad\u03c3\u03c9 \u03c4\u03b7\u03c2 \u03bc\u03b5\u03af\u03c9\u03c3\u03b7\u03c2 \u03c4\u03bf\u03c5 ACE 2 <\/span>. <abbr class=\"cit-jnl-abbrev\">Circ Res <\/abbr>. <span class=\"cit-pub-date\">2021 <\/span>; <span class=\"cit-vol\">128 <\/span>( <span class=\"cit-issue\">9 <\/span>): <span class=\"cit-fpage\">1323 <\/span>\u2013 <span class=\"cit-lpage\">1326 <\/span>. <span class=\"cit-pub-id-scheme\">doi: <\/span><span class=\"cit-pub-id cit-pub-id-doi\">10.1161\/CIRCRESAHA.121.318902 <\/span><\/cite><\/div>\n<div class=\"cit-extra\"><a class=\"cit-ref-sprinkles cit-ref-sprinkles-doi cit-ref-sprinkles-crossref\" href=\"https:\/\/www.medrxiv.org\/lookup\/external-ref?access_num=10.1161\/CIRCRESAHA.121.318902&amp;link_type=DOI\">CrossRef <\/a><a class=\"cit-ref-sprinkles cit-ref-sprinkles-google-scholar cit-ref-sprinkles-google-scholar\" href=\"https:\/\/www.medrxiv.org\/lookup\/google-scholar?link_type=googlescholar&amp;gs_type=article&amp;author[0]=Y+Lei&amp;author[1]=J+Zhang&amp;author[2]=CR+Schiavon&amp;title=SARS-CoV-2+Spike+Protein+Impairs+Endothelial+Function+via+Downregulation+of+ACE+2&amp;publication_year=2021&amp;journal=Circ+Res&amp;volume=128&amp;pages=1323-1326\">Google Scholar <\/a><\/div>\n<\/div>\n<\/li>\n<li><span class=\"ref-label\">29. <\/span><a id=\"ref-29\" class=\"rev-xref-ref\" title=\"\u03a0\u03c1\u03bf\u03b2\u03bf\u03bb\u03ae \u03b1\u03bd\u03b1\u03c6\u03bf\u03c1\u03ac\u03c2 29. \u03c3\u03b5 \u03ba\u03b5\u03af\u03bc\u03b5\u03bd\u03bf\" href=\"https:\/\/www.medrxiv.org\/content\/10.1101\/2022.06.14.22276401v1.full#xref-ref-29-1\">\u21b5 <\/a>\n<div id=\"cit-2022.06.14.22276401v1.29\" class=\"cit ref-cit ref-journal google_scholar_link-processed custom-js-processed\" data-doi=\"10.1007\/s11481-021-10029-0\">\n<div class=\"cit-metadata\"><cite><span class=\"cit-auth\"><span class=\"cit-name-surname\">DeOre <\/span> <span class=\"cit-name-given-names\">BJ <\/span><\/span>, <span class=\"cit-auth\"><span class=\"cit-name-surname\">Tran <\/span> <span class=\"cit-name-given-names\">KA <\/span><\/span>, <span class=\"cit-auth\"><span class=\"cit-name-surname\">Andrews <\/span> <span class=\"cit-name-given-names\">AM <\/span><\/span>, <span class=\"cit-auth\"><span class=\"cit-name-surname\">Ramirez <\/span> <span class=\"cit-name-given-names\">SH <\/span><\/span>, <span class=\"cit-auth\"><span class=\"cit-name-surname\">Galie <\/span> <span class=\"cit-name-given-names\">PA <\/span><\/span>. <span class=\"cit-article-title\">\u0397 \u03c0\u03c1\u03c9\u03c4\u03b5\u0390\u03bd\u03b7 Spike SARS-CoV-2 \u03b4\u03b9\u03b1\u03c4\u03b1\u03c1\u03ac\u03c3\u03c3\u03b5\u03b9 \u03c4\u03b7\u03bd \u03b1\u03ba\u03b5\u03c1\u03b1\u03b9\u03cc\u03c4\u03b7\u03c4\u03b1 \u03c4\u03bf\u03c5 \u03b1\u03b9\u03bc\u03b1\u03c4\u03bf\u03b5\u03b3\u03ba\u03b5\u03c6\u03b1\u03bb\u03b9\u03ba\u03bf\u03cd \u03c6\u03c1\u03b1\u03b3\u03bc\u03bf\u03cd \u03bc\u03ad\u03c3\u03c9 \u03c4\u03b7\u03c2 \u03b5\u03bd\u03b5\u03c1\u03b3\u03bf\u03c0\u03bf\u03af\u03b7\u03c3\u03b7\u03c2 RhoA <\/span>. <abbr class=\"cit-jnl-abbrev\">J Neuroimmune Pharmacol <\/abbr>. <span class=\"cit-pub-date\">2021 <\/span>; <span class=\"cit-vol\">16 <\/span>( <span class=\"cit-issue\">4 <\/span>): <span class=\"cit-fpage\">722 <\/span>\u2013 <span class=\"cit-lpage\">728 <\/span>. <span class=\"cit-pub-id-scheme\">doi: <\/span><span class=\"cit-pub-id cit-pub-id-doi\">10.1007\/s11481-021-10029-0 <\/span><\/cite><\/div>\n<div class=\"cit-extra\"><a class=\"cit-ref-sprinkles cit-ref-sprinkles-doi cit-ref-sprinkles-crossref\" href=\"https:\/\/www.medrxiv.org\/lookup\/external-ref?access_num=10.1007\/s11481-021-10029-0&amp;link_type=DOI\">CrossRef <\/a><a class=\"cit-ref-sprinkles cit-ref-sprinkles-google-scholar cit-ref-sprinkles-google-scholar\" href=\"https:\/\/www.medrxiv.org\/lookup\/google-scholar?link_type=googlescholar&amp;gs_type=article&amp;author[0]=BJ+DeOre&amp;author[1]=KA+Tran&amp;author[2]=AM+Andrews&amp;author[3]=SH+Ramirez&amp;author[4]=PA+Galie&amp;title=SARS-CoV-2+Spike+Protein+Disrupts+Blood\u2013Brain+Barrier+Integrity+via+RhoA+Activation&amp;publication_year=2021&amp;journal=J+Neuroimmune+Pharmacol&amp;volume=16&amp;pages=722-728\">Google Scholar <\/a><\/div>\n<\/div>\n<\/li>\n<li><span class=\"ref-label\">30. <\/span><a id=\"ref-30\" class=\"rev-xref-ref\" title=\"\u03a0\u03c1\u03bf\u03b2\u03bf\u03bb\u03ae \u03b1\u03bd\u03b1\u03c6\u03bf\u03c1\u03ac\u03c2 30. \u03c3\u03b5 \u03ba\u03b5\u03af\u03bc\u03b5\u03bd\u03bf\" href=\"https:\/\/www.medrxiv.org\/content\/10.1101\/2022.06.14.22276401v1.full#xref-ref-30-1\">\u21b5 <\/a>\n<div id=\"cit-2022.06.14.22276401v1.30\" class=\"cit ref-cit ref-journal google_scholar_link-processed custom-js-processed\" data-doi=\"10.1093\/infdis\/jiab490\">\n<div class=\"cit-metadata\"><cite><span class=\"cit-auth\"><span class=\"cit-name-surname\">Peluso <\/span> <span class=\"cit-name-given-names\">MJ <\/span><\/span>, <span class=\"cit-auth\"><span class=\"cit-name-surname\">Lu <\/span> <span class=\"cit-name-given-names\">S <\/span><\/span>, <span class=\"cit-auth\"><span class=\"cit-name-surname\">Tang <\/span> <span class=\"cit-name-given-names\">AF <\/span><\/span>, <span class=\"cit-etal\">et al. <\/span> <span class=\"cit-article-title\">\u0394\u03b5\u03af\u03ba\u03c4\u03b5\u03c2 \u03b1\u03bd\u03bf\u03c3\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ae\u03c2 \u03b5\u03bd\u03b5\u03c1\u03b3\u03bf\u03c0\u03bf\u03af\u03b7\u03c3\u03b7\u03c2 \u03ba\u03b1\u03b9 \u03c6\u03bb\u03b5\u03b3\u03bc\u03bf\u03bd\u03ae\u03c2 \u03c3\u03b5 \u03ac\u03c4\u03bf\u03bc\u03b1 \u03bc\u03b5 \u03bc\u03b5\u03c4\u03b1\u03b3\u03b5\u03bd\u03ad\u03c3\u03c4\u03b5\u03c1\u03b1 \u03b5\u03c0\u03b1\u03ba\u03cc\u03bb\u03bf\u03c5\u03b8\u03b1 \u03b1\u03c0\u03cc \u03bb\u03bf\u03af\u03bc\u03c9\u03be\u03b7 \u03b1\u03c0\u03cc \u03ba\u03bf\u03c1\u03c9\u03bd\u03bf\u03ca\u03cc 2 \u03bc\u03b5 \u03c3\u03bf\u03b2\u03b1\u03c1\u03cc \u03bf\u03be\u03cd \u03b1\u03bd\u03b1\u03c0\u03bd\u03b5\u03c5\u03c3\u03c4\u03b9\u03ba\u03cc \u03c3\u03cd\u03bd\u03b4\u03c1\u03bf\u03bc\u03bf <\/span>. <abbr class=\"cit-jnl-abbrev\">J Infect Dis <\/abbr>. <span class=\"cit-pub-date\">2021 <\/span>; <span class=\"cit-vol\">224 <\/span>( <span class=\"cit-issue\">11 <\/span>): <span class=\"cit-fpage\">1839 <\/span>\u2013 <span class=\"cit-lpage\">1848 <\/span>. <span class=\"cit-pub-id-scheme\">doi: <\/span><span class=\"cit-pub-id cit-pub-id-doi\">10.1093\/infdis\/jiab490 <\/span><\/cite><\/div>\n<div class=\"cit-extra\"><a class=\"cit-ref-sprinkles cit-ref-sprinkles-doi cit-ref-sprinkles-crossref\" href=\"https:\/\/www.medrxiv.org\/lookup\/external-ref?access_num=10.1093\/infdis\/jiab490&amp;link_type=DOI\">CrossRef <\/a><a class=\"cit-ref-sprinkles cit-ref-sprinkles-google-scholar cit-ref-sprinkles-google-scholar\" href=\"https:\/\/www.medrxiv.org\/lookup\/google-scholar?link_type=googlescholar&amp;gs_type=article&amp;author[0]=MJ+Peluso&amp;author[1]=S+Lu&amp;author[2]=AF+Tang&amp;title=Markers+of+Immune+Activation+and+Inflammation+in+Individuals+With+Postacute+Sequelae+of+Severe+Acute+Respiratory+Syndrome+Coronavirus+2+Infection&amp;publication_year=2021&amp;journal=J+Infect+Dis&amp;volume=224&amp;pages=1839-1848\">Google Scholar <\/a><\/div>\n<\/div>\n<\/li>\n<li><span class=\"ref-label\">31. <\/span><a id=\"ref-31\" class=\"rev-xref-ref\" title=\"\u03a0\u03c1\u03bf\u03b2\u03bf\u03bb\u03ae \u03b1\u03bd\u03b1\u03c6\u03bf\u03c1\u03ac\u03c2 31. \u03c3\u03b5 \u03ba\u03b5\u03af\u03bc\u03b5\u03bd\u03bf\" href=\"https:\/\/www.medrxiv.org\/content\/10.1101\/2022.06.14.22276401v1.full#xref-ref-31-1\">\u21b5 <\/a>\n<div id=\"cit-2022.06.14.22276401v1.31\" class=\"cit ref-cit ref-journal google_scholar_link-processed custom-js-processed\" data-doi=\"10.1016\/j.mayocp.2022.01.020\">\n<div class=\"cit-metadata\"><cite><span class=\"cit-auth\"><span class=\"cit-name-surname\">Durstenfeld <\/span> <span class=\"cit-name-given-names\">MS <\/span><\/span>, <span class=\"cit-auth\"><span class=\"cit-name-surname\">Hsue <\/span> <span class=\"cit-name-given-names\">PY <\/span><\/span>, <span class=\"cit-auth\"><span class=\"cit-name-surname\">Peluso <\/span> <span class=\"cit-name-given-names\">MJ <\/span><\/span>, <span class=\"cit-auth\"><span class=\"cit-name-surname\">Deeks <\/span> <span class=\"cit-name-given-names\">SG <\/span><\/span>. <span class=\"cit-article-title\">\u0395\u03c5\u03c1\u03ae\u03bc\u03b1\u03c4\u03b1 \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03bc\u03b5\u03c4\u03ac \u03c4\u03b7\u03bd COVID-19 \u03c4\u03b7\u03c2 Mayo Clinic: \u039f\u03b9 \u03c6\u03b1\u03b9\u03bd\u03cc\u03c4\u03c5\u03c0\u03bf\u03b9 PASC \u03c0\u03bf\u03b9\u03ba\u03af\u03bb\u03bb\u03bf\u03c5\u03bd \u03b1\u03bd\u03ac \u03c6\u03cd\u03bb\u03bf \u03ba\u03b1\u03b9 \u03b2\u03b1\u03b8\u03bc\u03cc \u03b1\u03bd\u03cd\u03c8\u03c9\u03c3\u03b7\u03c2 \u03c4\u03b7\u03c2 IL-6 <\/span>. <abbr class=\"cit-jnl-abbrev\">Mayo Clin Proc <\/abbr>. <span class=\"cit-pub-date\">2022 <\/span>; <span class=\"cit-vol\">97 <\/span>( <span class=\"cit-issue\">3 <\/span>): <span class=\"cit-fpage\">430 <\/span>\u2013 <span class=\"cit-lpage\">432 <\/span>. <span class=\"cit-pub-id-scheme\">doi: <\/span><span class=\"cit-pub-id cit-pub-id-doi\">10.1016\/j.mayocp.2022.01.020 <\/span><\/cite><\/div>\n<div class=\"cit-extra\"><a class=\"cit-ref-sprinkles cit-ref-sprinkles-doi cit-ref-sprinkles-crossref\" href=\"https:\/\/www.medrxiv.org\/lookup\/external-ref?access_num=10.1016\/j.mayocp.2022.01.020&amp;link_type=DOI\">CrossRef <\/a><a class=\"cit-ref-sprinkles cit-ref-sprinkles-google-scholar cit-ref-sprinkles-google-scholar\" href=\"https:\/\/www.medrxiv.org\/lookup\/google-scholar?link_type=googlescholar&amp;gs_type=article&amp;author[0]=MS+Durstenfeld&amp;author[1]=PY+Hsue&amp;author[2]=MJ+Peluso&amp;author[3]=SG+Deeks&amp;title=Findings+From+Mayo+Clinic\u2019s+Post-COVID+Clinic:+PASC+Phenotypes+Vary+by+Sex+and+Degree+of+IL-6+Elevation&amp;publication_year=2022&amp;journal=Mayo+Clin+Proc&amp;volume=97&amp;pages=430-432\">Google Scholar <\/a><\/div>\n<\/div>\n<\/li>\n<li><span class=\"ref-label\">32. <\/span><a id=\"ref-32\" class=\"rev-xref-ref\" title=\"\u0394\u03b5\u03af\u03c4\u03b5 \u03c4\u03b7\u03bd \u03b1\u03bd\u03b1\u03c6\u03bf\u03c1\u03ac 32. \u03c3\u03b5 \u03ba\u03b5\u03af\u03bc\u03b5\u03bd\u03bf\" href=\"https:\/\/www.medrxiv.org\/content\/10.1101\/2022.06.14.22276401v1.full#xref-ref-32-1\">\u21b5 <\/a>\n<div id=\"cit-2022.06.14.22276401v1.32\" class=\"cit ref-cit ref-journal google_scholar_link-processed custom-js-processed\" data-doi=\"10.1038\/s41590-021-01113-x\">\n<div class=\"cit-metadata\"><cite><span class=\"cit-auth\"><span class=\"cit-name-surname\">Phetsouphanh <\/span> <span class=\"cit-name-given-names\">C <\/span><\/span>, <span class=\"cit-auth\"><span class=\"cit-name-surname\">Darley <\/span> <span class=\"cit-name-given-names\">DR <\/span><\/span>, <span class=\"cit-auth\"><span class=\"cit-name-surname\">Wilson <\/span> <span class=\"cit-name-given-names\">DB <\/span><\/span>, <span class=\"cit-etal\">et al. <\/span> <span class=\"cit-article-title\">\u0397 \u03b1\u03bd\u03bf\u03c3\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ae \u03b4\u03c5\u03c3\u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03af\u03b1 \u03b5\u03c0\u03b9\u03bc\u03ad\u03bd\u03b5\u03b9 \u03b3\u03b9\u03b1 8 \u03bc\u03ae\u03bd\u03b5\u03c2 \u03bc\u03b5\u03c4\u03ac \u03c4\u03b7\u03bd \u03b1\u03c1\u03c7\u03b9\u03ba\u03ae \u03ae\u03c0\u03b9\u03b1 \u03ad\u03c9\u03c2 \u03bc\u03ad\u03c4\u03c1\u03b9\u03b1 \u03bb\u03bf\u03af\u03bc\u03c9\u03be\u03b7 SARS-CoV-2 <\/span>. <abbr class=\"cit-jnl-abbrev\">Nat Immunol <\/abbr>. <span class=\"cit-pub-date\">2022 <\/span>; <span class=\"cit-vol\">23 <\/span>( <span class=\"cit-issue\">2 <\/span>): <span class=\"cit-fpage\">210 <\/span>\u2013 <span class=\"cit-lpage\">216 <\/span>. <span class=\"cit-pub-id-scheme\">doi: <\/span><span class=\"cit-pub-id cit-pub-id-doi\">10.1038\/s41590-021-01113-x <\/span><\/cite><\/div>\n<div class=\"cit-extra\"><a class=\"cit-ref-sprinkles cit-ref-sprinkles-doi cit-ref-sprinkles-crossref\" href=\"https:\/\/www.medrxiv.org\/lookup\/external-ref?access_num=10.1038\/s41590-021-01113-x&amp;link_type=DOI\">CrossRef <\/a><a class=\"cit-ref-sprinkles cit-ref-sprinkles-medline\" href=\"https:\/\/www.medrxiv.org\/lookup\/external-ref?access_num=35027728&amp;link_type=MED&amp;atom=%2Fmedrxiv%2Fearly%2F2022%2F06%2F16%2F2022.06.14.22276401.atom\">PubMed <\/a><a class=\"cit-ref-sprinkles cit-ref-sprinkles-google-scholar cit-ref-sprinkles-google-scholar\" href=\"https:\/\/www.medrxiv.org\/lookup\/google-scholar?link_type=googlescholar&amp;gs_type=article&amp;author[0]=C+Phetsouphanh&amp;author[1]=DR+Darley&amp;author[2]=DB+Wilson&amp;title=Immunological+dysfunction+persists+for+8+months+following+initial+mild-to-moderate+SARS-CoV-2+infection&amp;publication_year=2022&amp;journal=Nat+Immunol&amp;volume=23&amp;pages=210-216\">Google Scholar <\/a><\/div>\n<\/div>\n<\/li>\n<li><span class=\"ref-label\">33. <\/span><a id=\"ref-33\" class=\"rev-xref-ref\" title=\"\u0394\u03b5\u03af\u03c4\u03b5 \u03c4\u03b7\u03bd \u03b1\u03bd\u03b1\u03c6\u03bf\u03c1\u03ac 33. \u03c3\u03b5 \u03ba\u03b5\u03af\u03bc\u03b5\u03bd\u03bf\" href=\"https:\/\/www.medrxiv.org\/content\/10.1101\/2022.06.14.22276401v1.full#xref-ref-33-1\">\u21b5 <\/a>\n<div id=\"cit-2022.06.14.22276401v1.33\" class=\"cit ref-cit ref-journal google_scholar_link-processed custom-js-processed\" data-doi=\"10.1038\/s41467-021-27797-1\">\n<div class=\"cit-metadata\"><cite><span class=\"cit-auth\"><span class=\"cit-name-surname\">Cervia <\/span> <span class=\"cit-name-given-names\">C <\/span><\/span>, <span class=\"cit-auth\"><span class=\"cit-name-surname\">Zurbuchen <\/span> <span class=\"cit-name-given-names\">\u03a5 <\/span><\/span>, <span class=\"cit-auth\"><span class=\"cit-name-surname\">Taeschler <\/span> <span class=\"cit-name-given-names\">\u03a1 <\/span><\/span>, <span class=\"cit-etal\">et \u03b1\u03ca. <\/span> <span class=\"cit-article-title\">\u0397 \u03c5\u03c0\u03bf\u03b3\u03c1\u03b1\u03c6\u03ae \u03b1\u03bd\u03bf\u03c3\u03bf\u03c3\u03c6\u03b1\u03b9\u03c1\u03af\u03bd\u03b7\u03c2 \u03c0\u03c1\u03bf\u03b2\u03bb\u03ad\u03c0\u03b5\u03b9 \u03c4\u03bf\u03bd \u03ba\u03af\u03bd\u03b4\u03c5\u03bd\u03bf \u03bc\u03b5\u03c4\u03b1-\u03bf\u03be\u03b5\u03af\u03b1\u03c2 \u03c3\u03c5\u03bd\u03b4\u03c1\u03cc\u03bc\u03bf\u03c5 COVID-19 <\/span>. <abbr class=\"cit-jnl-abbrev\">Nat Commun <\/abbr>. <span class=\"cit-pub-date\">2022 <\/span>; <span class=\"cit-vol\">13 <\/span>( <span class=\"cit-issue\">1 <\/span>): <span class=\"cit-fpage\">446 <\/span>. <span class=\"cit-pub-id-scheme\">doi: <\/span><span class=\"cit-pub-id cit-pub-id-doi\">10.1038\/s41467-021-27797-1 <\/span><\/cite><\/div>\n<div class=\"cit-extra\"><a class=\"cit-ref-sprinkles cit-ref-sprinkles-doi cit-ref-sprinkles-crossref\" href=\"https:\/\/www.medrxiv.org\/lookup\/external-ref?access_num=10.1038\/s41467-021-27797-1&amp;link_type=DOI\">CrossRef <\/a><a class=\"cit-ref-sprinkles cit-ref-sprinkles-medline\" href=\"https:\/\/www.medrxiv.org\/lookup\/external-ref?access_num=35078982&amp;link_type=MED&amp;atom=%2Fmedrxiv%2Fearly%2F2022%2F06%2F16%2F2022.06.14.22276401.atom\">PubMed <\/a><a class=\"cit-ref-sprinkles cit-ref-sprinkles-google-scholar cit-ref-sprinkles-google-scholar\" href=\"https:\/\/www.medrxiv.org\/lookup\/google-scholar?link_type=googlescholar&amp;gs_type=article&amp;author[0]=C+Cervia&amp;author[1]=Y+Zurbuchen&amp;author[2]=P+Taeschler&amp;title=Immunoglobulin+signature+predicts+risk+of+post-acute+COVID-19+syndrome&amp;publication_year=2022&amp;journal=Nat+Commun&amp;volume=13\">Google Scholar <\/a><\/div>\n<\/div>\n<\/li>\n<li><span class=\"ref-label\">34. <\/span><a id=\"ref-34\" class=\"rev-xref-ref\" title=\"\u03a0\u03c1\u03bf\u03b2\u03bf\u03bb\u03ae \u03b1\u03bd\u03b1\u03c6\u03bf\u03c1\u03ac\u03c2 34. \u03c3\u03b5 \u03ba\u03b5\u03af\u03bc\u03b5\u03bd\u03bf\" href=\"https:\/\/www.medrxiv.org\/content\/10.1101\/2022.06.14.22276401v1.full#xref-ref-34-1\">\u21b5 <\/a>\n<div id=\"cit-2022.06.14.22276401v1.34\" class=\"cit ref-cit ref-journal google_scholar_link-processed custom-js-processed\" data-doi=\"10.1016\/j.cell.2022.01.014\">\n<div class=\"cit-metadata\"><cite><span class=\"cit-auth\"><span class=\"cit-name-surname\">Su <\/span> <span class=\"cit-name-given-names\">Y <\/span><\/span>, <span class=\"cit-auth\"><span class=\"cit-name-surname\">Yuan <\/span> <span class=\"cit-name-given-names\">D <\/span><\/span>, <span class=\"cit-auth\"><span class=\"cit-name-surname\">Chen <\/span> <span class=\"cit-name-given-names\">DG <\/span><\/span>, <span class=\"cit-etal\">et al. <\/span> <span class=\"cit-article-title\">\u03a0\u03bf\u03bb\u03bb\u03bf\u03af \u03c0\u03c1\u03ce\u03b9\u03bc\u03bf\u03b9 \u03c0\u03b1\u03c1\u03ac\u03b3\u03bf\u03bd\u03c4\u03b5\u03c2 \u03c0\u03c1\u03bf\u03b2\u03bb\u03ad\u03c0\u03bf\u03c5\u03bd \u03bc\u03b5\u03c4\u03b1-\u03bf\u03be\u03b5\u03af\u03b1 \u03b5\u03c0\u03b1\u03ba\u03cc\u03bb\u03bf\u03c5\u03b8\u03b1 \u03c4\u03bf\u03c5 COVID-19 <\/span>. <abbr class=\"cit-jnl-abbrev\">\u039a\u03cd\u03c4\u03c4\u03b1\u03c1\u03bf <\/abbr>. <span class=\"cit-pub-date\">2022 <\/span>; <span class=\"cit-vol\">185 <\/span>( <span class=\"cit-issue\">5 <\/span>): <span class=\"cit-fpage\">881 <\/span>\u2013 <span class=\"cit-lpage\">895 <\/span>.e20. <span class=\"cit-pub-id-scheme\">doi: <\/span><span class=\"cit-pub-id cit-pub-id-doi\">10.1016\/j.cell.2022.01.014 <\/span><\/cite><\/div>\n<div class=\"cit-extra\"><a class=\"cit-ref-sprinkles cit-ref-sprinkles-doi cit-ref-sprinkles-crossref\" href=\"https:\/\/www.medrxiv.org\/lookup\/external-ref?access_num=10.1016\/j.cell.2022.01.014&amp;link_type=DOI\">CrossRef <\/a><a class=\"cit-ref-sprinkles cit-ref-sprinkles-google-scholar cit-ref-sprinkles-google-scholar\" href=\"https:\/\/www.medrxiv.org\/lookup\/google-scholar?link_type=googlescholar&amp;gs_type=article&amp;author[0]=Y+Su&amp;author[1]=D+Yuan&amp;author[2]=DG+Chen&amp;title=Multiple+early+factors+anticipate+post-acute+COVID-19+sequelae&amp;publication_year=2022&amp;journal=Cell&amp;volume=185&amp;pages=881-895\">Google Scholar <\/a><\/div>\n<\/div>\n<\/li>\n<\/ol>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"panel-separator\"><\/div>\n<div class=\"panel-pane pane-highwire-back-to-top\"><\/div>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"sidebar-right-wrapper grid-10 omega\">\n<div class=\"panel-panel panel-region-sidebar-right\">\n<div class=\"inside\">\n<div class=\"panel-pane pane-custom pane-1\">\n<div class=\"pane-content\">\u0394\u03b7\u03bc\u03bf\u03c3\u03b9\u03b5\u03cd\u03c4\u03b7\u03ba\u03b5 \u03c3\u03c4\u03b9\u03c2 16 \u0399\u03bf\u03c5\u03bd\u03af\u03bf\u03c5 2022.<\/div>\n<\/div>\n<div class=\"panel-separator\"><\/div>\n<div class=\"panel-pane pane-panels-mini pane-biorxiv-art-tools\">\n<div class=\"pane-content\">\n<div id=\"mini-panel-biorxiv_art_tools\" class=\"highwire-2col-stacked panel-display\">\n<div class=\"panel-row-wrapper clearfix\">\n<div class=\"content-left-wrapper content-column\">\n<div class=\"panel-panel panel-region-content-left\">\n<div class=\"inside\">\n<div class=\"panel-pane pane-highwire-variant-link\">\u03a0\u0397\u0393\u0397:https:\/\/www.medrxiv.org\/content\/10.1101\/2022.06.14.22276401v1.full \u03ba\u03b1\u03b9 \u0392\u039dJ.<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"panel-pane pane-panels-mini pane-biorxiv-subject-collections block-style-col2\">\n<div class=\"pane-content\">\n<div id=\"czilogo\" class=\"panel-pane pane-czi-link\"><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>\u0397 \u03b5\u03c0\u03af\u03bc\u03bf\u03bd\u03b7 \u03ba\u03c5\u03ba\u03bb\u03bf\u03c6\u03bf\u03c1\u03bf\u03cd\u03c3\u03b1 \u03b1\u03ba\u03af\u03b4\u03b1 SARS-CoV-2 \u03c3\u03c7\u03b5\u03c4\u03af\u03b6\u03b5\u03c4\u03b1\u03b9 \u03bc\u03b5 \u03c4\u03b1 \u03bc\u03b5\u03c4\u03b1-\u03bf\u03be\u03ad\u03b1 \u03b5\u03c0\u03b1\u03ba\u03cc\u03bb\u03bf\u03c5\u03b8\u03b1 \u03c4\u03bf\u03c5 COVID-19 \u03a0\u03c1\u03bf\u03b2\u03bf\u03bb\u03ae \u03a0\u03c1\u03bf\u03c6\u03af\u03bb ORCID Zoe Swank , \u03a0\u03c1\u03bf\u03b2\u03bf\u03bb\u03ae \u03a0\u03c1\u03bf\u03c6\u03af\u03bb ORCID Yasmeen Senussi , Galit Alter , \u03a0\u03c1\u03bf\u03b2\u03bf\u03bb\u03ae \u03a0\u03c1\u03bf\u03c6\u03af\u03bb ORCID David R. Walt doi: https:\/\/doi.org\/10.1101\/2022.06.14.22276401 \u0391\u03c5\u03c4\u03cc \u03c4\u03bf \u03ac\u03c1\u03b8\u03c1\u03bf \u03b5\u03af\u03bd\u03b1\u03b9 \u03c0\u03c1\u03bf\u03b5\u03ba\u03c4\u03cd\u03c0\u03c9\u03c3\u03b7 \u03ba\u03b1\u03b9 \u03b4\u03b5\u03bd \u03ad\u03c7\u03b5\u03b9 \u03b1\u03be\u03b9\u03bf\u03bb\u03bf\u03b3\u03b7\u03b8\u03b5\u03af \u03b1\u03c0\u03cc \u03bf\u03bc\u03bf\u03c4\u03af\u03bc\u03bf\u03c5\u03c2 [\u03c4\u03b9 \u03c3\u03b7\u03bc\u03b1\u03af\u03bd\u03b5\u03b9 \u03b1\u03c5\u03c4\u03cc;]. \u0391\u03bd\u03b1\u03c6\u03ad\u03c1\u03b5\u03b9 \u03bd\u03ad\u03b1 \u03b9\u03b1\u03c4\u03c1\u03b9\u03ba\u03ae \u03ad\u03c1\u03b5\u03c5\u03bd\u03b1 \u03c0\u03bf\u03c5 \u03b4\u03b5\u03bd &hellip; <\/p>\n<p><a class=\"more-link btn\" href=\"https:\/\/evaggelatos.com\/?p=26419\">\u03a3\u03c5\u03bd\u03ad\u03c7\u03b5\u03b9\u03b1 \u03b1\u03bd\u03ac\u03b3\u03bd\u03c9\u03c3\u03b7\u03c2<\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[85],"tags":[217,90],"class_list":["post-26419","post","type-post","status-publish","format-standard","hentry","category-85","tag-217","tag-90","item-wrap"],"_links":{"self":[{"href":"https:\/\/evaggelatos.com\/index.php?rest_route=\/wp\/v2\/posts\/26419","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/evaggelatos.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/evaggelatos.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/evaggelatos.com\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/evaggelatos.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=26419"}],"version-history":[{"count":4,"href":"https:\/\/evaggelatos.com\/index.php?rest_route=\/wp\/v2\/posts\/26419\/revisions"}],"predecessor-version":[{"id":26423,"href":"https:\/\/evaggelatos.com\/index.php?rest_route=\/wp\/v2\/posts\/26419\/revisions\/26423"}],"wp:attachment":[{"href":"https:\/\/evaggelatos.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=26419"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/evaggelatos.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=26419"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/evaggelatos.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=26419"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}