{"id":27277,"date":"2022-08-20T21:49:30","date_gmt":"2022-08-20T21:49:30","guid":{"rendered":"https:\/\/evaggelatos.com\/?p=27277"},"modified":"2022-08-20T22:34:51","modified_gmt":"2022-08-20T22:34:51","slug":"%ce%b5%cf%80%ce%af%ce%bc%ce%bf%ce%bd%ce%b1-%cf%83%cf%85%ce%bc%cf%80%cf%84%cf%8e%ce%bc%ce%b1%cf%84%ce%b1-%cf%83%ce%b5-%ce%b1%cf%83%ce%b8%ce%b5%ce%bd%ce%b5%ce%af%cf%82-%cf%80%ce%bf%cf%85-%ce%b1%cf%83","status":"publish","type":"post","link":"https:\/\/evaggelatos.com\/?p=27277","title":{"rendered":"\u0395\u03c0\u03af\u03bc\u03bf\u03bd\u03b1 \u03c3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03b1 \u03c3\u03b5 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03c0\u03bf\u03c5 \u03b1\u03c3\u03b8\u03ad\u03bd\u03b7\u03c3\u03b1\u03bd \u03bc\u03b5 \u03bf\u03be\u03b5\u03af\u03b1 \u03bd\u03cc\u03c3\u03bf COVID-19"},"content":{"rendered":"
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July 9, 2020<\/div>\n
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Persistent Symptoms in Patients After Acute COVID-19<\/h1>\n<\/div>\n
Angelo\u00a0Carf\u00ec,\u00a0MD1<\/sup><\/a><\/span>;\u00a0<\/span>Roberto\u00a0Bernabei,\u00a0MD1<\/sup><\/a><\/span>;\u00a0<\/span>Francesco\u00a0Landi,\u00a0MD, PhD1<\/sup><\/a><\/span>;\u00a0et al<\/a><\/span>for the Gemelli Against COVID-19 Post-Acute Care Study Group<\/span><\/div>\n
Author Affiliations<\/a>\u00a0Article Information<\/a><\/div>\n
JAMA.\u00a0<\/span>2020;324(6):603-605. doi:10.1001\/jama.2020.12603<\/span><\/div>\n<\/div>\n
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<\/i>COVID-19 Resource Center<\/a><\/div>\n<\/div>\n<\/div>\n
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Audio Clinical Review (19:58)<\/div>\n
What Is It Like to Have COVID-19?<\/a><\/div>\n
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In Italy, a large proportion of patients with coronavirus disease 2019 (COVID-19) presented with symptoms (71.4% of 31\u202f845 confirmed cases as of June 3, 2020).1<\/a><\/sup>\u00a0Common symptoms include cough, fever, dyspnea, musculoskeletal symptoms (myalgia, joint pain, fatigue), gastrointestinal symptoms, and anosmia\/dysgeusia.2<\/a><\/sup>–4<\/a><\/sup>\u00a0However, information is lacking on symptoms that persist after recovery. We assessed persistent symptoms in patients who were discharged from the hospital after recovery from COVID-19.<\/p>\n

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Methods<\/div>\n<\/div>\n

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In the waning phase of the pandemic, beginning on April 21, 2020, the Fondazione Policlinico Universitario Agostino Gemelli IRCCS in Rome, Italy, established a postacute outpatient service for individuals discharged from the hospital after recovery from COVID-19. All patients who met World Health Organization criteria for discontinuation of quarantine (no fever for 3 consecutive days, improvement in other symptoms, and 2 negative test results for severe acute respiratory syndrome coronavirus 2 [SARS-CoV-2] 24 hours apart) were followed up. At enrollment in the study, real-time reverse transcriptase\u2013polymerase chain reaction for SARS-CoV-2 was performed and patients with a negative test result were included.<\/p>\n

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Patients were offered a comprehensive medical assessment with detailed history and physical examination. Data on all clinical characteristics, including clinical and pharmacological history, lifestyle factors, vaccination status, and body measurements, were collected in a structured electronic data collection system. The COVID-19 postacute outpatient service is currently active, and further details about the patient evaluation protocol are described elsewhere.5<\/a><\/sup><\/p>\n

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In particular, data on specific symptoms potentially correlated with COVID-19 were obtained using a standardized questionnaire administered at enrollment. Patients were asked to retrospectively recount the presence or absence of symptoms during the acute phase of COVID-19 and whether each symptom persisted at the time of the visit. More than 1 symptom could be reported. The EuroQol visual analog scale was used to ask patients to score their quality of life from 0 (worst imaginable health) to 100 (best imaginable health) before COVID-19 and at the time of the visit. A difference of 10 points defined worsened quality of life. All analyses were performed using R version 3.6.3 (R Foundation).<\/p>\n

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This study was approved by the Universit\u00e0 Cattolica and Fondazione Policlinico Gemelli IRCCS Institutional Ethics Committee. Written informed consent was obtained from all participants.<\/p>\n

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Results<\/div>\n<\/div>\n

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From April 21 to May 29, 2020, 179 patients were potentially eligible for the follow-up post\u2013acute care assessment; 14 individuals (8%) refused to participate and 22 had a positive test result. Thus, 143 patients were included. The mean age was 56.5 (SD, 14.6) years (range, 19-84 years), and 53 (37%) were women. During hospitalization, 72.7% of participants had evidence of interstitial pneumonia. The mean length of hospital stay was 13.5 (SD, 9.7) days; 21 patients (15%) received noninvasive ventilation and 7 patients (5%) received invasive ventilation. The characteristics of the study population are summarized in the\u00a0Table<\/a>.<\/p>\n

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Patients were assessed a mean of 60.3 (SD, 13.6) days after onset of the first COVID-19 symptom; at the time of the evaluation, only 18 (12.6%) were completely free of any COVID-19\u2013related symptom, while 32% had 1 or 2 symptoms and 55% had 3 or more. None of the patients had fever or any signs or symptoms of acute illness. Worsened quality of life was observed among 44.1% of patients. The\u00a0Figure<\/a>\u00a0shows that a high proportion of individuals still reported fatigue (53.1%), dyspnea (43.4%), joint pain, (27.3%) and chest pain (21.7%).<\/p>\n

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Discussion<\/div>\n<\/div>\n

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This study found that in patients who had recovered from COVID-19, 87.4% reported persistence of at least 1 symptom, particularly fatigue and dyspnea. Limitations of the study include the lack of information on symptom history before acute COVID-19 illness and the lack of details on symptom severity. Furthermore, this is a single-center study with a relatively small number of patients and without a control group of patients discharged for other reasons. Patients with community-acquired pneumonia can also have persistent symptoms, suggesting that these findings may not be exclusive to COVID-19.6<\/a><\/sup><\/p>\n

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Clinicians and researchers have focused on the acute phase of COVID-19, but continued monitoring after discharge for long-lasting effects is needed.<\/p>\n

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Section Editor:<\/strong>\u00a0Jody W. Zylke, MD, Deputy Editor.<\/div>\n

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Back to top<\/a><\/p>\n

Article Information<\/div>\n<\/div>\n

Corresponding Author:<\/strong>\u00a0Angelo Carf\u00ec, MD, Centro Medicina dell\u2019Invecchiamento, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Largo Francesco Vito 1, 00168 Rome, Italy (angelo.carfi@policlinicogemelli.it<\/a>).<\/p>\n

Accepted for Publication:<\/strong>\u00a0June 23, 2020.<\/p>\n

Published Online:<\/strong>\u00a0July 9, 2020. doi:10.1001\/jama.2020.12603<\/a><\/p>\n

Author Contributions:<\/strong>\u00a0Drs Carf\u00ec and Landi had full access to all of the data in the study and take responsibility for the integrity of the data and the accuracy of the data analysis.<\/p>\n

Concept and design:\u00a0<\/i>All authors.<\/p>\n

Drafting of the manuscript:\u00a0<\/i>Carf\u00ec, Landi.<\/p>\n

Critical revision of the manuscript for important intellectual content:<\/i>\u00a0Bernabei, Landi.<\/p>\n

Statistical analysis:\u00a0<\/i>Carf\u00ec.<\/p>\n

Supervision:<\/i>\u00a0Bernabei, Landi.<\/p>\n

Conflict of Interest Disclosures:<\/strong>\u00a0None reported.<\/p>\n

Additional Information:<\/strong>\u00a0The members of the Gemelli Against COVID-19 Post-Acute Care Study Group are listed in reference 5.<\/p>\n

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References<\/div>\n<\/div>\n
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<\/a>1.<\/p>\n

Istituto Superiore Sanit\u00e0.\u00a0Sorveglianza Integrata COVID-19 in Italia<\/i>. Published 2020. Accessed June 8, 2020.\u00a0https:\/\/www.epicentro.iss.it\/coronavirus\/bollettino\/Infografica_3giugno%20ITA.pdf<\/a><\/div>\n<\/div>\n
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<\/a>2.<\/p>\n

Docherty \u00a0AB, Harrison \u00a0EM, Green \u00a0CA, \u00a0et al; ISARIC4C Investigators. \u00a0Features of 20\u202f133 UK patients in hospital with COVID-19 using the ISARIC WHO Clinical Characterisation Protocol: prospective observational cohort study.\u00a0\u00a0\u00a0BMJ<\/i>. 2020;369:m1985. doi:10.1136\/bmj.m1985<\/a>PubMed<\/a>Google Scholar<\/a>Crossref<\/a><\/div>\n<\/div>\n
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<\/a>3.<\/p>\n

Wang \u00a0D, Hu \u00a0B, Hu \u00a0C, \u00a0et al. \u00a0Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus\u2013infected pneumonia in Wuhan, China.\u00a0\u00a0\u00a0JAMA<\/i>. 2020;323(13):1239-1242. doi:10.1001\/jama.2020.1585<\/a>
\nArticle<\/a>PubMed<\/a>Google Scholar<\/a>Crossref<\/a><\/div>\n<\/div>\n
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<\/a>4.<\/p>\n

Landi \u00a0F, Barillaro \u00a0C, Bellieni \u00a0A, \u00a0et al. \u00a0The new challenge of geriatrics: saving frail older people from the SARS-CoV-2 pandemic infection.\u00a0\u00a0\u00a0J Nutr Health Aging<\/i>. 2020;24(5):466-470. doi:10.1007\/s12603-020-1356-x<\/a>PubMed<\/a>Google Scholar<\/a>Crossref<\/a><\/div>\n<\/div>\n
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<\/a>5.<\/p>\n

Gemelli Against COVID-19 Post-Acute Care Study Group. \u00a0Post-COVID-19 global health strategies: the need for an interdisciplinary approach.\u00a0\u00a0\u00a0Aging Clin Exp Res<\/i>. Published online June 11, 2020. doi:10.1007\/s40520-020-01616-x<\/a>PubMed<\/a>Google Scholar<\/a><\/div>\n<\/div>\n
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<\/a>6.<\/p>\n

Metlay \u00a0JP, Fine \u00a0MJ, Schulz \u00a0R, \u00a0et al. \u00a0Measuring symptomatic and functional recovery in patients with community-acquired pneumonia.\u00a0\u00a0\u00a0J Gen Intern Med<\/i>. 1997;12(7):423-430. doi:10.1046\/j.1525-1497.1997.00074.x<\/a>PubMed<\/a>Google Scholar<\/a>Crossref<\/a><\/div>\n
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Angelo Carf\u00ec, MD <\/span>1 <\/span><\/sup><\/a><\/span>; <\/span><\/span>Roberto Bernabei, MD <\/span>1 <\/span><\/sup><\/a><\/span>; <\/span><\/span>Francesco Landi, MD, PhD <\/span>1 <\/span><\/sup><\/a><\/span>; <\/span>et al <\/span><\/a><\/span>\u03b3\u03b9\u03b1 \u03c4\u03b7\u03bd \u03bf\u03bc\u03ac\u03b4\u03b1 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b7\u03c2 Gemelli Against COVID-19 Post-Acute Care <\/span><\/span><\/div>\n
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\u039c\u03ad\u03b8\u03bf\u03b4\u03bf\u03b9 <\/span><\/div>\n<\/div>\n

\u03a3\u03c4\u03b7 \u03c6\u03ac\u03c3\u03b7 \u03cd\u03c6\u03b5\u03c3\u03b7\u03c2 \u03c4\u03b7\u03c2 \u03c0\u03b1\u03bd\u03b4\u03b7\u03bc\u03af\u03b1\u03c2, \u03b1\u03c1\u03c7\u03ae\u03c2 \u03b3\u03b5\u03bd\u03bf\u03bc\u03ad\u03bd\u03b7\u03c2 \u03c3\u03c4\u03b9\u03c2 21 \u0391\u03c0\u03c1\u03b9\u03bb\u03af\u03bf\u03c5 2020, \u03c4\u03bf Fondazione Policlinico Universitario Agostino Gemelli IRCCS \u03c3\u03c4\u03b7 \u03a1\u03ce\u03bc\u03b7, \u0399\u03c4\u03b1\u03bb\u03af\u03b1, \u03af\u03b4\u03c1\u03c5\u03c3\u03b5 \u03bc\u03b9\u03b1 \u03bc\u03b5\u03c4\u03b1\u03b3\u03b5\u03bd\u03ad\u03c3\u03c4\u03b5\u03c1\u03b7 \u03c5\u03c0\u03b7\u03c1\u03b5\u03c3\u03af\u03b1 \u03b5\u03be\u03c9\u03c4\u03b5\u03c1\u03b9\u03ba\u03ce\u03bd \u03b1\u03c3\u03b8\u03b5\u03bd\u03ce\u03bd \u03b3\u03b9\u03b1 \u03ac\u03c4\u03bf\u03bc\u03b1 \u03c0\u03bf\u03c5 \u03b5\u03be\u03ae\u03bb\u03b8\u03b1\u03bd \u03b1\u03c0\u03cc \u03c4\u03bf \u03bd\u03bf\u03c3\u03bf\u03ba\u03bf\u03bc\u03b5\u03af\u03bf \u03bc\u03b5\u03c4\u03ac \u03c4\u03b7\u03bd \u03b1\u03bd\u03ac\u03c1\u03c1\u03c9\u03c3\u03ae \u03c4\u03bf\u03c5\u03c2 \u03b1\u03c0\u03cc \u03c4\u03bf\u03bd COVID-19. \u03a0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03c5\u03b8\u03ae\u03b8\u03b7\u03ba\u03b1\u03bd \u03cc\u03bb\u03bf\u03b9 \u03bf\u03b9 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03c0\u03bf\u03c5 \u03c0\u03bb\u03b7\u03c1\u03bf\u03cd\u03c3\u03b1\u03bd \u03c4\u03b1 \u03ba\u03c1\u03b9\u03c4\u03ae\u03c1\u03b9\u03b1 \u03c4\u03bf\u03c5 \u03a0\u03b1\u03b3\u03ba\u03cc\u03c3\u03bc\u03b9\u03bf\u03c5 \u039f\u03c1\u03b3\u03b1\u03bd\u03b9\u03c3\u03bc\u03bf\u03cd \u03a5\u03b3\u03b5\u03af\u03b1\u03c2 \u03b3\u03b9\u03b1 \u03b4\u03b9\u03b1\u03ba\u03bf\u03c0\u03ae \u03c4\u03b7\u03c2 \u03ba\u03b1\u03c1\u03b1\u03bd\u03c4\u03af\u03bd\u03b1\u03c2 (\u03c7\u03c9\u03c1\u03af\u03c2 \u03c0\u03c5\u03c1\u03b5\u03c4\u03cc \u03b3\u03b9\u03b1 3 \u03c3\u03c5\u03bd\u03b5\u03c7\u03cc\u03bc\u03b5\u03bd\u03b5\u03c2 \u03b7\u03bc\u03ad\u03c1\u03b5\u03c2, \u03b2\u03b5\u03bb\u03c4\u03af\u03c9\u03c3\u03b7 \u03ac\u03bb\u03bb\u03c9\u03bd \u03c3\u03c5\u03bc\u03c0\u03c4\u03c9\u03bc\u03ac\u03c4\u03c9\u03bd \u03ba\u03b1\u03b9 2 \u03b1\u03c1\u03bd\u03b7\u03c4\u03b9\u03ba\u03ac \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03ad\u03c3\u03bc\u03b1\u03c4\u03b1 \u03b5\u03be\u03b5\u03c4\u03ac\u03c3\u03b5\u03c9\u03bd \u03b3\u03b9\u03b1 \u03c3\u03bf\u03b2\u03b1\u03c1\u03cc \u03bf\u03be\u03cd \u03b1\u03bd\u03b1\u03c0\u03bd\u03b5\u03c5\u03c3\u03c4\u03b9\u03ba\u03cc \u03c3\u03cd\u03bd\u03b4\u03c1\u03bf\u03bc\u03bf \u03ba\u03bf\u03c1\u03c9\u03bd\u03bf\u03ca\u03bf\u03cd 2 [SARS-CoV-2] \u03bc\u03b5 \u03b4\u03b9\u03b1\u03c6\u03bf\u03c1\u03ac 24 \u03c9\u03c1\u03ce\u03bd). \u03c0\u03ac\u03bd\u03c9. \u039a\u03b1\u03c4\u03ac \u03c4\u03b7\u03bd \u03b5\u03b3\u03b3\u03c1\u03b1\u03c6\u03ae \u03c3\u03c4\u03b7 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b7, \u03c0\u03c1\u03b1\u03b3\u03bc\u03b1\u03c4\u03bf\u03c0\u03bf\u03b9\u03ae\u03b8\u03b7\u03ba\u03b5 \u03b1\u03bb\u03c5\u03c3\u03b9\u03b4\u03c9\u03c4\u03ae \u03b1\u03bd\u03c4\u03af\u03b4\u03c1\u03b1\u03c3\u03b7 \u03b1\u03bd\u03ac\u03c3\u03c4\u03c1\u03bf\u03c6\u03b7\u03c2 \u03bc\u03b5\u03c4\u03b1\u03b3\u03c1\u03b1\u03c6\u03ac\u03c3\u03b7\u03c2-\u03c0\u03bf\u03bb\u03c5\u03bc\u03b5\u03c1\u03ac\u03c3\u03b7\u03c2 \u03c3\u03b5 \u03c0\u03c1\u03b1\u03b3\u03bc\u03b1\u03c4\u03b9\u03ba\u03cc \u03c7\u03c1\u03cc\u03bd\u03bf \u03b3\u03b9\u03b1 \u03c4\u03bf\u03bd SARS-CoV-2 \u03ba\u03b1\u03b9 \u03c3\u03c5\u03bc\u03c0\u03b5\u03c1\u03b9\u03bb\u03ae\u03c6\u03b8\u03b7\u03ba\u03b1\u03bd \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 \u03b1\u03c1\u03bd\u03b7\u03c4\u03b9\u03ba\u03cc \u03b1\u03c0\u03bf\u03c4\u03ad\u03bb\u03b5\u03c3\u03bc\u03b1 \u03b4\u03bf\u03ba\u03b9\u03bc\u03ae\u03c2. <\/span><\/p>\n

\u03a3\u03c4\u03bf\u03c5\u03c2 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03c0\u03c1\u03bf\u03c3\u03c6\u03ad\u03c1\u03b8\u03b7\u03ba\u03b5 \u03bc\u03b9\u03b1 \u03bf\u03bb\u03bf\u03ba\u03bb\u03b7\u03c1\u03c9\u03bc\u03ad\u03bd\u03b7 \u03b9\u03b1\u03c4\u03c1\u03b9\u03ba\u03ae \u03b1\u03be\u03b9\u03bf\u03bb\u03cc\u03b3\u03b7\u03c3\u03b7 \u03bc\u03b5 \u03bb\u03b5\u03c0\u03c4\u03bf\u03bc\u03b5\u03c1\u03ad\u03c2 \u03b9\u03c3\u03c4\u03bf\u03c1\u03b9\u03ba\u03cc \u03ba\u03b1\u03b9 \u03c6\u03c5\u03c3\u03b9\u03ba\u03ae \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7. \u0394\u03b5\u03b4\u03bf\u03bc\u03ad\u03bd\u03b1 \u03b3\u03b9\u03b1 \u03cc\u03bb\u03b1 \u03c4\u03b1 \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ac \u03c7\u03b1\u03c1\u03b1\u03ba\u03c4\u03b7\u03c1\u03b9\u03c3\u03c4\u03b9\u03ba\u03ac, \u03c3\u03c5\u03bc\u03c0\u03b5\u03c1\u03b9\u03bb\u03b1\u03bc\u03b2\u03b1\u03bd\u03bf\u03bc\u03ad\u03bd\u03bf\u03c5 \u03c4\u03bf\u03c5 \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03bf\u03cd \u03ba\u03b1\u03b9 \u03c6\u03b1\u03c1\u03bc\u03b1\u03ba\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03bf\u03cd \u03b9\u03c3\u03c4\u03bf\u03c1\u03b9\u03ba\u03bf\u03cd, \u03c4\u03c9\u03bd \u03c0\u03b1\u03c1\u03b1\u03b3\u03cc\u03bd\u03c4\u03c9\u03bd \u03c4\u03c1\u03cc\u03c0\u03bf\u03c5 \u03b6\u03c9\u03ae\u03c2, \u03c4\u03b7\u03c2 \u03b5\u03bc\u03b2\u03bf\u03bb\u03b9\u03b1\u03c3\u03c4\u03b9\u03ba\u03ae\u03c2 \u03ba\u03b1\u03c4\u03ac\u03c3\u03c4\u03b1\u03c3\u03b7\u03c2 \u03ba\u03b1\u03b9 \u03c4\u03c9\u03bd \u03c3\u03c9\u03bc\u03b1\u03c4\u03b9\u03ba\u03ce\u03bd \u03bc\u03b5\u03c4\u03c1\u03ae\u03c3\u03b5\u03c9\u03bd, \u03c3\u03c5\u03bb\u03bb\u03ad\u03c7\u03b8\u03b7\u03ba\u03b1\u03bd \u03c3\u03b5 \u03ad\u03bd\u03b1 \u03b4\u03bf\u03bc\u03b7\u03bc\u03ad\u03bd\u03bf \u03b7\u03bb\u03b5\u03ba\u03c4\u03c1\u03bf\u03bd\u03b9\u03ba\u03cc \u03c3\u03cd\u03c3\u03c4\u03b7\u03bc\u03b1 \u03c3\u03c5\u03bb\u03bb\u03bf\u03b3\u03ae\u03c2 \u03b4\u03b5\u03b4\u03bf\u03bc\u03ad\u03bd\u03c9\u03bd. \u0397 \u03c5\u03c0\u03b7\u03c1\u03b5\u03c3\u03af\u03b1 \u03b5\u03be\u03c9\u03c4\u03b5\u03c1\u03b9\u03ba\u03ce\u03bd \u03b1\u03c3\u03b8\u03b5\u03bd\u03ce\u03bd \u03bc\u03b5\u03c4\u03ac \u03c4\u03b7\u03bd \u03bf\u03be\u03b5\u03af\u03b1 \u03bd\u03cc\u03c3\u03bf COVID-19 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b5\u03bd\u03b5\u03c1\u03b3\u03ae \u03b1\u03c5\u03c4\u03ae \u03c4\u03b7 \u03c3\u03c4\u03b9\u03b3\u03bc\u03ae \u03ba\u03b1\u03b9 \u03c0\u03b5\u03c1\u03b9\u03c3\u03c3\u03cc\u03c4\u03b5\u03c1\u03b5\u03c2 \u03bb\u03b5\u03c0\u03c4\u03bf\u03bc\u03ad\u03c1\u03b5\u03b9\u03b5\u03c2 \u03c3\u03c7\u03b5\u03c4\u03b9\u03ba\u03ac \u03bc\u03b5 \u03c4\u03bf \u03c0\u03c1\u03c9\u03c4\u03cc\u03ba\u03bf\u03bb\u03bb\u03bf \u03b1\u03be\u03b9\u03bf\u03bb\u03cc\u03b3\u03b7\u03c3\u03b7\u03c2 \u03b1\u03c3\u03b8\u03b5\u03bd\u03ce\u03bd \u03c0\u03b5\u03c1\u03b9\u03b3\u03c1\u03ac\u03c6\u03bf\u03bd\u03c4\u03b1\u03b9 \u03b1\u03bb\u03bb\u03bf\u03cd. <\/span>5 <\/span><\/a><\/sup><\/p>\n

\u03a3\u03c5\u03b3\u03ba\u03b5\u03ba\u03c1\u03b9\u03bc\u03ad\u03bd\u03b1, \u03b4\u03b5\u03b4\u03bf\u03bc\u03ad\u03bd\u03b1 \u03c3\u03c7\u03b5\u03c4\u03b9\u03ba\u03ac \u03bc\u03b5 \u03c3\u03c5\u03b3\u03ba\u03b5\u03ba\u03c1\u03b9\u03bc\u03ad\u03bd\u03b1 \u03c3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03b1 \u03c0\u03bf\u03c5 \u03b4\u03c5\u03bd\u03b7\u03c4\u03b9\u03ba\u03ac \u03c3\u03c5\u03c3\u03c7\u03b5\u03c4\u03af\u03b6\u03bf\u03bd\u03c4\u03b1\u03b9 \u03bc\u03b5 \u03c4\u03bf\u03bd COVID-19 \u03b5\u03bb\u03ae\u03c6\u03b8\u03b7\u03c3\u03b1\u03bd \u03c7\u03c1\u03b7\u03c3\u03b9\u03bc\u03bf\u03c0\u03bf\u03b9\u03ce\u03bd\u03c4\u03b1\u03c2 \u03ad\u03bd\u03b1 \u03c4\u03c5\u03c0\u03bf\u03c0\u03bf\u03b9\u03b7\u03bc\u03ad\u03bd\u03bf \u03b5\u03c1\u03c9\u03c4\u03b7\u03bc\u03b1\u03c4\u03bf\u03bb\u03cc\u03b3\u03b9\u03bf \u03c0\u03bf\u03c5 \u03c7\u03bf\u03c1\u03b7\u03b3\u03ae\u03b8\u03b7\u03ba\u03b5 \u03ba\u03b1\u03c4\u03ac \u03c4\u03b7\u03bd \u03b5\u03b3\u03b3\u03c1\u03b1\u03c6\u03ae. \u0396\u03b7\u03c4\u03ae\u03b8\u03b7\u03ba\u03b5 \u03b1\u03c0\u03cc \u03c4\u03bf\u03c5\u03c2 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bd\u03b1 \u03b1\u03bd\u03b1\u03c6\u03ad\u03c1\u03bf\u03c5\u03bd \u03b1\u03bd\u03b1\u03b4\u03c1\u03bf\u03bc\u03b9\u03ba\u03ac \u03c4\u03b7\u03bd \u03c0\u03b1\u03c1\u03bf\u03c5\u03c3\u03af\u03b1 \u03ae \u03c4\u03b7\u03bd \u03b1\u03c0\u03bf\u03c5\u03c3\u03af\u03b1 \u03c3\u03c5\u03bc\u03c0\u03c4\u03c9\u03bc\u03ac\u03c4\u03c9\u03bd \u03ba\u03b1\u03c4\u03ac \u03c4\u03b7\u03bd \u03bf\u03be\u03b5\u03af\u03b1 \u03c6\u03ac\u03c3\u03b7 \u03c4\u03bf\u03c5 COVID-19 \u03ba\u03b1\u03b9 \u03b5\u03ac\u03bd \u03ba\u03ac\u03b8\u03b5 \u03c3\u03cd\u03bc\u03c0\u03c4\u03c9\u03bc\u03b1 \u03c0\u03b1\u03c1\u03ad\u03bc\u03b5\u03b9\u03bd\u03b5 \u03ba\u03b1\u03c4\u03ac \u03c4\u03b7 \u03c3\u03c4\u03b9\u03b3\u03bc\u03ae \u03c4\u03b7\u03c2 \u03b5\u03c0\u03af\u03c3\u03ba\u03b5\u03c8\u03b7\u03c2. \u0398\u03b1 \u03bc\u03c0\u03bf\u03c1\u03bf\u03cd\u03c3\u03b1\u03bd \u03bd\u03b1 \u03b1\u03bd\u03b1\u03c6\u03b5\u03c1\u03b8\u03bf\u03cd\u03bd \u03c0\u03b5\u03c1\u03b9\u03c3\u03c3\u03cc\u03c4\u03b5\u03c1\u03b1 \u03b1\u03c0\u03cc 1 \u03c3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03b1. \u0397 \u03bf\u03c0\u03c4\u03b9\u03ba\u03ae \u03b1\u03bd\u03b1\u03bb\u03bf\u03b3\u03b9\u03ba\u03ae \u03ba\u03bb\u03af\u03bc\u03b1\u03ba\u03b1 EuroQol \u03c7\u03c1\u03b7\u03c3\u03b9\u03bc\u03bf\u03c0\u03bf\u03b9\u03ae\u03b8\u03b7\u03ba\u03b5 \u03b3\u03b9\u03b1 \u03bd\u03b1 \u03b6\u03b7\u03c4\u03b7\u03b8\u03b5\u03af \u03b1\u03c0\u03cc \u03c4\u03bf\u03c5\u03c2 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bd\u03b1 \u03b2\u03b1\u03b8\u03bc\u03bf\u03bb\u03bf\u03b3\u03ae\u03c3\u03bf\u03c5\u03bd \u03c4\u03b7\u03bd \u03c0\u03bf\u03b9\u03cc\u03c4\u03b7\u03c4\u03b1 \u03b6\u03c9\u03ae\u03c2 \u03c4\u03bf\u03c5\u03c2 \u03b1\u03c0\u03cc 0 (\u03c7\u03b5\u03b9\u03c1\u03cc\u03c4\u03b5\u03c1\u03b7 \u03c5\u03b3\u03b5\u03af\u03b1) \u03ad\u03c9\u03c2 100 (\u03ba\u03b1\u03bb\u03cd\u03c4\u03b5\u03c1\u03b7 \u03c5\u03b3\u03b5\u03af\u03b1 \u03c0\u03bf\u03c5 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03ba\u03b1\u03bd\u03b5\u03af\u03c2 \u03bd\u03b1 \u03c6\u03b1\u03bd\u03c4\u03b1\u03c3\u03c4\u03b5\u03af) \u03c0\u03c1\u03b9\u03bd \u03b1\u03c0\u03cc \u03c4\u03bf\u03bd COVID-19 \u03ba\u03b1\u03b9 \u03c4\u03b7 \u03c3\u03c4\u03b9\u03b3\u03bc\u03ae \u03c4\u03b7\u03c2 \u03b5\u03c0\u03af\u03c3\u03ba\u03b5\u03c8\u03b7\u03c2. \u039c\u03b9\u03b1 \u03b4\u03b9\u03b1\u03c6\u03bf\u03c1\u03ac 10 \u03b2\u03b1\u03b8\u03bc\u03ce\u03bd \u03ba\u03b1\u03b8\u03cc\u03c1\u03b9\u03c3\u03b5 \u03b5\u03c0\u03b9\u03b4\u03b5\u03af\u03bd\u03c9\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03c0\u03bf\u03b9\u03cc\u03c4\u03b7\u03c4\u03b1\u03c2 \u03b6\u03c9\u03ae\u03c2. \u038c\u03bb\u03b5\u03c2 \u03bf\u03b9 \u03b1\u03bd\u03b1\u03bb\u03cd\u03c3\u03b5\u03b9\u03c2 \u03c0\u03c1\u03b1\u03b3\u03bc\u03b1\u03c4\u03bf\u03c0\u03bf\u03b9\u03ae\u03b8\u03b7\u03ba\u03b1\u03bd \u03c7\u03c1\u03b7\u03c3\u03b9\u03bc\u03bf\u03c0\u03bf\u03b9\u03ce\u03bd\u03c4\u03b1\u03c2 R \u03ad\u03ba\u03b4\u03bf\u03c3\u03b7 3.6.3 (R Foundation). <\/span><\/p>\n

\u0391\u03c5\u03c4\u03ae \u03b7 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b7 \u03b5\u03b3\u03ba\u03c1\u03af\u03b8\u03b7\u03ba\u03b5 \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd \u0395\u03c0\u03b9\u03c4\u03c1\u03bf\u03c0\u03ae \u0398\u03b5\u03c3\u03bc\u03b9\u03ba\u03ae\u03c2 \u0394\u03b5\u03bf\u03bd\u03c4\u03bf\u03bb\u03bf\u03b3\u03af\u03b1\u03c2 \u03c4\u03bf\u03c5 Universit\u00e0 Cattolica \u03ba\u03b1\u03b9 \u03c4\u03bf\u03c5 Fondazione Policlinico Gemelli IRCCS. \u0395\u03bb\u03ae\u03c6\u03b8\u03b7 \u03b3\u03c1\u03b1\u03c0\u03c4\u03ae \u03b5\u03bd\u03b7\u03bc\u03b5\u03c1\u03c9\u03bc\u03ad\u03bd\u03b7 \u03c3\u03c5\u03b3\u03ba\u03b1\u03c4\u03ac\u03b8\u03b5\u03c3\u03b7 \u03b1\u03c0\u03cc \u03cc\u03bb\u03bf\u03c5\u03c2 \u03c4\u03bf\u03c5\u03c2 \u03c3\u03c5\u03bc\u03bc\u03b5\u03c4\u03ad\u03c7\u03bf\u03bd\u03c4\u03b5\u03c2. <\/span><\/p>\n

\n
\u0391\u03c0\u03bf\u03c4\u03b5\u03bb\u03ad\u03c3\u03bc\u03b1\u03c4\u03b1 <\/span><\/div>\n<\/div>\n

\u0391\u03c0\u03cc \u03c4\u03b9\u03c2 21 \u0391\u03c0\u03c1\u03b9\u03bb\u03af\u03bf\u03c5 \u03ad\u03c9\u03c2 \u03c4\u03b9\u03c2 29 \u039c\u03b1\u0390\u03bf\u03c5 2020, 179 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03ae\u03c4\u03b1\u03bd \u03b4\u03c5\u03bd\u03b7\u03c4\u03b9\u03ba\u03ac \u03b5\u03c0\u03b9\u03bb\u03ad\u03be\u03b9\u03bc\u03bf\u03b9 \u03b3\u03b9\u03b1 \u03c4\u03b7\u03bd \u03b1\u03be\u03b9\u03bf\u03bb\u03cc\u03b3\u03b7\u03c3\u03b7 \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03cd\u03b8\u03b7\u03c3\u03b7\u03c2 \u03bc\u03b5\u03c4\u03ac \u03c4\u03b7\u03bd \u03bf\u03be\u03b5\u03af\u03b1 \u03c6\u03c1\u03bf\u03bd\u03c4\u03af\u03b4\u03b1. 14 \u03ac\u03c4\u03bf\u03bc\u03b1 (8%) \u03b1\u03c1\u03bd\u03ae\u03b8\u03b7\u03ba\u03b1\u03bd \u03bd\u03b1 \u03c3\u03c5\u03bc\u03bc\u03b5\u03c4\u03ac\u03c3\u03c7\u03bf\u03c5\u03bd \u03ba\u03b1\u03b9 22 \u03b5\u03af\u03c7\u03b1\u03bd \u03b8\u03b5\u03c4\u03b9\u03ba\u03cc \u03b1\u03c0\u03bf\u03c4\u03ad\u03bb\u03b5\u03c3\u03bc\u03b1 \u03c3\u03c4\u03bf \u03c4\u03b5\u03c3\u03c4. \u0388\u03c4\u03c3\u03b9 \u03c3\u03c5\u03bc\u03c0\u03b5\u03c1\u03b9\u03bb\u03ae\u03c6\u03b8\u03b7\u03ba\u03b1\u03bd 143 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2. \u0397 \u03bc\u03ad\u03c3\u03b7 \u03b7\u03bb\u03b9\u03ba\u03af\u03b1 \u03ae\u03c4\u03b1\u03bd 56,5 (SD, 14,6) \u03ad\u03c4\u03b7 (\u03b5\u03cd\u03c1\u03bf\u03c2, 19-84 \u03ad\u03c4\u03b7) \u03ba\u03b1\u03b9 53 (37%) \u03ae\u03c4\u03b1\u03bd \u03b3\u03c5\u03bd\u03b1\u03af\u03ba\u03b5\u03c2. \u039a\u03b1\u03c4\u03ac \u03c4\u03b7 \u03b4\u03b9\u03ac\u03c1\u03ba\u03b5\u03b9\u03b1 \u03c4\u03b7\u03c2 \u03bd\u03bf\u03c3\u03b7\u03bb\u03b5\u03af\u03b1\u03c2, \u03c4\u03bf 72,7% \u03c4\u03c9\u03bd \u03c3\u03c5\u03bc\u03bc\u03b5\u03c4\u03b5\u03c7\u03cc\u03bd\u03c4\u03c9\u03bd \u03b5\u03af\u03c7\u03b5 \u03b5\u03bd\u03b4\u03b5\u03af\u03be\u03b5\u03b9\u03c2 \u03b4\u03b9\u03ac\u03bc\u03b5\u03c3\u03b7\u03c2 \u03c0\u03bd\u03b5\u03c5\u03bc\u03bf\u03bd\u03af\u03b1\u03c2. \u0397 \u03bc\u03ad\u03c3\u03b7 \u03b4\u03b9\u03ac\u03c1\u03ba\u03b5\u03b9\u03b1 \u03c0\u03b1\u03c1\u03b1\u03bc\u03bf\u03bd\u03ae\u03c2 \u03c3\u03c4\u03bf \u03bd\u03bf\u03c3\u03bf\u03ba\u03bf\u03bc\u03b5\u03af\u03bf \u03ae\u03c4\u03b1\u03bd 13,5 (SD, 9,7) \u03b7\u03bc\u03ad\u03c1\u03b5\u03c2. 21 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 (15%) \u03ad\u03bb\u03b1\u03b2\u03b1\u03bd \u03bc\u03b7 \u03b5\u03c0\u03b5\u03bc\u03b2\u03b1\u03c4\u03b9\u03ba\u03cc \u03b1\u03b5\u03c1\u03b9\u03c3\u03bc\u03cc \u03ba\u03b1\u03b9 7 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 (5%) \u03ad\u03bb\u03b1\u03b2\u03b1\u03bd \u03b5\u03c0\u03b5\u03bc\u03b2\u03b1\u03c4\u03b9\u03ba\u03cc \u03b1\u03b5\u03c1\u03b9\u03c3\u03bc\u03cc. \u03a4\u03b1 \u03c7\u03b1\u03c1\u03b1\u03ba\u03c4\u03b7\u03c1\u03b9\u03c3\u03c4\u03b9\u03ba\u03ac \u03c4\u03bf\u03c5 \u03c0\u03bb\u03b7\u03b8\u03c5\u03c3\u03bc\u03bf\u03cd \u03c4\u03b7\u03c2 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b7\u03c2 \u03c3\u03c5\u03bd\u03bf\u03c8\u03af\u03b6\u03bf\u03bd\u03c4\u03b1\u03b9 \u03c3\u03c4\u03bf\u03bd <\/span>\u03a0\u03af\u03bd\u03b1\u03ba\u03b1 <\/span><\/a>. <\/span><\/p>\n

\u039f\u03b9 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03b1\u03be\u03b9\u03bf\u03bb\u03bf\u03b3\u03ae\u03b8\u03b7\u03ba\u03b1\u03bd \u03ba\u03b1\u03c4\u03ac \u03bc\u03ad\u03c3\u03bf \u03cc\u03c1\u03bf 60,3 (SD, 13,6) \u03b7\u03bc\u03ad\u03c1\u03b5\u03c2 \u03bc\u03b5\u03c4\u03ac \u03c4\u03b7\u03bd \u03b5\u03bc\u03c6\u03ac\u03bd\u03b9\u03c3\u03b7 \u03c4\u03bf\u03c5 \u03c0\u03c1\u03ce\u03c4\u03bf\u03c5 \u03c3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03bf\u03c2 COVID-19. \u03c4\u03b7 \u03c3\u03c4\u03b9\u03b3\u03bc\u03ae \u03c4\u03b7\u03c2 \u03b1\u03be\u03b9\u03bf\u03bb\u03cc\u03b3\u03b7\u03c3\u03b7\u03c2, \u03bc\u03cc\u03bd\u03bf 18 (12,6%) \u03ae\u03c4\u03b1\u03bd \u03b5\u03bd\u03c4\u03b5\u03bb\u03ce\u03c2 \u03b1\u03c0\u03b1\u03bb\u03bb\u03b1\u03b3\u03bc\u03ad\u03bd\u03bf\u03b9 \u03b1\u03c0\u03cc \u03bf\u03c0\u03bf\u03b9\u03bf\u03b4\u03ae\u03c0\u03bf\u03c4\u03b5 \u03c3\u03cd\u03bc\u03c0\u03c4\u03c9\u03bc\u03b1 \u03c0\u03bf\u03c5 \u03c3\u03c7\u03b5\u03c4\u03af\u03b6\u03b5\u03c4\u03b1\u03b9 \u03bc\u03b5 \u03c4\u03bf\u03bd COVID-19, \u03b5\u03bd\u03ce \u03c4\u03bf 32% \u03b5\u03af\u03c7\u03b5 1 \u03ae 2 \u03c3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03b1 \u03ba\u03b1\u03b9 \u03c4\u03bf 55% \u03b5\u03af\u03c7\u03b5 3 \u03ae \u03c0\u03b5\u03c1\u03b9\u03c3\u03c3\u03cc\u03c4\u03b5\u03c1\u03b1. \u039a\u03b1\u03bd\u03ad\u03bd\u03b1\u03c2 \u03b1\u03c0\u03cc \u03c4\u03bf\u03c5\u03c2 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03b4\u03b5\u03bd \u03b5\u03af\u03c7\u03b5 \u03c0\u03c5\u03c1\u03b5\u03c4\u03cc \u03ae \u03c3\u03b7\u03bc\u03b5\u03af\u03b1 \u03ae \u03c3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03b1 \u03bf\u03be\u03b5\u03af\u03b1\u03c2 \u03b1\u03c3\u03b8\u03ad\u03bd\u03b5\u03b9\u03b1\u03c2. \u0395\u03c0\u03b9\u03b4\u03b5\u03b9\u03bd\u03c9\u03bc\u03ad\u03bd\u03b7 \u03c0\u03bf\u03b9\u03cc\u03c4\u03b7\u03c4\u03b1 \u03b6\u03c9\u03ae\u03c2 \u03c0\u03b1\u03c1\u03b1\u03c4\u03b7\u03c1\u03ae\u03b8\u03b7\u03ba\u03b5 \u03c3\u03c4\u03bf 44,1% \u03c4\u03c9\u03bd \u03b1\u03c3\u03b8\u03b5\u03bd\u03ce\u03bd. \u03a4\u03bf <\/span>\u03a3\u03c7\u03ae\u03bc\u03b1 <\/span><\/a>\u03b4\u03b5\u03af\u03c7\u03bd\u03b5\u03b9 \u03cc\u03c4\u03b9 \u03ad\u03bd\u03b1 \u03c5\u03c8\u03b7\u03bb\u03cc \u03c0\u03bf\u03c3\u03bf\u03c3\u03c4\u03cc \u03b1\u03c4\u03cc\u03bc\u03c9\u03bd \u03b1\u03bd\u03ad\u03c6\u03b5\u03c1\u03b5 \u03b1\u03ba\u03cc\u03bc\u03b7 \u03ba\u03cc\u03c0\u03c9\u03c3\u03b7 (53,1%), \u03b4\u03cd\u03c3\u03c0\u03bd\u03bf\u03b9\u03b1 (43,4%), \u03c0\u03cc\u03bd\u03bf \u03c3\u03c4\u03b9\u03c2 \u03b1\u03c1\u03b8\u03c1\u03ce\u03c3\u03b5\u03b9\u03c2 (27,3%) \u03ba\u03b1\u03b9 \u03c0\u03cc\u03bd\u03bf \u03c3\u03c4\u03bf \u03c3\u03c4\u03ae\u03b8\u03bf\u03c2 (21,7%).<\/strong> <\/span><\/p>\n

\n
\u03a3\u03c5\u03b6\u03ae\u03c4\u03b7\u03c3\u03b7 <\/span><\/div>\n<\/div>\n

\u0391\u03c5\u03c4\u03ae \u03b7 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b7 \u03b4\u03b9\u03b1\u03c0\u03af\u03c3\u03c4\u03c9\u03c3\u03b5 \u03cc\u03c4\u03b9 \u03c3\u03b5 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03c0\u03bf\u03c5 \u03b5\u03af\u03c7\u03b1\u03bd \u03b1\u03bd\u03b1\u03c1\u03c1\u03ce\u03c3\u03b5\u03b9 \u03b1\u03c0\u03cc \u03c4\u03bf\u03bd COVID-19, \u03c4\u03bf 87,4% \u03b1\u03bd\u03ad\u03c6\u03b5\u03c1\u03b5 \u03b5\u03c0\u03b9\u03bc\u03bf\u03bd\u03ae \u03c4\u03bf\u03c5\u03bb\u03ac\u03c7\u03b9\u03c3\u03c4\u03bf\u03bd \u03b5\u03bd\u03cc\u03c2 \u03c3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03bf\u03c2, \u03b9\u03b4\u03b9\u03b1\u03af\u03c4\u03b5\u03c1\u03b1 \u03ba\u03cc\u03c0\u03c9\u03c3\u03b7\u03c2 \u03ba\u03b1\u03b9 \u03b4\u03cd\u03c3\u03c0\u03bd\u03bf\u03b9\u03b1\u03c2. \u039f\u03b9 \u03c0\u03b5\u03c1\u03b9\u03bf\u03c1\u03b9\u03c3\u03bc\u03bf\u03af \u03c4\u03b7\u03c2 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b7\u03c2 \u03c0\u03b5\u03c1\u03b9\u03bb\u03b1\u03bc\u03b2\u03ac\u03bd\u03bf\u03c5\u03bd \u03c4\u03b7\u03bd \u03ad\u03bb\u03bb\u03b5\u03b9\u03c8\u03b7 \u03c0\u03bb\u03b7\u03c1\u03bf\u03c6\u03bf\u03c1\u03b9\u03ce\u03bd \u03c3\u03c7\u03b5\u03c4\u03b9\u03ba\u03ac \u03bc\u03b5 \u03c4\u03bf \u03b9\u03c3\u03c4\u03bf\u03c1\u03b9\u03ba\u03cc \u03c3\u03c5\u03bc\u03c0\u03c4\u03c9\u03bc\u03ac\u03c4\u03c9\u03bd \u03c0\u03c1\u03b9\u03bd \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd \u03bf\u03be\u03b5\u03af\u03b1 \u03b1\u03c3\u03b8\u03ad\u03bd\u03b5\u03b9\u03b1 COVID-19 \u03ba\u03b1\u03b9 \u03c4\u03b7\u03bd \u03ad\u03bb\u03bb\u03b5\u03b9\u03c8\u03b7 \u03bb\u03b5\u03c0\u03c4\u03bf\u03bc\u03b5\u03c1\u03b5\u03b9\u03ce\u03bd \u03c3\u03c7\u03b5\u03c4\u03b9\u03ba\u03ac \u03bc\u03b5 \u03c4\u03b7 \u03c3\u03bf\u03b2\u03b1\u03c1\u03cc\u03c4\u03b7\u03c4\u03b1 \u03c4\u03c9\u03bd \u03c3\u03c5\u03bc\u03c0\u03c4\u03c9\u03bc\u03ac\u03c4\u03c9\u03bd. \u0395\u03c0\u03b9\u03c0\u03bb\u03ad\u03bf\u03bd, \u03b1\u03c5\u03c4\u03ae \u03b5\u03af\u03bd\u03b1\u03b9 \u03bc\u03b9\u03b1 \u03bc\u03bf\u03bd\u03bf\u03ba\u03b5\u03bd\u03c4\u03c1\u03b9\u03ba\u03ae \u03bc\u03b5\u03bb\u03ad\u03c4\u03b7 \u03bc\u03b5 \u03c3\u03c7\u03b5\u03c4\u03b9\u03ba\u03ac \u03bc\u03b9\u03ba\u03c1\u03cc \u03b1\u03c1\u03b9\u03b8\u03bc\u03cc \u03b1\u03c3\u03b8\u03b5\u03bd\u03ce\u03bd \u03ba\u03b1\u03b9 \u03c7\u03c9\u03c1\u03af\u03c2 \u03bf\u03bc\u03ac\u03b4\u03b1 \u03b1\u03c3\u03b8\u03b5\u03bd\u03ce\u03bd \u03c0\u03bf\u03c5 \u03b5\u03be\u03ae\u03bb\u03b8\u03b5 \u03b3\u03b9\u03b1 \u03ac\u03bb\u03bb\u03bf\u03c5\u03c2 \u03bb\u03cc\u03b3\u03bf\u03c5\u03c2. \u039f\u03b9 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 \u03c0\u03bd\u03b5\u03c5\u03bc\u03bf\u03bd\u03af\u03b1 \u03c4\u03b7\u03c2 \u03ba\u03bf\u03b9\u03bd\u03cc\u03c4\u03b7\u03c4\u03b1\u03c2 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03b5\u03c0\u03af\u03c3\u03b7\u03c2 \u03bd\u03b1 \u03ad\u03c7\u03bf\u03c5\u03bd \u03b5\u03c0\u03af\u03bc\u03bf\u03bd\u03b1 \u03c3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03b1, \u03c5\u03c0\u03bf\u03b4\u03b7\u03bb\u03ce\u03bd\u03bf\u03bd\u03c4\u03b1\u03c2 \u03cc\u03c4\u03b9 \u03b1\u03c5\u03c4\u03ac \u03c4\u03b1 \u03b5\u03c5\u03c1\u03ae\u03bc\u03b1\u03c4\u03b1 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03bc\u03b7\u03bd \u03b5\u03af\u03bd\u03b1\u03b9 \u03b1\u03c0\u03bf\u03ba\u03bb\u03b5\u03b9\u03c3\u03c4\u03b9\u03ba\u03ac \u03c4\u03bf\u03c5 COVID-19. <\/span>6 <\/span><\/a><\/sup><\/p>\n

\u039f\u03b9 \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03bf\u03af \u03b3\u03b9\u03b1\u03c4\u03c1\u03bf\u03af \u03ba\u03b1\u03b9 \u03bf\u03b9 \u03b5\u03c1\u03b5\u03c5\u03bd\u03b7\u03c4\u03ad\u03c2 \u03ad\u03c7\u03bf\u03c5\u03bd \u03b5\u03c0\u03b9\u03ba\u03b5\u03bd\u03c4\u03c1\u03c9\u03b8\u03b5\u03af \u03c3\u03c4\u03b7\u03bd \u03bf\u03be\u03b5\u03af\u03b1 \u03c6\u03ac\u03c3\u03b7 \u03c4\u03bf\u03c5 COVID-19, \u03b1\u03bb\u03bb\u03ac \u03b1\u03c0\u03b1\u03b9\u03c4\u03b5\u03af\u03c4\u03b1\u03b9 \u03c3\u03c5\u03bd\u03b5\u03c7\u03ae\u03c2 \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03cd\u03b8\u03b7\u03c3\u03b7 \u03bc\u03b5\u03c4\u03ac \u03c4\u03bf \u03b5\u03be\u03b9\u03c4\u03ae\u03c1\u03b9\u03bf \u03b3\u03b9\u03b1 \u03bc\u03b1\u03ba\u03c1\u03bf\u03c7\u03c1\u03cc\u03bd\u03b9\u03b5\u03c2 \u03b5\u03c0\u03b9\u03c0\u03c4\u03ce\u03c3\u03b5\u03b9\u03c2. <\/span><\/p>\n

\u0395\u03c0\u03b9\u03bc\u03ad\u03bb\u03b5\u03b9\u03b1 \u0395\u03bd\u03cc\u03c4\u03b7\u03c4\u03b1\u03c2: <\/span><\/strong>Jody W. Zylke, MD, \u0391\u03bd\u03b1\u03c0\u03bb\u03b7\u03c1\u03c9\u03c4\u03ae\u03c2 \u03a3\u03c5\u03bd\u03c4\u03ac\u03ba\u03c4\u03b7\u03c2. <\/span><\/div>\n

 <\/p>\n

\u0395\u03c0\u03b9\u03c3\u03c4\u03c1\u03bf\u03c6\u03ae \u03c3\u03c4\u03b7\u03bd \u03ba\u03bf\u03c1\u03c5\u03c6\u03ae <\/span><\/a> <\/p>\n
\u03a0\u03bb\u03b7\u03c1\u03bf\u03c6\u03bf\u03c1\u03af\u03b5\u03c2 \u03ac\u03c1\u03b8\u03c1\u03bf\u03c5 <\/span><\/div>\n<\/div>\n

\u0391\u03bd\u03c4\u03af\u03c3\u03c4\u03bf\u03b9\u03c7\u03bf\u03c2 \u03a3\u03c5\u03b3\u03b3\u03c1\u03b1\u03c6\u03ad\u03b1\u03c2: <\/span><\/strong>Angelo Carf\u00ec, MD, Aging Medicine Center, Agostino Gemelli University Hospital Foundation IRCCS, Largo Francesco Vito 1, 00168 \u03a1\u03ce\u03bc\u03b7, \u0399\u03c4\u03b1\u03bb\u03af\u03b1 ( <\/span>angelo.carfi@policlinicogemelli.it <\/span><\/a>). <\/span><\/p>\n

\u0391\u03c0\u03bf\u03b4\u03b5\u03ba\u03c4\u03cc \u03b3\u03b9\u03b1 \u03b4\u03b7\u03bc\u03bf\u03c3\u03af\u03b5\u03c5\u03c3\u03b7: <\/span><\/strong>23 \u0399\u03bf\u03c5\u03bd\u03af\u03bf\u03c5 2020. <\/span><\/p>\n

\u0394\u03b7\u03bc\u03bf\u03c3\u03b9\u03b5\u03cd\u03b8\u03b7\u03ba\u03b5 \u03c3\u03c4\u03bf \u0394\u03b9\u03b1\u03b4\u03af\u03ba\u03c4\u03c5\u03bf: <\/span><\/strong>9 \u0399\u03bf\u03c5\u03bb\u03af\u03bf\u03c5 2020. doi: <\/span>10.1001\/jama.2020.12603 <\/span><\/a><\/p>\n

\u03a3\u03c5\u03bd\u03b5\u03b9\u03c3\u03c6\u03bf\u03c1\u03ad\u03c2 \u03c4\u03bf\u03c5 \u03c3\u03c5\u03b3\u03b3\u03c1\u03b1\u03c6\u03ad\u03b1: \u039f\u03b9 <\/span><\/strong>\u0394\u03c1 Carf\u00ec \u03ba\u03b1\u03b9 Landi \u03b5\u03af\u03c7\u03b1\u03bd \u03c0\u03bb\u03ae\u03c1\u03b7 \u03c0\u03c1\u03cc\u03c3\u03b2\u03b1\u03c3\u03b7 \u03c3\u03b5 \u03cc\u03bb\u03b1 \u03c4\u03b1 \u03b4\u03b5\u03b4\u03bf\u03bc\u03ad\u03bd\u03b1 \u03c4\u03b7\u03c2 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b7\u03c2 \u03ba\u03b1\u03b9 \u03b1\u03bd\u03b1\u03bb\u03b1\u03bc\u03b2\u03ac\u03bd\u03bf\u03c5\u03bd \u03c4\u03b7\u03bd \u03b5\u03c5\u03b8\u03cd\u03bd\u03b7 \u03b3\u03b9\u03b1 \u03c4\u03b7\u03bd \u03b1\u03ba\u03b5\u03c1\u03b1\u03b9\u03cc\u03c4\u03b7\u03c4\u03b1 \u03c4\u03c9\u03bd \u03b4\u03b5\u03b4\u03bf\u03bc\u03ad\u03bd\u03c9\u03bd \u03ba\u03b1\u03b9 \u03c4\u03b7\u03bd \u03b1\u03ba\u03c1\u03af\u03b2\u03b5\u03b9\u03b1 \u03c4\u03b7\u03c2 \u03b1\u03bd\u03ac\u03bb\u03c5\u03c3\u03b7\u03c2 \u03b4\u03b5\u03b4\u03bf\u03bc\u03ad\u03bd\u03c9\u03bd. <\/span><\/p>\n

\u0399\u03b4\u03ad\u03b1 \u03ba\u03b1\u03b9 \u03c3\u03c7\u03ad\u03b4\u03b9\u03bf: <\/span><\/i>\u038c\u03bb\u03bf\u03b9 \u03bf\u03b9 \u03c3\u03c5\u03b3\u03b3\u03c1\u03b1\u03c6\u03b5\u03af\u03c2. <\/span><\/p>\n

\u03a3\u03cd\u03bd\u03c4\u03b1\u03be\u03b7 \u03c4\u03bf\u03c5 \u03c7\u03b5\u03b9\u03c1\u03bf\u03b3\u03c1\u03ac\u03c6\u03bf\u03c5: <\/span><\/i>Carf\u00ec, Landi. <\/span><\/p>\n

\u039a\u03c1\u03b9\u03c4\u03b9\u03ba\u03ae \u03b1\u03bd\u03b1\u03b8\u03b5\u03ce\u03c1\u03b7\u03c3\u03b7 \u03c4\u03bf\u03c5 \u03c7\u03b5\u03b9\u03c1\u03bf\u03b3\u03c1\u03ac\u03c6\u03bf\u03c5 \u03b3\u03b9\u03b1 \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03cc \u03c0\u03bd\u03b5\u03c5\u03bc\u03b1\u03c4\u03b9\u03ba\u03cc \u03c0\u03b5\u03c1\u03b9\u03b5\u03c7\u03cc\u03bc\u03b5\u03bd\u03bf: <\/span><\/i>Bernabei, Landi. <\/span><\/p>\n

\u03a3\u03c4\u03b1\u03c4\u03b9\u03c3\u03c4\u03b9\u03ba\u03ae \u03b1\u03bd\u03ac\u03bb\u03c5\u03c3\u03b7: <\/span><\/i>Carf\u00ec. <\/span><\/p>\n

\u0395\u03c0\u03b9\u03bc\u03ad\u03bb\u03b5\u03b9\u03b1: <\/span><\/i>\u039c\u03c0\u03b5\u03c1\u03bd\u03b1\u03bc\u03c0\u03ad\u03b9, \u039b\u03ac\u03bd\u03c4\u03b9. <\/span><\/p>\n

\u0393\u03bd\u03c9\u03c3\u03c4\u03bf\u03c0\u03bf\u03b9\u03ae\u03c3\u03b5\u03b9\u03c2 \u03a3\u03cd\u03b3\u03ba\u03c1\u03bf\u03c5\u03c3\u03b7\u03c2 \u03a3\u03c5\u03bc\u03c6\u03b5\u03c1\u03cc\u03bd\u03c4\u03c9\u03bd: <\/span><\/strong>\u039a\u03b1\u03bc\u03af\u03b1 \u03b1\u03bd\u03b1\u03c6\u03bf\u03c1\u03ac. <\/span><\/p>\n

\u03a0\u03c1\u03cc\u03c3\u03b8\u03b5\u03c4\u03b5\u03c2 \u03c0\u03bb\u03b7\u03c1\u03bf\u03c6\u03bf\u03c1\u03af\u03b5\u03c2: <\/span><\/strong>\u03a4\u03b1 \u03bc\u03ad\u03bb\u03b7 \u03c4\u03b7\u03c2 \u039f\u03bc\u03ac\u03b4\u03b1\u03c2 \u039c\u03b5\u03bb\u03ad\u03c4\u03b7\u03c2 \u039c\u03b5\u03c4\u03b1-\u03bf\u03be\u03b5\u03af\u03b1\u03c2 \u03a6\u03c1\u03bf\u03bd\u03c4\u03af\u03b4\u03b1\u03c2 Gemelli Against COVID-19 \u03c0\u03b1\u03c1\u03b1\u03c4\u03af\u03b8\u03b5\u03bd\u03c4\u03b1\u03b9 \u03c3\u03c4\u03b7\u03bd \u03b1\u03bd\u03b1\u03c6\u03bf\u03c1\u03ac 5. <\/span><\/p>\n

\n
\u0392\u03b9\u03b2\u03bb\u03b9\u03bf\u03b3\u03c1\u03b1\u03c6\u03b9\u03ba\u03ad\u03c2 \u03b1\u03bd\u03b1\u03c6\u03bf\u03c1\u03ad\u03c2 <\/span><\/div>\n<\/div>\n
\n
<\/a>1. <\/span> <\/p>\n
\u0391\u03bd\u03ce\u03c4\u03b1\u03c4\u03bf \u0399\u03bd\u03c3\u03c4\u03b9\u03c4\u03bf\u03cd\u03c4\u03bf \u03a5\u03b3\u03b5\u03af\u03b1\u03c2. <\/span>\u039f\u03bb\u03bf\u03ba\u03bb\u03b7\u03c1\u03c9\u03bc\u03ad\u03bd\u03b7 \u03b5\u03c0\u03b9\u03c4\u03ae\u03c1\u03b7\u03c3\u03b7 COVID-19 \u03c3\u03c4\u03b7\u03bd \u0399\u03c4\u03b1\u03bb\u03af\u03b1 <\/span><\/i>. \u0394\u03b7\u03bc\u03bf\u03c3\u03b9\u03b5\u03cd\u03b8\u03b7\u03ba\u03b5 \u03c4\u03bf 2020. \u03a0\u03c1\u03cc\u03c3\u03b2\u03b1\u03c3\u03b7 \u03c3\u03c4\u03b9\u03c2 8 \u0399\u03bf\u03c5\u03bd\u03af\u03bf\u03c5 2020. <\/span>https:\/\/www.epicentro.iss.it\/coronavirus\/bollettino\/Infografica_3giugno%20ITA.pdf <\/span><\/a><\/div>\n<\/div>\n
<\/a>2. <\/span> <\/p>\n
Docherty AB, Harrison \u0395\u039c, Green CA, et al; \u0395\u03c1\u03b5\u03c5\u03bd\u03b7\u03c4\u03ad\u03c2 ISARIC4C. \u03a7\u03b1\u03c1\u03b1\u03ba\u03c4\u03b7\u03c1\u03b9\u03c3\u03c4\u03b9\u03ba\u03ac 20 133 \u03b1\u03c3\u03b8\u03b5\u03bd\u03ce\u03bd \u03c3\u03c4\u03bf \u0397\u03bd\u03c9\u03bc\u03ad\u03bd\u03bf \u0392\u03b1\u03c3\u03af\u03bb\u03b5\u03b9\u03bf \u03c3\u03b5 \u03bd\u03bf\u03c3\u03bf\u03ba\u03bf\u03bc\u03b5\u03af\u03bf \u03bc\u03b5 COVID-19 \u03c7\u03c1\u03b7\u03c3\u03b9\u03bc\u03bf\u03c0\u03bf\u03b9\u03ce\u03bd\u03c4\u03b1\u03c2 \u03c4\u03bf \u03a0\u03c1\u03c9\u03c4\u03cc\u03ba\u03bf\u03bb\u03bb\u03bf \u039a\u03bb\u03b9\u03bd\u03b9\u03ba\u03bf\u03cd \u03a7\u03b1\u03c1\u03b1\u03ba\u03c4\u03b7\u03c1\u03b9\u03c3\u03bc\u03bf\u03cd ISARIC WHO: \u03c0\u03c1\u03bf\u03bf\u03c0\u03c4\u03b9\u03ba\u03ae \u03bc\u03b5\u03bb\u03ad\u03c4\u03b7 \u03ba\u03bf\u03cc\u03c1\u03c4\u03b7\u03c2 \u03c0\u03b1\u03c1\u03b1\u03c4\u03ae\u03c1\u03b7\u03c3\u03b7\u03c2. <\/span>BMJ <\/span><\/i>. 2020;369:m1985. doi: <\/span>10.1136\/bmj.m1985 <\/span><\/a>PubMed <\/span><\/a>Google Scholar <\/span><\/a>Crossref <\/span><\/a><\/div>\n<\/div>\n
<\/a>3. <\/span> <\/p>\n
Wang D, Hu B, Hu C, et al. \u039a\u03bb\u03b9\u03bd\u03b9\u03ba\u03ac \u03c7\u03b1\u03c1\u03b1\u03ba\u03c4\u03b7\u03c1\u03b9\u03c3\u03c4\u03b9\u03ba\u03ac 138 \u03bd\u03bf\u03c3\u03b7\u03bb\u03b5\u03c5\u03cc\u03bc\u03b5\u03bd\u03c9\u03bd \u03b1\u03c3\u03b8\u03b5\u03bd\u03ce\u03bd \u03bc\u03b5 \u03c0\u03bd\u03b5\u03c5\u03bc\u03bf\u03bd\u03af\u03b1 2019 \u03bc\u03bf\u03bb\u03c5\u03c3\u03bc\u03ad\u03bd\u03b7 \u03b1\u03c0\u03cc \u03bd\u03ad\u03bf \u03ba\u03bf\u03c1\u03c9\u03bd\u03bf\u03ca\u03cc \u03c3\u03c4\u03b7 \u0393\u03bf\u03c5\u03c7\u03ac\u03bd \u03c4\u03b7\u03c2 \u039a\u03af\u03bd\u03b1\u03c2. <\/span>\u03a4\u0396\u0391\u039c\u0391 <\/span><\/i>. 2020; 323 (13): 1239-1242. doi: <\/span>10.1001\/jama.2020.1585 <\/span><\/a>
\n\u0386\u03c1\u03b8\u03c1\u03bf <\/span><\/a>PubMed <\/span><\/a>Google Scholar <\/span><\/a>Crossref <\/span><\/a><\/div>\n<\/div>\n
<\/a>4. <\/span> <\/p>\n
Landi F, Barillaro C, Bellieni \u0391, et al. \u0397 \u03bd\u03ad\u03b1 \u03c0\u03c1\u03cc\u03ba\u03bb\u03b7\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03b3\u03b7\u03c1\u03b9\u03b1\u03c4\u03c1\u03b9\u03ba\u03ae\u03c2: \u03b7 \u03b4\u03b9\u03ac\u03c3\u03c9\u03c3\u03b7 \u03c4\u03c9\u03bd \u03b1\u03b4\u03cd\u03bd\u03b1\u03bc\u03c9\u03bd \u03b7\u03bb\u03b9\u03ba\u03b9\u03c9\u03bc\u03ad\u03bd\u03c9\u03bd \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd \u03c0\u03b1\u03bd\u03b4\u03b7\u03bc\u03af\u03b1 SARS-CoV-2. <\/span>J Nutr \u03a5\u03b3\u03b5\u03af\u03b1 \u0393\u03ae\u03c1\u03b1\u03bd\u03c3\u03b7 <\/span><\/i>. 2020; 24 (5): 466-470. doi: <\/span>10.1007\/s12603-020-1356-x <\/span><\/a>PubMed <\/span><\/a>Google Scholar <\/span><\/a>Crossref <\/span><\/a><\/div>\n<\/div>\n
<\/a>5. <\/span> <\/p>\n
\u039f\u03bc\u03ac\u03b4\u03b1 \u039c\u03b5\u03bb\u03ad\u03c4\u03b7\u03c2 Gemelli Against COVID-19 Post-Acute Care. \u03a0\u03b1\u03b3\u03ba\u03cc\u03c3\u03bc\u03b9\u03b5\u03c2 \u03c3\u03c4\u03c1\u03b1\u03c4\u03b7\u03b3\u03b9\u03ba\u03ad\u03c2 \u03c5\u03b3\u03b5\u03af\u03b1\u03c2 \u03bc\u03b5\u03c4\u03ac \u03c4\u03bf\u03bd COVID-19: \u03b7 \u03b1\u03bd\u03ac\u03b3\u03ba\u03b7 \u03b3\u03b9\u03b1 \u03bc\u03b9\u03b1 \u03b4\u03b9\u03b5\u03c0\u03b9\u03c3\u03c4\u03b7\u03bc\u03bf\u03bd\u03b9\u03ba\u03ae \u03c0\u03c1\u03bf\u03c3\u03ad\u03b3\u03b3\u03b9\u03c3\u03b7. <\/span>Aging Clin Exp Res <\/span><\/i>. \u0394\u03b7\u03bc\u03bf\u03c3\u03b9\u03b5\u03cd\u03b8\u03b7\u03ba\u03b5 \u03c3\u03c4\u03bf \u03b4\u03b9\u03b1\u03b4\u03af\u03ba\u03c4\u03c5\u03bf \u03c3\u03c4\u03b9\u03c2 11 \u0399\u03bf\u03c5\u03bd\u03af\u03bf\u03c5 2020. doi: <\/span>10.1007\/s40520-020-01616-x <\/span><\/a>PubMed <\/span><\/a>Google Scholar <\/span><\/a><\/div>\n<\/div>\n
<\/a>6. <\/span> <\/p>\n
Metlay JP, Fine MJ, Schulz R, et al. \u039c\u03ad\u03c4\u03c1\u03b7\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03c3\u03c5\u03bc\u03c0\u03c4\u03c9\u03bc\u03b1\u03c4\u03b9\u03ba\u03ae\u03c2 \u03ba\u03b1\u03b9 \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03b9\u03ba\u03ae\u03c2 \u03b1\u03c0\u03bf\u03ba\u03b1\u03c4\u03ac\u03c3\u03c4\u03b1\u03c3\u03b7\u03c2 \u03c3\u03b5 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 \u03c0\u03bd\u03b5\u03c5\u03bc\u03bf\u03bd\u03af\u03b1 \u03c4\u03b7\u03c2 \u03ba\u03bf\u03b9\u03bd\u03cc\u03c4\u03b7\u03c4\u03b1\u03c2. <\/span>J Gen Intern Med <\/span><\/i>. 1997, 12(7):423-430. doi: <\/span>10.1046\/j.1525-1497.1997.00074.x <\/span><\/a>PubMed <\/span><\/a>Google Scholar <\/span><\/a>Crossref <\/span><\/a><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n